Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_019_K10 (374 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9NWZ5|UCKL1_HUMAN Uridine/cytidine kinase-like 1 129 2e-30 sp|Q91YL3|UCKL1_MOUSE Uridine/cytidine kinase-like 1 128 4e-30 sp|P27515|URK1_YEAST Uridine kinase (Uridine monophosphokin... 79 2e-15 sp|Q9HA47|UCK1_HUMAN Uridine-cytidine kinase 1 (UCK 1) (Uri... 76 2e-14 sp|P52623|UCK1_MOUSE Uridine-cytidine kinase 1 (UCK 1) (Uri... 76 3e-14 sp|Q9BZX2|UCK2_HUMAN Uridine-cytidine kinase 2 (UCK 2) (Uri... 73 2e-13 sp|Q99PM9|UCK2_MOUSE Uridine-cytidine kinase 2 (UCK 2) (Uri... 72 3e-13 sp|Q9VC99|UCK_DROME Probable uridine-cytidine kinase (UCK) ... 71 9e-13 sp|Q17413|UCK_CAEEL Probable uridine-cytidine kinase (UCK) ... 69 4e-12 sp|Q6G8V8|URK_STAAS Uridine kinase (Uridine monophosphokina... 66 2e-11
>sp|Q9NWZ5|UCKL1_HUMAN Uridine/cytidine kinase-like 1 Length = 548 Score = 129 bits (324), Expect = 2e-30 Identities = 62/94 (65%), Positives = 74/94 (78%), Gaps = 1/94 (1%) Frame = +1 Query: 88 KRTIYTAGRPPWYTADG-QLKEPFVIGICGGSASGKTTVANTIIENLNIPWVSLVCMDSF 264 KRTIYTAGRPPWY G Q KE F IG+ GGSASGKTTVA IIE L++PWV L+ MDSF Sbjct: 76 KRTIYTAGRPPWYNEHGTQSKEAFAIGLGGGSASGKTTVARMIIEALDVPWVVLLSMDSF 135 Query: 265 YKVLSADEKLEASKSNYNFDHPSAFDIDLIVQTL 366 YKVL+ ++ +A+ +N+NFDHP AFD DLI+ TL Sbjct: 136 YKVLTEQQQEQAAHNNFNFDHPDAFDFDLIISTL 169
>sp|Q91YL3|UCKL1_MOUSE Uridine/cytidine kinase-like 1 Length = 548 Score = 128 bits (322), Expect = 4e-30 Identities = 62/94 (65%), Positives = 74/94 (78%), Gaps = 1/94 (1%) Frame = +1 Query: 88 KRTIYTAGRPPWYTADG-QLKEPFVIGICGGSASGKTTVANTIIENLNIPWVSLVCMDSF 264 KRTIYTAGRPPWY G Q KE F IG+ GGSASGKTTVA IIE L++PWV L+ MDSF Sbjct: 76 KRTIYTAGRPPWYNEHGTQSKEAFAIGLGGGSASGKTTVARMIIEALDVPWVVLLSMDSF 135 Query: 265 YKVLSADEKLEASKSNYNFDHPSAFDIDLIVQTL 366 YKVL+ ++ +A+ +N+NFDHP AFD DLI+ TL Sbjct: 136 YKVLTQQQQEQAACNNFNFDHPDAFDFDLIISTL 169
>sp|P27515|URK1_YEAST Uridine kinase (Uridine monophosphokinase) Length = 501 Score = 79.3 bits (194), Expect = 2e-15 Identities = 34/85 (40%), Positives = 55/85 (64%) Frame = +1 Query: 115 PPWYTADGQLKEPFVIGICGGSASGKTTVANTIIENLNIPWVSLVCMDSFYKVLSADEKL 294 PPW T P++IGI G S SGKT+VA I+ ++N+PW L+ +D+FY L +++ Sbjct: 51 PPWTT-------PYIIGIGGASGSGKTSVAAKIVSSINVPWTVLISLDNFYNPLGPEDRA 103 Query: 295 EASKSNYNFDHPSAFDIDLIVQTLI 369 A K+ Y+FD P+A ++DL + ++ Sbjct: 104 RAFKNEYDFDEPNAINLDLAYKCIL 128
>sp|Q9HA47|UCK1_HUMAN Uridine-cytidine kinase 1 (UCK 1) (Uridine monophosphokinase 1) (Cytidine monophosphokinase 1) Length = 277 Score = 76.3 bits (186), Expect = 2e-14 Identities = 41/86 (47%), Positives = 55/86 (63%), Gaps = 7/86 (8%) Frame = +1 Query: 130 ADGQLKEPFVIGICGGSASGKTTVANTIIENLNIPWVS-------LVCMDSFYKVLSADE 288 AD + PF+IG+ GG+ASGK+TV I+E L V ++ D FYKVL+A++ Sbjct: 16 ADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQ 75 Query: 289 KLEASKSNYNFDHPSAFDIDLIVQTL 366 K +A K YNFDHP AFD DL+ +TL Sbjct: 76 KAKALKGQYNFDHPDAFDNDLMHRTL 101
>sp|P52623|UCK1_MOUSE Uridine-cytidine kinase 1 (UCK 1) (Uridine monophosphokinase 1) (Cytidine monophosphokinase 1) Length = 277 Score = 75.9 bits (185), Expect = 3e-14 Identities = 41/86 (47%), Positives = 54/86 (62%), Gaps = 7/86 (8%) Frame = +1 Query: 130 ADGQLKEPFVIGICGGSASGKTTVANTIIENLNIPWVS-------LVCMDSFYKVLSADE 288 AD PF+IG+ GG+ASGK+TV I+E L V ++ D FYKVL+A++ Sbjct: 16 ADRPQPRPFLIGVSGGTASGKSTVCEKIMELLGQNEVDRRQRKLVILSQDCFYKVLTAEQ 75 Query: 289 KLEASKSNYNFDHPSAFDIDLIVQTL 366 K +A K YNFDHP AFD DL+ +TL Sbjct: 76 KAKALKGQYNFDHPDAFDNDLMHKTL 101
>sp|Q9BZX2|UCK2_HUMAN Uridine-cytidine kinase 2 (UCK 2) (Uridine monophosphokinase 2) (Cytidine monophosphokinase 2) Length = 261 Score = 72.8 bits (177), Expect = 2e-13 Identities = 36/80 (45%), Positives = 55/80 (68%), Gaps = 7/80 (8%) Frame = +1 Query: 148 EPFVIGICGGSASGKTTVANTIIENLNIPWVS-------LVCMDSFYKVLSADEKLEASK 306 EPF+IG+ GG+ASGK++V I++ L V ++ DSFY+VL++++K +A K Sbjct: 19 EPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALK 78 Query: 307 SNYNFDHPSAFDIDLIVQTL 366 +NFDHP AFD +LI++TL Sbjct: 79 GQFNFDHPDAFDNELILKTL 98
>sp|Q99PM9|UCK2_MOUSE Uridine-cytidine kinase 2 (UCK 2) (Uridine monophosphokinase 2) (Cytidine monophosphokinase 2) Length = 261 Score = 72.4 bits (176), Expect = 3e-13 Identities = 36/80 (45%), Positives = 55/80 (68%), Gaps = 7/80 (8%) Frame = +1 Query: 148 EPFVIGICGGSASGKTTVANTIIENL-------NIPWVSLVCMDSFYKVLSADEKLEASK 306 EPF+IG+ GG+ASGK++V I++ L + V ++ DSFY+VL++++K +A K Sbjct: 19 EPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYHQKQVVILSQDSFYRVLTSEQKAKALK 78 Query: 307 SNYNFDHPSAFDIDLIVQTL 366 +NFDHP AFD +LI +TL Sbjct: 79 GQFNFDHPDAFDNELIFKTL 98
>sp|Q9VC99|UCK_DROME Probable uridine-cytidine kinase (UCK) (Uridine monophosphokinase) (Cytidine monophosphokinase) Length = 260 Score = 70.9 bits (172), Expect = 9e-13 Identities = 37/86 (43%), Positives = 53/86 (61%), Gaps = 7/86 (8%) Frame = +1 Query: 130 ADGQLKEPFVIGICGGSASGKTTVANTIIENLNIP-------WVSLVCMDSFYKVLSADE 288 A+ ++K PF+IG+ GG+ASGK+TV I+E L V + DSFY+ L+ E Sbjct: 20 ANDEVKSPFLIGVAGGTASGKSTVCKKIMEQLGQAEMDHTQRQVVSISQDSFYRELTPAE 79 Query: 289 KLEASKSNYNFDHPSAFDIDLIVQTL 366 K +A K +NFDHP AF+ +L+ TL Sbjct: 80 KAKAQKGLFNFDHPDAFNEELMYSTL 105
>sp|Q17413|UCK_CAEEL Probable uridine-cytidine kinase (UCK) (Uridine monophosphokinase) (Cytidine monophosphokinase) Length = 248 Score = 68.6 bits (166), Expect = 4e-12 Identities = 37/84 (44%), Positives = 52/84 (61%), Gaps = 9/84 (10%) Frame = +1 Query: 142 LKEPFVIGICGGSASGKTTVANTIIENLN---------IPWVSLVCMDSFYKVLSADEKL 294 LK P +IG+ GG++ GK+T+ IIENLN I V L + SFY+ LSA+EK+ Sbjct: 5 LKLPLLIGVAGGTSCGKSTIVERIIENLNANAKQSGRQIDIVHL-SLHSFYRELSAEEKI 63 Query: 295 EASKSNYNFDHPSAFDIDLIVQTL 366 A + +NFDHP + DL+ +TL Sbjct: 64 LAREGKFNFDHPDQINFDLLAETL 87
>sp|Q6G8V8|URK_STAAS Uridine kinase (Uridine monophosphokinase) (Cytidine monophosphokinase) sp|Q6GG92|URK_STAAR Uridine kinase (Uridine monophosphokinase) (Cytidine monophosphokinase) sp|Q5HFF1|URK_STAAC Uridine kinase (Uridine monophosphokinase) (Cytidine monophosphokinase) sp|P67412|URK_STAAW Uridine kinase (Uridine monophosphokinase) (Cytidine monophosphokinase) sp|P67411|URK_STAAN Uridine kinase (Uridine monophosphokinase) (Cytidine monophosphokinase) sp|P67410|URK_STAAM Uridine kinase (Uridine monophosphokinase) (Cytidine monophosphokinase) Length = 207 Score = 66.2 bits (160), Expect = 2e-11 Identities = 37/78 (47%), Positives = 50/78 (64%), Gaps = 3/78 (3%) Frame = +1 Query: 142 LKEPFVIGICGGSASGKTTVANTIIENLNIPWVSLVCMDSFY---KVLSADEKLEASKSN 312 +K +IGI GGS SGKTTV N I++NL V+L+ D +Y K L+ DE+LE Sbjct: 1 MKATTIIGIAGGSGSGKTTVTNEIMKNLEGHSVALLAQDYYYKDQKHLTFDERLET---- 56 Query: 313 YNFDHPSAFDIDLIVQTL 366 N+DHP AFD DL+++ L Sbjct: 57 -NYDHPFAFDNDLLIENL 73
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 38,869,924 Number of Sequences: 369166 Number of extensions: 695197 Number of successful extensions: 2931 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2839 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2881 length of database: 68,354,980 effective HSP length: 91 effective length of database: 51,544,095 effective search space used: 1700955135 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)