Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_O04
(876 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P60371|KR106_HUMAN Keratin-associated protein 10-6 (Kera... 55 2e-07
sp|Q8WSW3|MTCD_TETTH Cadmium metallothionein precursor (MT-... 55 3e-07
sp|Q6L8H2|KRA53_HUMAN Keratin-associated protein 5-3 (Kerat... 52 2e-06
sp|P38977|ANTA_HYDMA Antistasin precursor (ATS) (Blood coag... 52 3e-06
sp|O02033|MT_LYTPI Metallothionein (MT) (LpMT1) 50 1e-05
sp|P60372|KR104_HUMAN Keratin-associated protein 10-4 (Kera... 49 1e-05
sp|O97388|MT1_TETPY Metallothionein-1 precursor (MT-1) [Con... 49 1e-05
sp|Q26497|MTA_SPHGR Metallothionein-A (MTA) 49 2e-05
sp|O75690|KRA58_HUMAN Keratin-associated protein 5-8 (Kerat... 49 2e-05
sp|P80394|MT1_TETPI Metallothionein-1 precursor (MT-1) [Con... 49 2e-05
>sp|P60371|KR106_HUMAN Keratin-associated protein 10-6 (Keratin-associated protein 10.6)
(High sulfur keratin-associated protein 10.6)
(Keratin-associated protein 18-6) (Keratin-associated
protein 18.6)
Length = 365
Score = 55.5 bits (132), Expect = 2e-07
Identities = 45/215 (20%), Positives = 61/215 (28%), Gaps = 22/215 (10%)
Frame = +3
Query: 183 SCCQSENCK--CCEGCKSNKEC---TCEGGKCNCDECLKFACSGNKAXXXXXXXXXXXXX 347
SCCQ +C+ CC + C C C C C G+ +
Sbjct: 88 SCCQQSSCQLACCASSPCQQACCVPVCCKTVCCKPVCCVSVCCGDSSCCQQSSCQSACCT 147
Query: 348 XXXXXXXXXXXVCKCKFCKAKDKSCCQSENC------KCCEG------CKSNKECTCEGG 491
VC C SCCQ +C CC+ C+S +C
Sbjct: 148 SSPCQQACCVPVCCKPVCSGISSSCCQQSSCVSCVSSPCCQAVCEPSPCQSGCTSSCTPS 207
Query: 492 KCNCDECLKFACSGNKAXXXXXXXXXXXXXXXXXXXXXXXXVCKCKFCKAKDKSCCQSEN 671
C C C+ + VC C SCCQ +
Sbjct: 208 CCQQSSCQPTCCTSSPC------------QQACCVPVCCVPVCCVPTCSEDSSSCCQQSS 255
Query: 672 CK--CCEGCKSNKEC---TCEGGKCNCDECLKFAC 761
C+ CC C C G +C C + +C
Sbjct: 256 CQPACCTSSPCQHACCVPVCSGASTSC--CQQSSC 288
Score = 45.4 bits (106), Expect = 2e-04
Identities = 46/228 (20%), Positives = 63/228 (27%), Gaps = 31/228 (13%)
Frame = +3
Query: 147 ICKCKFCKAKDKSCCQSENC------KCCEG------CKSNKECTCEGGKCNCDECLKFA 290
+C C SCCQ +C CC+ C+S +C C C
Sbjct: 159 VCCKPVCSGISSSCCQQSSCVSCVSSPCCQAVCEPSPCQSGCTSSCTPSCCQQSSCQPTC 218
Query: 291 CSGNKAXXXXXXXXXXXXXXXXXXXXXXXXVCKCKFCKAKDKSCCQSENCK--CCEGCKS 464
C+ + VC C SCCQ +C+ CC
Sbjct: 219 CTSSPC------------QQACCVPVCCVPVCCVPTCSEDSSSCCQQSSCQPACCTSSPC 266
Query: 465 NKEC---TCEGGKCNCDECLKFACSGNKAXXXXXXXXXXXXXXXXXXXXXXXXVCKCKFC 635
C C G +C C + +C VCK C
Sbjct: 267 QHACCVPVCSGASTSC--CQQSSCQ-------PACCTASCCRSSSSVSLLCHPVCKSTCC 317
Query: 636 ----------KAKDKSCCQSENC--KCCEGCKSNKEC--TCEGGKCNC 737
+ SCC++ +C C S C C G K +C
Sbjct: 318 VPVPSCGASASSCQPSCCRTASCVSLLCRPMCSRPACYSLCSGQKSSC 365
Score = 43.9 bits (102), Expect = 6e-04
Identities = 41/198 (20%), Positives = 57/198 (28%), Gaps = 14/198 (7%)
Frame = +3
Query: 150 CKCKFCK--------AKDKSCCQSENCKCCEGCKSNKECTCEGGKCNCDECLKFACSGNK 305
CK CK D SCCQ +C+ C ++ C C C K CSG
Sbjct: 115 CKTVCCKPVCCVSVCCGDSSCCQQSSCQ--SACCTSSPCQ---QACCVPVCCKPVCSGIS 169
Query: 306 AXXXXXXXXXXXXXXXXXXXXXXXXVCKCKFCKAKDKSCCQSENCK--CCEGCKSNKECT 479
+ C+ + SCCQ +C+ CC + C
Sbjct: 170 SSCCQQSSCVSCVSSPCCQAVCEPSPCQSGCTSSCTPSCCQQSSCQPTCCTSSPCQQAC- 228
Query: 480 CEGGKCNCDECLKFACSGNKAXXXXXXXXXXXXXXXXXXXXXXXXVCKCKFCKAKDKSCC 659
C C+ C + C C SCC
Sbjct: 229 -----CVPVCCVPVCCVPTCSEDSSSCCQQSSCQPACCTSSPCQHACCVPVCSGASTSCC 283
Query: 660 QSENCK--CCEG--CKSN 701
Q +C+ CC C+S+
Sbjct: 284 QQSSCQPACCTASCCRSS 301
Score = 31.6 bits (70), Expect = 3.0
Identities = 29/153 (18%), Positives = 41/153 (26%), Gaps = 6/153 (3%)
Frame = +3
Query: 27 CNCDECLKFACSGNKAXXXXXXXXXXXXXXXXXXXXXXXXICKCKFCKAKDKSCCQSENC 206
C C K CSG + C+ + SCCQ +C
Sbjct: 155 CCVPVCCKPVCSGISSSCCQQSSCVSCVSSPCCQAVCEPSPCQSGCTSSCTPSCCQQSSC 214
Query: 207 K--CCEGCKSNKECTCEGGKCNCDECLKFACSGNKAXXXXXXXXXXXXXXXXXXXXXXXX 380
+ CC + C C C+ C +
Sbjct: 215 QPTCCTSSPCQQAC------CVPVCCVPVCCVPTCSEDSSSCCQQSSCQPACCTSSPCQH 268
Query: 381 VCKCKFCKAKDKSCCQSENCK--CCEG--CKSN 467
C C SCCQ +C+ CC C+S+
Sbjct: 269 ACCVPVCSGASTSCCQQSSCQPACCTASCCRSS 301
>sp|Q8WSW3|MTCD_TETTH Cadmium metallothionein precursor (MT-CD) (CD-MT)
Length = 162
Score = 55.1 bits (131), Expect = 3e-07
Identities = 52/197 (26%), Positives = 65/197 (32%), Gaps = 3/197 (1%)
Frame = +3
Query: 165 CKAKDKSCCQSENCKCCEGCKSNKECTCEGGKC-NCDECLKFA--CSGNKAXXXXXXXXX 335
C +K +CC+S+ +CC G T EG KC NC C A C G A
Sbjct: 26 CVSKTDNCCKSDTKECCTG-------TGEGCKCVNCKCCKPQANCCCGVNAKPCCFDPNS 78
Query: 336 XXXXXXXXXXXXXXXVCKCKFCKAKDKSCCQSENCKCCEGCKSNKECTCEGGKCNCDECL 515
C +K +CC+S+ +CC G T EG KC +C
Sbjct: 79 GCC------------------CVSKTNNCCKSDTKECCTG-------TGEGCKCTSCQCC 113
Query: 516 KFACSGNKAXXXXXXXXXXXXXXXXXXXXXXXXVCKCKFCKAKDKSCCQSENCKCCEGCK 695
K G C C K K+CC N CC K
Sbjct: 114 KPVQQG---------------------------CC----CGDKAKACCTDPNSGCCCSNK 142
Query: 696 SNKECTCEGGKCNCDEC 746
+NK C K C C
Sbjct: 143 ANKCCDAT-SKQECQTC 158
Score = 45.4 bits (106), Expect = 2e-04
Identities = 35/121 (28%), Positives = 46/121 (38%), Gaps = 3/121 (2%)
Frame = +3
Query: 399 CKAKDKSCCQSENCKCCEGCKSNKECTCEGGKC-NCDECLKFA--CSGNKAXXXXXXXXX 569
C +K +CC+S+ +CC G T EG KC NC C A C G A
Sbjct: 26 CVSKTDNCCKSDTKECCTG-------TGEGCKCVNCKCCKPQANCCCGVNAKPCCFDPNS 78
Query: 570 XXXXXXXXXXXXXXXVCKCKFCKAKDKSCCQSENCKCCEGCKSNKECTCEGGKCNCDECL 749
C +K +CC+S+ +CC G T EG KC +C
Sbjct: 79 GCC------------------CVSKTNNCCKSDTKECCTG-------TGEGCKCTSCQCC 113
Query: 750 K 752
K
Sbjct: 114 K 114
Score = 32.0 bits (71), Expect = 2.3
Identities = 16/47 (34%), Positives = 21/47 (44%), Gaps = 1/47 (2%)
Frame = +3
Query: 156 CKFCKAKDKSCCQSENCK-CCEGCKSNKECTCEGGKCNCDECLKFAC 293
C+ CK + CC + K CC S C+ + KC CD K C
Sbjct: 110 CQCCKPVQQGCCCGDKAKACCTDPNSGCCCSNKANKC-CDATSKQEC 155
>sp|Q6L8H2|KRA53_HUMAN Keratin-associated protein 5-3 (Keratin-associated protein 5.3)
(Ultrahigh sulfur keratin-associated protein 5.3)
(Keratin-associated protein 5-9) (Keratin-associated
protein 5.9) (UHS KerB-like)
Length = 238
Score = 52.0 bits (123), Expect = 2e-06
Identities = 57/220 (25%), Positives = 64/220 (29%), Gaps = 24/220 (10%)
Frame = +3
Query: 150 CKCKFCKAKDKSCCQSEN-CKCCEGCKSN-KECTCEGGKCNCDECLKFACS-------GN 302
C C C SC S+ C C GCK C G C C+ CS G+
Sbjct: 52 CSCSSCG----SCGGSKGVCGSCGGCKGGCGSCGGSKGGCGSSCCVPVCCSSSCGSCGGS 107
Query: 303 KAXXXXXXXXXXXXXXXXXXXXXXXXVCKCKFCKAKDKSCCQSENCK-------CCEGCK 461
K C C SCCQS CK CC+ C
Sbjct: 108 KGVCGFRGGSKGGCGSCGCSQCSCYKPCCCS--SGCGSSCCQSSCCKPSCSQSSCCKPCC 165
Query: 462 SN----KECTCEGG---KCNCDECLKFACSGNKAXXXXXXXXXXXXXXXXXXXXXXXXVC 620
S K C C G C C K CS + C
Sbjct: 166 SQSSCCKPCCCSSGCGSSCCQSSCCKPCCSQSSC-------------------------C 200
Query: 621 KCKFCKAK-DKSCCQSENCKCCEGCKSNKECTCEGGKCNC 737
K C + SCCQS CC+ C S C C C C
Sbjct: 201 KPCCCSSGCGSSCCQSS---CCKPCSSQSSC-CVPICCQC 236
>sp|P38977|ANTA_HYDMA Antistasin precursor (ATS) (Blood coagulation factor Xa/proclotting
enzyme inhibitor)
Length = 220
Score = 51.6 bits (122), Expect = 3e-06
Identities = 53/209 (25%), Positives = 76/209 (36%), Gaps = 7/209 (3%)
Frame = +3
Query: 156 CKFCKAKDKSCCQSENCKCCEGCKSNKECTCEGGKCNCDECLKFACSGNKAXXXXXXXXX 335
CKF +D++ C + CKC E + K+C+ K C E + +G +
Sbjct: 30 CKFGFQQDENGC--DICKCAE--RPEKKCSNRYCKMLCPEGFQVDANGCQ---------- 75
Query: 336 XXXXXXXXXXXXXXXVCKCK--FCKAKDKSCCQSENCKC-CEG--CKSNKECT-CEGGKC 497
+C+CK +A +K C + CK CE + C CE KC
Sbjct: 76 ---------------ICRCKRSALEAPEKKCDGLKQCKMHCENGFVRDENGCPKCECSKC 120
Query: 498 NCDECLKFACSGNKAXXXXXXXXXXXXXXXXXXXXXXXXVCKCKFCKAKDKSCCQSENCK 677
+CL F GN+ CKCK K K C + C+
Sbjct: 121 KQFQCLIFCPHGNEV------------------DENGCKTCKCKAAPEK-KKCDDLKQCR 161
Query: 678 C-CEGCKSNKECTCEGGKCNCDECLKFAC 761
CE E C+ KC C++C F C
Sbjct: 162 MFCENGFVRDENGCK--KCECNKCKNFIC 188
Score = 46.2 bits (108), Expect = 1e-04
Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 7/134 (5%)
Frame = +3
Query: 147 ICKCK--FCKAKDKSCCQSENCKC-CEG--CKSNKECT-CEGGKCNCDECLKFACSGNKA 308
IC+CK +A +K C + CK CE + C CE KC +CL F GN+
Sbjct: 76 ICRCKRSALEAPEKKCDGLKQCKMHCENGFVRDENGCPKCECSKCKQFQCLIFCPHGNEV 135
Query: 309 XXXXXXXXXXXXXXXXXXXXXXXXVCKCKFCKAKDKSCCQSENCKC-CEGCKSNKECTCE 485
CKCK K K C + C+ CE E C+
Sbjct: 136 ------------------DENGCKTCKCKAAPEK-KKCDDLKQCRMFCENGFVRDENGCK 176
Query: 486 GGKCNCDECLKFAC 527
KC C++C F C
Sbjct: 177 --KCECNKCKNFIC 188
Score = 36.6 bits (83), Expect = 0.094
Identities = 27/95 (28%), Positives = 34/95 (35%), Gaps = 1/95 (1%)
Frame = +3
Query: 12 CEGGKCNCDECLKFACSGNKAXXXXXXXXXXXXXXXXXXXXXXXXICKCKFCKAKDKSCC 191
CE KC +CL F GN+ CKCK K K C
Sbjct: 115 CECSKCKQFQCLIFCPHGNEV------------------DENGCKTCKCKAAPEK-KKCD 155
Query: 192 QSENCKC-CEGCKSNKECTCEGGKCNCDECLKFAC 293
+ C+ CE E C+ KC C++C F C
Sbjct: 156 DLKQCRMFCENGFVRDENGCK--KCECNKCKNFIC 188
>sp|O02033|MT_LYTPI Metallothionein (MT) (LpMT1)
Length = 68
Score = 49.7 bits (117), Expect = 1e-05
Identities = 27/100 (27%), Positives = 34/100 (34%), Gaps = 3/100 (3%)
Frame = +3
Query: 213 CEGCKSNKECTCEGGKCNCDECLKFACSGNKAXXXXXXXXXXXXXXXXXXXXXXXXVCKC 392
C C+ KEC C GG+C C+ C
Sbjct: 8 CFCCRDGKECACGGGEC----CITGKC--------------------------------- 30
Query: 393 KFCKAKDKSCC---QSENCKCCEGCKSNKECTCEGGKCNC 503
CK D++CC + CKC +GCK C C G C C
Sbjct: 31 --CKEGDRTCCGKCSNAACKCADGCKCEGACACTMGNCTC 68
Score = 49.7 bits (117), Expect = 1e-05
Identities = 27/100 (27%), Positives = 34/100 (34%), Gaps = 3/100 (3%)
Frame = +3
Query: 447 CEGCKSNKECTCEGGKCNCDECLKFACSGNKAXXXXXXXXXXXXXXXXXXXXXXXXVCKC 626
C C+ KEC C GG+C C+ C
Sbjct: 8 CFCCRDGKECACGGGEC----CITGKC--------------------------------- 30
Query: 627 KFCKAKDKSCC---QSENCKCCEGCKSNKECTCEGGKCNC 737
CK D++CC + CKC +GCK C C G C C
Sbjct: 31 --CKEGDRTCCGKCSNAACKCADGCKCEGACACTMGNCTC 68
Score = 44.7 bits (104), Expect = 3e-04
Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 3/40 (7%)
Frame = +3
Query: 159 KFCKAKDKSCC---QSENCKCCEGCKSNKECTCEGGKCNC 269
K CK D++CC + CKC +GCK C C G C C
Sbjct: 29 KCCKEGDRTCCGKCSNAACKCADGCKCEGACACTMGNCTC 68
>sp|P60372|KR104_HUMAN Keratin-associated protein 10-4 (Keratin-associated protein 10.4)
(High sulfur keratin-associated protein 10.4)
(Keratin-associated protein 18-4) (Keratin-associated
protein 18.4)
Length = 401
Score = 49.3 bits (116), Expect = 1e-05
Identities = 39/195 (20%), Positives = 54/195 (27%), Gaps = 19/195 (9%)
Frame = +3
Query: 183 SCCQSENCK--CCEGCKSNKEC---TCEGGKCNCDECLKFACSGNKAXXXXXXXXXXXXX 347
SCCQ +C+ CC + C C C C C G+ +
Sbjct: 88 SCCQQSSCQLACCASSPCQQACCVPVCCKTVCCKPVCCVPVCCGDSSCCQQSSCQSACCT 147
Query: 348 XXXXXXXXXXXVCKCKFCKAKDKSCCQSENC------KCCEG------CKSNKECTCEGG 491
+C C SCCQ +C CC+ C+S +C
Sbjct: 148 SSPCQQACCVPICCKPVCSGISSSCCQQSSCVSCVSSPCCQAVCEPSPCQSGCISSCTPS 207
Query: 492 KCNCDECLKFACSGNKAXXXXXXXXXXXXXXXXXXXXXXXXVCKCKFCKAKDKSCCQSEN 671
C C C+ + VC C SCCQ +
Sbjct: 208 CCQQSSCQPACCTSSSCQQACCVPVCCKT------------VCCKPVCSEDSSSCCQQSS 255
Query: 672 CK--CCEGCKSNKEC 710
C+ CC + C
Sbjct: 256 CQPACCTSSPCQQAC 270
Score = 46.6 bits (109), Expect = 9e-05
Identities = 49/229 (21%), Positives = 66/229 (28%), Gaps = 23/229 (10%)
Frame = +3
Query: 150 CKCKFCK--------AKDKSCCQSENCKCCEGCKSNKECTCEGGKCNCDECLKFACSGNK 305
CK CK D SCCQ +C+ C ++ C C C K CSG
Sbjct: 115 CKTVCCKPVCCVPVCCGDSSCCQQSSCQ--SACCTSSPCQ---QACCVPICCKPVCSGIS 169
Query: 306 AXXXXXXXXXXXXXXXXXXXXXXXXVCKCKFCKAKDKSCCQSENCK--CCEGCKSNKECT 479
+ C+ + SCCQ +C+ CC + C
Sbjct: 170 SSCCQQSSCVSCVSSPCCQAVCEPSPCQSGCISSCTPSCCQQSSCQPACCTSSSCQQACC 229
Query: 480 CEGGKCNCDECLKFACSGNKAXXXXXXXXXXXXXXXXXXXXXXXXVCKCK---------- 629
C C K CS + + CK
Sbjct: 230 VP--VCCKTVCCKPVCSEDSSSCCQQSSCQPACCTSSPCQQACCVPVCCKPVCCKPVGSV 287
Query: 630 -FCKAKDKSCCQSENCK--CCEGCKSNKECTCEGGKCNCDECLKFACSG 767
C CCQ +C+ CC +S + C C C C+ CSG
Sbjct: 288 PICSGASSLCCQQSSCQPACCTSSQSQQGC-CVPVCCKPVSCVP-VCSG 334
Score = 43.5 bits (101), Expect = 8e-04
Identities = 43/205 (20%), Positives = 55/205 (26%), Gaps = 26/205 (12%)
Frame = +3
Query: 147 ICKCKFCKAKDKSCCQSENC------KCCEG------CKSNKECTCEGGKCNCDECLKFA 290
IC C SCCQ +C CC+ C+S +C C C
Sbjct: 159 ICCKPVCSGISSSCCQQSSCVSCVSSPCCQAVCEPSPCQSGCISSCTPSCCQQSSCQPAC 218
Query: 291 CSGNKAXXXXXXXXXXXXXXXXXXXXXXXXVCKCKFCKAKDKSCCQSENCK--CCEGCKS 464
C+ + VC C SCCQ +C+ CC
Sbjct: 219 CTSSSCQQACCVPVCCKT------------VCCKPVCSEDSSSCCQQSSCQPACCTSSPC 266
Query: 465 NKECTCEGGKCNCDECLKFA----CSGNKAXXXXXXXXXXXXXXXXXXXXXXXXVCKCK- 629
+ C C C C CSG + CK
Sbjct: 267 QQAC-CVPVCCKPVCCKPVGSVPICSGASSLCCQQSSCQPACCTSSQSQQGCCVPVCCKP 325
Query: 630 -----FCKAKDKSCCQSENCK--CC 683
C SCCQ +C+ CC
Sbjct: 326 VSCVPVCSGASSSCCQQSSCQPACC 350
Score = 39.7 bits (91), Expect = 0.011
Identities = 28/135 (20%), Positives = 40/135 (29%), Gaps = 17/135 (12%)
Frame = +3
Query: 417 SCCQSENCK--CCEGCKSNKEC---TCEGGKCNCDECLKFACSGNKAXXXXXXXXXXXXX 581
SCCQ +C+ CC + C C C C C G+ +
Sbjct: 88 SCCQQSSCQLACCASSPCQQACCVPVCCKTVCCKPVCCVPVCCGDSSCCQQSSCQSACCT 147
Query: 582 XXXXXXXXXXXVCKCKFCKAKDKSCCQSENC------KCCEG------CKSNKECTCEGG 725
+C C SCCQ +C CC+ C+S +C
Sbjct: 148 SSPCQQACCVPICCKPVCSGISSSCCQQSSCVSCVSSPCCQAVCEPSPCQSGCISSCTPS 207
Query: 726 KCNCDECLKFACSGN 770
C C C+ +
Sbjct: 208 CCQQSSCQPACCTSS 222
>sp|O97388|MT1_TETPY Metallothionein-1 precursor (MT-1) [Contains: Metallothionein-2
(MT-2)]
Length = 107
Score = 49.3 bits (116), Expect = 1e-05
Identities = 29/102 (28%), Positives = 40/102 (39%), Gaps = 3/102 (2%)
Frame = +3
Query: 165 CKAKDKSCCQSENCKCCEGCKSNKECTCEGGKCNCDECLKFACSGNKAXXXXXXXXXXXX 344
C ++ +CC+S+ +CC G + + C C G KC C+ C G+KA
Sbjct: 27 CVSETNNCCKSDKKECCTG--TGEGCKCTGCKC-CEPAKSGCCCGDKAKACCTDPNSGCC 83
Query: 345 XXXXXXXXXXXXVCKCKFCKAKDKSCCQSEN---CKCCEGCK 461
C +K CC S N CK CE CK
Sbjct: 84 ------------------CSSKTNKCCDSTNKTECKTCECCK 107
Score = 48.5 bits (114), Expect = 2e-05
Identities = 31/119 (26%), Positives = 45/119 (37%), Gaps = 1/119 (0%)
Frame = +3
Query: 399 CKAKDKSCCQSENCKCCEGCKSNKECTCEGGKCNCDECLKFACSGNKAXXXXXXXXXXXX 578
C ++ +CC+S+ +CC G + + C C G KC C+ C G+KA
Sbjct: 27 CVSETNNCCKSDKKECCTG--TGEGCKCTGCKC-CEPAKSGCCCGDKA------------ 71
Query: 579 XXXXXXXXXXXXVCKCKFCKAKDKSCCQSENCKCCEGCKSNKEC-TCEGGKCNCDECLK 752
K+CC N CC K+NK C + +C EC K
Sbjct: 72 -----------------------KACCTDPNSGCCCSSKTNKCCDSTNKTECKTCECCK 107
Score = 35.8 bits (81), Expect = 0.16
Identities = 20/58 (34%), Positives = 24/58 (41%), Gaps = 13/58 (22%)
Frame = +3
Query: 150 CKCKFCKA------------KDKSCCQSENCKCCEGCKSNKEC-TCEGGKCNCDECLK 284
CKC CK K K+CC N CC K+NK C + +C EC K
Sbjct: 50 CKCTGCKCCEPAKSGCCCGDKAKACCTDPNSGCCCSSKTNKCCDSTNKTECKTCECCK 107
Score = 32.3 bits (72), Expect = 1.8
Identities = 30/119 (25%), Positives = 34/119 (28%), Gaps = 1/119 (0%)
Frame = +3
Query: 411 DKSCCQSENCK-CCEGCKSNKECTCEGGKCNCDECLKFACSGNKAXXXXXXXXXXXXXXX 587
+ +CC EN K CC S C E C C K C+G
Sbjct: 5 NNNCCCGENAKPCCTDPNSGCCCVSETNNC-CKSDKKECCTGTGEG-------------- 49
Query: 588 XXXXXXXXXVCKCKFCKAKDKSCCQSENCKCCEGCKSNKECTCEGGKCNCDECLKFACS 764
CKC CKCCE KS C + C D CS
Sbjct: 50 ----------CKCT-------------GCKCCEPAKSGCCCGDKAKACCTDPNSGCCCS 85
>sp|Q26497|MTA_SPHGR Metallothionein-A (MTA)
Length = 67
Score = 48.9 bits (115), Expect = 2e-05
Identities = 27/100 (27%), Positives = 35/100 (35%), Gaps = 3/100 (3%)
Frame = +3
Query: 213 CEGCKSNKECTCEGGKCNCDECLKFACSGNKAXXXXXXXXXXXXXXXXXXXXXXXXVCKC 392
C C+ KEC C+GG+C C+ +C
Sbjct: 7 CVCCQDGKECPCKGGEC----CITGSC--------------------------------- 29
Query: 393 KFCKAKDKSCC---QSENCKCCEGCKSNKECTCEGGKCNC 503
CK D CC + CKC +GCK C+C G C C
Sbjct: 30 --CKEGDGLCCGKCSNAACKCADGCKCGSGCSCTLGNCTC 67
Score = 48.9 bits (115), Expect = 2e-05
Identities = 27/100 (27%), Positives = 35/100 (35%), Gaps = 3/100 (3%)
Frame = +3
Query: 447 CEGCKSNKECTCEGGKCNCDECLKFACSGNKAXXXXXXXXXXXXXXXXXXXXXXXXVCKC 626
C C+ KEC C+GG+C C+ +C
Sbjct: 7 CVCCQDGKECPCKGGEC----CITGSC--------------------------------- 29
Query: 627 KFCKAKDKSCC---QSENCKCCEGCKSNKECTCEGGKCNC 737
CK D CC + CKC +GCK C+C G C C
Sbjct: 30 --CKEGDGLCCGKCSNAACKCADGCKCGSGCSCTLGNCTC 67
Score = 41.6 bits (96), Expect = 0.003
Identities = 24/92 (26%), Positives = 31/92 (33%), Gaps = 3/92 (3%)
Frame = +3
Query: 3 ECTCEGGKCNCDECLKFACSGNKAXXXXXXXXXXXXXXXXXXXXXXXXICKCKFCKAKDK 182
EC C+GG+C C+ +C CK D
Sbjct: 15 ECPCKGGEC----CITGSC-----------------------------------CKEGDG 35
Query: 183 SCC---QSENCKCCEGCKSNKECTCEGGKCNC 269
CC + CKC +GCK C+C G C C
Sbjct: 36 LCCGKCSNAACKCADGCKCGSGCSCTLGNCTC 67
Score = 31.6 bits (70), Expect = 3.0
Identities = 19/71 (26%), Positives = 24/71 (33%), Gaps = 13/71 (18%)
Frame = +3
Query: 681 CEGCKSNKECTCEGGKC-------------NCDECLKFACSGNXXXXXXXXXXXXXXXXE 821
C C+ KEC C+GG+C C +C AC
Sbjct: 7 CVCCQDGKECPCKGGECCITGSCCKEGDGLCCGKCSNAACK------------CADGCKC 54
Query: 822 GKGCQCSDGVC 854
G GC C+ G C
Sbjct: 55 GSGCSCTLGNC 65
>sp|O75690|KRA58_HUMAN Keratin-associated protein 5-8 (Keratin-associated protein 5.8)
(Ultrahigh sulfur keratin-associated protein 5.8)
(Keratin, ultra high-sulfur matrix protein B) (UHS
keratin B) (UHS KerB)
Length = 187
Score = 48.5 bits (114), Expect = 2e-05
Identities = 51/213 (23%), Positives = 58/213 (27%), Gaps = 8/213 (3%)
Frame = +3
Query: 150 CKCKFCKAKDKSCCQSE-NCKCCEGCKSNK--ECTCEGGKCNCDECLKFACSGNKAXXXX 320
C C K CC +C C C +K +C G K +C +C G+K
Sbjct: 28 CCVPICCCKPVCCCVPACSCSSCGSCGGSKGGRGSCGGSKGDCG-----SCGGSKGGCGS 82
Query: 321 XXXXXXXXXXXXXXXXXXXXVCKCKFCKAKDKSCCQSENCKCCEGCKSNKECTCEGGKCN 500
C C C CC S GC G C
Sbjct: 83 ---------------------CGCSQCSCYKPCCCSS-------GC---------GSSCC 105
Query: 501 CDECLKFACSGNKAXXXXXXXXXXXXXXXXXXXXXXXXVCK-CKFCKAKDKSCCQSENCK 677
C K CS + CK C SCCQS CK
Sbjct: 106 QSSCCKPCCSQSSC-------------------------CKPCSCSSGCGSSCCQSSCCK 140
Query: 678 -CCEGCKSNKECTCE---GGKCNCDECLKFACS 764
CC K C C G C C K CS
Sbjct: 141 PCCSQSSCCKPCCCSSGCGSSCCQSSCCKPCCS 173
Score = 39.3 bits (90), Expect = 0.015
Identities = 30/103 (29%), Positives = 31/103 (30%), Gaps = 7/103 (6%)
Frame = +3
Query: 9 TCEGGKCNCDECLKFACSGNKAXXXXXXXXXXXXXXXXXXXXXXXXICKCKFCKAKD--- 179
+C G K C C CS K C CK C
Sbjct: 72 SCGGSKGGCGSCGCSQCSCYKPCCCSSGCGSSCCQSSCCKPCCSQSSC-CKPCSCSSGCG 130
Query: 180 KSCCQSENCK-CCEGCKSNKECTCE---GGKCNCDECLKFACS 296
SCCQS CK CC K C C G C C K CS
Sbjct: 131 SSCCQSSCCKPCCSQSSCCKPCCCSSGCGSSCCQSSCCKPCCS 173
>sp|P80394|MT1_TETPI Metallothionein-1 precursor (MT-1) [Contains: Metallothionein-2
(MT-2)]
Length = 107
Score = 48.5 bits (114), Expect = 2e-05
Identities = 29/102 (28%), Positives = 39/102 (38%), Gaps = 3/102 (2%)
Frame = +3
Query: 165 CKAKDKSCCQSENCKCCEGCKSNKECTCEGGKCNCDECLKFACSGNKAXXXXXXXXXXXX 344
C ++ +CC+S+ +CC G + + C C G KC C C G+KA
Sbjct: 27 CVSETNNCCKSDKKECCTG--TGEGCKCTGCKC-CQPAKSGCCCGDKAKACCTDPNSGCC 83
Query: 345 XXXXXXXXXXXXVCKCKFCKAKDKSCCQSEN---CKCCEGCK 461
C +K CC S N CK CE CK
Sbjct: 84 ------------------CSSKTNKCCDSTNKTECKTCECCK 107
Score = 45.4 bits (106), Expect = 2e-04
Identities = 29/109 (26%), Positives = 41/109 (37%), Gaps = 2/109 (1%)
Frame = +3
Query: 399 CKAKDKSCCQSENCKCCEGCKSNKECTCEGGKCNCDECLKFACSGNKAXXXXXXXXXXXX 578
C ++ +CC+S+ +CC G + + C C G KC C C G+KA
Sbjct: 27 CVSETNNCCKSDKKECCTG--TGEGCKCTGCKC-CQPAKSGCCCGDKA------------ 71
Query: 579 XXXXXXXXXXXXVCKCKFCKAKDKS--CCQSENCKCCEGCKSNKECTCE 719
K C S CC S+ KCC+ + TCE
Sbjct: 72 ----------------KACCTDPNSGCCCSSKTNKCCDSTNKTECKTCE 104
Score = 43.1 bits (100), Expect = 0.001
Identities = 35/123 (28%), Positives = 39/123 (31%), Gaps = 2/123 (1%)
Frame = +3
Query: 177 DKSCCQSENCK-CCEGCKSNKECTCEGGKCNCDECLKFACSGNKAXXXXXXXXXXXXXXX 353
+ +CC EN K CC S C E C C K C+G
Sbjct: 5 NNNCCCGENAKPCCTDPNSGCCCVSETNNC-CKSDKKECCTGTGEG-------------- 49
Query: 354 XXXXXXXXXVCKCKFCKAKDKSCCQSENCKCCEGCKSNKECTCEGGKCNCDECLKFAC-S 530
CKC CK CCQ CC G K+ CT C C C S
Sbjct: 50 ----------CKCTGCK-----CCQPAKSGCCCGDKAKACCTDPNSGCCCSSKTNKCCDS 94
Query: 531 GNK 539
NK
Sbjct: 95 TNK 97
Score = 42.7 bits (99), Expect = 0.001
Identities = 32/118 (27%), Positives = 36/118 (30%), Gaps = 1/118 (0%)
Frame = +3
Query: 411 DKSCCQSENCK-CCEGCKSNKECTCEGGKCNCDECLKFACSGNKAXXXXXXXXXXXXXXX 587
+ +CC EN K CC S C E C C K C+G
Sbjct: 5 NNNCCCGENAKPCCTDPNSGCCCVSETNNC-CKSDKKECCTGTGEG-------------- 49
Query: 588 XXXXXXXXXVCKCKFCKAKDKSCCQSENCKCCEGCKSNKECTCEGGKCNCDECLKFAC 761
CKC CK CCQ CC G K+ CT C C C
Sbjct: 50 ----------CKCTGCK-----CCQPAKSGCCCGDKAKACCTDPNSGCCCSSKTNKCC 92
Score = 41.6 bits (96), Expect = 0.003
Identities = 33/130 (25%), Positives = 39/130 (30%), Gaps = 13/130 (10%)
Frame = +3
Query: 402 KAKDKSCCQSENCKCCEGCKSNKECTCEGGKCNCDECLKFACSGNKAXXXXXXXXXXXXX 581
K + CC CC S C E C C K C+G
Sbjct: 3 KVNNNCCCGENAKPCCTDPNSGCCCVSETNNC-CKSDKKECCTGTGEG------------ 49
Query: 582 XXXXXXXXXXXVCKCKFCKA------------KDKSCCQSENCKCCEGCKSNKEC-TCEG 722
CKC CK K K+CC N CC K+NK C +
Sbjct: 50 ------------CKCTGCKCCQPAKSGCCCGDKAKACCTDPNSGCCCSSKTNKCCDSTNK 97
Query: 723 GKCNCDECLK 752
+C EC K
Sbjct: 98 TECKTCECCK 107
Score = 35.0 bits (79), Expect = 0.27
Identities = 20/53 (37%), Positives = 21/53 (39%), Gaps = 1/53 (1%)
Frame = +3
Query: 150 CKCKFCKAKDKSCCQSENCKCCEGCKSNKECTCEGGKCNCDECLKFAC-SGNK 305
CKC CK CCQ CC G K+ CT C C C S NK
Sbjct: 50 CKCTGCK-----CCQPAKSGCCCGDKAKACCTDPNSGCCCSSKTNKCCDSTNK 97
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,892,679
Number of Sequences: 369166
Number of extensions: 1402666
Number of successful extensions: 11439
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2594
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10275
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8694177530
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)