Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_019_O12 (935 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O00401|WASL_HUMAN Neural Wiskott-Aldrich syndrome protei... 56 1e-07 sp|Q91YD9|WASL_MOUSE Neural Wiskott-Aldrich syndrome protei... 56 1e-07 sp|Q95107|WASL_BOVIN Neural Wiskott-Aldrich syndrome protei... 56 1e-07 sp|O08816|WASL_RAT Neural Wiskott-Aldrich syndrome protein ... 56 1e-07 sp|P42768|WASP_HUMAN Wiskott-Aldrich syndrome protein (WASp) 54 5e-07 sp|P70315|WASP_MOUSE Wiskott-Aldrich syndrome protein homol... 54 5e-07 sp|Q12599|NOR2_CYLTO Cytochrome P450 55A3 (Cytochrome P450N... 32 3.4 sp|P55308|CATA2_HORVU Catalase isozyme 2 31 4.4 sp|O13731|UBR11_SCHPO Ubiquitin-protein ligase E3 component... 31 4.4 sp|O14604|TYBY_HUMAN Thymosin beta-4, Y-chromosomal 31 5.7
>sp|O00401|WASL_HUMAN Neural Wiskott-Aldrich syndrome protein (N-WASP) Length = 505 Score = 56.2 bits (134), Expect = 1e-07 Identities = 34/91 (37%), Positives = 50/91 (54%), Gaps = 3/91 (3%) Frame = +2 Query: 44 RKITKNDISIPTNFQHLDHMGL--NDHFFTSENDENLKKYFKGTQF-EHLLEDKNNLKDI 214 +++TK DI P+NFQH+ H+G N F + D LK F E L+D+ K I Sbjct: 196 KRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVI 255 Query: 215 YDFVEKHGGMSKLETEMKQKENKERRAPAIP 307 YDF+EK GG+ ++ E++ R+AP P Sbjct: 256 YDFIEKTGGVEAVKNELR------RQAPPPP 280
>sp|Q91YD9|WASL_MOUSE Neural Wiskott-Aldrich syndrome protein (N-WASP) Length = 501 Score = 56.2 bits (134), Expect = 1e-07 Identities = 34/91 (37%), Positives = 50/91 (54%), Gaps = 3/91 (3%) Frame = +2 Query: 44 RKITKNDISIPTNFQHLDHMGL--NDHFFTSENDENLKKYFKGTQF-EHLLEDKNNLKDI 214 +++TK DI P+NFQH+ H+G N F + D LK F E L+D+ K I Sbjct: 193 KRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVI 252 Query: 215 YDFVEKHGGMSKLETEMKQKENKERRAPAIP 307 YDF+EK GG+ ++ E++ R+AP P Sbjct: 253 YDFIEKTGGVEAVKNELR------RQAPPPP 277
>sp|Q95107|WASL_BOVIN Neural Wiskott-Aldrich syndrome protein (N-WASP) Length = 505 Score = 56.2 bits (134), Expect = 1e-07 Identities = 34/91 (37%), Positives = 50/91 (54%), Gaps = 3/91 (3%) Frame = +2 Query: 44 RKITKNDISIPTNFQHLDHMGL--NDHFFTSENDENLKKYFKGTQF-EHLLEDKNNLKDI 214 +++TK DI P+NFQH+ H+G N F + D LK F E L+D+ K I Sbjct: 196 KRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVI 255 Query: 215 YDFVEKHGGMSKLETEMKQKENKERRAPAIP 307 YDF+EK GG+ ++ E++ R+AP P Sbjct: 256 YDFIEKTGGVEAVKNELR------RQAPPPP 280
>sp|O08816|WASL_RAT Neural Wiskott-Aldrich syndrome protein (N-WASP) Length = 501 Score = 56.2 bits (134), Expect = 1e-07 Identities = 34/91 (37%), Positives = 50/91 (54%), Gaps = 3/91 (3%) Frame = +2 Query: 44 RKITKNDISIPTNFQHLDHMGL--NDHFFTSENDENLKKYFKGTQF-EHLLEDKNNLKDI 214 +++TK DI P+NFQH+ H+G N F + D LK F E L+D+ K I Sbjct: 193 KRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVI 252 Query: 215 YDFVEKHGGMSKLETEMKQKENKERRAPAIP 307 YDF+EK GG+ ++ E++ R+AP P Sbjct: 253 YDFIEKTGGVEAVKNELR------RQAPPPP 277
>sp|P42768|WASP_HUMAN Wiskott-Aldrich syndrome protein (WASp) Length = 502 Score = 54.3 bits (129), Expect = 5e-07 Identities = 30/84 (35%), Positives = 47/84 (55%), Gaps = 3/84 (3%) Frame = +2 Query: 35 SGPRKITKNDISIPTNFQHLDHMGLN--DHFFTSENDENLKKYFKGTQF-EHLLEDKNNL 205 SG +KI+K DI P+ F+H+ H+G + + F + D +L+ F E L D Sbjct: 228 SGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETS 287 Query: 206 KDIYDFVEKHGGMSKLETEMKQKE 277 K IYDF+E GG+ + EM+++E Sbjct: 288 KLIYDFIEDQGGLEAVRQEMRRQE 311
>sp|P70315|WASP_MOUSE Wiskott-Aldrich syndrome protein homolog (WASp) Length = 520 Score = 54.3 bits (129), Expect = 5e-07 Identities = 30/84 (35%), Positives = 47/84 (55%), Gaps = 3/84 (3%) Frame = +2 Query: 35 SGPRKITKNDISIPTNFQHLDHMGLN--DHFFTSENDENLKKYFKGTQF-EHLLEDKNNL 205 SG +KI+K DI P+ F+H+ H+G + + F + D +L+ F E L D Sbjct: 230 SGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETS 289 Query: 206 KDIYDFVEKHGGMSKLETEMKQKE 277 K IYDF+E GG+ + EM+++E Sbjct: 290 KLIYDFIEDQGGLEAVRQEMRRQE 313
>sp|Q12599|NOR2_CYLTO Cytochrome P450 55A3 (Cytochrome P450NOR2) Length = 408 Score = 31.6 bits (70), Expect = 3.4 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 7/74 (9%) Frame = +2 Query: 32 SSGPRKITKN-----DISIPTNFQHLDHMGLNDHFFTSENDENLKKYFKGTQFEHLLED- 193 S+G + KN D+ P H++ + + FFT ++ ENL+ Y K T + LL D Sbjct: 79 SAGGKAAAKNKPTFVDMDAPA---HMNQRSMVEPFFTEDHVENLRPYIKET-VQGLLNDM 134 Query: 194 -KNNLKDIYDFVEK 232 N ++ D +EK Sbjct: 135 VANGCEEPVDLIEK 148
>sp|P55308|CATA2_HORVU Catalase isozyme 2 Length = 494 Score = 31.2 bits (69), Expect = 4.4 Identities = 13/37 (35%), Positives = 21/37 (56%) Frame = +2 Query: 20 HHAYSSGPRKITKNDISIPTNFQHLDHMGLNDHFFTS 130 HH S +D+ IPT+++H+D G+N + F S Sbjct: 178 HHPESLHTFFFLFDDVGIPTDYRHMDGFGVNTYTFVS 214
>sp|O13731|UBR11_SCHPO Ubiquitin-protein ligase E3 component N-recognin-11 (N-end-recognizing protein 11) Length = 2052 Score = 31.2 bits (69), Expect = 4.4 Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 3/51 (5%) Frame = +2 Query: 173 FEHLLEDKNNLKDIYDFVEKHGGMSKLETE-MKQKENKERRA--PAIPKNT 316 F+H L+D N++ D+ DF + + L E M+ +EN+ A P + +NT Sbjct: 435 FDHPLDDDNDVNDLLDFETEREDIDDLTDEVMETEENEAAEADYPGVNRNT 485
>sp|O14604|TYBY_HUMAN Thymosin beta-4, Y-chromosomal Length = 44 Score = 30.8 bits (68), Expect = 5.7 Identities = 14/30 (46%), Positives = 18/30 (60%) Frame = +2 Query: 551 LSEIVKFDTKKLKNNQNNPRPPLKSKEANE 640 ++EI KFD KLK + + PL SKE E Sbjct: 7 MAEIEKFDKSKLKKTETQEKNPLSSKETIE 36
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 80,476,049 Number of Sequences: 369166 Number of extensions: 1301272 Number of successful extensions: 3681 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3580 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3672 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 9654860130 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)