Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_J11
(665 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P12955|PEPD_HUMAN Xaa-Pro dipeptidase (X-Pro dipeptidase... 227 2e-59
sp|Q11136|PEPD_MOUSE Xaa-Pro dipeptidase (X-Pro dipeptidase... 224 2e-58
sp|P43590|YFH6_YEAST Hypothetical 61.8 kDa peptidase in MPR... 132 8e-31
sp|P15034|AMPP_ECOLI Xaa-Pro aminopeptidase (X-Pro aminopep... 106 6e-23
sp|P0A3Z2|AMPP1_STRLI Xaa-Pro aminopeptidase I (X-Pro amino... 93 5e-19
sp|P44881|AMPP_HAEIN Xaa-Pro aminopeptidase (X-Pro aminopep... 92 2e-18
sp|P21165|PEPQ_ECOLI Xaa-Pro dipeptidase (X-Pro dipeptidase... 86 7e-17
sp|P0A3Z4|AMPP2_STRLI Xaa-Pro aminopeptidase II (X-Pro amin... 85 1e-16
sp|Q10439|YDE5_SCHPO Probable peptidase C12B10.05 56 1e-07
sp|P76524|YPDF_ECOLI Aminopeptidase ypdF 56 1e-07
>sp|P12955|PEPD_HUMAN Xaa-Pro dipeptidase (X-Pro dipeptidase) (Proline dipeptidase)
(Prolidase) (Imidodipeptidase)
Length = 493
Score = 227 bits (579), Expect = 2e-59
Identities = 120/195 (61%), Positives = 138/195 (70%)
Frame = +2
Query: 2 CSFPVNGHFTKDQKIVYEAVLAASRAVKNACKPGVRWTDMHLLA*RIILSSLKEAGLLQG 181
CSFP NG FT DQK VYEAVL +SRAV A KPGV W DMH LA RI L L G+L G
Sbjct: 290 CSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSG 349
Query: 182 DVNEMMAVRLGAVFMPHGLGHLLGVDVHDVGGYIEDAIPRSELSGLRSLRTTQLLQENME 361
V+ M+ LGAVFMPHGLGH LG+DVHDVGGY E + R + GLRSLRT + LQ M
Sbjct: 350 SVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPE-GVERIDEPGLRSLRTARHLQPGMV 408
Query: 362 LTVEPGCYFIDILLDAAINNPEQARFMVINEINRFTRFGGVRIEDDIIVTSTGIECMTEV 541
LTVEPG YFID LLD A+ +P +A F+ + RF FGGVRIE+D++VT +GIE +T V
Sbjct: 409 LTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCV 468
Query: 542 PRTCEEIEQRMAGND 586
PRT EEIE MAG D
Sbjct: 469 PRTVEEIEACMAGCD 483
>sp|Q11136|PEPD_MOUSE Xaa-Pro dipeptidase (X-Pro dipeptidase) (Proline dipeptidase)
(Prolidase) (Imidodipeptidase) (Peptidase 4)
Length = 493
Score = 224 bits (570), Expect = 2e-58
Identities = 118/198 (59%), Positives = 138/198 (69%)
Frame = +2
Query: 2 CSFPVNGHFTKDQKIVYEAVLAASRAVKNACKPGVRWTDMHLLA*RIILSSLKEAGLLQG 181
CSFP NG FT+DQK +YEAVL + R V + KPGV W DMH LA RI L L GLL G
Sbjct: 290 CSFPANGKFTEDQKAIYEAVLRSCRTVMSTMKPGVWWPDMHRLADRIHLEELARIGLLSG 349
Query: 182 DVNEMMAVRLGAVFMPHGLGHLLGVDVHDVGGYIEDAIPRSELSGLRSLRTTQLLQENME 361
V+ M+ V LGAVFMPHGLGH LG+DVHDVGGY E + R + GLRSLRT + L+ M
Sbjct: 350 SVDAMLQVHLGAVFMPHGLGHFLGLDVHDVGGYPE-GVERIDEPGLRSLRTARHLEPGMV 408
Query: 362 LTVEPGCYFIDILLDAAINNPEQARFMVINEINRFTRFGGVRIEDDIIVTSTGIECMTEV 541
LTVEPG YFID LLD A+ +P QA F + RF FGGVRIE+D++VT +G+E +T V
Sbjct: 409 LTVEPGIYFIDHLLDQALADPAQACFFNQEVLQRFRNFGGVRIEEDVVVTDSGMELLTCV 468
Query: 542 PRTCEEIEQRMAGNDYMS 595
PRT EEIE MAG D S
Sbjct: 469 PRTVEEIEACMAGCDKAS 486
>sp|P43590|YFH6_YEAST Hypothetical 61.8 kDa peptidase in MPR1-GCN20 intergenic region
Length = 535
Score = 132 bits (332), Expect = 8e-31
Identities = 73/192 (38%), Positives = 107/192 (55%), Gaps = 5/192 (2%)
Frame = +2
Query: 8 FPVNGHFTKDQKIVYEAVLAASRAVKNACKPGVRWTDMHLLA*RIILSSLKEAGLLQGDV 187
FP +G FT + + VYE VL KPG +W D+H L ++++ G+ + +
Sbjct: 332 FPTSGKFTAEHREVYETVLDMQNQAMERIKPGAKWDDLHALTHKVLIKHFLSMGIFKKEF 391
Query: 188 --NEMMAVRLGAVFMPHGLGHLLGVDVHDVGG--YIEDAIPRSELSGLRSLRTTQLLQEN 355
+E+ R F PHGLGH+LG+DVHDVGG +D P R LR + L+EN
Sbjct: 392 SEDEIFKRRASCAFYPHGLGHMLGLDVHDVGGNPNYDDPDPM-----FRYLRIRRPLKEN 446
Query: 356 MELTVEPGCYFIDILLDAAI-NNPEQARFMVINEINRFTRFGGVRIEDDIIVTSTGIECM 532
M +T EPGCYF L+ + +PE+ + ++ + R+ GGVRIEDDI+VT G E +
Sbjct: 447 MVITNEPGCYFNQFLIKEFLEKHPERLEVVDMSVLKRYMYVGGVRIEDDILVTKDGYENL 506
Query: 533 TEVPRTCEEIEQ 568
T + +EIE+
Sbjct: 507 TGITSDPDEIEK 518
>sp|P15034|AMPP_ECOLI Xaa-Pro aminopeptidase (X-Pro aminopeptidase) (Aminopeptidase P II)
(APP-II) (Aminoacylproline aminopeptidase)
Length = 441
Score = 106 bits (264), Expect = 6e-23
Identities = 73/191 (38%), Positives = 103/191 (53%), Gaps = 1/191 (0%)
Frame = +2
Query: 5 SFPVNGHFTKDQKIVYEAVLAASRAVKNACKPGVRWTDMHLLA*RIILSSLKEAGLLQGD 184
+FPVNG FT+ Q+ +Y+ VL + +PG ++ RI++S L + G+L+GD
Sbjct: 276 TFPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSILEVTGEVVRIMVSGLVKLGILKGD 335
Query: 185 VNEMMAVRLGAVFMPHGLGHLLGVDVHDVGGYIEDAIPRSELSGLRSLRTTQLLQENMEL 364
V+E++A F HGL H LG+DVHDVG Y +D +++L+ M L
Sbjct: 336 VDELIAQNAHRPFFMHGLSHWLGLDVHDVGVYGQD--------------RSRILEPGMVL 381
Query: 365 TVEPGCYFIDILLDAAINNPEQARFMVINEINRFTRFGGVRIEDDIIVTSTGIECMT-EV 541
TVEPG Y I DA + PEQ R + G+RIEDDI++T TG E +T V
Sbjct: 382 TVEPGLY---IAPDAEV--PEQYRGI------------GIRIEDDIVITETGNENLTASV 424
Query: 542 PRTCEEIEQRM 574
+ EEIE M
Sbjct: 425 VKKPEEIEALM 435
>sp|P0A3Z2|AMPP1_STRLI Xaa-Pro aminopeptidase I (X-Pro aminopeptidase I) (Aminopeptidase P
I) (APP) (PEPP I) (Aminoacylproline aminopeptidase I)
sp|P0A3Z1|AMPP1_STRCO Xaa-Pro aminopeptidase I (X-Pro aminopeptidase I) (Aminopeptidase P
I) (APP) (PEPP I) (Aminoacylproline aminopeptidase I)
Length = 491
Score = 93.2 bits (230), Expect = 5e-19
Identities = 66/192 (34%), Positives = 100/192 (52%), Gaps = 1/192 (0%)
Frame = +2
Query: 5 SFPVNGHFTKDQKIVYEAVLAASRAVKNACKPGVRWTDMHLLA*RIILSSLKEAGLLQGD 184
+ P++G +++ QK +Y+AV A A A +PG ++ D H + R++ L E GL++G
Sbjct: 324 TLPISGTYSELQKKIYDAVYDAQEAGIAAVRPGAKYRDFHDASQRVLAERLVEWGLVEGP 383
Query: 185 VNEMMAVRLGAVFMPHGLGHLLGVDVHDVGGYIEDAIPRSELSGLRSLRTTQLLQENMEL 364
V ++ + L + HG GH+LG+DVHD A S + G L+ M L
Sbjct: 384 VERVLELGLQRRWTLHGTGHMLGMDVHDCAA----ARVESYVDG--------TLEPGMVL 431
Query: 365 TVEPGCYFIDILLDAAINNPEQARFMVINEINRFTRFGGVRIEDDIIVTSTGIECMTE-V 541
TVEPG YF QA + + E R GVRIEDDI+VT+ G ++ +
Sbjct: 432 TVEPGLYF-------------QADDLTVPEEYRGI---GVRIEDDILVTADGNRNLSAGL 475
Query: 542 PRTCEEIEQRMA 577
PR +E+E+ MA
Sbjct: 476 PRRSDEVEEWMA 487
>sp|P44881|AMPP_HAEIN Xaa-Pro aminopeptidase (X-Pro aminopeptidase) (Aminopeptidase P II)
(APP-II) (Aminoacylproline aminopeptidase)
Length = 430
Score = 91.7 bits (226), Expect = 2e-18
Identities = 65/191 (34%), Positives = 97/191 (50%), Gaps = 1/191 (0%)
Frame = +2
Query: 5 SFPVNGHFTKDQKIVYEAVLAASRAVKNACKPGVRWTDMHLLA*RIILSSLKEAGLLQGD 184
+FPVNG F++ Q+ +YE VL A + PG + RI L + G+L+GD
Sbjct: 269 TFPVNGKFSQPQREIYELVLKAQKRAIELLVPGNSIKQANDEVIRIKTQGLVDLGILKGD 328
Query: 185 VNEMMAVRLGAVFMPHGLGHLLGVDVHDVGGYIEDAIPRSELSGLRSLRTTQLLQENMEL 364
V+ ++ + F HGLGH LG+DVHDVG Y +D ++L+ M +
Sbjct: 329 VDTLIEQQAYRQFYMHGLGHWLGLDVHDVGSYGQD--------------KQRILEIGMVI 374
Query: 365 TVEPGCYFIDILLDAAINNPEQARFMVINEINRFTRFGGVRIEDDIIVTSTGIECMT-EV 541
TVEPG Y + DA + PEQ + + GVRIED++++T G + +T V
Sbjct: 375 TVEPGIYISE---DADV--PEQYKGI------------GVRIEDNLLMTEYGNKILTAAV 417
Query: 542 PRTCEEIEQRM 574
P+ +IE M
Sbjct: 418 PKEIADIENLM 428
>sp|P21165|PEPQ_ECOLI Xaa-Pro dipeptidase (X-Pro dipeptidase) (Proline dipeptidase)
(Prolidase) (Imidodipeptidase)
Length = 443
Score = 86.3 bits (212), Expect = 7e-17
Identities = 53/150 (35%), Positives = 81/150 (54%), Gaps = 3/150 (2%)
Frame = +2
Query: 95 KPGVRWTDMHLLA*RIILSSLKEAGLLQGDVNEMMAVR-LGAVFMPHGLGHLLGVDVHDV 271
K GV + D H+ + I L++ ++ E M L FMPHG+GH LG+ VHDV
Sbjct: 289 KAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDV 348
Query: 272 GGYIED--AIPRSELSGLRSLRTTQLLQENMELTVEPGCYFIDILLDAAINNPEQARFMV 445
G+++D + + LR T++LQ M LT+EPG YFI+ LL A + ++
Sbjct: 349 AGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIESLL-APWREGQFSKHFN 407
Query: 446 INEINRFTRFGGVRIEDDIIVTSTGIECMT 535
+I FGG+RIED++++ +E MT
Sbjct: 408 WQKIEALKPFGGIRIEDNVVIHENNVENMT 437
>sp|P0A3Z4|AMPP2_STRLI Xaa-Pro aminopeptidase II (X-Pro aminopeptidase II) (Aminopeptidase
P II) (APP) (PEPP II) (Aminoacylproline aminopeptidase
II)
sp|P0A3Z3|AMPP2_STRCO Xaa-Pro aminopeptidase II (X-Pro aminopeptidase II) (Aminopeptidase
P II) (APP) (PEPP II) (Aminoacylproline aminopeptidase
II)
Length = 470
Score = 85.1 bits (209), Expect = 1e-16
Identities = 67/192 (34%), Positives = 93/192 (48%), Gaps = 1/192 (0%)
Frame = +2
Query: 5 SFPVNGHFTKDQKIVYEAVLAASRAVKNACKPGVRWTDMHLLA*RIILSSLKEAGLLQGD 184
+ P++G FT Q+ VY+AV A A KPG + D H A R + + L E G ++G
Sbjct: 303 TLPISGTFTPLQREVYDAVYEAQEAGIATVKPGAAYRDFHEAAQRHLAARLVEWGFIEGP 362
Query: 185 VNEMMAVRLGAVFMPHGLGHLLGVDVHDVGGYIEDAIPRSELSGLRSLRTTQLLQENMEL 364
+ L F G GH+LG+DVHD A R+E +L+ M L
Sbjct: 363 AERAYELGLQRRFTMAGTGHMLGLDVHDC------ARARTE------EYVEGVLEPGMCL 410
Query: 365 TVEPGCYFIDILLDAAINNPEQARFMVINEINRFTRFGGVRIEDDIIVTSTGIECMTE-V 541
TVEPG YF QA + + E R GVRIEDD++VT G E ++ +
Sbjct: 411 TVEPGLYF-------------QADDLTVPEEWRGI---GVRIEDDLVVTEDGHENLSAGL 454
Query: 542 PRTCEEIEQRMA 577
PR+ +E+E MA
Sbjct: 455 PRSADEVEAWMA 466
>sp|Q10439|YDE5_SCHPO Probable peptidase C12B10.05
Length = 486
Score = 55.8 bits (133), Expect = 1e-07
Identities = 49/190 (25%), Positives = 86/190 (45%), Gaps = 3/190 (1%)
Frame = +2
Query: 5 SFPVNGHFTKDQKIVYEAVLAASRAVKNACKPGVRWT--DMHLLA*RIILSSLKEAGLLQ 178
++P+NG F+ Q+ +Y+AVL + C W+ D+H + +++ LK+ G+
Sbjct: 332 TWPINGKFSTVQRDLYQAVLNVQKKCIKYCCTSNGWSLADIHFESVKLMHEELKQVGI-H 390
Query: 179 GDVNEMMAVRLGAVFMPHGLGHLLGVDVHDVGGYIEDAIPRSELSGLRSLRTTQLLQENM 358
G E+ + PH +GH +G+++HD S +G + LR +N
Sbjct: 391 GTKREITDI-----LYPHSIGHEIGLEIHDC----------STNNGYQPLR------KNQ 429
Query: 359 ELTVEPGCYFIDILLDAAINNPEQARFMVINEINRFTRFGGVRIEDDIIVTSTGIECMTE 538
+T+EPG Y PE+ + ++ + +RIED +IV +T
Sbjct: 430 VITIEPGLYV-----------PEEDGW------PQWAQGIAIRIEDSVIVGDDKPFVLTS 472
Query: 539 -VPRTCEEIE 565
P+ EEIE
Sbjct: 473 AAPKEIEEIE 482
>sp|P76524|YPDF_ECOLI Aminopeptidase ypdF
Length = 361
Score = 55.8 bits (133), Expect = 1e-07
Identities = 57/168 (33%), Positives = 71/168 (42%)
Frame = +2
Query: 47 VYEAVLAASRAVKNACKPGVRWTDMHLLA*RIILSSLKEAGLLQGDVNEMMAVRLGAVFM 226
VY+ VL A A +A +PGVR + A R+I EAG GD +
Sbjct: 245 VYQIVLQAQLAAISAIRPGVRCQQVDDAARRVIT----EAGY--GD------------YF 286
Query: 227 PHGLGHLLGVDVHDVGGYIEDAIPRSELSGLRSLRTTQLLQENMELTVEPGCYFIDILLD 406
H GH +G++VH ED PR S R T LQ M LTVEPG Y
Sbjct: 287 GHNTGHAIGIEVH------ED--PRF------SPRDTTTLQPGMLLTVEPGIYL------ 326
Query: 407 AAINNPEQARFMVINEINRFTRFGGVRIEDDIIVTSTGIECMTEVPRT 550
P Q GGVRIED ++VT G E + +P+T
Sbjct: 327 -----PGQ---------------GGVRIEDVVLVTPQGAEVLYAMPKT 354
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,454,002
Number of Sequences: 369166
Number of extensions: 1439562
Number of successful extensions: 3707
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3554
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3663
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5608903050
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)