Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_P03
(465 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P81178|ALDH2_MESAU Aldehyde dehydrogenase, mitochondrial... 183 1e-46
sp|P11884|ALDH2_RAT Aldehyde dehydrogenase, mitochondrial p... 183 2e-46
sp|P12762|ALDH2_HORSE Aldehyde dehydrogenase, mitochondrial... 181 5e-46
sp|P05091|ALDH2_HUMAN Aldehyde dehydrogenase, mitochondrial... 181 7e-46
sp|Q62148|AL1A2_MOUSE Retinal dehydrogenase 2 (RalDH2) (RAL... 181 7e-46
sp|P47738|ALDH2_MOUSE Aldehyde dehydrogenase, mitochondrial... 181 7e-46
sp|Q63639|AL1A2_RAT Retinal dehydrogenase 2 (RalDH2) (RALDH... 181 7e-46
sp|P27463|AL1A1_CHICK Retinal dehydrogenase 1 (RalDH1) (RAL... 181 9e-46
sp|P20000|ALDH2_BOVIN Aldehyde dehydrogenase, mitochondrial... 180 2e-45
sp|P30837|AL1B1_HUMAN Aldehyde dehydrogenase X, mitochondri... 179 4e-45
>sp|P81178|ALDH2_MESAU Aldehyde dehydrogenase, mitochondrial (ALDH class 2) (ALDH1)
(ALDH-E2)
Length = 500
Score = 183 bits (465), Expect = 1e-46
Identities = 88/134 (65%), Positives = 104/134 (77%)
Frame = +3
Query: 3 LVTGGNRIGNVGYFIQPTVFGDVKDNMRIAKEEIFGPVQSVFKFNTMEEVIERANNSDYG 182
L+ GG + GYFIQPTVFGDVKD M IAKEEIFGPV + KF T+EEV+ RANNS YG
Sbjct: 367 LLCGGGAAADRGYFIQPTVFGDVKDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSKYG 426
Query: 183 LGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVTAPFGGFKQSGVGRELGCYGLEPYI 362
L A VFT D++KA ++QAL+AG+VW+NCYDV +PFGG+K SG GRELG YGL+ Y
Sbjct: 427 LAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYT 486
Query: 363 EVKGVTIAIPQKNS 404
EVK VTI +PQKNS
Sbjct: 487 EVKTVTIKVPQKNS 500
>sp|P11884|ALDH2_RAT Aldehyde dehydrogenase, mitochondrial precursor (ALDH class 2)
(ALDH1) (ALDH-E2)
Length = 519
Score = 183 bits (464), Expect = 2e-46
Identities = 87/134 (64%), Positives = 104/134 (77%)
Frame = +3
Query: 3 LVTGGNRIGNVGYFIQPTVFGDVKDNMRIAKEEIFGPVQSVFKFNTMEEVIERANNSDYG 182
L+ GG + GYFIQPTVFGDVKD M IAKEEIFGPV + KF T+EEV+ RANNS YG
Sbjct: 386 LLCGGGAAADRGYFIQPTVFGDVKDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSKYG 445
Query: 183 LGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVTAPFGGFKQSGVGRELGCYGLEPYI 362
L A VFT D++KA ++QAL+AG+VW+NCYDV +PFGG+K SG GRELG YGL+ Y
Sbjct: 446 LAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYT 505
Query: 363 EVKGVTIAIPQKNS 404
EVK VT+ +PQKNS
Sbjct: 506 EVKTVTVKVPQKNS 519
>sp|P12762|ALDH2_HORSE Aldehyde dehydrogenase, mitochondrial (ALDH class 2) (ALDHI)
(ALDH-E2)
Length = 500
Score = 181 bits (460), Expect = 5e-46
Identities = 87/134 (64%), Positives = 104/134 (77%)
Frame = +3
Query: 3 LVTGGNRIGNVGYFIQPTVFGDVKDNMRIAKEEIFGPVQSVFKFNTMEEVIERANNSDYG 182
L+ GG + GYFIQPTVFGDV+D M IAKEEIFGPV + KF T+EEV+ RANNS YG
Sbjct: 367 LLCGGGAAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSKYG 426
Query: 183 LGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVTAPFGGFKQSGVGRELGCYGLEPYI 362
L A VFT D++KA ++QAL+AG+VW+NCYDV +PFGG+K SG GRELG YGL+ Y
Sbjct: 427 LAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGNGRELGEYGLQAYT 486
Query: 363 EVKGVTIAIPQKNS 404
EVK VTI +PQKNS
Sbjct: 487 EVKTVTIKVPQKNS 500
>sp|P05091|ALDH2_HUMAN Aldehyde dehydrogenase, mitochondrial precursor (ALDH class 2)
(ALDHI) (ALDH-E2)
Length = 517
Score = 181 bits (459), Expect = 7e-46
Identities = 87/134 (64%), Positives = 104/134 (77%)
Frame = +3
Query: 3 LVTGGNRIGNVGYFIQPTVFGDVKDNMRIAKEEIFGPVQSVFKFNTMEEVIERANNSDYG 182
L+ GG + GYFIQPTVFGDV+D M IAKEEIFGPV + KF T+EEV+ RANNS YG
Sbjct: 384 LLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYG 443
Query: 183 LGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVTAPFGGFKQSGVGRELGCYGLEPYI 362
L A VFT D++KA ++QAL+AG+VWVNCYDV +PFGG+K SG GRELG YGL+ Y
Sbjct: 444 LAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYT 503
Query: 363 EVKGVTIAIPQKNS 404
EVK VT+ +PQKNS
Sbjct: 504 EVKTVTVKVPQKNS 517
>sp|Q62148|AL1A2_MOUSE Retinal dehydrogenase 2 (RalDH2) (RALDH 2) (RALDH(II))
(Retinaldehyde-specific dehydrogenase type 2) (Aldehyde
dehydrogenase family 1 member A2)
Length = 499
Score = 181 bits (459), Expect = 7e-46
Identities = 85/134 (63%), Positives = 107/134 (79%)
Frame = +3
Query: 3 LVTGGNRIGNVGYFIQPTVFGDVKDNMRIAKEEIFGPVQSVFKFNTMEEVIERANNSDYG 182
L GG +G G+FI+PTVF +V D+MRIAKEEIFGPVQ + +F TM+EVIERANNSD+G
Sbjct: 366 LECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFG 425
Query: 183 LGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVTAPFGGFKQSGVGRELGCYGLEPYI 362
L A VFT+DINKA+M++ A++AG+VW+NCY+ +PFGGFK SG GRE+G +GL Y
Sbjct: 426 LVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYS 485
Query: 363 EVKGVTIAIPQKNS 404
EVK VT+ IPQKNS
Sbjct: 486 EVKTVTVKIPQKNS 499
>sp|P47738|ALDH2_MOUSE Aldehyde dehydrogenase, mitochondrial precursor (ALDH class 2)
(AHD-M1) (ALDHI) (ALDH-E2)
Length = 519
Score = 181 bits (459), Expect = 7e-46
Identities = 86/134 (64%), Positives = 104/134 (77%)
Frame = +3
Query: 3 LVTGGNRIGNVGYFIQPTVFGDVKDNMRIAKEEIFGPVQSVFKFNTMEEVIERANNSDYG 182
L+ GG + GYFIQPTVFGDVKD M IAKEEIFGPV + KF T+EEV+ RAN+S YG
Sbjct: 386 LLCGGGAAADRGYFIQPTVFGDVKDGMTIAKEEIFGPVMQILKFKTIEEVVGRANDSKYG 445
Query: 183 LGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVTAPFGGFKQSGVGRELGCYGLEPYI 362
L A VFT D++KA ++QAL+AG+VW+NCYDV +PFGG+K SG GRELG YGL+ Y
Sbjct: 446 LAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYT 505
Query: 363 EVKGVTIAIPQKNS 404
EVK VT+ +PQKNS
Sbjct: 506 EVKTVTVKVPQKNS 519
>sp|Q63639|AL1A2_RAT Retinal dehydrogenase 2 (RalDH2) (RALDH 2) (RALDH(II))
(Retinaldehyde-specific dehydrogenase type 2) (Aldehyde
dehydrogenase family 1 member A2)
Length = 499
Score = 181 bits (459), Expect = 7e-46
Identities = 85/134 (63%), Positives = 107/134 (79%)
Frame = +3
Query: 3 LVTGGNRIGNVGYFIQPTVFGDVKDNMRIAKEEIFGPVQSVFKFNTMEEVIERANNSDYG 182
L GG +G G+FI+PTVF +V D+MRIAKEEIFGPVQ + +F TM+EVIERANNSD+G
Sbjct: 366 LECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFG 425
Query: 183 LGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVTAPFGGFKQSGVGRELGCYGLEPYI 362
L A VFT+DINKA+M++ A++AG+VW+NCY+ +PFGGFK SG GRE+G +GL Y
Sbjct: 426 LVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYS 485
Query: 363 EVKGVTIAIPQKNS 404
EVK VT+ IPQKNS
Sbjct: 486 EVKTVTVKIPQKNS 499
>sp|P27463|AL1A1_CHICK Retinal dehydrogenase 1 (RalDH1) (RALDH 1) (Aldehyde dehydrogenase
family 1 member A1) (Aldehyde dehydrogenase, cytosolic)
(ALHDII) (ALDH-E1)
Length = 509
Score = 181 bits (458), Expect = 9e-46
Identities = 89/134 (66%), Positives = 101/134 (75%)
Frame = +3
Query: 3 LVTGGNRIGNVGYFIQPTVFGDVKDNMRIAKEEIFGPVQSVFKFNTMEEVIERANNSDYG 182
L GG GN GYFIQPTVF +V D+MRIAKEEIFGPVQ + KF T++EVI+RANN+ YG
Sbjct: 376 LECGGGPWGNKGYFIQPTVFSNVTDDMRIAKEEIFGPVQQIMKFKTIDEVIKRANNTTYG 435
Query: 183 LGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVTAPFGGFKQSGVGRELGCYGLEPYI 362
L A VFT DI+KA+ AL+AG+VWVNCY PFGGFK SG GRELG YGL+ Y
Sbjct: 436 LAAAVFTKDIDKALTFASALQAGTVWVNCYSAFSAQCPFGGFKMSGNGRELGEYGLQEYT 495
Query: 363 EVKGVTIAIPQKNS 404
EVK VTI IPQKNS
Sbjct: 496 EVKTVTIKIPQKNS 509
>sp|P20000|ALDH2_BOVIN Aldehyde dehydrogenase, mitochondrial precursor (ALDH class 2)
(ALDHI) (ALDH-E2)
Length = 520
Score = 180 bits (456), Expect = 2e-45
Identities = 86/134 (64%), Positives = 104/134 (77%)
Frame = +3
Query: 3 LVTGGNRIGNVGYFIQPTVFGDVKDNMRIAKEEIFGPVQSVFKFNTMEEVIERANNSDYG 182
L+ GG + GYFIQPTVFGD++D M IAKEEIFGPV + KF +MEEV+ RANNS YG
Sbjct: 387 LLCGGGAAADRGYFIQPTVFGDLQDGMTIAKEEIFGPVMQILKFKSMEEVVGRANNSKYG 446
Query: 183 LGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVTAPFGGFKQSGVGRELGCYGLEPYI 362
L A VFT D++KA ++QAL+AG+VWVNCYDV +PFGG+K SG GRELG YGL+ Y
Sbjct: 447 LAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKLSGSGRELGEYGLQAYT 506
Query: 363 EVKGVTIAIPQKNS 404
EVK VT+ +PQKNS
Sbjct: 507 EVKTVTVRVPQKNS 520
>sp|P30837|AL1B1_HUMAN Aldehyde dehydrogenase X, mitochondrial precursor (ALDH class 2)
Length = 517
Score = 179 bits (453), Expect = 4e-45
Identities = 87/134 (64%), Positives = 106/134 (79%)
Frame = +3
Query: 3 LVTGGNRIGNVGYFIQPTVFGDVKDNMRIAKEEIFGPVQSVFKFNTMEEVIERANNSDYG 182
L+ GG R G G+FI+PTVFG V+D+MRIAKEEIFGPVQ +FKF +EEV+ERANN+ YG
Sbjct: 384 LLCGGERFGERGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKKIEEVVERANNTRYG 443
Query: 183 LGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVTAPFGGFKQSGVGRELGCYGLEPYI 362
L A VFT D++KA+ TQAL+AG+VWVN Y++ PFGGFK+SG GRELG GL+ Y
Sbjct: 444 LAAAVFTRDLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYT 503
Query: 363 EVKGVTIAIPQKNS 404
EVK VTI +PQKNS
Sbjct: 504 EVKTVTIKVPQKNS 517
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,331,994
Number of Sequences: 369166
Number of extensions: 952670
Number of successful extensions: 2297
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2204
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2231
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2633927485
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)