Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_020_C20 (250 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O70551|SRPK1_MOUSE Serine/threonine-protein kinase SRPK1... 68 6e-12 sp|Q96SB4|SRPK1_HUMAN Serine/threonine-protein kinase SRPK1... 68 6e-12 sp|Q5RD27|SRPK1_PONPY Serine/threonine-protein kinase SRPK1... 68 6e-12 sp|O54781|SRPK2_MOUSE Serine/threonine-protein kinase SRPK2... 67 1e-11 sp|P78362|SRPK2_HUMAN Serine/threonine-protein kinase SRPK2... 67 1e-11 sp|Q9UPE1|STK23_HUMAN Serine/threonine-protein kinase 23 (M... 65 6e-11 sp|Q9Z0G2|STK23_MOUSE Serine/threonine-protein kinase 23 (M... 64 8e-11 sp|Q03563|SPK1_CAEEL Serine/threonine-protein kinase spk-1 61 9e-10 sp|Q61IS6|SPK1_CAEBR Serine/threonine-protein kinase spk-1 59 3e-09 sp|P36616|DSK1_SCHPO Protein kinase dsk1 (Dis1-suppressing ... 43 3e-04
>sp|O70551|SRPK1_MOUSE Serine/threonine-protein kinase SRPK1 (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1) Length = 648 Score = 68.2 bits (165), Expect = 6e-12 Identities = 34/80 (42%), Positives = 52/80 (65%) Frame = +2 Query: 11 RHTLMGLSYMHNVCQMIHTDIKLENIILTADEDYIRSLAADAILSWKSGVDLPLAAVCNM 190 + L GL Y+H C++IHTDIK ENI+L+ +E YIR LAA+A +SG P + + Sbjct: 194 QQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVST 253 Query: 191 PPKLIQDRSKLNKNQKKRMK 250 P+ + K++KN+KK++K Sbjct: 254 APQ-PKPADKMSKNKKKKLK 272
>sp|Q96SB4|SRPK1_HUMAN Serine/threonine-protein kinase SRPK1 (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1) Length = 826 Score = 68.2 bits (165), Expect = 6e-12 Identities = 34/80 (42%), Positives = 52/80 (65%) Frame = +2 Query: 11 RHTLMGLSYMHNVCQMIHTDIKLENIILTADEDYIRSLAADAILSWKSGVDLPLAAVCNM 190 + L GL Y+H C++IHTDIK ENI+L+ +E YIR LAA+A +SG P + + Sbjct: 365 QQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVST 424 Query: 191 PPKLIQDRSKLNKNQKKRMK 250 P+ + K++KN+KK++K Sbjct: 425 APQ-PKPADKMSKNKKKKLK 443
>sp|Q5RD27|SRPK1_PONPY Serine/threonine-protein kinase SRPK1 (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1) Length = 655 Score = 68.2 bits (165), Expect = 6e-12 Identities = 34/80 (42%), Positives = 52/80 (65%) Frame = +2 Query: 11 RHTLMGLSYMHNVCQMIHTDIKLENIILTADEDYIRSLAADAILSWKSGVDLPLAAVCNM 190 + L GL Y+H C++IHTDIK ENI+L+ +E YIR LAA+A +SG P + + Sbjct: 194 QQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVST 253 Query: 191 PPKLIQDRSKLNKNQKKRMK 250 P+ + K++KN+KK++K Sbjct: 254 APQ-PKPADKMSKNKKKKLK 272
>sp|O54781|SRPK2_MOUSE Serine/threonine-protein kinase SRPK2 (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) (SFRS protein kinase 2) Length = 681 Score = 67.0 bits (162), Expect = 1e-11 Identities = 32/80 (40%), Positives = 52/80 (65%) Frame = +2 Query: 11 RHTLMGLSYMHNVCQMIHTDIKLENIILTADEDYIRSLAADAILSWKSGVDLPLAAVCNM 190 R L GL Y+H+ C++IHTDIK ENI++ D+ Y+R +AA+A K+G P + + Sbjct: 193 RQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVST 252 Query: 191 PPKLIQDRSKLNKNQKKRMK 250 P+ + K++KN+KK++K Sbjct: 253 APQQ-KPIGKISKNKKKKLK 271
>sp|P78362|SRPK2_HUMAN Serine/threonine-protein kinase SRPK2 (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) (SFRS protein kinase 2) Length = 688 Score = 67.0 bits (162), Expect = 1e-11 Identities = 32/80 (40%), Positives = 52/80 (65%) Frame = +2 Query: 11 RHTLMGLSYMHNVCQMIHTDIKLENIILTADEDYIRSLAADAILSWKSGVDLPLAAVCNM 190 R L GL Y+H+ C++IHTDIK ENI++ D+ Y+R +AA+A K+G P + + Sbjct: 195 RQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVST 254 Query: 191 PPKLIQDRSKLNKNQKKRMK 250 P+ + K++KN+KK++K Sbjct: 255 APQQ-KPIGKISKNKKKKLK 273
>sp|Q9UPE1|STK23_HUMAN Serine/threonine-protein kinase 23 (Muscle-specific serine kinase 1) (MSSK-1) Length = 533 Score = 64.7 bits (156), Expect = 6e-11 Identities = 33/80 (41%), Positives = 51/80 (63%) Frame = +2 Query: 11 RHTLMGLSYMHNVCQMIHTDIKLENIILTADEDYIRSLAADAILSWKSGVDLPLAAVCNM 190 R L GL Y+H C++IHTDIK ENI+L + YIR LAA+A ++G P ++ + Sbjct: 193 RQVLHGLDYLHTKCKIIHTDIKPENILLCVGDAYIRRLAAEATEWQQAGAPPPSRSIVST 252 Query: 191 PPKLIQDRSKLNKNQKKRMK 250 P+ + KL+KN++K+M+ Sbjct: 253 APQEVL-TGKLSKNKRKKMR 271
>sp|Q9Z0G2|STK23_MOUSE Serine/threonine-protein kinase 23 (Muscle-specific serine kinase 1) (MSSK-1) Length = 565 Score = 64.3 bits (155), Expect = 8e-11 Identities = 34/80 (42%), Positives = 50/80 (62%) Frame = +2 Query: 11 RHTLMGLSYMHNVCQMIHTDIKLENIILTADEDYIRSLAADAILSWKSGVDLPLAAVCNM 190 R L GL Y+H C++IHTDIK ENI+L + YIR LAA+A +SG P + + Sbjct: 192 RQVLHGLDYLHTKCKIIHTDIKPENILLCVGDAYIRRLAAEATEWQQSGAQPPSRSTVST 251 Query: 191 PPKLIQDRSKLNKNQKKRMK 250 P+ + KL+KN++K+M+ Sbjct: 252 APQEVL-IGKLSKNKRKKMR 270
>sp|Q03563|SPK1_CAEEL Serine/threonine-protein kinase spk-1 Length = 1003 Score = 60.8 bits (146), Expect = 9e-10 Identities = 30/81 (37%), Positives = 49/81 (60%), Gaps = 1/81 (1%) Frame = +2 Query: 11 RHTLMGLSYMHNVCQMIHTDIKLENIILTADEDYIRSLAADAILSWKSGVDLPLAAVCNM 190 R L L YMH C +IHTDIK EN+++T + I+ +A A+++ K + + +AV Sbjct: 536 RQVLEALGYMHEKCGIIHTDIKPENVLITMSREEIKIMAQHAVVARKMNMKMSGSAVSTA 595 Query: 191 PPKLIQ-DRSKLNKNQKKRMK 250 P L++ + + KN+KK+MK Sbjct: 596 PDHLVKMAQENMTKNKKKKMK 616
>sp|Q61IS6|SPK1_CAEBR Serine/threonine-protein kinase spk-1 Length = 771 Score = 58.9 bits (141), Expect = 3e-09 Identities = 29/81 (35%), Positives = 49/81 (60%), Gaps = 1/81 (1%) Frame = +2 Query: 11 RHTLMGLSYMHNVCQMIHTDIKLENIILTADEDYIRSLAADAILSWKSGVDLPLAAVCNM 190 + L L YMH C +IHTDIK EN+++T + I+ +A A+++ K + + +AV Sbjct: 248 KQILEALRYMHEKCGIIHTDIKPENVLITMSREEIKIMAQHAVVARKMNMKMSGSAVSTA 307 Query: 191 PPKLIQ-DRSKLNKNQKKRMK 250 P L++ + + KN+KK+MK Sbjct: 308 PDHLVKMAQENMTKNKKKKMK 328
>sp|P36616|DSK1_SCHPO Protein kinase dsk1 (Dis1-suppressing protein kinase) Length = 544 Score = 42.7 bits (99), Expect = 3e-04 Identities = 17/42 (40%), Positives = 28/42 (66%) Frame = +2 Query: 20 LMGLSYMHNVCQMIHTDIKLENIILTADEDYIRSLAADAILS 145 L+ L Y+H C +IHTD+K EN+++ D+D ++ + A A S Sbjct: 198 LIALDYLHRECGIIHTDLKPENVLICIDQDALQHIEAPATTS 239
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,706,906 Number of Sequences: 369166 Number of extensions: 466325 Number of successful extensions: 1673 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1651 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1671 length of database: 68,354,980 effective HSP length: 53 effective length of database: 58,564,025 effective search space used: 1698356725 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)