Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_N22
(951 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q12849|GRSF1_HUMAN G-rich sequence factor 1 (GRSF-1) 72 2e-12
sp|Q8C5Q4|GRSF1_MOUSE G-rich sequence factor 1 (GRSF-1) 71 4e-12
sp|P52597|HNRPF_HUMAN Heterogeneous nuclear ribonucleoprote... 70 1e-11
sp|P55795|HNRH2_HUMAN Heterogeneous nuclear ribonucleoprote... 70 1e-11
sp|Q60HC3|HNRPF_MACFA Heterogeneous nuclear ribonucleoprote... 70 1e-11
sp|P70333|HNRH2_MOUSE Heterogeneous nuclear ribonucleoprote... 69 1e-11
sp|O35737|HNRH1_MOUSE Heterogeneous nuclear ribonucleoprote... 67 1e-10
sp|P31943|HNRH1_HUMAN Heterogeneous nuclear ribonucleoprote... 67 1e-10
sp|Q9Y4C8|RBM19_HUMAN Probable RNA-binding protein 19 (RNA-... 52 2e-06
sp|Q9NTZ6|RBM12_HUMAN RNA-binding protein 12 (RNA-binding m... 52 2e-06
>sp|Q12849|GRSF1_HUMAN G-rich sequence factor 1 (GRSF-1)
Length = 447
Score = 72.0 bits (175), Expect = 2e-12
Identities = 42/117 (35%), Positives = 69/117 (58%), Gaps = 6/117 (5%)
Frame = +1
Query: 4 RGLPYSATETDILTFLNGLPIWN-ESGILITLNDDGRPSGEALVKLDNEIGLSDLRDYNG 180
+GLP+S T D+L F + I N E+GI LN DG+ G+AL+++++E + + +
Sbjct: 122 QGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHR 181
Query: 181 KYMGTRFIEVFPATQK--DWFGEEMRMKMSDMT---YVRLRGLPYDVTKEDIFIFFS 336
YMG R++EV+ + D + +++K S + VRLRGLPY ++DI FF+
Sbjct: 182 MYMGQRYVEVYEINNEDVDALMKSLQVKSSPVVNDGVVRLRGLPYSCNEKDIVDFFA 238
Score = 42.0 bits (97), Expect = 0.003
Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNESGILITLNDDG-RPSGEALVKLDNEIGLSDLRDYN 177
LRGLPYS E DI+ F GL N I ++ G R +GEA V+ + + +
Sbjct: 221 LRGLPYSCNEKDIVDFFAGL---NIVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKH 277
Query: 178 GKYMGTRFIEVFPATQKD 231
+ +G R+IE+FP+ + +
Sbjct: 278 REEIGNRYIEIFPSRRNE 295
Score = 32.3 bits (72), Expect = 2.0
Identities = 12/20 (60%), Positives = 16/20 (80%)
Frame = +3
Query: 657 IHMRGLPYSATEKDVHEFFA 716
+ +RGLPYS EKD+ +FFA
Sbjct: 219 VRLRGLPYSCNEKDIVDFFA 238
Score = 32.0 bits (71), Expect = 2.6
Identities = 15/57 (26%), Positives = 30/57 (52%)
Frame = +1
Query: 166 RDYNGKYMGTRFIEVFPATQKDWFGEEMRMKMSDMTYVRLRGLPYDVTKEDIFIFFS 336
R Y+ + T ++ P + + ++ ++ D+ +R +GLP+ T ED+ FFS
Sbjct: 82 RSYSQESKTTYLEDLPPPPEYELAPSKLEEEVDDVFLIRAQGLPWSCTMEDVLNFFS 138
Score = 32.0 bits (71), Expect = 2.6
Identities = 14/33 (42%), Positives = 19/33 (57%)
Frame = +3
Query: 618 ETQNFGEFLGPLSIHMRGLPYSATEKDVHEFFA 716
E +FG +HMRGLP+ A +D+ FFA
Sbjct: 357 EAADFGTTSSLHFVHMRGLPFQANAQDIINFFA 389
Score = 31.6 bits (70), Expect = 3.4
Identities = 17/33 (51%), Positives = 19/33 (57%)
Frame = +2
Query: 791 FYSETDAVKAMEKDRCKMSWRYIELFRGSSALG 889
F + DAV AM KDR + RYIELF S G
Sbjct: 414 FETHEDAVAAMLKDRSHVHHRYIELFLNSCPKG 446
>sp|Q8C5Q4|GRSF1_MOUSE G-rich sequence factor 1 (GRSF-1)
Length = 479
Score = 71.2 bits (173), Expect = 4e-12
Identities = 42/117 (35%), Positives = 69/117 (58%), Gaps = 6/117 (5%)
Frame = +1
Query: 4 RGLPYSATETDILTFLNGLPIWN-ESGILITLNDDGRPSGEALVKLDNEIGLSDLRDYNG 180
+GLP+S T D+L F + I N E+GI LN DG+ G+AL+++++E + + +
Sbjct: 154 QGLPWSCTVEDVLNFFSDCRIRNSENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHR 213
Query: 181 KYMGTRFIEVFPATQK--DWFGEEMRMKMSDMT---YVRLRGLPYDVTKEDIFIFFS 336
YMG R++EV+ + D + +++K S + VRLRGLPY ++DI FF+
Sbjct: 214 MYMGQRYVEVYEINNEDVDALMKSLQVKPSPVLSDGVVRLRGLPYSCNEKDIVDFFA 270
Score = 42.0 bits (97), Expect = 0.003
Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNESGILITLNDDG-RPSGEALVKLDNEIGLSDLRDYN 177
LRGLPYS E DI+ F GL N I ++ G R +GEA V+ + + +
Sbjct: 253 LRGLPYSCNEKDIVDFFAGL---NIVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKH 309
Query: 178 GKYMGTRFIEVFPATQKD 231
+ +G R+IE+FP+ + +
Sbjct: 310 REEIGNRYIEIFPSRRNE 327
Score = 32.3 bits (72), Expect = 2.0
Identities = 12/20 (60%), Positives = 16/20 (80%)
Frame = +3
Query: 657 IHMRGLPYSATEKDVHEFFA 716
+ +RGLPYS EKD+ +FFA
Sbjct: 251 VRLRGLPYSCNEKDIVDFFA 270
Score = 32.0 bits (71), Expect = 2.6
Identities = 14/33 (42%), Positives = 19/33 (57%)
Frame = +3
Query: 618 ETQNFGEFLGPLSIHMRGLPYSATEKDVHEFFA 716
E +FG +HMRGLP+ A +D+ FFA
Sbjct: 389 EAVDFGTLPSLHFVHMRGLPFQANAQDIINFFA 421
Score = 31.6 bits (70), Expect = 3.4
Identities = 17/33 (51%), Positives = 19/33 (57%)
Frame = +2
Query: 791 FYSETDAVKAMEKDRCKMSWRYIELFRGSSALG 889
F + DAV AM KDR + RYIELF S G
Sbjct: 446 FDTHEDAVAAMLKDRSHVQHRYIELFLNSCPKG 478
>sp|P52597|HNRPF_HUMAN Heterogeneous nuclear ribonucleoprotein F (hnRNP F) (Nucleolin-like
protein mcs94-1)
Length = 415
Score = 69.7 bits (169), Expect = 1e-11
Identities = 45/118 (38%), Positives = 66/118 (55%), Gaps = 6/118 (5%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWN-ESGILITLNDDGRPSGEALVKLDNEIGLSDLRDYN 177
LRGLP+S + D+ FL+ I + +G+ +GR SGEA V+L +E + +
Sbjct: 15 LRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALKKD 74
Query: 178 GKYMGTRFIEVFPA--TQKDWFGEEMRMKMSDMT---YVRLRGLPYDVTKEDIFIFFS 336
+ MG R+IEVF + T+ DW + +D +VRLRGLP+ TKE+I FFS
Sbjct: 75 RESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFS 132
Score = 46.6 bits (109), Expect = 1e-04
Identities = 25/77 (32%), Positives = 48/77 (62%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNESGILITLNDDGRPSGEALVKLDNEIGLSDLRDYNG 180
LRGLP+ T+ +I+ F +GL I +GI + ++ +G+ +GEA V+ ++ +
Sbjct: 115 LRGLPFGCTKEEIVQFFSGLEI-VPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHK 173
Query: 181 KYMGTRFIEVFPATQKD 231
+ +G R+IEVF ++Q++
Sbjct: 174 ERIGHRYIEVFKSSQEE 190
Score = 39.7 bits (91), Expect = 0.013
Identities = 26/71 (36%), Positives = 35/71 (49%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNESGILITLNDDGRPSGEALVKLDNEIGLSDLRDYNG 180
+RGLPY ATE DI F + L N + I + DGR +GEA V+ +
Sbjct: 293 MRGLPYKATENDIYNFFSPL---NPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDR 349
Query: 181 KYMGTRFIEVF 213
M R+IE+F
Sbjct: 350 ANMQHRYIELF 360
Score = 36.6 bits (83), Expect = 0.11
Identities = 13/20 (65%), Positives = 17/20 (85%)
Frame = +3
Query: 657 IHMRGLPYSATEKDVHEFFA 716
+HMRGLPY ATE D++ FF+
Sbjct: 291 VHMRGLPYKATENDIYNFFS 310
Score = 35.0 bits (79), Expect = 0.31
Identities = 16/39 (41%), Positives = 24/39 (61%)
Frame = +2
Query: 764 KILEKLKLDFYSETDAVKAMEKDRCKMSWRYIELFRGSS 880
++ + ++F + +AV AM KDR M RYIELF S+
Sbjct: 326 RVTGEADVEFATHEEAVAAMSKDRANMQHRYIELFLNST 364
>sp|P55795|HNRH2_HUMAN Heterogeneous nuclear ribonucleoprotein H' (hnRNP H') (FTP-3)
Length = 449
Score = 69.7 bits (169), Expect = 1e-11
Identities = 43/118 (36%), Positives = 66/118 (55%), Gaps = 6/118 (5%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWN-ESGILITLNDDGRPSGEALVKLDNEIGLSDLRDYN 177
+RGLP+S + +++ F + I N SGI +GRPSGEA V+L++E + +
Sbjct: 15 VRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLALKKD 74
Query: 178 GKYMGTRFIEVFPAT--QKDWFGEEMRMKMSDMT---YVRLRGLPYDVTKEDIFIFFS 336
+ MG R++EVF + + DW + D +VRLRGLP+ +KE+I FFS
Sbjct: 75 RETMGHRYVEVFKSNSVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFS 132
Score = 42.7 bits (99), Expect = 0.001
Identities = 25/78 (32%), Positives = 48/78 (61%), Gaps = 1/78 (1%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNESGILITLNDDGRPSGEALVKL-DNEIGLSDLRDYN 177
LRGLP+ ++ +I+ F +GL I +G+ + ++ GR +GEA V+ EI L+ +
Sbjct: 115 LRGLPFGCSKEEIVQFFSGLEI-VPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHK 173
Query: 178 GKYMGTRFIEVFPATQKD 231
+ +G R+IE+F +++ +
Sbjct: 174 ER-IGHRYIEIFKSSRAE 190
Score = 40.0 bits (92), Expect = 0.010
Identities = 41/142 (28%), Positives = 58/142 (40%), Gaps = 16/142 (11%)
Frame = +3
Query: 339 YIEIYKSSLTEV---------YRAMEKQYEINREEILR--RSRHRQANFPPKFNA---DP 476
YIEI+KSS EV AM++ +R R S R A F
Sbjct: 180 YIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGG 239
Query: 477 YSHVNSY--YTDGYSFPQNKSSQGPMRRSRETKNRSNPYGGKNSHSTKVETQNFGEFLGP 650
Y + Y Y DGY F ++ ++ + + G + H +F G
Sbjct: 240 YGGYDDYGGYNDGYGFGSDRFG----------RDLNYCFSGMSDHRYGDGGSSFQSTTGH 289
Query: 651 LSIHMRGLPYSATEKDVHEFFA 716
+HMRGLPY ATE D++ FF+
Sbjct: 290 C-VHMRGLPYRATENDIYNFFS 310
Score = 38.9 bits (89), Expect = 0.022
Identities = 25/71 (35%), Positives = 35/71 (49%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNESGILITLNDDGRPSGEALVKLDNEIGLSDLRDYNG 180
+RGLPY ATE DI F + L N + I + DGR +GEA V+ +
Sbjct: 293 MRGLPYRATENDIYNFFSPL---NPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDK 349
Query: 181 KYMGTRFIEVF 213
M R++E+F
Sbjct: 350 ANMQHRYVELF 360
Score = 36.2 bits (82), Expect = 0.14
Identities = 16/40 (40%), Positives = 25/40 (62%)
Frame = +2
Query: 764 KILEKLKLDFYSETDAVKAMEKDRCKMSWRYIELFRGSSA 883
++ + ++F + DAV AM KD+ M RY+ELF S+A
Sbjct: 326 RVTGEADVEFATHEDAVAAMAKDKANMQHRYVELFLNSTA 365
>sp|Q60HC3|HNRPF_MACFA Heterogeneous nuclear ribonucleoprotein F (hnRNP F)
Length = 415
Score = 69.7 bits (169), Expect = 1e-11
Identities = 45/118 (38%), Positives = 66/118 (55%), Gaps = 6/118 (5%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWN-ESGILITLNDDGRPSGEALVKLDNEIGLSDLRDYN 177
LRGLP+S + D+ FL+ I + +G+ +GR SGEA V+L +E + +
Sbjct: 15 LRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALKKD 74
Query: 178 GKYMGTRFIEVFPA--TQKDWFGEEMRMKMSDMT---YVRLRGLPYDVTKEDIFIFFS 336
+ MG R+IEVF + T+ DW + +D +VRLRGLP+ TKE+I FFS
Sbjct: 75 RESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFS 132
Score = 46.6 bits (109), Expect = 1e-04
Identities = 25/77 (32%), Positives = 48/77 (62%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNESGILITLNDDGRPSGEALVKLDNEIGLSDLRDYNG 180
LRGLP+ T+ +I+ F +GL I +GI + ++ +G+ +GEA V+ ++ +
Sbjct: 115 LRGLPFGCTKEEIVQFFSGLEI-VPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHK 173
Query: 181 KYMGTRFIEVFPATQKD 231
+ +G R+IEVF ++Q++
Sbjct: 174 ERIGHRYIEVFKSSQEE 190
Score = 39.7 bits (91), Expect = 0.013
Identities = 26/71 (36%), Positives = 35/71 (49%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNESGILITLNDDGRPSGEALVKLDNEIGLSDLRDYNG 180
+RGLPY ATE DI F + L N + I + DGR +GEA V+ +
Sbjct: 293 MRGLPYKATENDIYNFFSPL---NPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDR 349
Query: 181 KYMGTRFIEVF 213
M R+IE+F
Sbjct: 350 ANMQHRYIELF 360
Score = 36.6 bits (83), Expect = 0.11
Identities = 13/20 (65%), Positives = 17/20 (85%)
Frame = +3
Query: 657 IHMRGLPYSATEKDVHEFFA 716
+HMRGLPY ATE D++ FF+
Sbjct: 291 VHMRGLPYKATENDIYNFFS 310
Score = 35.0 bits (79), Expect = 0.31
Identities = 16/39 (41%), Positives = 24/39 (61%)
Frame = +2
Query: 764 KILEKLKLDFYSETDAVKAMEKDRCKMSWRYIELFRGSS 880
++ + ++F + +AV AM KDR M RYIELF S+
Sbjct: 326 RVTGEADVEFATHEEAVAAMSKDRANMQHRYIELFLNST 364
>sp|P70333|HNRH2_MOUSE Heterogeneous nuclear ribonucleoprotein H' (hnRNP H')
Length = 449
Score = 69.3 bits (168), Expect = 1e-11
Identities = 42/118 (35%), Positives = 66/118 (55%), Gaps = 6/118 (5%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWN-ESGILITLNDDGRPSGEALVKLDNEIGLSDLRDYN 177
+RGLP+S + +++ F + I N SG+ +GRPSGEA V+L++E + +
Sbjct: 15 VRGLPWSCSAEEVMRFFSDCKIQNGTSGVRFIYTREGRPSGEAFVELESEDEVKLALKKD 74
Query: 178 GKYMGTRFIEVFPAT--QKDWFGEEMRMKMSDMT---YVRLRGLPYDVTKEDIFIFFS 336
+ MG R++EVF + + DW + D +VRLRGLP+ +KE+I FFS
Sbjct: 75 RETMGHRYVEVFKSNSVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFS 132
Score = 42.7 bits (99), Expect = 0.001
Identities = 25/78 (32%), Positives = 48/78 (61%), Gaps = 1/78 (1%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNESGILITLNDDGRPSGEALVKL-DNEIGLSDLRDYN 177
LRGLP+ ++ +I+ F +GL I +G+ + ++ GR +GEA V+ EI L+ +
Sbjct: 115 LRGLPFGCSKEEIVQFFSGLEI-VPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHK 173
Query: 178 GKYMGTRFIEVFPATQKD 231
+ +G R+IE+F +++ +
Sbjct: 174 ER-IGHRYIEIFKSSRAE 190
Score = 38.9 bits (89), Expect = 0.022
Identities = 41/142 (28%), Positives = 56/142 (39%), Gaps = 16/142 (11%)
Frame = +3
Query: 339 YIEIYKSSLTEV---YRAMEKQYEINREEILRR--------SRHRQANFPPKFNA---DP 476
YIEI+KSS EV Y K + R R S R A F
Sbjct: 180 YIEIFKSSRAEVRTHYDPPRKLMTMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGG 239
Query: 477 YSHVNSY--YTDGYSFPQNKSSQGPMRRSRETKNRSNPYGGKNSHSTKVETQNFGEFLGP 650
Y + Y Y DGY F ++ ++ + + G + H +F G
Sbjct: 240 YGGYDDYGGYNDGYGFGSDRFG----------RDLNYCFSGMSDHRYGDGGSSFQSTTGH 289
Query: 651 LSIHMRGLPYSATEKDVHEFFA 716
+HMRGLPY ATE D++ FF+
Sbjct: 290 C-VHMRGLPYRATENDIYNFFS 310
Score = 38.9 bits (89), Expect = 0.022
Identities = 25/71 (35%), Positives = 35/71 (49%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNESGILITLNDDGRPSGEALVKLDNEIGLSDLRDYNG 180
+RGLPY ATE DI F + L N + I + DGR +GEA V+ +
Sbjct: 293 MRGLPYRATENDIYNFFSPL---NPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDK 349
Query: 181 KYMGTRFIEVF 213
M R++E+F
Sbjct: 350 ANMQHRYVELF 360
Score = 36.2 bits (82), Expect = 0.14
Identities = 16/40 (40%), Positives = 25/40 (62%)
Frame = +2
Query: 764 KILEKLKLDFYSETDAVKAMEKDRCKMSWRYIELFRGSSA 883
++ + ++F + DAV AM KD+ M RY+ELF S+A
Sbjct: 326 RVTGEADVEFATHEDAVAAMAKDKANMQHRYVELFLNSTA 365
>sp|O35737|HNRH1_MOUSE Heterogeneous nuclear ribonucleoprotein H (hnRNP H)
Length = 449
Score = 66.6 bits (161), Expect = 1e-10
Identities = 42/118 (35%), Positives = 65/118 (55%), Gaps = 6/118 (5%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNES-GILITLNDDGRPSGEALVKLDNEIGLSDLRDYN 177
+RGLP+S + ++ F + I N + GI +GRPSGEA V+L++E + +
Sbjct: 15 VRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKD 74
Query: 178 GKYMGTRFIEVFPAT--QKDWFGEEMRMKMSDMT---YVRLRGLPYDVTKEDIFIFFS 336
+ MG R++EVF + + DW + D +VRLRGLP+ +KE+I FFS
Sbjct: 75 RETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFS 132
Score = 43.9 bits (102), Expect = 7e-04
Identities = 26/78 (33%), Positives = 48/78 (61%), Gaps = 1/78 (1%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNESGILITLNDDGRPSGEALVKL-DNEIGLSDLRDYN 177
LRGLP+ ++ +I+ F +GL I +GI + ++ GR +GEA V+ EI L+ +
Sbjct: 115 LRGLPFGCSKEEIVQFFSGLEI-VPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHK 173
Query: 178 GKYMGTRFIEVFPATQKD 231
+ +G R+IE+F +++ +
Sbjct: 174 ER-IGHRYIEIFKSSRAE 190
Score = 39.7 bits (91), Expect = 0.013
Identities = 41/142 (28%), Positives = 57/142 (40%), Gaps = 16/142 (11%)
Frame = +3
Query: 339 YIEIYKSSLTEV---------YRAMEKQYEINREEILR--RSRHRQANFPPKFNA---DP 476
YIEI+KSS EV AM++ +R R S R A F
Sbjct: 180 YIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGG 239
Query: 477 YSHVNSY--YTDGYSFPQNKSSQGPMRRSRETKNRSNPYGGKNSHSTKVETQNFGEFLGP 650
Y + Y Y DGY F ++ ++ + + G + H F G
Sbjct: 240 YGGYDDYNGYNDGYGFGSDRFG----------RDLNYCFSGMSDHRYGDGGSTFQSTTGH 289
Query: 651 LSIHMRGLPYSATEKDVHEFFA 716
+HMRGLPY ATE D++ FF+
Sbjct: 290 C-VHMRGLPYRATENDIYNFFS 310
Score = 39.3 bits (90), Expect = 0.017
Identities = 25/71 (35%), Positives = 35/71 (49%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNESGILITLNDDGRPSGEALVKLDNEIGLSDLRDYNG 180
+RGLPY ATE DI F + L N + I + DGR +GEA V+ +
Sbjct: 293 MRGLPYRATENDIYNFFSPL---NPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDK 349
Query: 181 KYMGTRFIEVF 213
M R++E+F
Sbjct: 350 ANMQHRYVELF 360
Score = 36.6 bits (83), Expect = 0.11
Identities = 16/40 (40%), Positives = 25/40 (62%)
Frame = +2
Query: 764 KILEKLKLDFYSETDAVKAMEKDRCKMSWRYIELFRGSSA 883
++ + ++F + DAV AM KD+ M RY+ELF S+A
Sbjct: 326 RVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTA 365
Score = 30.8 bits (68), Expect = 5.9
Identities = 26/79 (32%), Positives = 31/79 (39%), Gaps = 17/79 (21%)
Frame = +1
Query: 151 GLSDLRDYNGKYMGTRFIEVFPATQKDWFGEEMRM---KMSDMTY--------------V 279
G DYNG G F D FG ++ MSD Y V
Sbjct: 239 GYGGYDDYNGYNDGYGF-------GSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCV 291
Query: 280 RLRGLPYDVTKEDIFIFFS 336
+RGLPY T+ DI+ FFS
Sbjct: 292 HMRGLPYRATENDIYNFFS 310
>sp|P31943|HNRH1_HUMAN Heterogeneous nuclear ribonucleoprotein H (hnRNP H)
Length = 449
Score = 66.6 bits (161), Expect = 1e-10
Identities = 42/118 (35%), Positives = 65/118 (55%), Gaps = 6/118 (5%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNES-GILITLNDDGRPSGEALVKLDNEIGLSDLRDYN 177
+RGLP+S + ++ F + I N + GI +GRPSGEA V+L++E + +
Sbjct: 15 VRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKD 74
Query: 178 GKYMGTRFIEVFPAT--QKDWFGEEMRMKMSDMT---YVRLRGLPYDVTKEDIFIFFS 336
+ MG R++EVF + + DW + D +VRLRGLP+ +KE+I FFS
Sbjct: 75 RETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFS 132
Score = 43.9 bits (102), Expect = 7e-04
Identities = 26/78 (33%), Positives = 48/78 (61%), Gaps = 1/78 (1%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNESGILITLNDDGRPSGEALVKL-DNEIGLSDLRDYN 177
LRGLP+ ++ +I+ F +GL I +GI + ++ GR +GEA V+ EI L+ +
Sbjct: 115 LRGLPFGCSKEEIVQFFSGLEI-VPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHK 173
Query: 178 GKYMGTRFIEVFPATQKD 231
+ +G R+IE+F +++ +
Sbjct: 174 ER-IGHRYIEIFKSSRAE 190
Score = 39.7 bits (91), Expect = 0.013
Identities = 41/142 (28%), Positives = 57/142 (40%), Gaps = 16/142 (11%)
Frame = +3
Query: 339 YIEIYKSSLTEV---------YRAMEKQYEINREEILR--RSRHRQANFPPKFNA---DP 476
YIEI+KSS EV AM++ +R R S R A F
Sbjct: 180 YIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGG 239
Query: 477 YSHVNSY--YTDGYSFPQNKSSQGPMRRSRETKNRSNPYGGKNSHSTKVETQNFGEFLGP 650
Y + Y Y DGY F ++ ++ + + G + H F G
Sbjct: 240 YGGYDDYNGYNDGYGFGSDRFG----------RDLNYCFSGMSDHRYGDGGSTFQSTTGH 289
Query: 651 LSIHMRGLPYSATEKDVHEFFA 716
+HMRGLPY ATE D++ FF+
Sbjct: 290 C-VHMRGLPYRATENDIYNFFS 310
Score = 39.3 bits (90), Expect = 0.017
Identities = 25/71 (35%), Positives = 35/71 (49%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNESGILITLNDDGRPSGEALVKLDNEIGLSDLRDYNG 180
+RGLPY ATE DI F + L N + I + DGR +GEA V+ +
Sbjct: 293 MRGLPYRATENDIYNFFSPL---NPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDK 349
Query: 181 KYMGTRFIEVF 213
M R++E+F
Sbjct: 350 ANMQHRYVELF 360
Score = 36.6 bits (83), Expect = 0.11
Identities = 16/40 (40%), Positives = 25/40 (62%)
Frame = +2
Query: 764 KILEKLKLDFYSETDAVKAMEKDRCKMSWRYIELFRGSSA 883
++ + ++F + DAV AM KD+ M RY+ELF S+A
Sbjct: 326 RVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTA 365
Score = 30.8 bits (68), Expect = 5.9
Identities = 26/79 (32%), Positives = 31/79 (39%), Gaps = 17/79 (21%)
Frame = +1
Query: 151 GLSDLRDYNGKYMGTRFIEVFPATQKDWFGEEMRM---KMSDMTY--------------V 279
G DYNG G F D FG ++ MSD Y V
Sbjct: 239 GYGGYDDYNGYNDGYGF-------GSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCV 291
Query: 280 RLRGLPYDVTKEDIFIFFS 336
+RGLPY T+ DI+ FFS
Sbjct: 292 HMRGLPYRATENDIYNFFS 310
>sp|Q9Y4C8|RBM19_HUMAN Probable RNA-binding protein 19 (RNA-binding motif protein 19)
Length = 960
Score = 52.4 bits (124), Expect = 2e-06
Identities = 41/129 (31%), Positives = 58/129 (44%), Gaps = 17/129 (13%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNESGILITLNDDGRPSGEALVKLDNEIGLSDLRDYNG 180
LRG P++ TE +++ FL L I I N G +G V NE + N
Sbjct: 298 LRGAPFNVTEKNVMEFLAPL---KPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNR 354
Query: 181 KYMGTRFIEVF-----PATQ-------KDWFG-----EEMRMKMSDMTYVRLRGLPYDVT 309
+YMG R+IEVF P T+ K W G E +++ + +R LPY T
Sbjct: 355 EYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTST 414
Query: 310 KEDIFIFFS 336
+ED+ FS
Sbjct: 415 EEDLEKLFS 423
Score = 35.4 bits (80), Expect = 0.24
Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 7/78 (8%)
Frame = +3
Query: 504 DGYSFPQNKSSQGPMRRSRETKNRSN----PYGGKNSHSTKVETQNFGEFLGPLSIH--- 662
+G + SS P+ + R+++ P G K + ET+ P + H
Sbjct: 238 EGSEAEEEDSSATPVLQERDSRGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVK 297
Query: 663 MRGLPYSATEKDVHEFFA 716
+RG P++ TEK+V EF A
Sbjct: 298 LRGAPFNVTEKNVMEFLA 315
>sp|Q9NTZ6|RBM12_HUMAN RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW
domain anchor protein in the nucleus) (SWAN)
Length = 932
Score = 52.0 bits (123), Expect = 2e-06
Identities = 33/101 (32%), Positives = 49/101 (48%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNESGILITLNDDGRPSGEALVKLDNEIGLSDLRDYNG 180
L+GLP+ A ++ F L I +S I I +G+ +GE V+ NE +
Sbjct: 434 LKGLPFEAENKHVIDFFKKLDIVEDS-IYIAYGPNGKATGEGFVEFRNEADYKAALCRHK 492
Query: 181 KYMGTRFIEVFPATQKDWFGEEMRMKMSDMTYVRLRGLPYD 303
+YMG RFI+V P T+K ++ DM RL+ YD
Sbjct: 493 QYMGNRFIQVHPITKKG------MLEKIDMIRKRLQNFSYD 527
Score = 43.9 bits (102), Expect = 7e-04
Identities = 24/78 (30%), Positives = 40/78 (51%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNESGILITLNDDGRPSGEALVKLDNEIGLSDLRDYNG 180
+ G+P+SA E D+ F +GL + + + + GR +G LVK + + N
Sbjct: 308 VHGMPFSAMENDVRDFFHGLRV---DAVHLLKDHVGRNNGNGLVKFLSPQDTFEALKRNR 364
Query: 181 KYMGTRFIEVFPATQKDW 234
M R++EV PAT++ W
Sbjct: 365 MLMIQRYVEVSPATERQW 382
Score = 41.6 bits (96), Expect = 0.003
Identities = 17/49 (34%), Positives = 35/49 (71%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNESGILITLNDDGRPSGEALVKLDNE 147
+ +P+S T+ D+L FL G+P+ +E+ + + ++++G+ G+ALV+ NE
Sbjct: 548 ITNIPFSITKMDVLQFLEGIPV-DENAVHVLVDNNGQGLGQALVQFKNE 595
Score = 31.6 bits (70), Expect = 3.4
Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 1/68 (1%)
Frame = +3
Query: 513 SFPQNKSSQGPMRRSRETKNRS-NPYGGKNSHSTKVETQNFGEFLGPLSIHMRGLPYSAT 689
+F QN G +T RS +P G K S S F ++++GLP+ A
Sbjct: 390 TFKQNMGPSGQTHPPPQTLPRSKSPSGQKRSRSRSPHEAGF-------CVYLKGLPFEAE 442
Query: 690 EKDVHEFF 713
K V +FF
Sbjct: 443 NKHVIDFF 450
Score = 31.2 bits (69), Expect = 4.5
Identities = 17/71 (23%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
Frame = +1
Query: 1 LRGLPYSATETDILTFLNGLPIWNESGILITLNDDGRPSGEALVKLDN-EIGLSDLRDYN 177
++ +P++ + +IL F G + S + + N+ G P+GEA+V ++ + + + D N
Sbjct: 860 VQNMPFTVSIDEILDFFYGYQVIPGS-VCLKYNEKGMPTGEAMVAFESRDEATAAVIDLN 918
Query: 178 GKYMGTRFIEV 210
+ +G+R +++
Sbjct: 919 DRPIGSRKVKL 929
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 110,183,225
Number of Sequences: 369166
Number of extensions: 2260448
Number of successful extensions: 5450
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5095
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5419
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9895030780
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)