Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_J16
(604 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P97576|GRPE1_RAT GrpE protein homolog 1, mitochondrial p... 176 4e-44
sp|Q99LP6|GRPE1_MOUSE GrpE protein homolog 1, mitochondrial... 173 3e-43
sp|Q5RA81|GRPE1_PONPY GrpE protein homolog 1, mitochondrial... 170 2e-42
sp|P48604|GRPE_DROME GrpE protein homolog, mitochondrial pr... 161 1e-39
sp|Q18421|GRPE_CAEEL GrpE protein homolog, mitochondrial pr... 145 6e-35
sp|Q8TAA5|GRPE2_HUMAN GrpE protein homolog 2, mitochondrial... 127 2e-29
sp|Q5R435|GRPE2_PONPY GrpE protein homolog 2, mitochondrial... 127 2e-29
sp|O88396|GRPE2_MOUSE GrpE protein homolog 2, mitochondrial... 119 5e-27
sp|Q6BTP9|GRPE_DEBHA GrpE protein homolog, mitochondrial pr... 119 8e-27
sp|Q6CRQ1|GRPE_KLULA GrpE protein homolog, mitochondrial pr... 115 7e-26
>sp|P97576|GRPE1_RAT GrpE protein homolog 1, mitochondrial precursor (Mt-GrpE#1)
Length = 217
Score = 176 bits (446), Expect = 4e-44
Identities = 98/169 (57%), Positives = 123/169 (72%), Gaps = 1/169 (0%)
Frame = +3
Query: 72 TDLDESLKQLKEENIKLMDVFKDTEDKYKRALAECENVRQRMTRQVEEAKIFGIQKFCKD 251
TD + K L EE +KL + K+T +KYKRALA+ EN+RQR + VEEAK++GIQ FCKD
Sbjct: 51 TDPSSADKTLLEEKVKLEEQLKETMEKYKRALADTENLRQRSQKLVEEAKLYGIQGFCKD 110
Query: 252 LLDVADILTTATQAVKPEELSKNQ-YLKQMYDGLQMTESQILQVFARHGVERIQPQIGEK 428
LL+VADIL ATQ+V EE+S N +LK +Y+GL MTE QI +VF +HG+ R+ P IG K
Sbjct: 111 LLEVADILEKATQSVPKEEVSNNNPHLKSLYEGLVMTEVQIQKVFTKHGLLRLDP-IGAK 169
Query: 429 FDPNFHEAMFQIPIPENKEKCEVQGTVAVCSKVGYKLYHKTLRPATVGV 575
FDP HEA+F P+ E KE GTVA+ SKVGYKL+ +TLRPA VGV
Sbjct: 170 FDPYEHEALFHTPV-EGKE----PGTVALVSKVGYKLHGRTLRPALVGV 213
>sp|Q99LP6|GRPE1_MOUSE GrpE protein homolog 1, mitochondrial precursor (Mt-GrpE#1)
Length = 217
Score = 173 bits (439), Expect = 3e-43
Identities = 97/169 (57%), Positives = 122/169 (72%), Gaps = 1/169 (0%)
Frame = +3
Query: 72 TDLDESLKQLKEENIKLMDVFKDTEDKYKRALAECENVRQRMTRQVEEAKIFGIQKFCKD 251
TD + K L EE KL + ++T +KYKRALA+ EN+RQR + VEEAK++GIQ FCKD
Sbjct: 51 TDPPSADKTLLEEKAKLEEQLRETMEKYKRALADTENLRQRSQKLVEEAKLYGIQGFCKD 110
Query: 252 LLDVADILTTATQAVKPEELSKNQ-YLKQMYDGLQMTESQILQVFARHGVERIQPQIGEK 428
LL+VADIL ATQ+V EE+S N +LK +Y+GL MTE QI +VF +HG+ R+ P IG K
Sbjct: 111 LLEVADILEKATQSVPKEEISNNNPHLKSLYEGLVMTEVQIQKVFTKHGLLRLDP-IGAK 169
Query: 429 FDPNFHEAMFQIPIPENKEKCEVQGTVAVCSKVGYKLYHKTLRPATVGV 575
FDP HEA+F P+ E KE GTVA+ SKVGYKL+ +TLRPA VGV
Sbjct: 170 FDPYEHEALFHTPV-EGKE----PGTVALVSKVGYKLHGRTLRPALVGV 213
>sp|Q5RA81|GRPE1_PONPY GrpE protein homolog 1, mitochondrial precursor (Mt-GrpE#1)
sp|Q9HAV7|GRPE1_HUMAN GrpE protein homolog 1, mitochondrial precursor (Mt-GrpE#1) (HMGE)
Length = 217
Score = 170 bits (431), Expect = 2e-42
Identities = 92/162 (56%), Positives = 118/162 (72%), Gaps = 1/162 (0%)
Frame = +3
Query: 93 KQLKEENIKLMDVFKDTEDKYKRALAECENVRQRMTRQVEEAKIFGIQKFCKDLLDVADI 272
K L EE +KL + K+T +KYKRALA+ EN+RQR + VEEAK++GIQ FCKDLL+VAD+
Sbjct: 58 KTLLEEKVKLEEQLKETVEKYKRALADTENLRQRSQKLVEEAKLYGIQAFCKDLLEVADV 117
Query: 273 LTTATQAVKPEEL-SKNQYLKQMYDGLQMTESQILQVFARHGVERIQPQIGEKFDPNFHE 449
L ATQ V EE+ N +LK +Y+GL MTE QI +VF +HG+ ++ P +G KFDP HE
Sbjct: 118 LEKATQCVPKEEIKDDNPHLKNLYEGLVMTEVQIQKVFTKHGLLKLNP-VGAKFDPYEHE 176
Query: 450 AMFQIPIPENKEKCEVQGTVAVCSKVGYKLYHKTLRPATVGV 575
A+F P+ E KE GTVA+ SKVGYKL+ +TLRPA VGV
Sbjct: 177 ALFHTPV-EGKE----PGTVALVSKVGYKLHGRTLRPALVGV 213
>sp|P48604|GRPE_DROME GrpE protein homolog, mitochondrial precursor (dRoe1)
Length = 213
Score = 161 bits (408), Expect = 1e-39
Identities = 87/180 (48%), Positives = 118/180 (65%)
Frame = +3
Query: 36 SDQPTSNKHVETTDLDESLKQLKEENIKLMDVFKDTEDKYKRALAECENVRQRMTRQVEE 215
++Q + E L + L KE+N +LMD KYKR+LA+ EN+R R+ +Q+ +
Sbjct: 44 TEQKATESSPEVEKLTKELAAAKEQNAELMD-------KYKRSLADSENMRNRLNKQISD 96
Query: 216 AKIFGIQKFCKDLLDVADILTTATQAVKPEELSKNQYLKQMYDGLQMTESQILQVFARHG 395
AKIFGIQ FCKDLL+VAD L ATQAV ++LS N LK +Y+GL MT + +LQVF RHG
Sbjct: 97 AKIFGIQSFCKDLLEVADTLGHATQAVPKDKLSGNADLKNLYEGLTMTRASLLQVFKRHG 156
Query: 396 VERIQPQIGEKFDPNFHEAMFQIPIPENKEKCEVQGTVAVCSKVGYKLYHKTLRPATVGV 575
+E + P I +KFDPN HEA+FQ ++K TV +K+GYKL+ + +RPA VGV
Sbjct: 157 LEPLDP-INQKFDPNQHEALFQ-----KEDKTVEPNTVVEVTKLGYKLHERCIRPALVGV 210
>sp|Q18421|GRPE_CAEEL GrpE protein homolog, mitochondrial precursor
Length = 237
Score = 145 bits (367), Expect = 6e-35
Identities = 73/147 (49%), Positives = 104/147 (70%), Gaps = 1/147 (0%)
Frame = +3
Query: 138 DTEDKYKRALAECENVRQRMTRQVEEAKIFGIQKFCKDLLDVADILTTATQAVKPEEL-S 314
D +DKY+R+LAE ENVR+R +Q ++AK+F IQ FCKDLL+V+DIL A ++VKPE+L S
Sbjct: 92 DFKDKYQRSLAETENVRRRGIKQTDDAKVFAIQSFCKDLLEVSDILDIAVKSVKPEDLES 151
Query: 315 KNQYLKQMYDGLQMTESQILQVFARHGVERIQPQIGEKFDPNFHEAMFQIPIPENKEKCE 494
+ LK +++G+ MT + + + FA+HG+ + P EKFDPN HEA+FQIP K+
Sbjct: 152 GGKALKDLFEGVSMTRTVMAKTFAKHGLVTVDP-TNEKFDPNLHEAVFQIPSANAKQPV- 209
Query: 495 VQGTVAVCSKVGYKLYHKTLRPATVGV 575
G + VC+K+GY L + +RPA VGV
Sbjct: 210 --GHIEVCTKIGYSLKERPIRPAQVGV 234
>sp|Q8TAA5|GRPE2_HUMAN GrpE protein homolog 2, mitochondrial precursor (Mt-GrpE#2)
Length = 225
Score = 127 bits (320), Expect = 2e-29
Identities = 68/163 (41%), Positives = 109/163 (66%), Gaps = 2/163 (1%)
Frame = +3
Query: 93 KQLKEENIKLMDVFKDTEDKYKRALAECENVRQRMTRQVEEAKIFGIQKFCKDLLDVADI 272
+ L+ + +KL +D +Y+RA+A+CEN+R+R R VE+AKIFGIQ FCKDL++VADI
Sbjct: 60 RALRVKAVKLEKEVQDLTVRYQRAIADCENIRRRTQRCVEDAKIFGIQSFCKDLVEVADI 119
Query: 273 LTTATQAVKPEELSKNQ--YLKQMYDGLQMTESQILQVFARHGVERIQPQIGEKFDPNFH 446
L T+ + E ++Q L++++ GL + E+++ VFA+HG+E++ P IG+K+DP+ H
Sbjct: 120 LEKTTECISEESEPEDQKLTLEKVFRGLLLLEAKLKSVFAKHGLEKLTP-IGDKYDPHEH 178
Query: 447 EAMFQIPIPENKEKCEVQGTVAVCSKVGYKLYHKTLRPATVGV 575
E + +P + GTVA+ + GYKL+ +T+R A V V
Sbjct: 179 ELICHVPAGVGVQ----PGTVALVRQDGYKLHGRTIRLARVEV 217
>sp|Q5R435|GRPE2_PONPY GrpE protein homolog 2, mitochondrial precursor (Mt-GrpE#2)
Length = 225
Score = 127 bits (319), Expect = 2e-29
Identities = 68/163 (41%), Positives = 109/163 (66%), Gaps = 2/163 (1%)
Frame = +3
Query: 93 KQLKEENIKLMDVFKDTEDKYKRALAECENVRQRMTRQVEEAKIFGIQKFCKDLLDVADI 272
+ L+ + +KL +D +Y+RA+A+CEN+R+R R VE+AKIFGIQ FCKDL++VADI
Sbjct: 60 RALRVKAVKLEKEVQDLTVRYQRAVADCENIRRRTQRCVEDAKIFGIQSFCKDLVEVADI 119
Query: 273 LTTATQAVKPEELSKNQ--YLKQMYDGLQMTESQILQVFARHGVERIQPQIGEKFDPNFH 446
L T+ + E ++Q L++++ GL + E+++ VFA+HG+E++ P IG+K+DP+ H
Sbjct: 120 LEKTTECISEESEPEDQKLTLEKVFRGLLLLEAKLKSVFAKHGLEKLTP-IGDKYDPHEH 178
Query: 447 EAMFQIPIPENKEKCEVQGTVAVCSKVGYKLYHKTLRPATVGV 575
E + +P + GTVA+ + GYKL+ +T+R A V V
Sbjct: 179 ELICHVPAGVGVQ----PGTVALVRQDGYKLHGRTIRLARVEV 217
>sp|O88396|GRPE2_MOUSE GrpE protein homolog 2, mitochondrial precursor (Mt-GrpE#2)
Length = 224
Score = 119 bits (299), Expect = 5e-27
Identities = 66/163 (40%), Positives = 107/163 (65%), Gaps = 4/163 (2%)
Frame = +3
Query: 99 LKEENIKLMDVFKDTEDKYKRALAECENVRQRMTRQVEEAKIFGIQKFCKDLLDVADIL- 275
L+ + +KL +D +Y+RA+A+CEN+R+R R VE+AKIFGIQ FCKDL++VADIL
Sbjct: 61 LRLKAVKLEKEVQDLTLRYQRAVADCENIRRRTQRCVEDAKIFGIQSFCKDLVEVADILE 120
Query: 276 ---TTATQAVKPEELSKNQYLKQMYDGLQMTESQILQVFARHGVERIQPQIGEKFDPNFH 446
++ +PE+ + L++++ GL + E+++ VF +HG+E++ P IG+K+DP+ H
Sbjct: 121 KTAKCCSEGAEPED--HRRTLEKVFQGLSLLEARLKSVFTKHGLEKMTP-IGDKYDPHEH 177
Query: 447 EAMFQIPIPENKEKCEVQGTVAVCSKVGYKLYHKTLRPATVGV 575
E + +P + GTVA+ + GYKL+ +T+R A V V
Sbjct: 178 ELICHMPAGVGVQ----PGTVALVRQDGYKLHGRTIRLAQVEV 216
>sp|Q6BTP9|GRPE_DEBHA GrpE protein homolog, mitochondrial precursor
Length = 243
Score = 119 bits (297), Expect = 8e-27
Identities = 66/171 (38%), Positives = 103/171 (60%)
Frame = +3
Query: 63 VETTDLDESLKQLKEENIKLMDVFKDTEDKYKRALAECENVRQRMTRQVEEAKIFGIQKF 242
VE +++DE +L +++ +L D+ ++ Y RA+A+ N+++ + ++A+ F +QKF
Sbjct: 77 VEVSEIDELKAKLTKKDRELADM----KNHYARAIADFRNLQESTKLEKQKARDFALQKF 132
Query: 243 CKDLLDVADILTTATQAVKPEELSKNQYLKQMYDGLQMTESQILQVFARHGVERIQPQIG 422
KDLL+ D A AVK + L N +K +YDG+ MT + + ARHG+E++ P IG
Sbjct: 133 AKDLLESVDNFDLALNAVKEDTLKNNSEVKNLYDGVDMTRNVFEKTLARHGIEKVDP-IG 191
Query: 423 EKFDPNFHEAMFQIPIPENKEKCEVQGTVAVCSKVGYKLYHKTLRPATVGV 575
E+FDPN HEA F+I P+ + GTV + GY L + LRPA VGV
Sbjct: 192 EQFDPNQHEATFEIAQPDKE-----PGTVFHVQQNGYTLNSRVLRPAKVGV 237
>sp|Q6CRQ1|GRPE_KLULA GrpE protein homolog, mitochondrial precursor
Length = 243
Score = 115 bits (289), Expect = 7e-26
Identities = 63/173 (36%), Positives = 101/173 (58%), Gaps = 3/173 (1%)
Frame = +3
Query: 66 ETTDLDESLKQLKEENIKLMDVFKDT---EDKYKRALAECENVRQRMTRQVEEAKIFGIQ 236
E +L E K++K+ KL K+ +D+ R++A+ N+++ + +++AK F +Q
Sbjct: 71 EDANLTEEQKKIKDLETKLDAKTKEASEFKDRLLRSVADFRNLQEVTKKDIQKAKDFALQ 130
Query: 237 KFCKDLLDVADILTTATQAVKPEELSKNQYLKQMYDGLQMTESQILQVFARHGVERIQPQ 416
KF KDLL+ D A A KPE L ++Q L +Y G++MT + +HG+E++ P
Sbjct: 131 KFAKDLLESVDNFGHALNAFKPETLEQSQELSDLYTGVKMTRDVFEKTLKKHGIEQLNP- 189
Query: 417 IGEKFDPNFHEAMFQIPIPENKEKCEVQGTVAVCSKVGYKLYHKTLRPATVGV 575
IGE FDPN HEA F++P P+ + GTV ++GY L + +RPA VG+
Sbjct: 190 IGESFDPNKHEATFELPQPDKE-----PGTVFHVQQIGYTLNDRVIRPAKVGI 237
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,169,845
Number of Sequences: 369166
Number of extensions: 1254931
Number of successful extensions: 4585
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4227
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4399
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4650991475
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)