Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_L15
(853 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P13607|ATNA_DROME Sodium/potassium-transporting ATPase a... 350 2e-96
sp|P30714|AT1A1_BUFMA Sodium/potassium-transporting ATPase ... 344 2e-94
sp|P09572|AT1A1_CHICK Sodium/potassium-transporting ATPase ... 343 5e-94
sp|P50997|AT1A1_CANFA Sodium/potassium-transporting ATPase ... 342 6e-94
sp|P05023|AT1A1_HUMAN Sodium/potassium-transporting ATPase ... 341 1e-93
sp|P50993|AT1A2_HUMAN Sodium/potassium-transporting ATPase ... 341 2e-93
sp|P06686|AT1A2_RAT Sodium/potassium-transporting ATPase al... 340 2e-93
sp|P24798|AT1A3_CHICK Sodium/potassium-transporting ATPase ... 340 2e-93
sp|P18907|AT1A1_HORSE Sodium/potassium-transporting ATPase ... 340 3e-93
sp|P06687|AT1A3_RAT Sodium/potassium-transporting ATPase al... 340 3e-93
>sp|P13607|ATNA_DROME Sodium/potassium-transporting ATPase alpha chain (Sodium pump)
(Na+/K+ ATPase)
Length = 1041
Score = 350 bits (899), Expect = 2e-96
Identities = 165/221 (74%), Positives = 185/221 (83%)
Frame = +1
Query: 1 TITILCIDLGTDMVPAISLAYEEAESDIMKRKPRDPKHDKLVNERLISMAYGQIGMIQAS 180
T+TILCIDLGTDMVPAISLAYE AE+DIMKR PRDP +DKLVN RLISMAYGQIGMIQA+
Sbjct: 822 TVTILCIDLGTDMVPAISLAYEHAEADIMKRPPRDPFNDKLVNSRLISMAYGQIGMIQAA 881
Query: 181 GGFFVYFVIMAEQGFWPSRLLGLRKEWDSAAVNDLADSYGQEWTFEQRKKLEYTCHTAFF 360
GFFVYFVIMAE GF P +L G+RK WDS AVNDL DSYGQEWT+ RK LEYTCHTAFF
Sbjct: 882 AGFFVYFVIMAENGFLPKKLFGIRKMWDSKAVNDLTDSYGQEWTYRDRKTLEYTCHTAFF 941
Query: 361 VSIVIVQWTDLMICKTRRNSIFQQGMWNHQMTFGLFFETTLAAFLTYCPGLDVALKMQPL 540
+SIV+VQW DL+ICKTRRNSIFQQGM N + FGL FET LAAFL+YCPG++ L+M PL
Sbjct: 942 ISIVVVQWADLIICKTRRNSIFQQGMRNWALNFGLVFETVLAAFLSYCPGMEKGLRMYPL 1001
Query: 541 RFTWWLPAIPFSASIFIYDEVRKFLLRKWKNGSWLENETYY 663
+ WW PAIPF+ +IFIYDE R+F LR+ G WLE ETYY
Sbjct: 1002 KLVWWFPAIPFALAIFIYDETRRFYLRR-NPGGWLEQETYY 1041
>sp|P30714|AT1A1_BUFMA Sodium/potassium-transporting ATPase alpha-1 chain precursor (Sodium
pump 1) (Na+/K+ ATPase 1)
Length = 1023
Score = 344 bits (882), Expect = 2e-94
Identities = 164/221 (74%), Positives = 188/221 (85%)
Frame = +1
Query: 1 TITILCIDLGTDMVPAISLAYEEAESDIMKRKPRDPKHDKLVNERLISMAYGQIGMIQAS 180
T+TILCIDLGTDMVPAISLAYE+AESDIMKR+PR+PK DKLVNERLISMAYGQIGMIQA
Sbjct: 804 TVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKKDKLVNERLISMAYGQIGMIQAL 863
Query: 181 GGFFVYFVIMAEQGFWPSRLLGLRKEWDSAAVNDLADSYGQEWTFEQRKKLEYTCHTAFF 360
GGFF YFVI+AE GF PS LLG+R W+ VND+ DSYGQ+WT+EQRK +E+TCHTAFF
Sbjct: 864 GGFFAYFVILAENGFLPSTLLGIRVAWEDRYVNDVEDSYGQQWTYEQRKIVEFTCHTAFF 923
Query: 361 VSIVIVQWTDLMICKTRRNSIFQQGMWNHQMTFGLFFETTLAAFLTYCPGLDVALKMQPL 540
VSIV+VQW DL+ICKTRRNS+FQQGM N + FGLF ET LAAFL+YCPG+DVAL+M PL
Sbjct: 924 VSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYPL 983
Query: 541 RFTWWLPAIPFSASIFIYDEVRKFLLRKWKNGSWLENETYY 663
+ TWW A P+S IFIYDEVRK +LR+ G W+E ETYY
Sbjct: 984 KPTWWFCAFPYSLLIFIYDEVRKLILRR-SPGGWVEKETYY 1023
>sp|P09572|AT1A1_CHICK Sodium/potassium-transporting ATPase alpha-1 chain precursor (Sodium
pump 1) (Na+/K+ ATPase 1)
Length = 1021
Score = 343 bits (879), Expect = 5e-94
Identities = 162/221 (73%), Positives = 188/221 (85%)
Frame = +1
Query: 1 TITILCIDLGTDMVPAISLAYEEAESDIMKRKPRDPKHDKLVNERLISMAYGQIGMIQAS 180
T TILCIDLGTDMVPAISLAYE+AESDIMKR+PR+PK DKLVNERLISMAYGQIGMIQA
Sbjct: 802 TCTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQAL 861
Query: 181 GGFFVYFVIMAEQGFWPSRLLGLRKEWDSAAVNDLADSYGQEWTFEQRKKLEYTCHTAFF 360
GGFF YFVIMAE GF PS L+G+R +WD +ND+ DSYGQ+WTFEQRK +E+TCHTAFF
Sbjct: 862 GGFFTYFVIMAENGFLPSGLVGIRLQWDDRWINDVEDSYGQQWTFEQRKIVEFTCHTAFF 921
Query: 361 VSIVIVQWTDLMICKTRRNSIFQQGMWNHQMTFGLFFETTLAAFLTYCPGLDVALKMQPL 540
VSIV+VQW DL+ICKTRRNS+FQQGM N + FGLF ET LAAFL+YCPG+DVAL+M PL
Sbjct: 922 VSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYPL 981
Query: 541 RFTWWLPAIPFSASIFIYDEVRKFLLRKWKNGSWLENETYY 663
+ TWW A P+S IF+YDE+RK ++R+ G W+E ETYY
Sbjct: 982 KPTWWFCAFPYSLLIFLYDEIRKLIIRR-NPGGWVERETYY 1021
>sp|P50997|AT1A1_CANFA Sodium/potassium-transporting ATPase alpha-1 chain precursor (Sodium
pump 1) (Na+/K+ ATPase 1)
Length = 1021
Score = 342 bits (878), Expect = 6e-94
Identities = 161/221 (72%), Positives = 189/221 (85%)
Frame = +1
Query: 1 TITILCIDLGTDMVPAISLAYEEAESDIMKRKPRDPKHDKLVNERLISMAYGQIGMIQAS 180
T+TILCIDLGTDMVPAISLAYE+AESDIMKR+PR+PK DKLVNERLISMAYGQIGMIQA
Sbjct: 802 TVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQAL 861
Query: 181 GGFFVYFVIMAEQGFWPSRLLGLRKEWDSAAVNDLADSYGQEWTFEQRKKLEYTCHTAFF 360
GGFF YFVI+AE GF P+ LLGLR +WD +ND+ DSYGQ+WT+EQRK +E+TCHTAFF
Sbjct: 862 GGFFTYFVILAENGFLPTHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFF 921
Query: 361 VSIVIVQWTDLMICKTRRNSIFQQGMWNHQMTFGLFFETTLAAFLTYCPGLDVALKMQPL 540
VSIV+VQW DL+ICKTRRNS+FQQGM N + FGLF ET LAAFL+YCPG+ VAL+M PL
Sbjct: 922 VSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPL 981
Query: 541 RFTWWLPAIPFSASIFIYDEVRKFLLRKWKNGSWLENETYY 663
+ TWW A P+S IF+YDEVRK ++R+ + G W+E ETYY
Sbjct: 982 KPTWWFCAFPYSLLIFVYDEVRKLIIRR-RPGGWVEKETYY 1021
>sp|P05023|AT1A1_HUMAN Sodium/potassium-transporting ATPase alpha-1 chain precursor (Sodium
pump 1) (Na+/K+ ATPase 1)
Length = 1023
Score = 341 bits (875), Expect = 1e-93
Identities = 161/221 (72%), Positives = 188/221 (85%)
Frame = +1
Query: 1 TITILCIDLGTDMVPAISLAYEEAESDIMKRKPRDPKHDKLVNERLISMAYGQIGMIQAS 180
T+TILCIDLGTDMVPAISLAYE+AESDIMKR+PR+PK DKLVNERLISMAYGQIGMIQA
Sbjct: 804 TVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQAL 863
Query: 181 GGFFVYFVIMAEQGFWPSRLLGLRKEWDSAAVNDLADSYGQEWTFEQRKKLEYTCHTAFF 360
GGFF YFVI+AE GF P LLGLR +WD +ND+ DSYGQ+WT+EQRK +E+TCHTAFF
Sbjct: 864 GGFFTYFVILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFF 923
Query: 361 VSIVIVQWTDLMICKTRRNSIFQQGMWNHQMTFGLFFETTLAAFLTYCPGLDVALKMQPL 540
VSIV+VQW DL+ICKTRRNS+FQQGM N + FGLF ET LAAFL+YCPG+ VAL+M PL
Sbjct: 924 VSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPL 983
Query: 541 RFTWWLPAIPFSASIFIYDEVRKFLLRKWKNGSWLENETYY 663
+ TWW A P+S IF+YDEVRK ++R+ + G W+E ETYY
Sbjct: 984 KPTWWFCAFPYSLLIFVYDEVRKLIIRR-RPGGWVEKETYY 1023
>sp|P50993|AT1A2_HUMAN Sodium/potassium-transporting ATPase alpha-2 chain precursor (Sodium
pump 2) (Na+/K+ ATPase 2)
Length = 1020
Score = 341 bits (874), Expect = 2e-93
Identities = 162/221 (73%), Positives = 186/221 (84%)
Frame = +1
Query: 1 TITILCIDLGTDMVPAISLAYEEAESDIMKRKPRDPKHDKLVNERLISMAYGQIGMIQAS 180
T+TILCIDLGTDMVPAISLAYE AESDIMKR+PR+ + DKLVNERLISMAYGQIGMIQA
Sbjct: 801 TVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQAL 860
Query: 181 GGFFVYFVIMAEQGFWPSRLLGLRKEWDSAAVNDLADSYGQEWTFEQRKKLEYTCHTAFF 360
GGFF YFVI+AE GF PSRLLG+R +WD +NDL DSYGQEWT+EQRK +E+TCHTAFF
Sbjct: 861 GGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFF 920
Query: 361 VSIVIVQWTDLMICKTRRNSIFQQGMWNHQMTFGLFFETTLAAFLTYCPGLDVALKMQPL 540
SIV+VQW DL+ICKTRRNS+FQQGM N + FGL ET LAAFL+YCPG+ VAL+M PL
Sbjct: 921 ASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPL 980
Query: 541 RFTWWLPAIPFSASIFIYDEVRKFLLRKWKNGSWLENETYY 663
+ TWW A P+S IFIYDEVRK +LR++ G W+E ETYY
Sbjct: 981 KVTWWFCAFPYSLLIFIYDEVRKLILRRYP-GGWVEKETYY 1020
>sp|P06686|AT1A2_RAT Sodium/potassium-transporting ATPase alpha-2 chain precursor (Sodium
pump 2) (Na+/K+ ATPase 2) (Alpha(+))
sp|Q6PIE5|AT1A2_MOUSE Sodium/potassium-transporting ATPase alpha-2 chain precursor (Sodium
pump 2) (Na+/K+ ATPase 2) (Alpha(+))
Length = 1020
Score = 340 bits (873), Expect = 2e-93
Identities = 162/221 (73%), Positives = 185/221 (83%)
Frame = +1
Query: 1 TITILCIDLGTDMVPAISLAYEEAESDIMKRKPRDPKHDKLVNERLISMAYGQIGMIQAS 180
T+TILCIDLGTDMVPAISLAYE AESDIMKR+PR+ + DKLVNERLISMAYGQIGMIQA
Sbjct: 801 TVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQAL 860
Query: 181 GGFFVYFVIMAEQGFWPSRLLGLRKEWDSAAVNDLADSYGQEWTFEQRKKLEYTCHTAFF 360
GGFF YFVI+AE GF PSRLLG+R +WD NDL DSYGQEWT+EQRK +E+TCHTAFF
Sbjct: 861 GGFFTYFVILAENGFLPSRLLGIRLDWDDRTTNDLEDSYGQEWTYEQRKVVEFTCHTAFF 920
Query: 361 VSIVIVQWTDLMICKTRRNSIFQQGMWNHQMTFGLFFETTLAAFLTYCPGLDVALKMQPL 540
SIV+VQW DL+ICKTRRNS+FQQGM N + FGL ET LAAFL+YCPG+ VAL+M PL
Sbjct: 921 ASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPL 980
Query: 541 RFTWWLPAIPFSASIFIYDEVRKFLLRKWKNGSWLENETYY 663
+ TWW A P+S IFIYDEVRK +LR++ G W+E ETYY
Sbjct: 981 KVTWWFCAFPYSLLIFIYDEVRKLILRRYP-GGWVEKETYY 1020
>sp|P24798|AT1A3_CHICK Sodium/potassium-transporting ATPase alpha-3 chain (Sodium pump 3)
(Na+/K+ ATPase 3) (Alpha(III))
Length = 1010
Score = 340 bits (873), Expect = 2e-93
Identities = 161/221 (72%), Positives = 187/221 (84%)
Frame = +1
Query: 1 TITILCIDLGTDMVPAISLAYEEAESDIMKRKPRDPKHDKLVNERLISMAYGQIGMIQAS 180
TITILCIDLGTDMVPAISLAYE AESDIMKR+PR+P+ DKLVNERLISMAYGQIGMIQA
Sbjct: 791 TITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRSDKLVNERLISMAYGQIGMIQAL 850
Query: 181 GGFFVYFVIMAEQGFWPSRLLGLRKEWDSAAVNDLADSYGQEWTFEQRKKLEYTCHTAFF 360
GGFF YFVI+AE GF PS L+G+R WD +NDL DSYGQ+WT+EQRK +E+TCHTAFF
Sbjct: 851 GGFFSYFVILAENGFLPSCLVGIRLSWDDRTINDLEDSYGQQWTYEQRKVVEFTCHTAFF 910
Query: 361 VSIVIVQWTDLMICKTRRNSIFQQGMWNHQMTFGLFFETTLAAFLTYCPGLDVALKMQPL 540
VSIV+VQW DL+ICKTRRNS+FQQGM N + FGLF ET LAAFL+YCPG+DVAL+M PL
Sbjct: 911 VSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYPL 970
Query: 541 RFTWWLPAIPFSASIFIYDEVRKFLLRKWKNGSWLENETYY 663
+ +WW A P+S IF+YDE+RK +LR+ G W+E ETYY
Sbjct: 971 KPSWWFCAFPYSFLIFVYDEIRKLILRR-NPGGWVEKETYY 1010
>sp|P18907|AT1A1_HORSE Sodium/potassium-transporting ATPase alpha-1 chain precursor (Sodium
pump 1) (Na+/K+ ATPase 1)
Length = 1021
Score = 340 bits (872), Expect = 3e-93
Identities = 161/221 (72%), Positives = 188/221 (85%)
Frame = +1
Query: 1 TITILCIDLGTDMVPAISLAYEEAESDIMKRKPRDPKHDKLVNERLISMAYGQIGMIQAS 180
T+TILCIDLGTDMVPAISLAYE+AESDIMKR+PR+P+ DKLVNERLISMAYGQIGMIQA
Sbjct: 802 TVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPQTDKLVNERLISMAYGQIGMIQAL 861
Query: 181 GGFFVYFVIMAEQGFWPSRLLGLRKEWDSAAVNDLADSYGQEWTFEQRKKLEYTCHTAFF 360
GGFF YFVI+AE GF P LLGLR +WD VND+ DSYGQ+WT+EQRK +E+TCHTAFF
Sbjct: 862 GGFFTYFVILAENGFLPIHLLGLRVDWDDRWVNDVEDSYGQQWTYEQRKIVEFTCHTAFF 921
Query: 361 VSIVIVQWTDLMICKTRRNSIFQQGMWNHQMTFGLFFETTLAAFLTYCPGLDVALKMQPL 540
VSIV+VQW DL+ICKTRRNS+FQQGM N + FGLF ET LAAFL+YCPG+ VAL+M PL
Sbjct: 922 VSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPL 981
Query: 541 RFTWWLPAIPFSASIFIYDEVRKFLLRKWKNGSWLENETYY 663
+ TWW A P+S IF+YDEVRK ++R+ + G W+E ETYY
Sbjct: 982 KPTWWFCAFPYSLLIFVYDEVRKLIIRR-RPGGWVEKETYY 1021
>sp|P06687|AT1A3_RAT Sodium/potassium-transporting ATPase alpha-3 chain (Sodium pump 3)
(Na+/K+ ATPase 3) (Alpha(III))
sp|Q6PIC6|AT1A3_MOUSE Sodium/potassium-transporting ATPase alpha-3 chain (Sodium pump 3)
(Na+/K+ ATPase 3) (Alpha(III))
Length = 1013
Score = 340 bits (872), Expect = 3e-93
Identities = 161/221 (72%), Positives = 186/221 (84%)
Frame = +1
Query: 1 TITILCIDLGTDMVPAISLAYEEAESDIMKRKPRDPKHDKLVNERLISMAYGQIGMIQAS 180
TITILCIDLGTDMVPAISLAYE AESDIMKR+PR+P+ DKLVNERLISMAYGQIGMIQA
Sbjct: 794 TITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQAL 853
Query: 181 GGFFVYFVIMAEQGFWPSRLLGLRKEWDSAAVNDLADSYGQEWTFEQRKKLEYTCHTAFF 360
GGFF YFVI+AE GF P L+G+R WD VNDL DSYGQ+WT+EQRK +E+TCHTAFF
Sbjct: 854 GGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEFTCHTAFF 913
Query: 361 VSIVIVQWTDLMICKTRRNSIFQQGMWNHQMTFGLFFETTLAAFLTYCPGLDVALKMQPL 540
VSIV+VQW DL+ICKTRRNS+FQQGM N + FGLF ET LAAFL+YCPG+DVAL+M PL
Sbjct: 914 VSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYPL 973
Query: 541 RFTWWLPAIPFSASIFIYDEVRKFLLRKWKNGSWLENETYY 663
+ +WW A P+S IF+YDE+RK +LR+ G W+E ETYY
Sbjct: 974 KPSWWFCAFPYSFLIFVYDEIRKLILRR-NPGGWVEKETYY 1013
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 101,886,573
Number of Sequences: 369166
Number of extensions: 2114336
Number of successful extensions: 4337
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4137
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4281
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8390082510
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)