Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_L20
(918 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5R644|API5_PONPY Apoptosis inhibitor 5 (API-5) 166 1e-40
sp|Q9BZZ5|API5_HUMAN Apoptosis inhibitor 5 (API-5) (Fibrobl... 166 1e-40
sp|Q5ZMW3|API5_CHICK Apoptosis inhibitor 5 (API-5) 164 4e-40
sp|O35841|API5_MOUSE Apoptosis inhibitor 5 (API-5) (AAC-11) 163 5e-40
sp|P36112|YKZ6_YEAST Hypothetical 61.1 kDa protein in YPT52... 37 0.078
sp|Q6KC79|NIPBL_HUMAN Nipped-B-like protein (Delangin) (SCC... 36 0.13
sp|Q6KCD5|NPBL_MOUSE Nipped-B-like protein (Delangin homolo... 36 0.13
sp|Q12675|ATC4_YEAST Probable phospholipid-transporting ATP... 35 0.39
sp|P21555|NPY1R_RAT Neuropeptide Y receptor type 1 (NPY1-R)... 34 0.66
sp|Q04573|NPY1R_MOUSE Neuropeptide Y receptor type 1 (NPY1-R) 34 0.66
>sp|Q5R644|API5_PONPY Apoptosis inhibitor 5 (API-5)
Length = 504
Score = 166 bits (419), Expect = 1e-40
Identities = 107/278 (38%), Positives = 168/278 (60%), Gaps = 6/278 (2%)
Frame = +2
Query: 20 KVAYETILKGVNGEEKEKRLASQFIANFFKLFPQLYEESFNKLLDLCEDDNVVIRKQVIQ 199
K AY+ IL GV G KEKRLA+QFI FFK FP+L + + N LDLCED++V IR+Q I+
Sbjct: 25 KDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIK 84
Query: 200 YLSVIAKSVPDYIPKIADTLIQMLITDDNTEVSLIYSALNTVIKLDSKVALEAIFNQLIT 379
L A + +P++AD L Q+L TDD+ E +L+ +AL ++ K+D+K L +F+Q++
Sbjct: 85 ELPQFATG--ENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQIL- 141
Query: 380 QLDESNELINTFAFKYLNEKFSTEND--FKSEIETLIETHGTKLLTKLSGKDEFPLLIGI 553
+ +++ A K+L+ K T D E+E LI T K+L ++G +EF L + I
Sbjct: 142 ---QGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTG-EEFVLFMKI 197
Query: 554 LSSLKSNSTLVGRQKLLTEISEQAKLIGKVN-TNAKYTTLLLNC-KQAIKLVSKNVHADD 727
LS LKS T+ GRQ+L+ ++EQA L N ++ LL C +QA+ L SKNVH+
Sbjct: 198 LSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTR 257
Query: 728 LLMVLLDN-LANIVKLSSSAAELNL-YDLLRCLVELTN 835
+ + L N+ L++ L++ ++L+ L E+++
Sbjct: 258 FVTYFCEQVLPNLGTLTTPVEGLDIQLEVLKLLAEMSS 295
>sp|Q9BZZ5|API5_HUMAN Apoptosis inhibitor 5 (API-5) (Fibroblast growth factor
2-interacting factor) (FIF) (XAGL protein) (AAC-11)
Length = 510
Score = 166 bits (419), Expect = 1e-40
Identities = 107/278 (38%), Positives = 168/278 (60%), Gaps = 6/278 (2%)
Frame = +2
Query: 20 KVAYETILKGVNGEEKEKRLASQFIANFFKLFPQLYEESFNKLLDLCEDDNVVIRKQVIQ 199
K AY+ IL GV G KEKRLA+QFI FFK FP+L + + N LDLCED++V IR+Q I+
Sbjct: 25 KDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIK 84
Query: 200 YLSVIAKSVPDYIPKIADTLIQMLITDDNTEVSLIYSALNTVIKLDSKVALEAIFNQLIT 379
L A + +P++AD L Q+L TDD+ E +L+ +AL ++ K+D+K L +F+Q++
Sbjct: 85 ELPQFATG--ENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQIL- 141
Query: 380 QLDESNELINTFAFKYLNEKFSTEND--FKSEIETLIETHGTKLLTKLSGKDEFPLLIGI 553
+ +++ A K+L+ K T D E+E LI T K+L ++G +EF L + I
Sbjct: 142 ---QGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTG-EEFVLFMKI 197
Query: 554 LSSLKSNSTLVGRQKLLTEISEQAKLIGKVN-TNAKYTTLLLNC-KQAIKLVSKNVHADD 727
LS LKS T+ GRQ+L+ ++EQA L N ++ LL C +QA+ L SKNVH+
Sbjct: 198 LSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTR 257
Query: 728 LLMVLLDN-LANIVKLSSSAAELNL-YDLLRCLVELTN 835
+ + L N+ L++ L++ ++L+ L E+++
Sbjct: 258 FVTYFCEQVLPNLGTLTTPVEGLDIQLEVLKLLAEMSS 295
>sp|Q5ZMW3|API5_CHICK Apoptosis inhibitor 5 (API-5)
Length = 523
Score = 164 bits (414), Expect = 4e-40
Identities = 105/278 (37%), Positives = 167/278 (60%), Gaps = 6/278 (2%)
Frame = +2
Query: 20 KVAYETILKGVNGEEKEKRLASQFIANFFKLFPQLYEESFNKLLDLCEDDNVVIRKQVIQ 199
K AY+ IL GV G KEKRLA+QFI FFK FP+L + + N LDLCED++V IR+Q I+
Sbjct: 25 KDAYQVILDGVKGGAKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIK 84
Query: 200 YLSVIAKSVPDYIPKIADTLIQMLITDDNTEVSLIYSALNTVIKLDSKVALEAIFNQLIT 379
L A D +P++AD L Q+L +DD+ E +L+ +AL ++ K+D+K L +F+Q++
Sbjct: 85 ELPQFATG--DNLPRVADILTQLLQSDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQIL- 141
Query: 380 QLDESNELINTFAFKYLNEKFST--ENDFKSEIETLIETHGTKLLTKLSGKDEFPLLIGI 553
+ +++ A K+L+ K T E E+E I K+L ++G +EF L + I
Sbjct: 142 ---QGEDIVRERAIKFLSTKLKTLPEEVLTKEVEEFILAESKKVLEDVTG-EEFVLFMKI 197
Query: 554 LSSLKSNSTLVGRQKLLTEISEQAKLIGKVN-TNAKYTTLLLNC-KQAIKLVSKNVHADD 727
LS LKS T+ GRQ+L+ ++EQA L N ++ LL C +QA+ L SKNVH+
Sbjct: 198 LSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTK 257
Query: 728 LLMVLLDN-LANIVKLSSSAAELNL-YDLLRCLVELTN 835
+ ++ L N+ L++ L++ ++L+ L E+++
Sbjct: 258 FVTYFCEHVLPNLSALTTPVEGLDIQLEVLKLLAEMSS 295
>sp|O35841|API5_MOUSE Apoptosis inhibitor 5 (API-5) (AAC-11)
Length = 504
Score = 163 bits (413), Expect = 5e-40
Identities = 106/278 (38%), Positives = 167/278 (60%), Gaps = 6/278 (2%)
Frame = +2
Query: 20 KVAYETILKGVNGEEKEKRLASQFIANFFKLFPQLYEESFNKLLDLCEDDNVVIRKQVIQ 199
K AY+ IL GV G KEKRLA+QFI FFK FP+L + + N LDLCED++V IR+Q I+
Sbjct: 25 KDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIK 84
Query: 200 YLSVIAKSVPDYIPKIADTLIQMLITDDNTEVSLIYSALNTVIKLDSKVALEAIFNQLIT 379
L A + +P++AD L Q+L TDD+ E +L+ +AL ++ K+D+K L +F+Q++
Sbjct: 85 ELPQFATG--ENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQIL- 141
Query: 380 QLDESNELINTFAFKYLNEKFSTEND--FKSEIETLIETHGTKLLTKLSGKDEFPLLIGI 553
+ +++ A K+L+ K T D E+E LI T K+L ++G +EF L + I
Sbjct: 142 ---QGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTG-EEFVLFMKI 197
Query: 554 LSSLKSNSTLVGRQKLLTEISEQAKLIGKVN-TNAKYTTLLLNC-KQAIKLVSKNVHADD 727
LS LKS T+ GRQ+L+ ++EQA L + ++ LL C +QA+ L SKNVH+
Sbjct: 198 LSGLKSLQTVSGRQQLVELVAEQADLEQAFSPSDPDCVDRLLQCTRQAVPLFSKNVHSTR 257
Query: 728 LLMVLLDN-LANIVKLSSSAAELNL-YDLLRCLVELTN 835
+ + L N+ L++ L++ ++L L E+++
Sbjct: 258 FVTYFCEQVLPNLSTLTTPVEGLDIQLEVLNLLAEMSS 295
>sp|P36112|YKZ6_YEAST Hypothetical 61.1 kDa protein in YPT52-DBP7 intergenic region
Length = 540
Score = 37.0 bits (84), Expect = 0.078
Identities = 45/225 (20%), Positives = 96/225 (42%), Gaps = 3/225 (1%)
Frame = +2
Query: 116 PQLYE--ESFNKLLDLCEDDNVVIRKQVIQYLSVIAKSVPDYIPKIADTLIQMLITDDNT 289
PQL E S N L++ D N+ I + + +++ + ++ +TL + L
Sbjct: 144 PQLKEIIGSLNDLINSLNDSNLSIPESEFNSIKKSNQNMLTNLSQLNETLKEALSNYMIQ 203
Query: 290 EVSLIYSALNTVIKLDSKVALEAIFNQLITQLDESNELINTFAFKYLNEKFSTENDFKSE 469
S + + LNT + + + + L+ ++DE E + K L EK K+
Sbjct: 204 RTSEVITELNTQYENSKREFEKNLQKNLLQEVDEFKENLTKQKDKELEEK------LKAN 257
Query: 470 IETLIETHGTKL-LTKLSGKDEFPLLIGILSSLKSNSTLVGRQKLLTEISEQAKLIGKVN 646
E L H ++ L ++ EF +I + N L +++ +E+++ +K I + +
Sbjct: 258 EELLQAKHANEVGLLSITQVKEFNKIIKDKIEKERNGRLAHLEEINSEVNDLSKSIDRSS 317
Query: 647 TNAKYTTLLLNCKQAIKLVSKNVHADDLLMVLLDNLANIVKLSSS 781
L+ + + ++ ++L V +D + +KL S+
Sbjct: 318 KILSKNEALVQLTFQVDEIKSRINNNNLPDVNIDKELSRLKLLSN 362
>sp|Q6KC79|NIPBL_HUMAN Nipped-B-like protein (Delangin) (SCC2 homolog)
Length = 2804
Score = 36.2 bits (82), Expect = 0.13
Identities = 22/81 (27%), Positives = 42/81 (51%), Gaps = 5/81 (6%)
Frame = +2
Query: 44 KGVNGEEKE-----KRLASQFIANFFKLFPQLYEESFNKLLDLCEDDNVVIRKQVIQYLS 208
+GV+G + + A + + F PQL E+ ++ L++ D + +RK+VI+ L
Sbjct: 1814 RGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILR 1873
Query: 209 VIAKSVPDYIPKIADTLIQML 271
I P + PKI + ++M+
Sbjct: 1874 DICIEQPTF-PKITEMCVKMI 1893
>sp|Q6KCD5|NPBL_MOUSE Nipped-B-like protein (Delangin homolog) (SCC2 homolog)
Length = 2798
Score = 36.2 bits (82), Expect = 0.13
Identities = 22/81 (27%), Positives = 42/81 (51%), Gaps = 5/81 (6%)
Frame = +2
Query: 44 KGVNGEEKE-----KRLASQFIANFFKLFPQLYEESFNKLLDLCEDDNVVIRKQVIQYLS 208
+GV+G + + A + + F PQL E+ ++ L++ D + +RK+VI+ L
Sbjct: 1808 RGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILR 1867
Query: 209 VIAKSVPDYIPKIADTLIQML 271
I P + PKI + ++M+
Sbjct: 1868 DICIEQPTF-PKITEMCVKMI 1887
>sp|Q12675|ATC4_YEAST Probable phospholipid-transporting ATPase DNF2
Length = 1612
Score = 34.7 bits (78), Expect = 0.39
Identities = 27/125 (21%), Positives = 58/125 (46%), Gaps = 2/125 (1%)
Frame = +2
Query: 128 EESFNKLLDLCEDDNVVIRKQVIQYLSVIAKSVPDYIPKIADTLIQM-LITDDNTEVSLI 304
EE +K+ D+ E + +++ I+ + VPD I +A+ I++ ++T D E ++
Sbjct: 984 EEELDKVTDVIERELILLGGTAIE--DRLQDGVPDSIALLAEAGIKLWVLTGDKVETAIN 1041
Query: 305 YSALNTVIKLDSKVALEAIFNQLITQL-DESNELINTFAFKYLNEKFSTENDFKSEIETL 481
V+ D ++ + + + + + +++N KYL EKF + E++
Sbjct: 1042 IGFSCNVLNNDMELLVVKASGEDVEEFGSDPIQVVNNLVTKYLREKFGMSGS-EEELKEA 1100
Query: 482 IETHG 496
HG
Sbjct: 1101 KREHG 1105
>sp|P21555|NPY1R_RAT Neuropeptide Y receptor type 1 (NPY1-R) (FC5)
Length = 382
Score = 33.9 bits (76), Expect = 0.66
Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Frame = -1
Query: 633 INLACSDISVSNFCRPTRVEFDLSDDKIPINNGNSSFPESL--VNNFVPCVSIRVSISDL 460
+NL+ SD+ V+ C P + L D + F E++ +N FV CVSI VSI L
Sbjct: 79 VNLSFSDLLVAVMCLPFTFVYTLMDHWV--------FGETMCKLNPFVQCVSITVSIFSL 130
Query: 459 KSFSVE 442
+VE
Sbjct: 131 VLIAVE 136
>sp|Q04573|NPY1R_MOUSE Neuropeptide Y receptor type 1 (NPY1-R)
Length = 382
Score = 33.9 bits (76), Expect = 0.66
Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Frame = -1
Query: 633 INLACSDISVSNFCRPTRVEFDLSDDKIPINNGNSSFPESL--VNNFVPCVSIRVSISDL 460
+NL+ SD+ V+ C P + L D + F E++ +N FV CVSI VSI L
Sbjct: 79 VNLSFSDLLVAVMCLPFTFVYTLMDHWV--------FGETMCKLNPFVQCVSITVSIFSL 130
Query: 459 KSFSVE 442
+VE
Sbjct: 131 VLIAVE 136
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,958,822
Number of Sequences: 369166
Number of extensions: 1807118
Number of successful extensions: 5416
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5159
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5394
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9366655350
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)