Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_M23
(919 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P19179|FIMB_CHICK Fimbrin 216 9e-56
sp|Q99K51|PLST_MOUSE T-plastin (Plastin-3) 214 3e-55
sp|Q61233|PLSL_MOUSE L-plastin (Lymphocyte cytosolic protei... 214 4e-55
sp|O88818|PLST_CRIGR T-plastin (Plastin-3) 214 4e-55
sp|Q63598|PLST_RAT T-plastin (Plastin-3) 213 5e-55
sp|P13797|PLST_HUMAN T-plastin (Plastin-3) 212 1e-54
sp|Q6P698|PLSL_BRARE L-plastin (Lymphocyte cytosolic plasti... 211 2e-54
sp|P13796|PLSL_HUMAN L-plastin (Lymphocyte cytosolic protei... 209 7e-54
sp|Q14651|PLSI_HUMAN I-plastin (Intestine-specific plastin)... 208 1e-53
sp|P54680|FIMB_DICDI Fimbrin 206 7e-53
>sp|P19179|FIMB_CHICK Fimbrin
Length = 630
Score = 216 bits (549), Expect = 9e-56
Identities = 133/322 (41%), Positives = 181/322 (56%), Gaps = 16/322 (4%)
Frame = +2
Query: 2 NLCLAVNSAEAIGCCMVNIGSEDIEKGTKHLVLGLVWQVIRXXXXXXXXXXXXAELVALL 181
NL LA+NSA AIGC +VNIGS+D+++G HLVLGL+WQ+I+ L+ALL
Sbjct: 195 NLNLALNSASAIGCTVVNIGSQDLQEGKPHLVLGLLWQIIKVGLFADIEISRNEALIALL 254
Query: 182 REDETLDDLKQLSPEELLLRWVNYHLEKAGITKRITNFKEDIQDSEIYSHLLYQIAP-SD 358
E E LD L +LSPEELLLRWVNYHL AG ++I+NF +DI+DS Y HLL QIAP D
Sbjct: 255 NEGEELDQLMKLSPEELLLRWVNYHLANAG-WQKISNFSQDIRDSRAYYHLLNQIAPKGD 313
Query: 359 KRDEMLPPVAI--LKNTDNMKRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLNLA 532
DE+ + + ++++RAE ML A + R F+ P DV KLNLA
Sbjct: 314 DFDEIHVEIDFSGFNDKNDLRRAECMLQQADKLGCRQFVTPADVV------AGNPKLNLA 367
Query: 533 FVANLFNTYPALIVD-----SXXXXXXXXXXXKTYRNWINSMGVTPYVKDLYSDXXXXXX 697
FVANLFNTYPAL +T+RNW+NS+GV+PYV LYSD
Sbjct: 368 FVANLFNTYPALHKPDNSSYDLTLLEGESNEERTFRNWMNSLGVSPYVNHLYSDLSDALI 427
Query: 698 XXXXXXXXQPGIVEWKKIVRVFDPKKKIFQVLG-------NCAHVIECAK-KLQLSIVNL 853
+ V+W + K+ + +LG NC + +E K K + S+V +
Sbjct: 428 IFQLYEMTRVP-VDWTHV------NKRPYPLLGGNMKKIENCNYAVELGKTKAKFSLVGI 480
Query: 854 SADNIKDATPNLTLGLCFQMLR 919
+ ++ + P LTL L +Q++R
Sbjct: 481 AGHDLNEGNPTLTLALIWQLMR 502
Score = 53.9 bits (128), Expect = 6e-07
Identities = 43/150 (28%), Positives = 69/150 (46%), Gaps = 1/150 (0%)
Frame = +2
Query: 47 MVNIGSEDIEKGTKHLVLGLVWQVIRXXXXXXXXXXXXAELVALLREDETLDDLKQLSPE 226
+V I D+ +G L L L+WQ++R +++ L E E ++D
Sbjct: 477 LVGIAGHDLNEGNPTLTLALIWQLMRRYTL---------NVLSDLGEGEKVND------- 520
Query: 227 ELLLRWVNYHLEKAGITKRITNFKE-DIQDSEIYSHLLYQIAPSDKRDEMLPPVAILKNT 403
E++++WVN L A IT+FK+ I S L+ IAP R EM+ L
Sbjct: 521 EIIIKWVNQTLANANKKTSITSFKDKSISTSLPVLDLIDAIAPKAVRQEMVKR-EDLSYQ 579
Query: 404 DNMKRAELMLGNASLIDARVFIEPEDVALV 493
D + A+ + A I AR++ P+D+ V
Sbjct: 580 DKLNNAKYAISVARKIGARIYALPDDLVEV 609
Score = 31.2 bits (69), Expect = 4.3
Identities = 14/52 (26%), Positives = 31/52 (59%), Gaps = 2/52 (3%)
Frame = +2
Query: 770 KKKI--FQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLTLGLCFQMLR 919
KKK+ F + N + A + ++VN+ + ++++ P+L LGL +Q+++
Sbjct: 184 KKKLTPFTISENLNLALNSASAIGCTVVNIGSQDLQEGKPHLVLGLLWQIIK 235
>sp|Q99K51|PLST_MOUSE T-plastin (Plastin-3)
Length = 627
Score = 214 bits (545), Expect = 3e-55
Identities = 131/317 (41%), Positives = 177/317 (55%), Gaps = 11/317 (3%)
Frame = +2
Query: 2 NLCLAVNSAEAIGCCMVNIGSEDIEKGTKHLVLGLVWQVIRXXXXXXXXXXXXAELVALL 181
NL LA+NSA AIGC +VNIG+ED+ G HLVLGL+WQ+I+ L ALL
Sbjct: 193 NLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALL 252
Query: 182 REDETLDDLKQLSPEELLLRWVNYHLEKAGITKRITNFKEDIQDSEIYSHLLYQIAPSDK 361
R+ ETL++L +LSPEELLLRW N+HLE +G ++I NF DI+DS+ Y HLL QIAP +
Sbjct: 253 RDGETLEELMKLSPEELLLRWANFHLENSG-WQKINNFSADIKDSKAYFHLLNQIAPKGQ 311
Query: 362 RDEMLPPVAI----LKNTDNMKRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLNL 529
+ E P + I TD++KRAE ML A + R F+ P DV KLNL
Sbjct: 312 K-EGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVV------SGNPKLNL 364
Query: 530 AFVANLFNTYPALIVD-----SXXXXXXXXXXXKTYRNWINSMGVTPYVKDLYSDXXXXX 694
AFVANLFN YPAL +T+RNW+NS+GV P+V LY+D
Sbjct: 365 AFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADLQDAL 424
Query: 695 XXXXXXXXXQPGIVEWKKIVRVFDPKKKI-FQVLGNCAHVIECAKK-LQLSIVNLSADNI 868
+ V+W K+ + PK + L NC + +E K + S+V + ++
Sbjct: 425 VILQLYERIKVP-VDWSKVNKPPYPKLGANMKKLENCNYAVELGKNPAKFSLVGIGGQDL 483
Query: 869 KDATPNLTLGLCFQMLR 919
D P LTL + +Q++R
Sbjct: 484 NDGNPTLTLAVVWQLMR 500
Score = 47.0 bits (110), Expect = 7e-05
Identities = 41/152 (26%), Positives = 66/152 (43%), Gaps = 3/152 (1%)
Frame = +2
Query: 47 MVNIGSEDIEKGTKHLVLGLVWQVIRXXXXXXXXXXXXAELVALLREDETLDDLK--QLS 220
+V IG +D+ G L L +VWQ++R L+DL Q +
Sbjct: 475 LVGIGGQDLNDGNPTLTLAVVWQLMRRYTL------------------NVLEDLGEGQKA 516
Query: 221 PEELLLRWVNYHLEKAGITKRITNFKE-DIQDSEIYSHLLYQIAPSDKRDEMLPPVAILK 397
+++++ WVN L +AG + I +FK+ I S L+ I P +++ L
Sbjct: 517 NDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKS-GNLT 575
Query: 398 NTDNMKRAELMLGNASLIDARVFIEPEDVALV 493
D A+ + A I ARV+ PED+ V
Sbjct: 576 EDDKHNNAKYAVSMARRIGARVYALPEDLVEV 607
Score = 30.4 bits (67), Expect = 7.3
Identities = 15/52 (28%), Positives = 30/52 (57%), Gaps = 2/52 (3%)
Frame = +2
Query: 770 KKKI--FQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLTLGLCFQMLR 919
KKK+ F + N + A + +VN+ A++++ P+L LGL +Q+++
Sbjct: 182 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIK 233
>sp|Q61233|PLSL_MOUSE L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage
protein) (pp65)
Length = 627
Score = 214 bits (544), Expect = 4e-55
Identities = 132/317 (41%), Positives = 182/317 (57%), Gaps = 11/317 (3%)
Frame = +2
Query: 2 NLCLAVNSAEAIGCCMVNIGSEDIEKGTKHLVLGLVWQVIRXXXXXXXXXXXXAELVALL 181
NL LA+NSA AIGC +VNIG+ED+++G +LVLGL+WQVI+ L+ALL
Sbjct: 193 NLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALIALL 252
Query: 182 REDETLDDLKQLSPEELLLRWVNYHLEKAGITKRITNFKEDIQDSEIYSHLLYQIAPSDK 361
RE E+L+DL +LSPEELLLRW NYHLE AG TK ITNF DI+DS+ Y HLL Q+AP
Sbjct: 253 REGESLEDLMKLSPEELLLRWANYHLENAGCTK-ITNFSTDIKDSKAYYHLLEQVAPKGD 311
Query: 362 RDEMLPPVAI----LKNTDNMKRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLNL 529
+E +P V I L+ D+++RAE ML A + R F+ DV + KLNL
Sbjct: 312 -EEGIPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVV------RGNPKLNL 364
Query: 530 AFVANLFNTYPALIVD-----SXXXXXXXXXXXKTYRNWINSMGVTPYVKDLYSDXXXXX 694
AF+ANLFN YPAL +T+RNW+NS+GV P V LYSD
Sbjct: 365 AFIANLFNKYPALHKPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDLSDAL 424
Query: 695 XXXXXXXXXQPGIVEWKKIVRVFDPK-KKIFQVLGNCAHVIECAK-KLQLSIVNLSADNI 868
+ V+W ++ + PK + L NC + ++ K + + S+V ++ ++
Sbjct: 425 VIFQLYEKIKVP-VDWNRVNKPPYPKLGGNMKKLENCNYAVDLGKNQAKFSLVGIAGQDL 483
Query: 869 KDATPNLTLGLCFQMLR 919
+ LTL L +Q++R
Sbjct: 484 NEGNRTLTLALVWQLMR 500
Score = 45.8 bits (107), Expect = 2e-04
Identities = 39/155 (25%), Positives = 69/155 (44%), Gaps = 3/155 (1%)
Frame = +2
Query: 47 MVNIGSEDIEKGTKHLVLGLVWQVIRXXXXXXXXXXXXAELVALLREDETLDDLK--QLS 220
+V I +D+ +G + L L LVWQ++R L+D+ Q
Sbjct: 475 LVGIAGQDLNEGNRTLTLALVWQLMRRYTL------------------NILEDIGGGQKV 516
Query: 221 PEELLLRWVNYHLEKAGITKRITNFKE-DIQDSEIYSHLLYQIAPSDKRDEMLPPVAILK 397
+++++ WVN L++A + I +FK+ I S L+ I P ++L L
Sbjct: 517 NDDIIVNWVNTTLKEAQKSSSIASFKDPKISTSLPVLDLIDAIQPGSINYDLL-KTENLD 575
Query: 398 NTDNMKRAELMLGNASLIDARVFIEPEDVALVTQR 502
+ + + A+ + A I ARV+ PED+ V +
Sbjct: 576 DEEKLNNAKYAISMARKIGARVYALPEDLVEVNPK 610
Score = 32.7 bits (73), Expect = 1.5
Identities = 16/52 (30%), Positives = 30/52 (57%), Gaps = 2/52 (3%)
Frame = +2
Query: 770 KKKI--FQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLTLGLCFQMLR 919
KKK+ F + N + A + +VN+ A+++K+ P L LGL +Q+++
Sbjct: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIK 233
>sp|O88818|PLST_CRIGR T-plastin (Plastin-3)
Length = 627
Score = 214 bits (544), Expect = 4e-55
Identities = 131/317 (41%), Positives = 177/317 (55%), Gaps = 11/317 (3%)
Frame = +2
Query: 2 NLCLAVNSAEAIGCCMVNIGSEDIEKGTKHLVLGLVWQVIRXXXXXXXXXXXXAELVALL 181
NL LA+NSA AIGC +VNIG+ED+ G HLVLGL+WQ+I+ L ALL
Sbjct: 193 NLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALL 252
Query: 182 REDETLDDLKQLSPEELLLRWVNYHLEKAGITKRITNFKEDIQDSEIYSHLLYQIAPSDK 361
R+ ETL++L +LSPEELLLRW N+HLE +G ++I NF DI+DS+ Y HLL QIAP +
Sbjct: 253 RDGETLEELMKLSPEELLLRWANFHLENSG-WQKINNFSADIKDSKAYFHLLNQIAPKGQ 311
Query: 362 RDEMLPPVAI----LKNTDNMKRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLNL 529
+ E P + I TD++KRAE ML A + R F+ P DV KLNL
Sbjct: 312 K-EGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVV------SGNPKLNL 364
Query: 530 AFVANLFNTYPALIVD-----SXXXXXXXXXXXKTYRNWINSMGVTPYVKDLYSDXXXXX 694
AFVANLFN YPAL +T+RNW+NS+GV P+V LY+D
Sbjct: 365 AFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADLQDAL 424
Query: 695 XXXXXXXXXQPGIVEWKKIVRVFDPKKKI-FQVLGNCAHVIECAK-KLQLSIVNLSADNI 868
+ V+W K+ + PK + L NC + +E K + S+V + ++
Sbjct: 425 VILQLYERIKVP-VDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDL 483
Query: 869 KDATPNLTLGLCFQMLR 919
D P LTL + +Q++R
Sbjct: 484 NDGNPTLTLAVVWQLMR 500
Score = 47.0 bits (110), Expect = 7e-05
Identities = 41/152 (26%), Positives = 66/152 (43%), Gaps = 3/152 (1%)
Frame = +2
Query: 47 MVNIGSEDIEKGTKHLVLGLVWQVIRXXXXXXXXXXXXAELVALLREDETLDDLK--QLS 220
+V IG +D+ G L L +VWQ++R L+DL Q +
Sbjct: 475 LVGIGGQDLNDGNPTLTLAVVWQLMRRYTL------------------NVLEDLGEGQKA 516
Query: 221 PEELLLRWVNYHLEKAGITKRITNFKE-DIQDSEIYSHLLYQIAPSDKRDEMLPPVAILK 397
+++++ WVN L +AG + I +FK+ I S L+ I P +++ L
Sbjct: 517 NDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKS-GNLT 575
Query: 398 NTDNMKRAELMLGNASLIDARVFIEPEDVALV 493
D A+ + A I ARV+ PED+ V
Sbjct: 576 EDDKHNNAKYAVSMARRIGARVYALPEDLVEV 607
Score = 30.4 bits (67), Expect = 7.3
Identities = 15/52 (28%), Positives = 30/52 (57%), Gaps = 2/52 (3%)
Frame = +2
Query: 770 KKKI--FQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLTLGLCFQMLR 919
KKK+ F + N + A + +VN+ A++++ P+L LGL +Q+++
Sbjct: 182 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIK 233
>sp|Q63598|PLST_RAT T-plastin (Plastin-3)
Length = 627
Score = 213 bits (543), Expect = 5e-55
Identities = 131/317 (41%), Positives = 177/317 (55%), Gaps = 11/317 (3%)
Frame = +2
Query: 2 NLCLAVNSAEAIGCCMVNIGSEDIEKGTKHLVLGLVWQVIRXXXXXXXXXXXXAELVALL 181
NL LA+NSA AIGC +VNIG+ED+ G HLVLGL+WQ+I+ L ALL
Sbjct: 193 NLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALL 252
Query: 182 REDETLDDLKQLSPEELLLRWVNYHLEKAGITKRITNFKEDIQDSEIYSHLLYQIAPSDK 361
R+ ETL++L +LSPEELLLRW N+HLE +G ++I NF DI+DS+ Y HLL QIAP +
Sbjct: 253 RDGETLEELMKLSPEELLLRWANFHLENSG-WQKINNFSADIKDSKAYFHLLNQIAPKGQ 311
Query: 362 RDEMLPPVAI----LKNTDNMKRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLNL 529
+ E P + I TD++KRAE ML A + R F+ P DV KLNL
Sbjct: 312 K-EGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVV------SGNPKLNL 364
Query: 530 AFVANLFNTYPALIVD-----SXXXXXXXXXXXKTYRNWINSMGVTPYVKDLYSDXXXXX 694
AFVANLFN YPAL +T+RNW+NS+GV P+V LY D
Sbjct: 365 AFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYVDLQDAL 424
Query: 695 XXXXXXXXXQPGIVEWKKIVRVFDPKKKI-FQVLGNCAHVIECAK-KLQLSIVNLSADNI 868
+ V+W K+ + PK + L NC + +E K + + S+V + ++
Sbjct: 425 VILQLYERIKVP-VDWSKVNKPPYPKLGANMKKLENCNYAVELGKNQAKFSLVGIGGQDL 483
Query: 869 KDATPNLTLGLCFQMLR 919
D P LTL + +Q++R
Sbjct: 484 NDGNPTLTLAVVWQLMR 500
Score = 46.6 bits (109), Expect = 1e-04
Identities = 40/152 (26%), Positives = 66/152 (43%), Gaps = 3/152 (1%)
Frame = +2
Query: 47 MVNIGSEDIEKGTKHLVLGLVWQVIRXXXXXXXXXXXXAELVALLREDETLDDLK--QLS 220
+V IG +D+ G L L +VWQ++R ++DL Q +
Sbjct: 475 LVGIGGQDLNDGNPTLTLAVVWQLMRRYTL------------------NVMEDLGEGQKA 516
Query: 221 PEELLLRWVNYHLEKAGITKRITNFKE-DIQDSEIYSHLLYQIAPSDKRDEMLPPVAILK 397
+++++ WVN L +AG + I +FK+ I S L+ I P +++ L
Sbjct: 517 TDDIIVNWVNGTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLV-KTGNLT 575
Query: 398 NTDNMKRAELMLGNASLIDARVFIEPEDVALV 493
D A+ + A I ARV+ PED+ V
Sbjct: 576 EEDKHNNAKYAVSMARRIGARVYALPEDLVEV 607
Score = 30.4 bits (67), Expect = 7.3
Identities = 15/52 (28%), Positives = 30/52 (57%), Gaps = 2/52 (3%)
Frame = +2
Query: 770 KKKI--FQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLTLGLCFQMLR 919
KKK+ F + N + A + +VN+ A++++ P+L LGL +Q+++
Sbjct: 182 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIK 233
>sp|P13797|PLST_HUMAN T-plastin (Plastin-3)
Length = 627
Score = 212 bits (539), Expect = 1e-54
Identities = 131/317 (41%), Positives = 176/317 (55%), Gaps = 11/317 (3%)
Frame = +2
Query: 2 NLCLAVNSAEAIGCCMVNIGSEDIEKGTKHLVLGLVWQVIRXXXXXXXXXXXXAELVALL 181
NL LA+NSA AIGC +VNIG+ED+ G HLVLGL+WQ+I+ L ALL
Sbjct: 193 NLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALL 252
Query: 182 REDETLDDLKQLSPEELLLRWVNYHLEKAGITKRITNFKEDIQDSEIYSHLLYQIAPSDK 361
R+ ETL++L +LSPEELLLRW N+HLE +G ++I NF DI+DS+ Y HLL QIAP +
Sbjct: 253 RDGETLEELMKLSPEELLLRWANFHLENSG-WQKINNFSADIKDSKAYFHLLNQIAPKGQ 311
Query: 362 RDEMLPPVAI----LKNTDNMKRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLNL 529
+ E P + I TD++KRAE ML A + R F+ P DV KLNL
Sbjct: 312 K-EGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVV------SGNPKLNL 364
Query: 530 AFVANLFNTYPALIVD-----SXXXXXXXXXXXKTYRNWINSMGVTPYVKDLYSDXXXXX 694
AFVANLFN YPAL +T+RNW+NS+GV P+V LY+D
Sbjct: 365 AFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADLQDAL 424
Query: 695 XXXXXXXXXQPGIVEWKKIVRVFDPKKKI-FQVLGNCAHVIECAK-KLQLSIVNLSADNI 868
+ V+W K+ + PK + L NC + +E K + S+V + ++
Sbjct: 425 VILQLYERIKVP-VDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDL 483
Query: 869 KDATPNLTLGLCFQMLR 919
D LTL L +Q++R
Sbjct: 484 NDGNQTLTLALVWQLMR 500
Score = 48.9 bits (115), Expect = 2e-05
Identities = 42/152 (27%), Positives = 67/152 (44%), Gaps = 3/152 (1%)
Frame = +2
Query: 47 MVNIGSEDIEKGTKHLVLGLVWQVIRXXXXXXXXXXXXAELVALLREDETLDDLK--QLS 220
+V IG +D+ G + L L LVWQ++R L+DL Q +
Sbjct: 475 LVGIGGQDLNDGNQTLTLALVWQLMRRYTL------------------NVLEDLGDGQKA 516
Query: 221 PEELLLRWVNYHLEKAGITKRITNFKE-DIQDSEIYSHLLYQIAPSDKRDEMLPPVAILK 397
+++++ WVN L +AG + I +FK+ I S L+ I P +++ L
Sbjct: 517 NDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKS-GNLT 575
Query: 398 NTDNMKRAELMLGNASLIDARVFIEPEDVALV 493
D A+ + A I ARV+ PED+ V
Sbjct: 576 EDDKHNNAKYAVSMARRIGARVYALPEDLVEV 607
Score = 30.4 bits (67), Expect = 7.3
Identities = 15/52 (28%), Positives = 30/52 (57%), Gaps = 2/52 (3%)
Frame = +2
Query: 770 KKKI--FQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLTLGLCFQMLR 919
KKK+ F + N + A + +VN+ A++++ P+L LGL +Q+++
Sbjct: 182 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIK 233
>sp|Q6P698|PLSL_BRARE L-plastin (Lymphocyte cytosolic plastin 1)
Length = 624
Score = 211 bits (538), Expect = 2e-54
Identities = 132/318 (41%), Positives = 183/318 (57%), Gaps = 12/318 (3%)
Frame = +2
Query: 2 NLCLAVNSAEAIGCCMVNIGSEDIEKGTKHLVLGLVWQVIRXXXXXXXXXXXXAELVALL 181
NL LA+NSA AIGC +VNIG+ED+++G +HLVLGL+WQVI+ L+ALL
Sbjct: 191 NLNLALNSASAIGCHVVNIGAEDLKEGRQHLVLGLLWQVIKIGLFADIEISRNEALIALL 250
Query: 182 REDETLDDLKQLSPEELLLRWVNYHLEKAGITKRITNFKEDIQDSEIYSHLLYQIAPSDK 361
R+ E+L+DL +LSPEELLLRW NYHLE+AG K I NF DI+DS+ Y ++L Q+AP K
Sbjct: 251 RDGESLEDLVKLSPEELLLRWANYHLEEAGCPK-INNFSSDIKDSKAYYNILNQVAP--K 307
Query: 362 RDEM-LPPVAI----LKNTDNMKRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLN 526
RDE +P + I ++ D++KRAE ML A + R F+ DV + KLN
Sbjct: 308 RDEEGIPAIPIDISGIREKDDLKRAECMLEQADRLGCRQFVTATDVV------RGNPKLN 361
Query: 527 LAFVANLFNTYPALIVD-----SXXXXXXXXXXXKTYRNWINSMGVTPYVKDLYSDXXXX 691
LA+VANLFN YPAL +T+RNW+NS+GV P V LY D
Sbjct: 362 LAYVANLFNKYPALKKPENQDIDWSSIEGETREERTFRNWMNSLGVNPRVNHLYVDLADA 421
Query: 692 XXXXXXXXXXQPGIVEWKKIVRVFDPK-KKIFQVLGNCAHVIECAKK-LQLSIVNLSADN 865
+ V+W K+ + PK + L NC + +E KK + S+V ++ +
Sbjct: 422 LVIFQLYEKIKVP-VDWDKVNKPPYPKLGSNMKKLENCNYAVELGKKEAKFSLVGIAGQD 480
Query: 866 IKDATPNLTLGLCFQMLR 919
+ + LTL L +Q++R
Sbjct: 481 LNEGNRTLTLALLWQLMR 498
Score = 45.1 bits (105), Expect = 3e-04
Identities = 42/150 (28%), Positives = 69/150 (46%), Gaps = 1/150 (0%)
Frame = +2
Query: 47 MVNIGSEDIEKGTKHLVLGLVWQVIRXXXXXXXXXXXXAELVALLREDETLDDLKQLSPE 226
+V I +D+ +G + L L L+WQ++R L E L D +++ +
Sbjct: 473 LVGIAGQDLNEGNRTLTLALLWQLMRRYT---------------LNILEDLGDGQKII-D 516
Query: 227 ELLLRWVNYHLEKAGITKRITNFKE-DIQDSEIYSHLLYQIAPSDKRDEMLPPVAILKNT 403
E +++WVN L +AG I+ FK+ I S L+ I P R ++L L +
Sbjct: 517 ETIVQWVNETLTQAG-KGTISGFKDGSISSSMPVLDLIDAIQPGSIRYDLLK-AEDLTDE 574
Query: 404 DNMKRAELMLGNASLIDARVFIEPEDVALV 493
+ A+ + A I ARV+ PED+ V
Sbjct: 575 KKLNNAKYAISMARKIGARVYALPEDLVEV 604
Score = 30.8 bits (68), Expect = 5.6
Identities = 15/52 (28%), Positives = 30/52 (57%), Gaps = 2/52 (3%)
Frame = +2
Query: 770 KKKI--FQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLTLGLCFQMLR 919
KKK+ F + N + A + +VN+ A+++K+ +L LGL +Q+++
Sbjct: 180 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGRQHLVLGLLWQVIK 231
>sp|P13796|PLSL_HUMAN L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P)
Length = 627
Score = 209 bits (533), Expect = 7e-54
Identities = 131/317 (41%), Positives = 179/317 (56%), Gaps = 11/317 (3%)
Frame = +2
Query: 2 NLCLAVNSAEAIGCCMVNIGSEDIEKGTKHLVLGLVWQVIRXXXXXXXXXXXXAELVALL 181
NL LA+NSA AIGC +VNIG+ED+++G +LVLGL+WQVI+ L+ALL
Sbjct: 193 NLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALIALL 252
Query: 182 REDETLDDLKQLSPEELLLRWVNYHLEKAGITKRITNFKEDIQDSEIYSHLLYQIAPSDK 361
RE E+L+DL +LSPEELLLRW NYHLE AG K I NF DI+DS+ Y HLL Q+AP
Sbjct: 253 REGESLEDLMKLSPEELLLRWANYHLENAGCNK-IGNFSTDIKDSKAYYHLLEQVAPKGD 311
Query: 362 RDEMLPPVAI----LKNTDNMKRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLNL 529
+E +P V I L+ D+++RAE ML A + R F+ DV + KLNL
Sbjct: 312 -EEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVV------RGNPKLNL 364
Query: 530 AFVANLFNTYPALIVD-----SXXXXXXXXXXXKTYRNWINSMGVTPYVKDLYSDXXXXX 694
AF+ANLFN YPAL +T+RNW+NS+GV P V LYSD
Sbjct: 365 AFIANLFNRYPALHKPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDLSDAL 424
Query: 695 XXXXXXXXXQPGIVEWKKIVRVFDPK-KKIFQVLGNCAHVIECAK-KLQLSIVNLSADNI 868
+ V+W ++ + PK + L NC + +E K + + S+V + ++
Sbjct: 425 VIFQLYEKIKVP-VDWNRVNKPPYPKLGGNMKKLENCNYAVELGKNQAKFSLVGIGGQDL 483
Query: 869 KDATPNLTLGLCFQMLR 919
+ LTL L +Q++R
Sbjct: 484 NEGNRTLTLALIWQLMR 500
Score = 48.1 bits (113), Expect = 3e-05
Identities = 39/158 (24%), Positives = 72/158 (45%), Gaps = 6/158 (3%)
Frame = +2
Query: 47 MVNIGSEDIEKGTKHLVLGLVWQVIRXXXXXXXXXXXXAELVALLREDETLDDLKQLSP- 223
+V IG +D+ +G + L L L+WQ++R TL+ L+++
Sbjct: 475 LVGIGGQDLNEGNRTLTLALIWQLMRRY---------------------TLNILEEIGGG 513
Query: 224 ----EELLLRWVNYHLEKAGITKRITNFKE-DIQDSEIYSHLLYQIAPSDKRDEMLPPVA 388
+++++ WVN L +A + I++FK+ I S L+ I P ++L
Sbjct: 514 QKVNDDIIVNWVNETLREAEKSSSISSFKDPKISTSLPVLDLIDAIQPGSINYDLL-KTE 572
Query: 389 ILKNTDNMKRAELMLGNASLIDARVFIEPEDVALVTQR 502
L + + + A+ + A I ARV+ PED+ V +
Sbjct: 573 NLNDDEKLNNAKYAISMARKIGARVYALPEDLVEVNPK 610
Score = 32.7 bits (73), Expect = 1.5
Identities = 16/52 (30%), Positives = 30/52 (57%), Gaps = 2/52 (3%)
Frame = +2
Query: 770 KKKI--FQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLTLGLCFQMLR 919
KKK+ F + N + A + +VN+ A+++K+ P L LGL +Q+++
Sbjct: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIK 233
>sp|Q14651|PLSI_HUMAN I-plastin (Intestine-specific plastin) (Plastin-1)
Length = 629
Score = 208 bits (530), Expect = 1e-53
Identities = 130/323 (40%), Positives = 175/323 (54%), Gaps = 17/323 (5%)
Frame = +2
Query: 2 NLCLAVNSAEAIGCCMVNIGSEDIEKGTKHLVLGLVWQVIRXXXXXXXXXXXXAELVALL 181
NL LA+NSA AIGC +VNIG+ D+++G HLVLGL+WQ+I+ L+ALL
Sbjct: 195 NLNLALNSASAIGCTVVNIGASDLKEGKPHLVLGLLWQIIKVGLFADIEISRNEALIALL 254
Query: 182 REDETLDDLKQLSPEELLLRWVNYHLEKAGITKRITNFKEDIQDSEIYSHLLYQIAPSDK 361
E E L++L +LSPEELLLRWVNYHL AG I+NF +DI+DS Y HLL QIAP
Sbjct: 255 NEGEELEELMKLSPEELLLRWVNYHLTNAG-WHTISNFSQDIKDSRAYFHLLNQIAPKGG 313
Query: 362 RDEMLPPVAI----LKNTDNMKRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLNL 529
D P +AI + T+++KRA LML A + + F+ P DV KLNL
Sbjct: 314 EDG--PAIAIDLSGINETNDLKRAGLMLQEADKLGCKQFVTPADVV------SGNPKLNL 365
Query: 530 AFVANLFNTYPALIVDS-----XXXXXXXXXXXKTYRNWINSMGVTPYVKDLYSDXXXXX 694
AFVANLFNTYP L + +T+RNW+NS+GV PY+ LYSD
Sbjct: 366 AFVANLFNTYPCLHKPNNNDIDMNLLEGESKEERTFRNWMNSLGVNPYINHLYSDLADAL 425
Query: 695 XXXXXXXXXQPGIVEWKKIVRVFDPKKKIFQVLG-------NCAHVIECAK-KLQLSIVN 850
+ V W + K + LG NC + +E K K + S+V
Sbjct: 426 VIFQLYEMIRVP-VNWSHV------NKPPYPALGGNMKKIENCNYAVELGKNKAKFSLVG 478
Query: 851 LSADNIKDATPNLTLGLCFQMLR 919
++ ++ + LTL L +Q++R
Sbjct: 479 IAGQDLNERNSTLTLALVWQLMR 501
Score = 53.1 bits (126), Expect = 1e-06
Identities = 42/150 (28%), Positives = 72/150 (48%), Gaps = 1/150 (0%)
Frame = +2
Query: 47 MVNIGSEDIEKGTKHLVLGLVWQVIRXXXXXXXXXXXXAELVALLREDETLDDLKQLSPE 226
+V I +D+ + L L LVWQ++R +++ L E E ++D
Sbjct: 476 LVGIAGQDLNERNSTLTLALVWQLMRRYTL---------NVLSDLGEGEKVND------- 519
Query: 227 ELLLRWVNYHLEKAGITKRITNFKE-DIQDSEIYSHLLYQIAPSDKRDEMLPPVAILKNT 403
E++++WVN L+ A I++FK+ I S L+ IAP+ R EM+ L +
Sbjct: 520 EIIIKWVNQTLKSANKKTSISSFKDKSISTSLPVLDLIDAIAPNAVRQEMIRR-ENLSDE 578
Query: 404 DNMKRAELMLGNASLIDARVFIEPEDVALV 493
D + A+ + A I AR++ P+D+ V
Sbjct: 579 DKLNNAKYAISVARKIGARIYALPDDLVEV 608
Score = 33.9 bits (76), Expect = 0.66
Identities = 16/52 (30%), Positives = 31/52 (59%), Gaps = 2/52 (3%)
Frame = +2
Query: 770 KKKI--FQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLTLGLCFQMLR 919
KKK+ F + N + A + ++VN+ A ++K+ P+L LGL +Q+++
Sbjct: 184 KKKLTPFTISENLNLALNSASAIGCTVVNIGASDLKEGKPHLVLGLLWQIIK 235
>sp|P54680|FIMB_DICDI Fimbrin
Length = 610
Score = 206 bits (524), Expect = 7e-53
Identities = 119/309 (38%), Positives = 172/309 (55%), Gaps = 3/309 (0%)
Frame = +2
Query: 2 NLCLAVNSAEAIGCCMVNIGSEDIEKGTKHLVLGLVWQVIRXXXXXXXXXXXXAELVALL 181
N L +NSA+AIGC +VNIG+ D+ +G HL++GL WQ+I+ EL LL
Sbjct: 189 NQVLCINSAKAIGCNVVNIGAGDLVEGRAHLIMGLTWQIIKIGLFARINLTNHPELYRLL 248
Query: 182 REDETLDDLKQLSPEELLLRWVNYHLEKAGITKRITNFKEDIQDSEIYSHLLYQIAPSDK 361
+ ET++DL +L EE+LLRW NYHL AG +R+ NF DI+DSE Y+ LL QIAP D
Sbjct: 249 HDGETIEDLLKLPVEEILLRWFNYHLAAAGSQRRVKNFSGDIKDSECYTILLKQIAPKDA 308
Query: 362 RDEMLPPVAILKNTDNMKRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLNLAFVA 541
E + L ++ +RA +L NA + + F++P+D+ Q KLNLAFVA
Sbjct: 309 GVE----TSALNISNLDQRAVKVLENADKLGCKKFLKPKDIVTGFQ------KLNLAFVA 358
Query: 542 NLFNTYPALIVDSXXXXXXXXXXXKTYRNWINSMGVTPYVKDLYSDXXXXXXXXXXXXXX 721
NLFNT+PAL KT+RNW+NS+GV P+V +LY
Sbjct: 359 NLFNTHPALEPVEDVVIIEETREEKTFRNWMNSLGVDPFVNNLYEGTYDGLILIQLFDKI 418
Query: 722 QPGIVEWKKIVRVFDPKKKI---FQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLT 892
PG+V+ KK+ + P K + + + NC + I+ K + S+V + N+ D LT
Sbjct: 419 YPGLVDHKKV--NYPPYKAMGAEMKKIENCNYAIQLGKDCKYSLVGIDGKNVYDKNKTLT 476
Query: 893 LGLCFQMLR 919
L + +Q++R
Sbjct: 477 LSILWQLMR 485
Score = 30.8 bits (68), Expect = 5.6
Identities = 41/171 (23%), Positives = 69/171 (40%), Gaps = 3/171 (1%)
Frame = +2
Query: 47 MVNIGSEDIEKGTKHLVLGLVWQVIRXXXXXXXXXXXXAELVALLREDETLDDLKQLSPE 226
+V I +++ K L L ++WQ++R L AL + + D
Sbjct: 460 LVGIDGKNVYDKNKTLTLSILWQLMRGHVISI--------LTALSGSGKPIADAD----- 506
Query: 227 ELLLRWVNYHLEKAGITKRITNFKEDIQDSEIYSHLLYQIAPSDKRDEMLPPVAILKN-- 400
++ N L AG K+I+ FK DS I + + R + P + +
Sbjct: 507 --IVNVANSKLSAAG-KKQISGFK----DSTISTGIPILDVIEAVRPGSVDPALVATSGS 559
Query: 401 -TDNMKRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLNLAFVANLF 550
DN+ A+L + A + A VF PED+ V + K+ L A+L+
Sbjct: 560 AEDNLLNAKLAVSTARKVGAVVFALPEDIVEV------KPKMVLTLFASLW 604
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,058,551
Number of Sequences: 369166
Number of extensions: 1626911
Number of successful extensions: 4642
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4355
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4567
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9366655350
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)