Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_A08
(874 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9UG63|ABCF2_HUMAN ATP-binding cassette sub-family F mem... 385 e-107
sp|Q99LE6|ABCF2_MOUSE ATP-binding cassette sub-family F mem... 385 e-107
sp|P40024|YEM6_YEAST Probable ATP-dependent transporter YER... 252 8e-67
sp|P43535|GCN20_YEAST Protein GCN20 214 2e-55
sp|Q6MG08|ABCF1_RAT ATP-binding cassette sub-family F membe... 189 1e-47
sp|Q6P542|ABCF1_MOUSE ATP-binding cassette sub-family F mem... 187 3e-47
sp|Q8NE71|ABCF1_HUMAN ATP-binding cassette sub-family F mem... 187 4e-47
sp|Q7YR37|ABCF1_PANTR ATP-binding cassette sub-family F mem... 187 4e-47
sp|Q767L0|ABCF1_PIG ATP-binding cassette sub-family F member 1 186 7e-47
sp|P63390|YHES_ECO57 Hypothetical ABC transporter ATP-bindi... 142 9e-34
>sp|Q9UG63|ABCF2_HUMAN ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC
transporter 2)
Length = 623
Score = 385 bits (989), Expect = e-107
Identities = 183/269 (68%), Positives = 223/269 (82%)
Frame = +2
Query: 2 GSRKLARQAQSKEKTLKKMVDGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGA 181
GS KLARQAQSKEKTL+KM+ GLT++V+ +K L F FP CG+IPPPVI VQNVSFKY
Sbjct: 348 GSAKLARQAQSKEKTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTK 407
Query: 182 NKPLIYDNIDFGVDLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQ 361
+ P IY+N++FG+DLDTRVALVGPNGAGKSTLLKL+ EL PTDG+IR+HS +IGRYHQ
Sbjct: 408 DGPCIYNNLEFGIDLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQ 467
Query: 362 HLHEILDLNSTALEWMMKSFPHIKEKDEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIF 541
HL E LDL+ + LE+MMK +P IKEK+EMRK +GRYGLTG QQ+ PI++LSDGQ+CR+
Sbjct: 468 HLQEQLDLDLSPLEYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCL 527
Query: 542 AWLAEGCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCD 721
AWLA PHML LDEPTNHLD+ETID+LADAINEFEGG++LVSHDFRLI +VA+EIWVC+
Sbjct: 528 AWLAWQNPHMLFLDEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCE 587
Query: 722 HGAVTKWPGDIYSYKTSLIKEIEREHTRM 808
+TKWPGDI +YK L ++ E ++
Sbjct: 588 KQTITKWPGDILAYKEHLKSKLVDEEPQL 616
Score = 60.8 bits (146), Expect = 5e-09
Identities = 63/221 (28%), Positives = 89/221 (40%), Gaps = 25/221 (11%)
Frame = +2
Query: 233 RVALVGPNGAGKSTLLKLIAS----------------ELEPTDGLIRRHSKCRIGRYHQH 364
R L+G NG GKS LL I E+ P+D H +
Sbjct: 113 RYGLIGLNGIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSDKT-PLHCVMEVDTERAM 171
Query: 365 LH---EILDLNSTALEWMMKSFPHIKEKD----EMRKK--LGRYGLTGGQQICPIKSLSD 517
L E L E +M+ + ++E D EMR L G T Q +K S
Sbjct: 172 LEKEAERLAHEDAECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSG 231
Query: 518 GQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRV 697
G R R+ A P MLLLDEPTNHLDL+ L + + F+ L+LVSH + V
Sbjct: 232 GWRMRVALARALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGV 291
Query: 698 AEEIWVCDHGAVTKWPGDIYSYKTSLIKEIEREHTRMMTER 820
I + + + G+ Y + ++ E + R E+
Sbjct: 292 CTNIIHMHNKKLKYYTGNYDQYVKTRLELEENQMKRFHWEQ 332
>sp|Q99LE6|ABCF2_MOUSE ATP-binding cassette sub-family F member 2
Length = 628
Score = 385 bits (989), Expect = e-107
Identities = 183/269 (68%), Positives = 223/269 (82%)
Frame = +2
Query: 2 GSRKLARQAQSKEKTLKKMVDGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGA 181
GS KLARQAQSKEKTL+KM+ GLT++V+ +K L F FP CG+IPPPVI VQNVSFKY
Sbjct: 353 GSAKLARQAQSKEKTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTK 412
Query: 182 NKPLIYDNIDFGVDLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQ 361
+ P IY+N++FG+DLDTRVALVGPNGAGKSTLLKL+ EL PTDG+IR+HS +IGRYHQ
Sbjct: 413 DGPCIYNNLEFGIDLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQ 472
Query: 362 HLHEILDLNSTALEWMMKSFPHIKEKDEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIF 541
HL E LDL+ + LE+MMK +P IKEK+EMRK +GRYGLTG QQ+ PI++LSDGQ+CR+
Sbjct: 473 HLQEQLDLDLSPLEYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCL 532
Query: 542 AWLAEGCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCD 721
AWLA PHML LDEPTNHLD+ETID+LADAINEFEGG++LVSHDFRLI +VA+EIWVC+
Sbjct: 533 AWLAWQNPHMLFLDEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCE 592
Query: 722 HGAVTKWPGDIYSYKTSLIKEIEREHTRM 808
+TKWPGDI +YK L ++ E ++
Sbjct: 593 KQTITKWPGDILAYKEHLKSKLVDEEPQL 621
Score = 58.2 bits (139), Expect = 3e-08
Identities = 62/220 (28%), Positives = 87/220 (39%), Gaps = 24/220 (10%)
Frame = +2
Query: 233 RVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCR---------------IGRYHQHL 367
R L+G NG GKS LL I P I + R + L
Sbjct: 118 RYGLIGLNGIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSEKTPLQCVMEVDTERAML 177
Query: 368 H---EILDLNSTALEWMMKSFPHIKEKD----EMRKK--LGRYGLTGGQQICPIKSLSDG 520
E L E +M+ + ++E D EMR L G T Q +K S G
Sbjct: 178 EREAERLAHEDAECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGG 237
Query: 521 QRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVA 700
R R+ A P MLLLDEPTNHLDL+ L + + F+ L+LVSH + V
Sbjct: 238 WRMRVALARALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVC 297
Query: 701 EEIWVCDHGAVTKWPGDIYSYKTSLIKEIEREHTRMMTER 820
I + + + G+ Y + ++ E + R E+
Sbjct: 298 TNIIHMHNKKLKYYTGNYDQYVKTRLELEENQMKRFHWEQ 337
>sp|P40024|YEM6_YEAST Probable ATP-dependent transporter YER036C
Length = 610
Score = 252 bits (644), Expect = 8e-67
Identities = 125/260 (48%), Positives = 180/260 (69%), Gaps = 2/260 (0%)
Frame = +2
Query: 14 LARQAQSKEKTLKKMVDGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGAN-KP 190
L +QA+S++K L KM GL Q V+ +K F FP +PPPV+ ++SF Y +N
Sbjct: 349 LVKQAKSRQKILDKMEADGLVQPVVPDKVFSFRFPQVERLPPPVLAFDDISFHYESNPSE 408
Query: 191 LIYDNIDFGVDLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQHLH 370
+Y++++FGVD+D+R+ALVGPNG GKSTLLK++ EL P G + RH+ ++G Y QH
Sbjct: 409 NLYEHLNFGVDMDSRIALVGPNGVGKSTLLKIMTGELTPQSGRVSRHTHVKLGVYSQHSQ 468
Query: 371 EILDLNSTALEWMMKSFPHIKEKDEM-RKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAW 547
+ LDL +ALE++ + +I + + R +LGRYGLTG Q + +LS+GQR R++FA
Sbjct: 469 DQLDLTKSALEFVRDKYSNISQDFQFWRGQLGRYGLTGEGQTVQMATLSEGQRSRVVFAL 528
Query: 548 LAEGCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHG 727
LA P++LLLDEPTN LD+ TIDSLADAINEF GG+++VSHDFRL+ ++A++I+V ++
Sbjct: 529 LALEQPNVLLLDEPTNGLDIPTIDSLADAINEFNGGVVVVSHDFRLLDKIAQDIFVVENK 588
Query: 728 AVTKWPGDIYSYKTSLIKEI 787
T+W G I YK L K +
Sbjct: 589 TATRWDGSILQYKNKLAKNV 608
Score = 51.6 bits (122), Expect = 3e-06
Identities = 61/235 (25%), Positives = 101/235 (42%), Gaps = 29/235 (12%)
Frame = +2
Query: 146 IQVQNVSFKYGANKPLIYDNIDFGVDLD--TRVALVGPNGAGKSTLLKLIA--------- 292
I++ +VS + K LI D+ G++L+ R L+G NG GKST LK +A
Sbjct: 82 IKLSSVSLLFHG-KVLIQDS---GLELNYGRRYGLLGENGCGKSTFLKALATREYPIPEH 137
Query: 293 ------------SELEPTDGLIRRHSKCRIGRYHQHLHEILDLNSTALEWMMKSFPHIKE 436
SEL D ++ ++ + R + + + + E + + +
Sbjct: 138 IDIYLLDEPAEPSELSALDYVVTE-AQHELKRIEDLVEKTILEDGPESELLEPLYERMDS 196
Query: 437 KD----EMRKKLGRYGLTGGQQ--ICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNH 598
D E R + GL ++ + K +S G + R+ A P +LLLD+PT H
Sbjct: 197 LDPDTFESRAAIILIGLGFNKKTILKKTKDMSGGWKMRVALAKALFVKPTLLLLDDPTAH 256
Query: 599 LDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSY 763
LDLE L + + F+ L+LVSH + V + +T + G+ SY
Sbjct: 257 LDLEACVWLEEYLKRFDRTLVLVSHSQDFLNGVCTNMIDMRAQKLTAYGGNYDSY 311
>sp|P43535|GCN20_YEAST Protein GCN20
Length = 752
Score = 214 bits (546), Expect = 2e-55
Identities = 106/258 (41%), Positives = 170/258 (65%)
Frame = +2
Query: 17 ARQAQSKEKTLKKMVDGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKPLI 196
+++AQS+ K L+K+ + + ++K + F FP C ++ PP+IQ+Q+VSF Y N L+
Sbjct: 492 SQEAQSRIKKLEKLP---VLEPPEQDKTIDFKFPECDKLSPPIIQLQDVSFGYDENNLLL 548
Query: 197 YDNIDFGVDLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQHLHEI 376
D ++ V +D+R+ALVG NG GK+TLLK++ +L P G + R+ + RIG + QH +
Sbjct: 549 KD-VNLDVQMDSRIALVGANGCGKTTLLKIMMEQLRPLKGFVSRNPRLRIGYFTQHHVDS 607
Query: 377 LDLNSTALEWMMKSFPHIKEKDEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAE 556
+DL ++A++WM KSFP K +E R+ LG +G+TG + ++ LS GQ+ R+ FA L
Sbjct: 608 MDLTTSAVDWMSKSFPG-KTDEEYRRHLGSFGITGTLGLQKMQLLSGGQKSRVAFAALCL 666
Query: 557 GCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVT 736
PH+L+LDEP+NHLD +D+L +A+ F GG+L+VSHD +I V +EIWV + G V
Sbjct: 667 NNPHILVLDEPSNHLDTTGLDALVEALKNFNGGVLMVSHDISVIDSVCKEIWVSEQGTVK 726
Query: 737 KWPGDIYSYKTSLIKEIE 790
++ G IY Y+ +++ +
Sbjct: 727 RFEGTIYDYRDYILQSAD 744
Score = 56.6 bits (135), Expect = 9e-08
Identities = 72/263 (27%), Positives = 101/263 (38%), Gaps = 54/263 (20%)
Frame = +2
Query: 194 IYDNIDFGVDLDTRVALVGPNGAGKSTLLKLIAS-ELEPTDGLIRRHSKCRI-GRYHQHL 367
I N + R LVG NG GKSTLL+ ++ EL + H + + G + L
Sbjct: 214 ILSNAQLTLSFGHRYGLVGQNGIGKSTLLRALSRRELNVPKHVSILHVEQELRGDDTKAL 273
Query: 368 HEILDLN---STALEWMMKSFPHIKEKDEMR----------KKLGR-------------- 466
+LD + L K +KE D +R KKL
Sbjct: 274 QSVLDADVWRKQLLSEEAKINERLKEMDVLRQEFEEDSLEVKKLDNEREDLDNHLIQISD 333
Query: 467 ------------------YGL---TGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLD 583
YGL T QQ P S S G R R+ A P +LLLD
Sbjct: 334 KLVDMESDKAEARAASILYGLGFSTEAQQQ-PTNSFSGGWRMRLSLARALFCQPDLLLLD 392
Query: 584 EPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGD---- 751
EP+N LD+ +I LA+ + + +L VSHD + VA +I + + + G
Sbjct: 393 EPSNMLDVPSIAYLAEYLKTYPNTVLTVSHDRAFLNEVATDIIYQHNERLDYYRGQDFDT 452
Query: 752 IYSYKTSLIKEIEREHTRMMTER 820
Y+ K K +RE+ M R
Sbjct: 453 FYTTKEERRKNAQREYDNQMVYR 475
>sp|Q6MG08|ABCF1_RAT ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50)
Length = 839
Score = 189 bits (479), Expect = 1e-47
Identities = 97/233 (41%), Positives = 153/233 (65%)
Frame = +2
Query: 89 REKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGK 268
RE + F+FP + PPV+ + V+F Y KPL + N+DFG+D+D+R+ +VGPNG GK
Sbjct: 600 REYTVRFTFPDPPPLSPPVLGLHGVTFGYEGQKPL-FKNLDFGIDMDSRICIVGPNGVGK 658
Query: 269 STLLKLIASELEPTDGLIRRHSKCRIGRYHQHLHEILDLNSTALEWMMKSFPHIKEKDEM 448
STLL L+ +L PT+G +R++ + +IG ++Q E L + T E++ + F ++ +D
Sbjct: 659 STLLLLLTGKLTPTNGEMRKNHRLKIGFFNQQYAEQLHMEETPTEYLQRGF-NLPYQDA- 716
Query: 449 RKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDSLA 628
RK LGR+GL I LS GQ+ R++FA LA P +L+LDEPTN+LD+E+ID+L
Sbjct: 717 RKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALG 776
Query: 629 DAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYKTSLIKEI 787
+AINE++G +++VSHD RLI ++WV + +V++ GD YK +++ +
Sbjct: 777 EAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFDDYKREVLEAL 829
Score = 74.7 bits (182), Expect = 3e-13
Identities = 78/309 (25%), Positives = 132/309 (42%), Gaps = 45/309 (14%)
Frame = +2
Query: 17 ARQAQSKEKTLKKMVDGGLTQKVIREKNLV---FSFPSCGEIPPPVIQVQNVS------F 169
A ++ ++K LKK +D + ++ N FS S E+ ++N S F
Sbjct: 245 AHLSKKEKKKLKKQMDYERQVESLKAANAAENDFSV-SQAEVSSRQAMLENASDIKLEKF 303
Query: 170 KYGANKPLIYDNIDFGVDLDTRVALVGPNGAGKSTLLK---------------------L 286
A+ ++ N D + R LVGPNG GK+TLLK +
Sbjct: 304 SISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQEV 363
Query: 287 IASELEPTDGLIRRHSK-CRIGRYHQHLHEILDL-NSTALEWMMKSFPHIKE------KD 442
+A E ++R +K R+ + L L+ + TA E + K + ++ +
Sbjct: 364 VADETPAVQAVLRADTKRLRLLEEEKRLQGQLEQGDDTAAEKLEKVYEELRATGAAAAEA 423
Query: 443 EMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDS 622
+ R+ L G Q P + S G R R+ A P +L+LDEPTNHLDL +
Sbjct: 424 KARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIW 483
Query: 623 LADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYK-------TSLIK 781
L + + + LL+VSHD + V +I D + + G+ ++K L+K
Sbjct: 484 LNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDTQRLHYYRGNYMTFKKMYQQKQKELLK 543
Query: 782 EIEREHTRM 808
+ E++ ++
Sbjct: 544 QYEKQEKKL 552
>sp|Q6P542|ABCF1_MOUSE ATP-binding cassette sub-family F member 1
Length = 837
Score = 187 bits (476), Expect = 3e-47
Identities = 96/233 (41%), Positives = 153/233 (65%)
Frame = +2
Query: 89 REKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGK 268
+E + F+FP + PPV+ + V+F Y KPL + N+DFG+D+D+R+ +VGPNG GK
Sbjct: 598 KEYTVRFTFPDPPPLSPPVLGLHGVTFGYEGQKPL-FKNLDFGIDMDSRICIVGPNGVGK 656
Query: 269 STLLKLIASELEPTDGLIRRHSKCRIGRYHQHLHEILDLNSTALEWMMKSFPHIKEKDEM 448
STLL L+ +L PT+G +R++ + +IG ++Q E L + T E++ +SF ++ +D
Sbjct: 657 STLLLLLTGKLTPTNGEMRKNHRLKIGFFNQQYAEQLHMEETPTEYLQRSF-NLPYQDA- 714
Query: 449 RKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDSLA 628
RK LGR+GL I LS GQ+ R++FA LA P +L+LDEPTN+LD+E+ID+L
Sbjct: 715 RKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALG 774
Query: 629 DAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYKTSLIKEI 787
+AIN+++G +++VSHD RLI ++WV + V++ GD YK +++ +
Sbjct: 775 EAINDYKGAVIVVSHDARLITETNCQLWVVEEQGVSQIDGDFDDYKREVLEAL 827
Score = 74.7 bits (182), Expect = 3e-13
Identities = 78/309 (25%), Positives = 132/309 (42%), Gaps = 45/309 (14%)
Frame = +2
Query: 17 ARQAQSKEKTLKKMVDGGLTQKVIREKNLV---FSFPSCGEIPPPVIQVQNVS------F 169
A ++ ++K LKK +D + ++ N FS S E+ ++N S F
Sbjct: 243 ANLSKKEKKKLKKQMDYERQVESLKAANAAENDFSV-SQAEVSSRQAMLENASDIKLEKF 301
Query: 170 KYGANKPLIYDNIDFGVDLDTRVALVGPNGAGKSTLLK---------------------L 286
A+ ++ N D + R LVGPNG GK+TLLK +
Sbjct: 302 SISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQEV 361
Query: 287 IASELEPTDGLIRRHSK-CRIGRYHQHLHEILDL-NSTALEWMMKSFPHIKE------KD 442
+A E ++R +K R+ + L L+ + TA E + K + ++ +
Sbjct: 362 VADETPAVQAVLRADTKRLRLLEEERRLQGQLEQGDDTAAEKLEKVYEELRATGAAAAEA 421
Query: 443 EMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDS 622
+ R+ L G Q P + S G R R+ A P +L+LDEPTNHLDL +
Sbjct: 422 KARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIW 481
Query: 623 LADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYK-------TSLIK 781
L + + + LL+VSHD + V +I D + + G+ ++K L+K
Sbjct: 482 LNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDTQRLHYYRGNYMTFKKMYQQKQKELLK 541
Query: 782 EIEREHTRM 808
+ E++ ++
Sbjct: 542 QYEKQEKKL 550
>sp|Q8NE71|ABCF1_HUMAN ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50)
(TNF-alpha-stimulated ABC protein)
Length = 845
Score = 187 bits (474), Expect = 4e-47
Identities = 96/233 (41%), Positives = 152/233 (65%)
Frame = +2
Query: 89 REKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGK 268
+E + F+FP + PPV+ + V+F Y KPL + N+DFG+D+D+R+ +VGPNG GK
Sbjct: 606 KEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKPL-FKNLDFGIDMDSRICIVGPNGVGK 664
Query: 269 STLLKLIASELEPTDGLIRRHSKCRIGRYHQHLHEILDLNSTALEWMMKSFPHIKEKDEM 448
STLL L+ +L PT G +R++ + +IG ++Q E L + T E++ + F ++ +D
Sbjct: 665 STLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGF-NLPYQDA- 722
Query: 449 RKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDSLA 628
RK LGR+GL I LS GQ+ R++FA LA P +L+LDEPTN+LD+E+ID+L
Sbjct: 723 RKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALG 782
Query: 629 DAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYKTSLIKEI 787
+AINE++G +++VSHD RLI ++WV + +V++ GD YK +++ +
Sbjct: 783 EAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYKREVLEAL 835
Score = 70.5 bits (171), Expect = 6e-12
Identities = 64/250 (25%), Positives = 108/250 (43%), Gaps = 36/250 (14%)
Frame = +2
Query: 167 FKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGKSTLLK--------------------- 283
F A+ ++ N D + R LVGPNG GK+TLLK
Sbjct: 309 FSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQE 368
Query: 284 LIASELEPTDGLIRRHSK-CRIGRYHQHLHEILDL-NSTALEWMMKSFPHIKE------K 439
++A E ++R +K ++ + L L+ + TA E + K + ++ +
Sbjct: 369 VVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELRATGAAAAE 428
Query: 440 DEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETID 619
+ R+ L G Q P + S G R R+ A P +L+LDEPTNHLDL +
Sbjct: 429 AKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVI 488
Query: 620 SLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYK-------TSLI 778
L + + + LL+VSHD + V +I D + + G+ ++K L+
Sbjct: 489 WLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQKQKELL 548
Query: 779 KEIEREHTRM 808
K+ E++ ++
Sbjct: 549 KQYEKQEKKL 558
>sp|Q7YR37|ABCF1_PANTR ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50)
Length = 807
Score = 187 bits (474), Expect = 4e-47
Identities = 96/233 (41%), Positives = 152/233 (65%)
Frame = +2
Query: 89 REKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGK 268
+E + F+FP + PPV+ + V+F Y KPL + N+DFG+D+D+R+ +VGPNG GK
Sbjct: 568 KEYTVRFTFPDPPPLSPPVLGLHGVTFGYEGQKPL-FKNLDFGIDMDSRICIVGPNGVGK 626
Query: 269 STLLKLIASELEPTDGLIRRHSKCRIGRYHQHLHEILDLNSTALEWMMKSFPHIKEKDEM 448
STLL L+ +L PT G +R++ + +IG ++Q E L + T E++ + F ++ +D
Sbjct: 627 STLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGF-NLPYQDA- 684
Query: 449 RKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDSLA 628
RK LGR+GL I LS GQ+ R++FA LA P +L+LDEPTN+LD+E+ID+L
Sbjct: 685 RKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALG 744
Query: 629 DAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYKTSLIKEI 787
+AINE++G +++VSHD RLI ++WV + +V++ GD YK +++ +
Sbjct: 745 EAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYKREVLEAL 797
Score = 70.9 bits (172), Expect = 4e-12
Identities = 64/250 (25%), Positives = 108/250 (43%), Gaps = 36/250 (14%)
Frame = +2
Query: 167 FKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGKSTLLK--------------------- 283
F A+ ++ N D + R LVGPNG GK+TLLK
Sbjct: 271 FSISAHGKELFVNADLYIVASRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQE 330
Query: 284 LIASELEPTDGLIRRHSK-CRIGRYHQHLHEILDL-NSTALEWMMKSFPHIKE------K 439
++A E ++R +K ++ + L L+ + TA E + K + ++ +
Sbjct: 331 VVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELRATGAAAAE 390
Query: 440 DEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETID 619
+ R+ L G Q P + S G R R+ A P +L+LDEPTNHLDL +
Sbjct: 391 AKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVI 450
Query: 620 SLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYK-------TSLI 778
L + + + LL+VSHD + V +I D + + G+ ++K L+
Sbjct: 451 WLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQKQKELL 510
Query: 779 KEIEREHTRM 808
K+ E++ ++
Sbjct: 511 KQYEKQEKKL 520
>sp|Q767L0|ABCF1_PIG ATP-binding cassette sub-family F member 1
Length = 807
Score = 186 bits (472), Expect = 7e-47
Identities = 96/233 (41%), Positives = 152/233 (65%)
Frame = +2
Query: 89 REKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGK 268
+E + F+FP + PPV+ + V+F Y KPL + N+DFG+D+D+R+ +VGPNG GK
Sbjct: 568 KEYTVRFTFPDPPPLSPPVLGLHGVTFGYEGQKPL-FKNLDFGIDMDSRICIVGPNGVGK 626
Query: 269 STLLKLIASELEPTDGLIRRHSKCRIGRYHQHLHEILDLNSTALEWMMKSFPHIKEKDEM 448
STLL L+ +L PT G +R++ + +IG ++Q E L + T E++ + F ++ +D
Sbjct: 627 STLLLLLTGKLTPTRGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGF-NLPYQDA- 684
Query: 449 RKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDSLA 628
RK LGR+GL I LS GQ+ R++FA LA P +L+LDEPTN+LD+E+ID+L
Sbjct: 685 RKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALG 744
Query: 629 DAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYKTSLIKEI 787
+AINE++G +++VSHD RLI ++WV + +V++ GD YK +++ +
Sbjct: 745 EAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFDDYKREVLEAL 797
Score = 69.3 bits (168), Expect = 1e-11
Identities = 63/250 (25%), Positives = 108/250 (43%), Gaps = 36/250 (14%)
Frame = +2
Query: 167 FKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGKSTLLK--------------------- 283
F A+ ++ N D + R LVGPNG GK+TLLK
Sbjct: 271 FSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQE 330
Query: 284 LIASELEPTDGLIRRHSK-CRIGRYHQHLHEILDL-NSTALEWMMKSFPHIKE------K 439
++A E ++R +K ++ + L L+ + TA + + K + ++ +
Sbjct: 331 VVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAADRLEKVYEELRATGAAAAE 390
Query: 440 DEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETID 619
+ R+ L G Q P + S G R R+ A P +L+LDEPTNHLDL +
Sbjct: 391 AKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVI 450
Query: 620 SLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYK-------TSLI 778
L + + + LL+VSHD + V +I D + + G+ ++K L+
Sbjct: 451 WLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQKQKELL 510
Query: 779 KEIEREHTRM 808
K+ E++ ++
Sbjct: 511 KQYEKQEKKL 520
>sp|P63390|YHES_ECO57 Hypothetical ABC transporter ATP-binding protein yheS
sp|P63389|YHES_ECOLI Hypothetical ABC transporter ATP-binding protein yheS
Length = 637
Score = 142 bits (359), Expect = 9e-34
Identities = 85/250 (34%), Positives = 142/250 (56%)
Frame = +2
Query: 17 ARQAQSKEKTLKKMVDGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKPLI 196
A+QAQS+ K L++M L + FSF + +P P+++++ VS YG +I
Sbjct: 273 AKQAQSRIKMLERME---LIAPAHVDNPFRFSFRAPESLPNPLLKMEKVSAGYGDR--II 327
Query: 197 YDNIDFGVDLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQHLHEI 376
D+I + +R+ L+G NGAGKSTL+KL+A EL P G I ++G + QH E
Sbjct: 328 LDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAKGIKLGYFAQHQLEY 387
Query: 377 LDLNSTALEWMMKSFPHIKEKDEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAE 556
L + + ++ + + P E+ ++R LG +G G + + S G++ R++ A +
Sbjct: 388 LRADESPIQHLARLAPQELEQ-KLRDYLGGFGFQGDKVTEETRRFSGGEKARLVLALIVW 446
Query: 557 GCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVT 736
P++LLLDEPTNHLDL+ +L +A+ EFEG L++VSHD L+ +++++ V
Sbjct: 447 QRPNLLLLDEPTNHLDLDMRQALTEALIEFEGALVVVSHDRHLLRSTTDDLYLVHDRKVE 506
Query: 737 KWPGDIYSYK 766
+ GD+ Y+
Sbjct: 507 PFDGDLEDYQ 516
Score = 67.0 bits (162), Expect = 6e-11
Identities = 54/224 (24%), Positives = 94/224 (41%), Gaps = 32/224 (14%)
Frame = +2
Query: 191 LIYDNIDFGVDLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQHLH 370
++ DN ++ +V LVG NG GKSTLL L+ +E+ G ++ +Q
Sbjct: 15 VLLDNATATINPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGSWQLAWVNQ--- 71
Query: 371 EILDLNSTALEWMMKSFPHIKE--------------------------------KDEMRK 454
E L ALE+++ ++ +
Sbjct: 72 ETPALPQAALEYVIDGDREYRQLEAQLHDANERNDGHAIATIHGKLDAIDAWSIRSRAAS 131
Query: 455 KLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDSLADA 634
L G + Q P+ S G R R+ A +LLLDEPTNHLDL+ + L
Sbjct: 132 LLHGLGFSNEQLERPVSDFSGGWRMRLNLAQALICRSDLLLLDEPTNHLDLDAVIWLEKW 191
Query: 635 INEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYK 766
+ ++G L+L+SHD + + ++I + ++ ++ G+ S++
Sbjct: 192 LKSYQGTLILISHDRDFLDPIVDKIIHIEQQSMFEYTGNYSSFE 235
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,136,531
Number of Sequences: 369166
Number of extensions: 1992753
Number of successful extensions: 10696
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 8834
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10182
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8646143400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)