Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_K10
(374 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9NWZ5|UCKL1_HUMAN Uridine/cytidine kinase-like 1 129 2e-30
sp|Q91YL3|UCKL1_MOUSE Uridine/cytidine kinase-like 1 128 4e-30
sp|P27515|URK1_YEAST Uridine kinase (Uridine monophosphokin... 79 2e-15
sp|Q9HA47|UCK1_HUMAN Uridine-cytidine kinase 1 (UCK 1) (Uri... 76 2e-14
sp|P52623|UCK1_MOUSE Uridine-cytidine kinase 1 (UCK 1) (Uri... 76 3e-14
sp|Q9BZX2|UCK2_HUMAN Uridine-cytidine kinase 2 (UCK 2) (Uri... 73 2e-13
sp|Q99PM9|UCK2_MOUSE Uridine-cytidine kinase 2 (UCK 2) (Uri... 72 3e-13
sp|Q9VC99|UCK_DROME Probable uridine-cytidine kinase (UCK) ... 71 9e-13
sp|Q17413|UCK_CAEEL Probable uridine-cytidine kinase (UCK) ... 69 4e-12
sp|Q6G8V8|URK_STAAS Uridine kinase (Uridine monophosphokina... 66 2e-11
>sp|Q9NWZ5|UCKL1_HUMAN Uridine/cytidine kinase-like 1
Length = 548
Score = 129 bits (324), Expect = 2e-30
Identities = 62/94 (65%), Positives = 74/94 (78%), Gaps = 1/94 (1%)
Frame = +1
Query: 88 KRTIYTAGRPPWYTADG-QLKEPFVIGICGGSASGKTTVANTIIENLNIPWVSLVCMDSF 264
KRTIYTAGRPPWY G Q KE F IG+ GGSASGKTTVA IIE L++PWV L+ MDSF
Sbjct: 76 KRTIYTAGRPPWYNEHGTQSKEAFAIGLGGGSASGKTTVARMIIEALDVPWVVLLSMDSF 135
Query: 265 YKVLSADEKLEASKSNYNFDHPSAFDIDLIVQTL 366
YKVL+ ++ +A+ +N+NFDHP AFD DLI+ TL
Sbjct: 136 YKVLTEQQQEQAAHNNFNFDHPDAFDFDLIISTL 169
>sp|Q91YL3|UCKL1_MOUSE Uridine/cytidine kinase-like 1
Length = 548
Score = 128 bits (322), Expect = 4e-30
Identities = 62/94 (65%), Positives = 74/94 (78%), Gaps = 1/94 (1%)
Frame = +1
Query: 88 KRTIYTAGRPPWYTADG-QLKEPFVIGICGGSASGKTTVANTIIENLNIPWVSLVCMDSF 264
KRTIYTAGRPPWY G Q KE F IG+ GGSASGKTTVA IIE L++PWV L+ MDSF
Sbjct: 76 KRTIYTAGRPPWYNEHGTQSKEAFAIGLGGGSASGKTTVARMIIEALDVPWVVLLSMDSF 135
Query: 265 YKVLSADEKLEASKSNYNFDHPSAFDIDLIVQTL 366
YKVL+ ++ +A+ +N+NFDHP AFD DLI+ TL
Sbjct: 136 YKVLTQQQQEQAACNNFNFDHPDAFDFDLIISTL 169
>sp|P27515|URK1_YEAST Uridine kinase (Uridine monophosphokinase)
Length = 501
Score = 79.3 bits (194), Expect = 2e-15
Identities = 34/85 (40%), Positives = 55/85 (64%)
Frame = +1
Query: 115 PPWYTADGQLKEPFVIGICGGSASGKTTVANTIIENLNIPWVSLVCMDSFYKVLSADEKL 294
PPW T P++IGI G S SGKT+VA I+ ++N+PW L+ +D+FY L +++
Sbjct: 51 PPWTT-------PYIIGIGGASGSGKTSVAAKIVSSINVPWTVLISLDNFYNPLGPEDRA 103
Query: 295 EASKSNYNFDHPSAFDIDLIVQTLI 369
A K+ Y+FD P+A ++DL + ++
Sbjct: 104 RAFKNEYDFDEPNAINLDLAYKCIL 128
>sp|Q9HA47|UCK1_HUMAN Uridine-cytidine kinase 1 (UCK 1) (Uridine monophosphokinase 1)
(Cytidine monophosphokinase 1)
Length = 277
Score = 76.3 bits (186), Expect = 2e-14
Identities = 41/86 (47%), Positives = 55/86 (63%), Gaps = 7/86 (8%)
Frame = +1
Query: 130 ADGQLKEPFVIGICGGSASGKTTVANTIIENLNIPWVS-------LVCMDSFYKVLSADE 288
AD + PF+IG+ GG+ASGK+TV I+E L V ++ D FYKVL+A++
Sbjct: 16 ADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQ 75
Query: 289 KLEASKSNYNFDHPSAFDIDLIVQTL 366
K +A K YNFDHP AFD DL+ +TL
Sbjct: 76 KAKALKGQYNFDHPDAFDNDLMHRTL 101
>sp|P52623|UCK1_MOUSE Uridine-cytidine kinase 1 (UCK 1) (Uridine monophosphokinase 1)
(Cytidine monophosphokinase 1)
Length = 277
Score = 75.9 bits (185), Expect = 3e-14
Identities = 41/86 (47%), Positives = 54/86 (62%), Gaps = 7/86 (8%)
Frame = +1
Query: 130 ADGQLKEPFVIGICGGSASGKTTVANTIIENLNIPWVS-------LVCMDSFYKVLSADE 288
AD PF+IG+ GG+ASGK+TV I+E L V ++ D FYKVL+A++
Sbjct: 16 ADRPQPRPFLIGVSGGTASGKSTVCEKIMELLGQNEVDRRQRKLVILSQDCFYKVLTAEQ 75
Query: 289 KLEASKSNYNFDHPSAFDIDLIVQTL 366
K +A K YNFDHP AFD DL+ +TL
Sbjct: 76 KAKALKGQYNFDHPDAFDNDLMHKTL 101
>sp|Q9BZX2|UCK2_HUMAN Uridine-cytidine kinase 2 (UCK 2) (Uridine monophosphokinase 2)
(Cytidine monophosphokinase 2)
Length = 261
Score = 72.8 bits (177), Expect = 2e-13
Identities = 36/80 (45%), Positives = 55/80 (68%), Gaps = 7/80 (8%)
Frame = +1
Query: 148 EPFVIGICGGSASGKTTVANTIIENLNIPWVS-------LVCMDSFYKVLSADEKLEASK 306
EPF+IG+ GG+ASGK++V I++ L V ++ DSFY+VL++++K +A K
Sbjct: 19 EPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALK 78
Query: 307 SNYNFDHPSAFDIDLIVQTL 366
+NFDHP AFD +LI++TL
Sbjct: 79 GQFNFDHPDAFDNELILKTL 98
>sp|Q99PM9|UCK2_MOUSE Uridine-cytidine kinase 2 (UCK 2) (Uridine monophosphokinase 2)
(Cytidine monophosphokinase 2)
Length = 261
Score = 72.4 bits (176), Expect = 3e-13
Identities = 36/80 (45%), Positives = 55/80 (68%), Gaps = 7/80 (8%)
Frame = +1
Query: 148 EPFVIGICGGSASGKTTVANTIIENL-------NIPWVSLVCMDSFYKVLSADEKLEASK 306
EPF+IG+ GG+ASGK++V I++ L + V ++ DSFY+VL++++K +A K
Sbjct: 19 EPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYHQKQVVILSQDSFYRVLTSEQKAKALK 78
Query: 307 SNYNFDHPSAFDIDLIVQTL 366
+NFDHP AFD +LI +TL
Sbjct: 79 GQFNFDHPDAFDNELIFKTL 98
>sp|Q9VC99|UCK_DROME Probable uridine-cytidine kinase (UCK) (Uridine monophosphokinase)
(Cytidine monophosphokinase)
Length = 260
Score = 70.9 bits (172), Expect = 9e-13
Identities = 37/86 (43%), Positives = 53/86 (61%), Gaps = 7/86 (8%)
Frame = +1
Query: 130 ADGQLKEPFVIGICGGSASGKTTVANTIIENLNIP-------WVSLVCMDSFYKVLSADE 288
A+ ++K PF+IG+ GG+ASGK+TV I+E L V + DSFY+ L+ E
Sbjct: 20 ANDEVKSPFLIGVAGGTASGKSTVCKKIMEQLGQAEMDHTQRQVVSISQDSFYRELTPAE 79
Query: 289 KLEASKSNYNFDHPSAFDIDLIVQTL 366
K +A K +NFDHP AF+ +L+ TL
Sbjct: 80 KAKAQKGLFNFDHPDAFNEELMYSTL 105
>sp|Q17413|UCK_CAEEL Probable uridine-cytidine kinase (UCK) (Uridine monophosphokinase)
(Cytidine monophosphokinase)
Length = 248
Score = 68.6 bits (166), Expect = 4e-12
Identities = 37/84 (44%), Positives = 52/84 (61%), Gaps = 9/84 (10%)
Frame = +1
Query: 142 LKEPFVIGICGGSASGKTTVANTIIENLN---------IPWVSLVCMDSFYKVLSADEKL 294
LK P +IG+ GG++ GK+T+ IIENLN I V L + SFY+ LSA+EK+
Sbjct: 5 LKLPLLIGVAGGTSCGKSTIVERIIENLNANAKQSGRQIDIVHL-SLHSFYRELSAEEKI 63
Query: 295 EASKSNYNFDHPSAFDIDLIVQTL 366
A + +NFDHP + DL+ +TL
Sbjct: 64 LAREGKFNFDHPDQINFDLLAETL 87
>sp|Q6G8V8|URK_STAAS Uridine kinase (Uridine monophosphokinase) (Cytidine
monophosphokinase)
sp|Q6GG92|URK_STAAR Uridine kinase (Uridine monophosphokinase) (Cytidine
monophosphokinase)
sp|Q5HFF1|URK_STAAC Uridine kinase (Uridine monophosphokinase) (Cytidine
monophosphokinase)
sp|P67412|URK_STAAW Uridine kinase (Uridine monophosphokinase) (Cytidine
monophosphokinase)
sp|P67411|URK_STAAN Uridine kinase (Uridine monophosphokinase) (Cytidine
monophosphokinase)
sp|P67410|URK_STAAM Uridine kinase (Uridine monophosphokinase) (Cytidine
monophosphokinase)
Length = 207
Score = 66.2 bits (160), Expect = 2e-11
Identities = 37/78 (47%), Positives = 50/78 (64%), Gaps = 3/78 (3%)
Frame = +1
Query: 142 LKEPFVIGICGGSASGKTTVANTIIENLNIPWVSLVCMDSFY---KVLSADEKLEASKSN 312
+K +IGI GGS SGKTTV N I++NL V+L+ D +Y K L+ DE+LE
Sbjct: 1 MKATTIIGIAGGSGSGKTTVTNEIMKNLEGHSVALLAQDYYYKDQKHLTFDERLET---- 56
Query: 313 YNFDHPSAFDIDLIVQTL 366
N+DHP AFD DL+++ L
Sbjct: 57 -NYDHPFAFDNDLLIENL 73
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,869,924
Number of Sequences: 369166
Number of extensions: 695197
Number of successful extensions: 2931
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2839
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2881
length of database: 68,354,980
effective HSP length: 91
effective length of database: 51,544,095
effective search space used: 1700955135
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)