Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_N07
(677 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P38624|PSB6_YEAST Proteasome component pre3 precursor (M... 235 7e-62
sp|P28072|PSB6_HUMAN Proteasome subunit beta type 6 precurs... 234 2e-61
sp|P28073|PSB6_RAT Proteasome subunit beta type 6 precursor... 230 3e-60
sp|Q60692|PSB6_MOUSE Proteasome subunit beta type 6 precurs... 228 1e-59
sp|O43063|PSB6_SCHPO Probable proteasome subunit beta type ... 211 1e-54
sp|Q8LD27|PSB6_ARATH Proteasome subunit beta type 6 precurs... 196 5e-50
sp|P93395|PSB6_TOBAC Proteasome subunit beta type 6 precurs... 196 6e-50
sp|P28077|PSB9_RAT Proteasome subunit beta type 9 precursor... 187 2e-47
sp|O35522|PSB9_MUSMB Proteasome subunit beta type 9 precurs... 185 1e-46
sp|P28076|PSB9_MOUSE Proteasome subunit beta type 9 precurs... 183 3e-46
>sp|P38624|PSB6_YEAST Proteasome component pre3 precursor (Macropain subunit pre3)
(Proteinase YSCE subunit pre3) (Multicatalytic
endopeptidase complex subunit pre3)
Length = 215
Score = 235 bits (600), Expect = 7e-62
Identities = 112/206 (54%), Positives = 160/206 (77%), Gaps = 1/206 (0%)
Frame = +2
Query: 26 MNNPGKG-ISMGTTLVAAVFDGGVVIGADSRTSSGTYVSNRVSDKLTQVNDRIYCCRSGS 202
+N KG +S+GT+++A F GV++GADSRT++G Y++NRV+DKLT+V+D+I+CCRSGS
Sbjct: 8 INRLKKGEVSLGTSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGS 67
Query: 203 SADTQALTDVVKYHLELHSNMYNRPVSVLHAATLFKNMCYDYRDQLTAGIIVAGYDDDNG 382
+ADTQA+ D+V+YHLEL+++ Y P S AA++FK +CY+ +D LTAGIIVAGYDD N
Sbjct: 68 AADTQAIADIVQYHLELYTSQYGTP-STETAASVFKELCYENKDNLTAGIIVAGYDDKNK 126
Query: 383 GQIFTIPLGGMIKKQNVSCSGSGSTYILGLMDEVYKENMTEEECIKFVKVSVKHAIIRDG 562
G+++TIPLGG + K + +GSGST+I G D+ ++ENM++EE + F+K S+ AI DG
Sbjct: 127 GEVYTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDG 186
Query: 563 SSGGVIRLAVIGKDGVKRFVFTEDEY 640
SSGGVIR+ V+ GV+R +F DEY
Sbjct: 187 SSGGVIRMVVLTAAGVERLIFYPDEY 212
>sp|P28072|PSB6_HUMAN Proteasome subunit beta type 6 precursor (Proteasome delta chain)
(Macropain delta chain) (Multicatalytic endopeptidase
complex delta chain) (Proteasome subunit Y)
Length = 239
Score = 234 bits (596), Expect = 2e-61
Identities = 110/197 (55%), Positives = 150/197 (76%)
Frame = +2
Query: 47 ISMGTTLVAAVFDGGVVIGADSRTSSGTYVSNRVSDKLTQVNDRIYCCRSGSSADTQALT 226
+S GTT++A FDGGVV+GADSRT++G+Y++NRV+DKLT ++DRI+CCRSGS+ADTQA+
Sbjct: 31 VSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVA 90
Query: 227 DVVKYHLELHSNMYNRPVSVLHAATLFKNMCYDYRDQLTAGIIVAGYDDDNGGQIFTIPL 406
D V Y L HS N P V AA+LFK MCY YR+ L AGII+AG+D GGQ++++P+
Sbjct: 91 DAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPM 150
Query: 407 GGMIKKQNVSCSGSGSTYILGLMDEVYKENMTEEECIKFVKVSVKHAIIRDGSSGGVIRL 586
GGM+ +Q+ + GSGS+YI G +D Y+E MT+EEC++F ++ A+ RDGSSGGVIRL
Sbjct: 151 GGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRL 210
Query: 587 AVIGKDGVKRFVFTEDE 637
A I + GV+R V D+
Sbjct: 211 AAIAESGVERQVLLGDQ 227
>sp|P28073|PSB6_RAT Proteasome subunit beta type 6 precursor (Proteasome delta chain)
(Macropain delta chain) (Multicatalytic endopeptidase
complex delta chain) (Proteasome subunit Y) (Proteasome
chain 5)
Length = 237
Score = 230 bits (586), Expect = 3e-60
Identities = 108/197 (54%), Positives = 149/197 (75%)
Frame = +2
Query: 47 ISMGTTLVAAVFDGGVVIGADSRTSSGTYVSNRVSDKLTQVNDRIYCCRSGSSADTQALT 226
+S GTT++A FDGGVV+GADSRT++G+Y++NRV+DKLT ++D I+CCRSGS+ADTQA+
Sbjct: 29 VSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDHIFCCRSGSAADTQAVA 88
Query: 227 DVVKYHLELHSNMYNRPVSVLHAATLFKNMCYDYRDQLTAGIIVAGYDDDNGGQIFTIPL 406
D V Y L HS N P V AA+LFK MCY YR+ L AGII+AG+D GGQ++++P+
Sbjct: 89 DAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPM 148
Query: 407 GGMIKKQNVSCSGSGSTYILGLMDEVYKENMTEEECIKFVKVSVKHAIIRDGSSGGVIRL 586
GGM+ +Q+ + GSGS+YI G +D Y+E MT++EC++F ++ A+ RDGSSGGVIRL
Sbjct: 149 GGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKDECLQFTANALALAMERDGSSGGVIRL 208
Query: 587 AVIGKDGVKRFVFTEDE 637
A I + GV+R V D+
Sbjct: 209 AAIQQSGVERQVLLGDQ 225
>sp|Q60692|PSB6_MOUSE Proteasome subunit beta type 6 precursor (Proteasome delta chain)
(Macropain delta chain) (Multicatalytic endopeptidase
complex delta chain) (Proteasome subunit Y)
Length = 238
Score = 228 bits (581), Expect = 1e-59
Identities = 107/197 (54%), Positives = 149/197 (75%)
Frame = +2
Query: 47 ISMGTTLVAAVFDGGVVIGADSRTSSGTYVSNRVSDKLTQVNDRIYCCRSGSSADTQALT 226
+S GTT++A F+GGVV+GADSRT++G+Y++NRV+DKLT ++D I+CCRSGS+ADTQA+
Sbjct: 30 VSTGTTIMAVQFNGGVVLGADSRTTTGSYIANRVTDKLTPIHDHIFCCRSGSAADTQAVA 89
Query: 227 DVVKYHLELHSNMYNRPVSVLHAATLFKNMCYDYRDQLTAGIIVAGYDDDNGGQIFTIPL 406
D V Y L HS N P V AA+LFK MCY YR+ L AGII+AG+D GGQ++++P+
Sbjct: 90 DAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPM 149
Query: 407 GGMIKKQNVSCSGSGSTYILGLMDEVYKENMTEEECIKFVKVSVKHAIIRDGSSGGVIRL 586
GGM+ +Q+ + GSGS+YI G +D Y+E MT++EC++F ++ A+ RDGSSGGVIRL
Sbjct: 150 GGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKDECLQFTANALALAMERDGSSGGVIRL 209
Query: 587 AVIGKDGVKRFVFTEDE 637
A I + GV+R V D+
Sbjct: 210 AAIQESGVERQVLLGDQ 226
>sp|O43063|PSB6_SCHPO Probable proteasome subunit beta type 6 precursor
Length = 226
Score = 211 bits (537), Expect = 1e-54
Identities = 102/208 (49%), Positives = 147/208 (70%), Gaps = 1/208 (0%)
Frame = +2
Query: 14 INFIMNNPGKG-ISMGTTLVAAVFDGGVVIGADSRTSSGTYVSNRVSDKLTQVNDRIYCC 190
+N +N KG I MGTT+ A + GV++ ADSRT+ G Y++NRV+DKLTQ+ D I+CC
Sbjct: 9 MNVDINAIKKGEIRMGTTITALRYKDGVILAADSRTTMGAYIANRVTDKLTQLTDNIWCC 68
Query: 191 RSGSSADTQALTDVVKYHLELHSNMYNRPVSVLHAATLFKNMCYDYRDQLTAGIIVAGYD 370
RSGS+ADTQ + D++KY+L ++ + SV AATL MCY ++ L+AG+IVAGYD
Sbjct: 69 RSGSAADTQTVADLLKYYLSMYRIQFGHDPSVHTAATLASEMCYQNKNMLSAGLIVAGYD 128
Query: 371 DDNGGQIFTIPLGGMIKKQNVSCSGSGSTYILGLMDEVYKENMTEEECIKFVKVSVKHAI 550
+ GG +++IPLGG + KQ ++ GSGS +I G D ++ENMT+EE ++F+K +V A+
Sbjct: 129 EKTGGDVYSIPLGGSLHKQPLAIGGSGSAFIYGFCDANFRENMTQEEAVEFLKNAVALAM 188
Query: 551 IRDGSSGGVIRLAVIGKDGVKRFVFTED 634
RDGSSGG IR+ ++ KDG++R F D
Sbjct: 189 ERDGSSGGTIRMVILNKDGMERKFFAID 216
>sp|Q8LD27|PSB6_ARATH Proteasome subunit beta type 6 precursor (Proteasome subunit beta
type 1) (20S proteasome beta subunit A-1) (Proteasome
component CD)
Length = 233
Score = 196 bits (498), Expect = 5e-50
Identities = 91/196 (46%), Positives = 137/196 (69%)
Frame = +2
Query: 50 SMGTTLVAAVFDGGVVIGADSRTSSGTYVSNRVSDKLTQVNDRIYCCRSGSSADTQALTD 229
SMGTT++ ++GGVV+GADSRTS+G YV+NR SDK+TQ+ D +Y CRSGS+AD+Q ++D
Sbjct: 10 SMGTTIIGVTYNGGVVLGADSRTSTGMYVANRASDKITQLTDNVYVCRSGSAADSQVVSD 69
Query: 230 VVKYHLELHSNMYNRPVSVLHAATLFKNMCYDYRDQLTAGIIVAGYDDDNGGQIFTIPLG 409
V+Y L H+ + +P +V +A L + + Y+ ++ L G+IV G+D GG+I+ IPLG
Sbjct: 70 YVRYFLHQHTIQHGQPATVKVSANLIRMLAYNNKNMLQTGLIVGGWDKYEGGKIYGIPLG 129
Query: 410 GMIKKQNVSCSGSGSTYILGLMDEVYKENMTEEECIKFVKVSVKHAIIRDGSSGGVIRLA 589
G + +Q + GSGS+Y+ G D+ +K+NMT+EE + V +V AI RDG+SGGV+R
Sbjct: 130 GTVVEQPFAIGGSGSSYLYGFFDQAWKDNMTKEEAEQLVVKAVSLAIARDGASGGVVRTV 189
Query: 590 VIGKDGVKRFVFTEDE 637
+I +GV R + D+
Sbjct: 190 IINSEGVTRNFYPGDK 205
>sp|P93395|PSB6_TOBAC Proteasome subunit beta type 6 precursor (Proteasome delta chain)
(Tobacco cryptogein-induced protein 7) (tcI 7)
Length = 234
Score = 196 bits (497), Expect = 6e-50
Identities = 93/195 (47%), Positives = 134/195 (68%)
Frame = +2
Query: 50 SMGTTLVAAVFDGGVVIGADSRTSSGTYVSNRVSDKLTQVNDRIYCCRSGSSADTQALTD 229
SMGTT++ ++GGVV+GADSRTS+G YV+NR SDK+TQ+ D +Y CRSGS+AD+Q ++D
Sbjct: 11 SMGTTIIGVTYNGGVVLGADSRTSTGMYVANRASDKITQLTDNVYVCRSGSAADSQIVSD 70
Query: 230 VVKYHLELHSNMYNRPVSVLHAATLFKNMCYDYRDQLTAGIIVAGYDDDNGGQIFTIPLG 409
V+Y L H+ +P +V AA L + + Y+ +D+L G+I+ G+D GG+I+ IP G
Sbjct: 71 YVRYFLHQHTIQLGQPATVKVAANLTRLLSYNNKDRLQTGMIIGGWDKYEGGKIYGIPPG 130
Query: 410 GMIKKQNVSCSGSGSTYILGLMDEVYKENMTEEECIKFVKVSVKHAIIRDGSSGGVIRLA 589
G + +Q + GSGS+Y+ G D+ +KE MT+EE K V +V AI RDG+SGGV+R
Sbjct: 131 GTVLEQPFAIGGSGSSYLYGFFDQAWKEGMTQEEAEKLVVTAVSLAIARDGASGGVVRTV 190
Query: 590 VIGKDGVKRFVFTED 634
I KDG R ++ D
Sbjct: 191 TINKDGATRKFYSGD 205
>sp|P28077|PSB9_RAT Proteasome subunit beta type 9 precursor (Proteasome chain 7)
(Macropain chain 7) (Multicatalytic endopeptidase
complex chain 7) (RING12 protein) (Low molecular mass
protein 2)
Length = 219
Score = 187 bits (475), Expect = 2e-47
Identities = 98/197 (49%), Positives = 127/197 (64%)
Frame = +2
Query: 47 ISMGTTLVAAVFDGGVVIGADSRTSSGTYVSNRVSDKLTQVNDRIYCCRSGSSADTQALT 226
+ GTT++A FDGGVV+G+DSR S+G V NRV DKL+ ++ RIYC SGS+AD QA+
Sbjct: 17 VHTGTTIMAVEFDGGVVVGSDSRVSAGAAVVNRVFDKLSPLHQRIYCALSGSAADAQAIA 76
Query: 227 DVVKYHLELHSNMYNRPVSVLHAATLFKNMCYDYRDQLTAGIIVAGYDDDNGGQIFTIPL 406
D+ Y LELH P VL AA + KN+ Y YR+ L A ++VAG+D GGQ++ +
Sbjct: 77 DMAAYQLELHGLELEEPPLVLAAANIVKNISYKYREDLLAHLMVAGWDQHEGGQVYG-TM 135
Query: 407 GGMIKKQNVSCSGSGSTYILGLMDEVYKENMTEEECIKFVKVSVKHAIIRDGSSGGVIRL 586
GGM+ +Q + GSGSTYI G +D YK MT EEC +F ++ A+ RDGSSGGVI L
Sbjct: 136 GGMLIRQPFAIGGSGSTYIYGYVDAAYKPGMTPEECRRFTTDAITLAMNRDGSSGGVIYL 195
Query: 587 AVIGKDGVKRFVFTEDE 637
I DGV V DE
Sbjct: 196 VTITADGVDHRVILGDE 212
>sp|O35522|PSB9_MUSMB Proteasome subunit beta type 9 precursor (Proteasome chain 7)
(Macropain chain 7) (Multicatalytic endopeptidase
complex chain 7) (RING12 protein) (Low molecular mass
protein 2)
Length = 219
Score = 185 bits (469), Expect = 1e-46
Identities = 98/197 (49%), Positives = 128/197 (64%)
Frame = +2
Query: 47 ISMGTTLVAAVFDGGVVIGADSRTSSGTYVSNRVSDKLTQVNDRIYCCRSGSSADTQALT 226
+ GTT++A FDGGVV+G+DSR S+GT V NRV DKL+ ++ RI+C SGS+AD QA+
Sbjct: 17 VHTGTTIMAVEFDGGVVVGSDSRVSAGTAVVNRVFDKLSPLHQRIFCALSGSAADAQAIA 76
Query: 227 DVVKYHLELHSNMYNRPVSVLHAATLFKNMCYDYRDQLTAGIIVAGYDDDNGGQIFTIPL 406
D+ Y LELH P VL AA + KN+ Y YR+ L A +IVAG+D GGQ++ +
Sbjct: 77 DMAAYQLELHGLELEEPPLVLAAANVVKNISYKYREDLLAHLIVAGWDQREGGQVYG-TM 135
Query: 407 GGMIKKQNVSCSGSGSTYILGLMDEVYKENMTEEECIKFVKVSVKHAIIRDGSSGGVIRL 586
GGM+ +Q + SGSGS+YI G +D YK MT EEC +F ++ A+ RDGSSGGVI L
Sbjct: 136 GGMLIRQPFTISGSGSSYIYGYVDAAYKPGMTPEECRRFTTNAITLAMNRDGSSGGVIYL 195
Query: 587 AVIGKDGVKRFVFTEDE 637
I GV V DE
Sbjct: 196 VTITAAGVDHRVILGDE 212
>sp|P28076|PSB9_MOUSE Proteasome subunit beta type 9 precursor (Proteasome chain 7)
(Macropain chain 7) (Multicatalytic endopeptidase
complex chain 7) (RING12 protein) (Low molecular mass
protein 2) (LMP-2d)
Length = 219
Score = 183 bits (465), Expect = 3e-46
Identities = 97/197 (49%), Positives = 127/197 (64%)
Frame = +2
Query: 47 ISMGTTLVAAVFDGGVVIGADSRTSSGTYVSNRVSDKLTQVNDRIYCCRSGSSADTQALT 226
+ GTT++A FDGGVV+G+DSR S+GT V NRV DKL+ ++ RI+C SGS+AD QA+
Sbjct: 17 VHTGTTIMAVEFDGGVVVGSDSRVSAGTAVVNRVFDKLSPLHQRIFCALSGSAADAQAIA 76
Query: 227 DVVKYHLELHSNMYNRPVSVLHAATLFKNMCYDYRDQLTAGIIVAGYDDDNGGQIFTIPL 406
D+ Y LELH P VL AA + KN+ Y YR+ L A +IVAG+D GGQ++ +
Sbjct: 77 DMAAYQLELHGLELEEPPLVLAAANVVKNISYKYREDLLAHLIVAGWDQREGGQVYG-TM 135
Query: 407 GGMIKKQNVSCSGSGSTYILGLMDEVYKENMTEEECIKFVKVSVKHAIIRDGSSGGVIRL 586
GGM+ +Q + GSGS+YI G +D YK MT EEC +F ++ A+ RDGSSGGVI L
Sbjct: 136 GGMLIRQPFTIGGSGSSYIYGYVDAAYKPGMTPEECRRFTTNAITLAMNRDGSSGGVIYL 195
Query: 587 AVIGKDGVKRFVFTEDE 637
I GV V DE
Sbjct: 196 VTITAAGVDHRVILGDE 212
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,331,723
Number of Sequences: 369166
Number of extensions: 1360491
Number of successful extensions: 3918
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3786
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3864
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5733423530
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)