Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_C12
(629 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O61998|HSP90_BRUPA Heat shock protein 90 243 3e-64
sp|P07901|HS90A_MOUSE Heat shock protein HSP 90-alpha (HSP ... 242 5e-64
sp|P07900|HS90A_HUMAN Heat shock protein HSP 90-alpha (HSP 86) 241 9e-64
sp|P46633|HS90A_CRIGR Heat shock protein HSP 90-alpha (HSP 86) 241 1e-63
sp|O02705|HS90A_PIG Heat shock protein HSP 90-alpha (HSP 86) 240 2e-63
sp|P11501|HS90A_CHICK Heat shock protein HSP 90-alpha 239 4e-63
sp|P08238|HS90B_HUMAN Heat shock protein HSP 90-beta (HSP 8... 238 7e-63
sp|Q9GKX8|HS90B_HORSE Heat shock protein HSP 90-beta (HSP 84) 238 9e-63
sp|P11499|HS90B_MOUSE Heat shock protein HSP 90-beta (HSP 8... 238 9e-63
sp|Q90474|HS90A_BRARE Heat shock protein HSP 90-alpha 235 6e-62
>sp|O61998|HSP90_BRUPA Heat shock protein 90
Length = 717
Score = 243 bits (620), Expect = 3e-64
Identities = 126/166 (75%), Positives = 147/166 (88%), Gaps = 5/166 (3%)
Frame = +2
Query: 86 LCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAA 265
LCKVMKDIL+KKVEKV VSNRLVSSPCCIVTS+YGWSANMERIMKAQALRDSSTMGYMAA
Sbjct: 553 LCKVMKDILEKKVEKVAVSNRLVSSPCCIVTSEYGWSANMERIMKAQALRDSSTMGYMAA 612
Query: 266 KKHLEINPDHSIMKTLKARVDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHR 445
KKHLEINPDHS++K L+ RV+ADKNDK+VKDLV+LL+ET+LLSSGF+LEDPQ+H +RI+R
Sbjct: 613 KKHLEINPDHSVIKALRERVEADKNDKTVKDLVVLLFETALLSSGFSLEDPQLHASRIYR 672
Query: 446 MIKLGLGI-EDDDVEMDATEAGD----VPVVASTAEEDAGKMEEVD 568
MIKLGL I ED++ E A+ +G+ VP + AEEDA +MEEVD
Sbjct: 673 MIKLGLDITEDEEEEAIASVSGEKDECVPNLVG-AEEDASRMEEVD 717
>sp|P07901|HS90A_MOUSE Heat shock protein HSP 90-alpha (HSP 86) (Tumor specific
transplantation 86 kDa antigen) (TSTA)
Length = 733
Score = 242 bits (618), Expect = 5e-64
Identities = 120/164 (73%), Positives = 143/164 (87%), Gaps = 3/164 (1%)
Frame = +2
Query: 86 LCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAA 265
LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS YGW+ANMERIMKAQALRD+STMGYMAA
Sbjct: 572 LCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAA 631
Query: 266 KKHLEINPDHSIMKTLKARVDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHR 445
KKHLEINPDHSI++TL+ + +ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ H NRI+R
Sbjct: 632 KKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYR 691
Query: 446 MIKLGLGIEDDDVEMDATEAG---DVPVVASTAEEDAGKMEEVD 568
MIKLGLGI++DD +D T A ++P + ++D +MEEVD
Sbjct: 692 MIKLGLGIDEDDPTVDDTSAAVTEEMPPL--EGDDDTSRMEEVD 733
>sp|P07900|HS90A_HUMAN Heat shock protein HSP 90-alpha (HSP 86)
Length = 732
Score = 241 bits (616), Expect = 9e-64
Identities = 120/164 (73%), Positives = 142/164 (86%), Gaps = 3/164 (1%)
Frame = +2
Query: 86 LCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAA 265
LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS YGW+ANMERIMKAQALRD+STMGYMAA
Sbjct: 571 LCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAA 630
Query: 266 KKHLEINPDHSIMKTLKARVDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHR 445
KKHLEINPDHSI++TL+ + +ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ H NRI+R
Sbjct: 631 KKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYR 690
Query: 446 MIKLGLGIEDDDVEMDATEAG---DVPVVASTAEEDAGKMEEVD 568
MIKLGLGI++DD D T A ++P + ++D +MEEVD
Sbjct: 691 MIKLGLGIDEDDPTADDTSAAVTEEMPPL--EGDDDTSRMEEVD 732
>sp|P46633|HS90A_CRIGR Heat shock protein HSP 90-alpha (HSP 86)
Length = 733
Score = 241 bits (614), Expect = 1e-63
Identities = 119/164 (72%), Positives = 143/164 (87%), Gaps = 3/164 (1%)
Frame = +2
Query: 86 LCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAA 265
LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS YGW+ANMERI+KAQALRD+STMGYMAA
Sbjct: 572 LCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIIKAQALRDNSTMGYMAA 631
Query: 266 KKHLEINPDHSIMKTLKARVDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHR 445
KKHLEINPDHSI++TL+ + +ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ H NRI+R
Sbjct: 632 KKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYR 691
Query: 446 MIKLGLGIEDDDVEMDATEAG---DVPVVASTAEEDAGKMEEVD 568
MIKLGLGI++DD +D T A ++P + ++D +MEEVD
Sbjct: 692 MIKLGLGIDEDDPTVDDTSAAVTEEMPPL--EGDDDTSRMEEVD 733
>sp|O02705|HS90A_PIG Heat shock protein HSP 90-alpha (HSP 86)
Length = 733
Score = 240 bits (612), Expect = 2e-63
Identities = 119/164 (72%), Positives = 142/164 (86%), Gaps = 3/164 (1%)
Frame = +2
Query: 86 LCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAA 265
LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS YGW+ANMERIMKAQALRD+STMGYMAA
Sbjct: 572 LCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAA 631
Query: 266 KKHLEINPDHSIMKTLKARVDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHR 445
KKHLEINPDHSI++TL+ + +ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ H NRI+R
Sbjct: 632 KKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYR 691
Query: 446 MIKLGLGIEDDDVEMDATEAG---DVPVVASTAEEDAGKMEEVD 568
MIKLGLGI++DD D + A ++P + ++D +MEEVD
Sbjct: 692 MIKLGLGIDEDDPTADDSSAAVTEEMPPL--EGDDDTSRMEEVD 733
>sp|P11501|HS90A_CHICK Heat shock protein HSP 90-alpha
Length = 728
Score = 239 bits (610), Expect = 4e-63
Identities = 118/162 (72%), Positives = 140/162 (86%), Gaps = 1/162 (0%)
Frame = +2
Query: 86 LCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAA 265
LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS YGW+ANMERIMKAQALRD+STMGYMAA
Sbjct: 567 LCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAA 626
Query: 266 KKHLEINPDHSIMKTLKARVDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHR 445
KKHLEINPDHSI++TL+ + +ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ H NRI+R
Sbjct: 627 KKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYR 686
Query: 446 MIKLGLGIEDDDVEM-DATEAGDVPVVASTAEEDAGKMEEVD 568
MIKLGLGI++DD +A+ A + ++D +MEEVD
Sbjct: 687 MIKLGLGIDEDDTAAEEASPAVTEEMPPLEGDDDTSRMEEVD 728
>sp|P08238|HS90B_HUMAN Heat shock protein HSP 90-beta (HSP 84) (HSP 90)
Length = 724
Score = 238 bits (608), Expect = 7e-63
Identities = 118/164 (71%), Positives = 143/164 (87%), Gaps = 3/164 (1%)
Frame = +2
Query: 86 LCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAA 265
LCK+MK+ILDKKVEKVT+SNRLVSSPCCIVTS YGW+ANMERIMKAQALRD+STMGYM A
Sbjct: 563 LCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMA 622
Query: 266 KKHLEINPDHSIMKTLKARVDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHR 445
KKHLEINPDH I++TL+ + +ADKNDK+VKDLV+LL+ET+LLSSGF+LEDPQ H NRI+R
Sbjct: 623 KKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYR 682
Query: 446 MIKLGLGIEDDDV---EMDATEAGDVPVVASTAEEDAGKMEEVD 568
MIKLGLGI++D+V E +A ++P + +EDA +MEEVD
Sbjct: 683 MIKLGLGIDEDEVAAEEPNAAVPDEIPPL--EGDEDASRMEEVD 724
>sp|Q9GKX8|HS90B_HORSE Heat shock protein HSP 90-beta (HSP 84)
Length = 724
Score = 238 bits (607), Expect = 9e-63
Identities = 118/164 (71%), Positives = 142/164 (86%), Gaps = 3/164 (1%)
Frame = +2
Query: 86 LCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAA 265
LCK+MK+ILDKKVEKVT+SNRLVSSPCCIVTS YGW+ANMERIMKAQALRD+STMGYM A
Sbjct: 563 LCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMA 622
Query: 266 KKHLEINPDHSIMKTLKARVDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHR 445
KKHLEINPDH I++TL+ + +ADKNDK+VKDLV+LL+ET+LLSSGF+LEDPQ H NRI+R
Sbjct: 623 KKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYR 682
Query: 446 MIKLGLGIEDDDV---EMDATEAGDVPVVASTAEEDAGKMEEVD 568
MIKLGLGI++D+V E A ++P + +EDA +MEEVD
Sbjct: 683 MIKLGLGIDEDEVAAEEPSAAVPDEIPPL--EGDEDASRMEEVD 724
>sp|P11499|HS90B_MOUSE Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific
transplantation 84 kDa antigen) (TSTA)
Length = 724
Score = 238 bits (607), Expect = 9e-63
Identities = 118/164 (71%), Positives = 142/164 (86%), Gaps = 3/164 (1%)
Frame = +2
Query: 86 LCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAA 265
LCK+MK+ILDKKVEKVT+SNRLVSSPCCIVTS YGW+ANMERIMKAQALRD+STMGYM A
Sbjct: 563 LCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMA 622
Query: 266 KKHLEINPDHSIMKTLKARVDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHR 445
KKHLEINPDH I++TL+ + +ADKNDK+VKDLV+LL+ET+LLSSGF+LEDPQ H NRI+R
Sbjct: 623 KKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYR 682
Query: 446 MIKLGLGIEDDDV---EMDATEAGDVPVVASTAEEDAGKMEEVD 568
MIKLGLGI++D+V E A ++P + +EDA +MEEVD
Sbjct: 683 MIKLGLGIDEDEVTAEEPSAAVPDEIPPL--EGDEDASRMEEVD 724
>sp|Q90474|HS90A_BRARE Heat shock protein HSP 90-alpha
Length = 726
Score = 235 bits (600), Expect = 6e-62
Identities = 116/164 (70%), Positives = 140/164 (85%), Gaps = 3/164 (1%)
Frame = +2
Query: 86 LCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAA 265
LCK+MKDILDKK+EKVTVSNRLVSSPCCIVTS YGW+ANMERIMK+QALRD+STMGYM A
Sbjct: 565 LCKIMKDILDKKIEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKSQALRDNSTMGYMTA 624
Query: 266 KKHLEINPDHSIMKTLKARVDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHR 445
KKHLEINP H I++TL+ + +A+KNDK+VKDLV+LL+ET+LLSSGFTL+DPQ H NRI+R
Sbjct: 625 KKHLEINPAHPIVETLREKAEAEKNDKAVKDLVILLFETALLSSGFTLDDPQTHANRIYR 684
Query: 446 MIKLGLGIEDDD---VEMDATEAGDVPVVASTAEEDAGKMEEVD 568
MIKLGLGI+DDD E+ D+PV+ ++D +MEEVD
Sbjct: 685 MIKLGLGIDDDDSVVEEISQPAEEDMPVL--EGDDDTSRMEEVD 726
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,288,121
Number of Sequences: 369166
Number of extensions: 962771
Number of successful extensions: 2990
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2867
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2918
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5023626210
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)