Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_A12
(941 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P53297|PBP1_YEAST PAB1-binding protein 1 58 4e-08
sp|Q7TQH0|ATX2L_MOUSE Ataxin-2-like protein 46 1e-04
sp|Q8WWM7|ATX2L_HUMAN Ataxin-2-like protein (Ataxin-2 domai... 45 3e-04
sp|Q99700|ATX2_HUMAN Ataxin-2 (Spinocerebellar ataxia type ... 45 3e-04
sp|O70305|ATX2_MOUSE Ataxin-2 (Spinocerebellar ataxia type ... 44 5e-04
sp|P35727|YKG1_YEAST Hypothetical 13.5 kDa protein in MSN4-... 37 0.11
sp|Q96L73|NSD1_HUMAN Histone-lysine N-methyltransferase, H3... 36 0.18
sp|P14873|MAP1B_MOUSE Microtubule-associated protein 1B (MA... 35 0.31
sp|P40949|YQXM_BACSU Hypothetical protein yqxM 34 0.52
sp|P34216|YBE7_YEAST Hypothetical 150.8 kDa protein in SEC1... 34 0.52
>sp|P53297|PBP1_YEAST PAB1-binding protein 1
Length = 722
Score = 57.8 bits (138), Expect = 4e-08
Identities = 69/272 (25%), Positives = 120/272 (44%), Gaps = 35/272 (12%)
Frame = +1
Query: 22 RNQDSHVIYSGDRKKSLCDLSIYTIARFLMGNEVQIITQFDRYEGVLRTFD-STCLGLSK 198
+N S + + ++ D Y +A + + +T +Y G+L + + + G+
Sbjct: 32 QNNSSMFYENPEITRNFDDRQDYLLANSIGSDVTVTVTSGVKYTGLLVSCNLESTNGIDV 91
Query: 199 VFVF----DNGLSDSIP-IIKTQLEFKEVLLKDILLIKM----LNGNGKLESVIIDQEIS 351
V F D+G+SDS+ + KT E + +D+ +++ L+ + K E+ +
Sbjct: 92 VLRFPRVADSGVSDSVDDLAKTLGETLLIHGEDVAELELKNIDLSLDEKWENSKAQETTP 151
Query: 352 QRKQLFKPNLNEDKNLVPYF-----------DEEETQLHXXXXXXXLN-------ASLKS 477
R + K +N + N V F + +E +L +L+
Sbjct: 152 ARTNIEKERVNGESNEVTKFRTDVDISGSGREIKERKLEKWTPEEGAEHFDINKGKALED 211
Query: 478 DQNCWYDPETMLKENEERFNVKKTWNSETMEEYTTQIDKSDPLLKEKMEYAERIAKEIEN 657
D W NE++F VK T++ YTT+I+K DP ++++ AERIAKEIE+
Sbjct: 212 DSASW----DQFAVNEKKFGVKSTFDEHL---YTTKINKDDPNYSKRLQEAERIAKEIES 264
Query: 658 ESNM-------KRGRIPDDSGEQDEEIMFSAV 732
+ RG I DDSG DEE ++S V
Sbjct: 265 QGTSGNIHIAEDRGIIIDDSG-LDEEDLYSGV 295
>sp|Q7TQH0|ATX2L_MOUSE Ataxin-2-like protein
Length = 1049
Score = 46.2 bits (108), Expect = 1e-04
Identities = 35/116 (30%), Positives = 62/116 (53%), Gaps = 10/116 (8%)
Frame = +1
Query: 469 LKSDQNCWYDPETMLKENEERFNVKKTWNSETMEEYTTQIDK-SDPLLKEKMEYAERIAK 645
L+SD + +DP M K NEE + VK T++S ++ YT ++K + +++ A ++A+
Sbjct: 241 LESDMSNGWDPNEMFKFNEENYGVKTTYDS-SLSSYTVPLEKDNSEEFRQRELRAAQLAR 299
Query: 646 EIENESNMK-RGRIPDDSGEQDEEIMFSAVM--------PSVVNKSETPVATPIRL 786
EIE+ + R + +D G +EE SAV PS+V++ + P R+
Sbjct: 300 EIESSPQYRLRIAMENDDGRTEEE-KHSAVQRQGSGRESPSLVSREGKYIPLPQRV 354
>sp|Q8WWM7|ATX2L_HUMAN Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related
protein)
Length = 1075
Score = 45.1 bits (105), Expect = 3e-04
Identities = 27/84 (32%), Positives = 49/84 (58%), Gaps = 2/84 (2%)
Frame = +1
Query: 469 LKSDQNCWYDPETMLKENEERFNVKKTWNSETMEEYTTQIDK-SDPLLKEKMEYAERIAK 645
L+SD + +DP M K NEE + VK T++S ++ YT ++K + +++ A ++A+
Sbjct: 243 LESDMSNGWDPNEMFKFNEENYGVKTTYDS-SLSSYTVPLEKDNSEEFRQRELRAAQLAR 301
Query: 646 EIENESNMK-RGRIPDDSGEQDEE 714
EIE+ + R + +D G +EE
Sbjct: 302 EIESSPQYRLRIAMENDDGRTEEE 325
>sp|Q99700|ATX2_HUMAN Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide
repeat-containing gene 13 protein)
Length = 1312
Score = 45.1 bits (105), Expect = 3e-04
Identities = 50/201 (24%), Positives = 95/201 (47%), Gaps = 6/201 (2%)
Frame = +1
Query: 148 YEGVLRTFDSTCLGLSKVFVFDNGLSDSIPIIKTQLEFKEVLLK--DILLI--KMLNGNG 315
YEGV +T+ C + + S S P K + + +L K D +++ K ++ +
Sbjct: 289 YEGVFKTYSPKCDLVLDAAHEKSTESSSGP--KREEIMESILFKCSDFVVVQFKDMDSSY 346
Query: 316 KLESVIIDQEISQRKQLFKPNLNEDKNLVPYFDEEETQLHXXXXXXXLNASLKSDQNCWY 495
D IS + +++K+L P+ E T +L++D + +
Sbjct: 347 AKRDAFTDSAISAKVN----GEHKEKDLEPWDAGELTANEELE-------ALENDVSNGW 395
Query: 496 DPETMLKENEERFNVKKTWNSETMEEYTTQI--DKSDPLLKEKMEYAERIAKEIENESNM 669
DP M + NEE + V T++S ++ YT + D S+ LK + A ++A+EIE+ +
Sbjct: 396 DPNDMFRYNEENYGVVSTYDS-SLSSYTVPLERDNSEEFLKREAR-ANQLAEEIESSAQY 453
Query: 670 KRGRIPDDSGEQDEEIMFSAV 732
K R+ ++ ++ EE ++AV
Sbjct: 454 K-ARVALENDDRSEEEKYTAV 473
>sp|O70305|ATX2_MOUSE Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog)
Length = 1285
Score = 44.3 bits (103), Expect = 5e-04
Identities = 28/90 (31%), Positives = 53/90 (58%), Gaps = 2/90 (2%)
Frame = +1
Query: 469 LKSDQNCWYDPETMLKENEERFNVKKTWNSETMEEYTTQI--DKSDPLLKEKMEYAERIA 642
L++D + +DP M + NEE + V T++S ++ YT + D S+ LK + A ++A
Sbjct: 357 LENDVSNGWDPNDMFRYNEENYGVVSTYDS-SLSSYTVPLERDNSEEFLKREAR-ANQLA 414
Query: 643 KEIENESNMKRGRIPDDSGEQDEEIMFSAV 732
+EIE+ + K R+ ++ ++ EE ++AV
Sbjct: 415 EEIESSAQYK-ARVALENDDRSEEEKYTAV 443
>sp|P35727|YKG1_YEAST Hypothetical 13.5 kDa protein in MSN4-FBA1 intergenic region
Length = 113
Score = 36.6 bits (83), Expect = 0.11
Identities = 18/55 (32%), Positives = 30/55 (54%)
Frame = +1
Query: 502 ETMLKENEERFNVKKTWNSETMEEYTTQIDKSDPLLKEKMEYAERIAKEIENESN 666
E L+E E +F +K + +E +ID +L++K+ Y ER+ KE+E N
Sbjct: 41 EAWLEELENKFKLKDDVELDDVENLRAEIDMKLNMLEDKVSYYERLYKELEEFQN 95
>sp|Q96L73|NSD1_HUMAN Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20
specific (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear
receptor binding SET domain containing protein 1)
(NR-binding SET domain containing protein) (Androgen
receptor-associated coregulator 267)
Length = 2696
Score = 35.8 bits (81), Expect = 0.18
Identities = 24/89 (26%), Positives = 37/89 (41%)
Frame = +1
Query: 499 PETMLKENEERFNVKKTWNSETMEEYTTQIDKSDPLLKEKMEYAERIAKEIENESNMKRG 678
PE ++ ++R W E EEY QI K+ E +++ E ES + RG
Sbjct: 1263 PEPAVRSEKKRLRKPSKWLLEYTEEYD-QIFAPKKKQKKVQEQVHKVSSRCEEESLLARG 1321
Query: 679 RIPDDSGEQDEEIMFSAVMPSVVNKSETP 765
R + + DE + S V + E P
Sbjct: 1322 RSSAQNKQVDENSLISTKEEPPVLEREAP 1350
>sp|P14873|MAP1B_MOUSE Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X))
[Contains: MAP1 light chain LC1]
Length = 2464
Score = 35.0 bits (79), Expect = 0.31
Identities = 34/164 (20%), Positives = 65/164 (39%), Gaps = 7/164 (4%)
Frame = +1
Query: 310 NGKLESVIIDQEISQRKQL-FKPNLNEDKNLVPYFDEEETQLHXXXXXXXLNASLKSDQN 486
+ K E + E+++++ KP + +DK + E +T+L +K +
Sbjct: 608 SSKEEQSPVKAEVAEKQATESKPKVTKDKVVKK---EIKTKLEEKKEEKPKKEVVKKEDK 664
Query: 487 CWYDPETMLKENEERFNVKKTWNSETMEEYTTQIDKSDPLLKEKMEYAERIAKEIENESN 666
+ ++ E + +KK E +E ++ K PL K E + KE++ E
Sbjct: 665 TPLKKDEKPRKEEVKKEIKKEIKKEERKELKKEVKKETPLKDAKKEVKKEEKKEVKKEEK 724
Query: 667 MKRGRIPDDSGE------QDEEIMFSAVMPSVVNKSETPVATPI 780
+ I S + Q + SA+ P V K E+ P+
Sbjct: 725 EPKKEIKKISKDIKKSTPQSDTKKPSALKPKVAKKEESTKKEPL 768
>sp|P40949|YQXM_BACSU Hypothetical protein yqxM
Length = 253
Score = 34.3 bits (77), Expect = 0.52
Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +1
Query: 490 WYDPETMLKENEERFNVKKTWNSETMEEY-TTQIDKSDPLLKEKMEYAERIAKEIENESN 666
W +P + K +E+ KK S+ +E TTQ D + +KE+ E + KE E +S+
Sbjct: 179 WSEPMRLAKCDEKPTVPKKETKSDVKKENETTQKDIPEKTMKEETS-QEAVTKEKETQSD 237
Query: 667 MKRGRIPDDSGEQDEE 714
K +SGE+DE+
Sbjct: 238 QK------ESGEEDEK 247
>sp|P34216|YBE7_YEAST Hypothetical 150.8 kDa protein in SEC17-QCR1 intergenic region
Length = 1381
Score = 34.3 bits (77), Expect = 0.52
Identities = 35/169 (20%), Positives = 76/169 (44%), Gaps = 14/169 (8%)
Frame = +1
Query: 232 IPIIKTQLEFKEVLLKDILLIKMLNGNGKLESVI-------------IDQEISQRKQLFK 372
+ + QLE +V + + L K ++G G+ SV ++++ +Q + ++
Sbjct: 746 VDVNSKQLELNQVTVAN--LQKEIDGLGEKISVYLTKQKELNDYQKTVEEQHAQLQAKYQ 803
Query: 373 PNLNEDKNLVPYFDEEETQLHXXXXXXXLNASLKSDQNCWYDPETMLKENEERFNVKKTW 552
N+D +L + E QL N ++ +N ++ + L+E + + +K
Sbjct: 804 DLSNKDTDLT----DREKQLEER------NRQIEEQENLYHQHVSKLQEMFDDLSQRKA- 852
Query: 553 NSETMEEYTTQIDKSDPLLKEK-MEYAERIAKEIENESNMKRGRIPDDS 696
+K+D LKE+ +EYA + + E + N+ G++P+D+
Sbjct: 853 ----------SFEKADQELKERNIEYANNVRELSERQMNLAMGQLPEDA 891
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.313 0.131 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,595,405
Number of Sequences: 369166
Number of extensions: 1787554
Number of successful extensions: 4507
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4330
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4499
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9750928390
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)