Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_A04
(723 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q6J5K9|ARMI_DROME Probable RNA helicase armi (Armitage p... 144 2e-34
sp|Q9BXT6|M10L1_HUMAN Putative helicase Mov10l1 (Moloney le... 135 1e-31
sp|Q99MV5|M10L1_MOUSE Putative helicase Mov10l1 (Moloney le... 131 2e-30
sp|Q9HCE1|MOV10_HUMAN Putative helicase MOV-10 (Moloney leu... 99 9e-21
sp|P23249|MOV10_MOUSE Putative helicase MOV-10 (Moloney leu... 96 7e-20
sp|Q8GYD9|SDE3_ARATH Probable RNA helicase SDE3 (Silencing ... 91 2e-18
sp|P34243|YKB7_YEAST Hypothetical 78.3 kDa protein in RAM2-... 59 2e-08
sp|Q9HEH1|RENT1_NEUCR Regulator of nonsense transcripts 1 h... 56 9e-08
sp|Q57568|Y104_METJA Hypothetical ATP-binding protein MJ0104 56 9e-08
sp|Q60560|SMBP2_MESAU DNA-binding protein SMUBP-2 (Immunogl... 56 1e-07
>sp|Q6J5K9|ARMI_DROME Probable RNA helicase armi (Armitage protein)
Length = 1274
Score = 144 bits (364), Expect = 2e-34
Identities = 76/217 (35%), Positives = 127/217 (58%), Gaps = 2/217 (0%)
Frame = +3
Query: 6 GTIEDILCDLIFVKFHETLHSNYTNEECTVTFGHSRLPFRRIHLGIEVGCGILGDRILFP 185
G I +L D I +KFH + Y E+ + F SR FR+ H I G++G+ LFP
Sbjct: 691 GIIHKVLFDRILLKFHSSFQEKYNGEDYRLEFYFSRYSFRKQHHAISKIVGVMGEDFLFP 750
Query: 186 EKIEMKPSQCVRLSRSGCNEISAINFVKVEAYNML--QLKFYNESLNELQRVAVLRILHG 359
K+ + + + + ++K + + +L++YN+SLN +Q+ AV IL G
Sbjct: 751 SKVTKRENPQLDV------------YMKDDDMYLYDSKLEWYNQSLNSIQKRAVFNILRG 798
Query: 360 YSRPLPYILFGPPGTGKTVTLVEAILQVYKNIPSSRILLCAPSNSAADLLCLRLDESVII 539
+ +PY+LFGPPG+GKT+TL+E +LQ+ +N+P +RIL+ PSNS+ADL+ RL +S +
Sbjct: 799 EAENIPYVLFGPPGSGKTMTLIETLLQLVRNLPGARILVGTPSNSSADLVTKRLIDSKAL 858
Query: 540 ESGEMVRMNAFRRTILSEMSDKEPIPPRVLPYCKSID 650
G+ +R+ ++ + +K+ IPP ++ YC + D
Sbjct: 859 LQGDFIRLVSYNQV------EKDLIPPEIMSYCATSD 889
>sp|Q9BXT6|M10L1_HUMAN Putative helicase Mov10l1 (Moloney leukemia virus 10-like protein 1)
(MOV10-like 1)
Length = 1211
Score = 135 bits (340), Expect = 1e-31
Identities = 89/248 (35%), Positives = 127/248 (51%), Gaps = 41/248 (16%)
Frame = +3
Query: 36 IFVKFHETLHSNYTNEECTVTFGHSRLPFRRIHLGIEVGCGILGDRILFPEKIEMKPSQC 215
+ +K + Y E V F ++R RR H +E LG ++LFPE+I ++ Q
Sbjct: 612 VTLKINPEFEQAYNFEPMDVEFTYNRTTSRRCHFALEHVIH-LGVKVLFPEEIILQSPQV 670
Query: 216 V--------------------------------RLSRSGCNEISAINFVKVEAYNML--- 290
R G ++ + E + +
Sbjct: 671 TGNWNHAQDTKSSGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFTAEMSDWVDEI 730
Query: 291 ------QLKFYNESLNELQRVAVLRILHGYSRPLPYILFGPPGTGKTVTLVEAILQVYKN 452
+++F+N LNE Q++AV RIL G RPLPYILFGPPGTGKTVT++EA+LQV+
Sbjct: 731 QTPKARKMEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHFA 790
Query: 453 IPSSRILLCAPSNSAADLLCLRLDESVIIESGEMVRMNAFRRTILSEMSDKEPIPPRVLP 632
+P SRIL+CAPSNSAADL+CLRL ES +++ MVR+NA R +E + V P
Sbjct: 791 LPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCRF-------EEIVIDAVKP 843
Query: 633 YCKSIDDV 656
YC+ +D+
Sbjct: 844 YCRDGEDI 851
>sp|Q99MV5|M10L1_MOUSE Putative helicase Mov10l1 (Moloney leukemia virus 10-like protein 1)
(MOV10-like 1) (Cardiac helicase activated by MEF2
protein) (Cardiac-specific RNA helicase)
Length = 1187
Score = 131 bits (330), Expect = 2e-30
Identities = 68/120 (56%), Positives = 87/120 (72%)
Frame = +3
Query: 297 KFYNESLNELQRVAVLRILHGYSRPLPYILFGPPGTGKTVTLVEAILQVYKNIPSSRILL 476
+F+N LNE Q++AV RIL G RPLPYILFGPPGTGKTVT++EA+LQV+ +P SRIL+
Sbjct: 741 EFFNPVLNENQKLAVRRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHYALPDSRILV 800
Query: 477 CAPSNSAADLLCLRLDESVIIESGEMVRMNAFRRTILSEMSDKEPIPPRVLPYCKSIDDV 656
CAPSNSAADL+CLRL ES + + MVR+NA R +E I + PYC+ +D+
Sbjct: 801 CAPSNSAADLVCLRLHESKVPKPAAMVRVNATCRF-------EETIIDAIKPYCRDGEDI 853
Score = 30.4 bits (67), Expect = 5.0
Identities = 20/69 (28%), Positives = 34/69 (49%)
Frame = +3
Query: 6 GTIEDILCDLIFVKFHETLHSNYTNEECTVTFGHSRLPFRRIHLGIEVGCGILGDRILFP 185
G + +I + + +K + Y E V F ++R RR H +E LG ++LFP
Sbjct: 542 GYVMEIHEEDVTLKLNPGFEQMYNFEPMDVEFTYNRTTSRRCHYALEQVIH-LGVKVLFP 600
Query: 186 EKIEMKPSQ 212
E+I ++ Q
Sbjct: 601 EEIILQSPQ 609
>sp|Q9HCE1|MOV10_HUMAN Putative helicase MOV-10 (Moloney leukemia virus 10 protein)
Length = 1003
Score = 99.4 bits (246), Expect = 9e-21
Identities = 73/214 (34%), Positives = 102/214 (47%), Gaps = 3/214 (1%)
Frame = +3
Query: 6 GTIEDILCDLIFVKFHETLHSNYTNE-ECTVTFGHSRLPFRRIHLGIEVGCGILGDRILF 182
G + + D + + F +L S + + V F +R P R H +E + G +L+
Sbjct: 415 GFVHKVELDRVKLSFSMSLLSRFVDGLTFKVNFTFNRQPLRVQHRALE----LTGRWLLW 470
Query: 183 PEKIEMKPSQCVRLSRSGCNEISAINFVKVEAYNMLQLKFYNESL--NELQRVAVLRILH 356
P + P L ++LK Y+ SL N Q A+ I+
Sbjct: 471 PMLFPVAPRDVPLLPSD------------------VKLKLYDRSLESNPEQLQAMRHIVT 512
Query: 357 GYSRPLPYILFGPPGTGKTVTLVEAILQVYKNIPSSRILLCAPSNSAADLLCLRLDESVI 536
G +RP PYI+FGPPGTGKTVTLVEAI QV K++P + IL CAPSNS ADLLC RL
Sbjct: 513 GTTRPAPYIIFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRL----- 567
Query: 537 IESGEMVRMNAFRRTILSEMSDKEPIPPRVLPYC 638
V + + +L+ D +P + P C
Sbjct: 568 -----RVHLPSSIYRLLAPSRDIRMVPEDIKPCC 596
>sp|P23249|MOV10_MOUSE Putative helicase MOV-10 (Moloney leukemia virus 10 protein)
Length = 1004
Score = 96.3 bits (238), Expect = 7e-20
Identities = 68/175 (38%), Positives = 92/175 (52%), Gaps = 3/175 (1%)
Frame = +3
Query: 6 GTIEDILCDLIFVKFHETLHSNYTNE-ECTVTFGHSRLPFRRIHLGIEVGCGILGDRILF 182
G + + D + + F +L S + + V F +R P R H +E + G +L+
Sbjct: 416 GFVHKVELDRVKLSFSTSLLSRFVDGLTFKVNFTFNRQPLRVQHRALE----LTGRWVLW 471
Query: 183 PEKIEMKPSQCVRLSRSGCNEISAINFVKVEAYNMLQLKFYNESL--NELQRVAVLRILH 356
P + S+ V L S ++ K Y+ SL N Q A+ I+
Sbjct: 472 PMLFPVA-SRGVSLLPSD-----------------VKFKLYDRSLESNPEQLQAMKHIVR 513
Query: 357 GYSRPLPYILFGPPGTGKTVTLVEAILQVYKNIPSSRILLCAPSNSAADLLCLRL 521
G +RP PYI+FGPPGTGKTVTLVEAI QV K++P + IL CAPSNS ADLLC RL
Sbjct: 514 GTTRPAPYIIFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRL 568
>sp|Q8GYD9|SDE3_ARATH Probable RNA helicase SDE3 (Silencing defective protein 3)
Length = 1002
Score = 91.3 bits (225), Expect = 2e-18
Identities = 70/217 (32%), Positives = 105/217 (48%), Gaps = 6/217 (2%)
Frame = +3
Query: 6 GTIEDILCDLIFVKFHETLHSNYT-NEECTVTFGHSRLPFRRIHLGIEVGCGILGDRILF 182
G + + D + +KF H +T V F ++R+ RR++ ++ +L LF
Sbjct: 317 GFVHRVEADEVHMKFASEFHQRHTAGSVYNVRFTYNRINTRRLYQAVDAA-EMLDPNFLF 375
Query: 183 PEKIEMKPSQCVRLSRSGCNEISAINFVKVEAYNMLQLKFYNESLNELQRVAVLRILHGY 362
P SG I FV + + +LN Q ++ +L
Sbjct: 376 PSL------------HSGKRMIKTKPFVPI-----------SPALNAEQICSIEMVLGCK 412
Query: 363 SRPLPYILFGPPGTGKTVTLVEAILQVYKNIPSSRILLCAPSNSAAD-----LLCLRLDE 527
P PY++ GPPGTGKT+TLVEAI+Q+Y ++R+L+CAPSNSAAD LLCL E
Sbjct: 413 GAP-PYVIHGPPGTGKTMTLVEAIVQLYTTQRNARVLVCAPSNSAADHILEKLLCL---E 468
Query: 528 SVIIESGEMVRMNAFRRTILSEMSDKEPIPPRVLPYC 638
V I+ E+ R+NA R+ E I P ++ +C
Sbjct: 469 GVRIKDNEIFRLNAATRSY-------EEIKPEIIRFC 498
>sp|P34243|YKB7_YEAST Hypothetical 78.3 kDa protein in RAM2-ATP7 intergenic region
Length = 683
Score = 58.5 bits (140), Expect = 2e-08
Identities = 38/110 (34%), Positives = 59/110 (53%), Gaps = 5/110 (4%)
Frame = +3
Query: 300 FYNESLNELQRVAVLRILHGYSRPLPYILFGPPGTGKTVTLVEAILQVYKNIPSSRILLC 479
F N +LN+ Q+ A+ ++ I+ GPPGTGKT TL+E I Q+ P RIL+C
Sbjct: 203 FLNPNLNDSQKTAINFAINNDLT----IIHGPPGTGKTFTLIELIQQLLIKNPEERILIC 258
Query: 480 APSNSAADLLCLRL----DESVIIESGEMVR-MNAFRRTILSEMSDKEPI 614
PSN + D + RL ++++ G R +++ +R L +S K I
Sbjct: 259 GPSNISVDTILERLTPLVPNNLLLRIGHPARLLDSNKRHSLDILSKKNTI 308
>sp|Q9HEH1|RENT1_NEUCR Regulator of nonsense transcripts 1 homolog
Length = 1093
Score = 56.2 bits (134), Expect = 9e-08
Identities = 38/94 (40%), Positives = 52/94 (55%)
Frame = +3
Query: 297 KFYNESLNELQRVAVLRILHGYSRPLPYILFGPPGTGKTVTLVEAILQVYKNIPSSRILL 476
KF+ L EL + I S PL I GPPGTGKTVT I + K + +S++L+
Sbjct: 447 KFHVPGLPELNASQIAAIKQVLSNPLSLIQ-GPPGTGKTVTSATIIYHLAK-MSNSQVLV 504
Query: 477 CAPSNSAADLLCLRLDESVIIESGEMVRMNAFRR 578
CAPSN A D LC R+ + + ++VR+ A R
Sbjct: 505 CAPSNVAVDQLCERIHRTGL----KVVRLTAKSR 534
>sp|Q57568|Y104_METJA Hypothetical ATP-binding protein MJ0104
Length = 663
Score = 56.2 bits (134), Expect = 9e-08
Identities = 33/72 (45%), Positives = 49/72 (68%)
Frame = +3
Query: 288 LQLKFYNESLNELQRVAVLRILHGYSRPLPYILFGPPGTGKTVTLVEAILQVYKNIPSSR 467
++L+FY+++LNE Q++AV + + SR L Y++ GPPGTGKT T+ E I+Q K +
Sbjct: 176 IKLEFYDKNLNESQKLAVKKAV--LSRDL-YLIHGPPGTGKTRTITEVIVQEVK-FNKHK 231
Query: 468 ILLCAPSNSAAD 503
+L A SN AAD
Sbjct: 232 VLATADSNIAAD 243
>sp|Q60560|SMBP2_MESAU DNA-binding protein SMUBP-2 (Immunoglobulin mu-binding protein 2)
(SMUBP-2) (Insulin II gene enhancer-binding protein)
(RIPE3B-binding complex 3B2 p110 subunit) (RIP-1)
Length = 989
Score = 55.8 bits (133), Expect = 1e-07
Identities = 36/74 (48%), Positives = 44/74 (59%)
Frame = +3
Query: 300 FYNESLNELQRVAVLRILHGYSRPLPYILFGPPGTGKTVTLVEAILQVYKNIPSSRILLC 479
FYN +L+ Q+ AV L ++ I+ GPPGTGKT T+VE ILQ K +IL C
Sbjct: 186 FYNTALDPSQKEAVSFAL---AQKEVAIIHGPPGTGKTTTVVEIILQAVKQ--GLKILCC 240
Query: 480 APSNSAADLLCLRL 521
APSN A D L RL
Sbjct: 241 APSNVAVDNLVERL 254
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,577,465
Number of Sequences: 369166
Number of extensions: 1531557
Number of successful extensions: 6010
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5724
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5978
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6462248555
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)