Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_J05
(649 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8BH16|FBXL2_MOUSE F-box/LRR-repeat protein 2 (F-box and... 55 1e-07
sp|Q9UKC9|FBXL2_HUMAN F-box/LRR-repeat protein 2 (F-box and... 55 2e-07
sp|P34284|YKK7_CAEEL Hypothetical F-box/LRR-repeat protein ... 54 3e-07
sp|Q9UJT9|FBXL7_HUMAN F-box/LRR-repeat protein 7 (F-box and... 53 8e-07
sp|Q96IG2|FXL20_HUMAN F-box/LRR-repeat protein 20 (F-box an... 52 1e-06
sp|Q9QZH7|FXL20_RAT F-box/LRR-repeat protein 20 (F-box and ... 50 4e-06
sp|Q9CZV8|FXL20_MOUSE F-box/LRR-repeat protein 20 (F-box an... 50 4e-06
sp|Q8WV35|LRC29_HUMAN Leucine-rich repeat-containing protei... 47 6e-05
sp|Q8NEE6|FXL13_HUMAN F-box/LRR-repeat protein 13 (F-box an... 46 7e-05
sp|Q8CDU4|FXL13_MOUSE F-box/LRR-repeat protein 13 (F-box an... 45 2e-04
>sp|Q8BH16|FBXL2_MOUSE F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein
2)
Length = 423
Score = 55.5 bits (132), Expect = 1e-07
Identities = 39/132 (29%), Positives = 66/132 (50%)
Frame = +1
Query: 103 NLKFLSIHKATELSKLALLDLFNKPDSQLTKLISLDLNECSVIDDEILNSILELCGKNLR 282
N++ L+++ T+++ L +KL LDL C + + L I E C +NL
Sbjct: 105 NIEHLNLNGCTKITDSTCYSL----SRFCSKLKHLDLTSCVSVTNSSLKGISEGC-RNLE 159
Query: 283 ILSLNWCWNITDDGLNNLVLVAINMERLSLIGNHIIKGTAFQNLVGRWLHLRLLNLTNCN 462
L+L+WC IT +G+ LV ++ L L G ++ A +++ L LNL +C+
Sbjct: 160 YLNLSWCDQITKEGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNHCHELVSLNLQSCS 219
Query: 463 QIDDDLLKTIAR 498
+I DD + I R
Sbjct: 220 RITDDGVVQICR 231
Score = 51.2 bits (121), Expect = 2e-06
Identities = 51/176 (28%), Positives = 77/176 (43%), Gaps = 4/176 (2%)
Frame = +1
Query: 16 RNCQKLSVLSISYADTFTDNVVLPLRTLSNLKFLSIHKATELSKL--ALLDLFNKPDSQL 189
R C +L L +S TD + L N L + +A S L A L + +L
Sbjct: 231 RGCHRLQALCLSGCSNLTDASLTALGL--NCPRLQVLEAARCSHLTDAGFTLLARNCHEL 288
Query: 190 TKLISLDLNECSVIDDEILNSILELCGKNLRILSLNWCWNITDDGLNNLVLVAINMERLS 369
K+ DL EC +I D L + C K L+ LSL+ C ITD+G+ +L ERL
Sbjct: 289 EKM---DLEECVLITDSTLVQLSIHCPK-LQALSLSHCELITDEGILHLSSSTCGHERLR 344
Query: 370 L--IGNHIIKGTAFQNLVGRWLHLRLLNLTNCNQIDDDLLKTIARQMPETYIFDYF 531
+ + N ++ A + L L L +C Q+ +K + Q+P + YF
Sbjct: 345 VLELDNCLLVTDASLEHLENCRGLERLELYDCQQVTRAGIKRMRAQLPHVKVHAYF 400
Score = 50.8 bits (120), Expect = 3e-06
Identities = 45/164 (27%), Positives = 72/164 (43%), Gaps = 1/164 (0%)
Frame = +1
Query: 22 CQKLSVLSISYADTFT-DNVVLPLRTLSNLKFLSIHKATELSKLALLDLFNKPDSQLTKL 198
C+ L L++S+ D T + + +R LK L + T+L AL + N +L
Sbjct: 155 CRNLEYLNLSWCDQITKEGIEALVRGCRGLKALLLRGCTQLEDEALKHIQN----HCHEL 210
Query: 199 ISLDLNECSVIDDEILNSILELCGKNLRILSLNWCWNITDDGLNNLVLVAINMERLSLIG 378
+SL+L CS I D+ + I C + L+ L L+ C N+TD L L L ++ L
Sbjct: 211 VSLNLQSCSRITDDGVVQICRGCHR-LQALCLSGCSNLTDASLTALGLNCPRLQVLEAAR 269
Query: 379 NHIIKGTAFQNLVGRWLHLRLLNLTNCNQIDDDLLKTIARQMPE 510
+ F L L ++L C I D L ++ P+
Sbjct: 270 CSHLTDAGFTLLARNCHELEKMDLEECVLITDSTLVQLSIHCPK 313
Score = 45.4 bits (106), Expect = 1e-04
Identities = 39/131 (29%), Positives = 55/131 (41%), Gaps = 7/131 (5%)
Frame = +1
Query: 139 LSKLALLDLFNKPDSQLTKLIS-------LDLNECSVIDDEILNSILELCGKNLRILSLN 297
L KL+L DS L L+LN C+ I D S+ C K L+ L L
Sbjct: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSK-LKHLDLT 138
Query: 298 WCWNITDDGLNNLVLVAINMERLSLIGNHIIKGTAFQNLVGRWLHLRLLNLTNCNQIDDD 477
C ++T+ L + N+E L+L I + LV L+ L L C Q++D+
Sbjct: 139 SCVSVTNSSLKGISEGCRNLEYLNLSWCDQITKEGIEALVRGCRGLKALLLRGCTQLEDE 198
Query: 478 LLKTIARQMPE 510
LK I E
Sbjct: 199 ALKHIQNHCHE 209
Score = 42.4 bits (98), Expect = 0.001
Identities = 35/138 (25%), Positives = 63/138 (45%)
Frame = +1
Query: 82 LPLRTLSNLKFLSIHKATELSKLALLDLFNKPDSQLTKLISLDLNECSVIDDEILNSILE 261
L LR S L +++ + ++SK + + + Q L + + ++ ++ +I +
Sbjct: 19 LLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRVDLFNFQTD----VEGRVVENISK 74
Query: 262 LCGKNLRILSLNWCWNITDDGLNNLVLVAINMERLSLIGNHIIKGTAFQNLVGRWLHLRL 441
CG LR LSL C + D L N+E L+L G I + +L L+
Sbjct: 75 RCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKH 134
Query: 442 LNLTNCNQIDDDLLKTIA 495
L+LT+C + + LK I+
Sbjct: 135 LDLTSCVSVTNSSLKGIS 152
>sp|Q9UKC9|FBXL2_HUMAN F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein
2) (F-box protein FBL2/FBL3)
Length = 423
Score = 55.1 bits (131), Expect = 2e-07
Identities = 40/132 (30%), Positives = 66/132 (50%)
Frame = +1
Query: 103 NLKFLSIHKATELSKLALLDLFNKPDSQLTKLISLDLNECSVIDDEILNSILELCGKNLR 282
N++ L+++ T+++ L +KL LDL C I + L I E C +NL
Sbjct: 105 NIEHLNLNGCTKITDSTCYSL----SRFCSKLKHLDLTSCVSITNSSLKGISEGC-RNLE 159
Query: 283 ILSLNWCWNITDDGLNNLVLVAINMERLSLIGNHIIKGTAFQNLVGRWLHLRLLNLTNCN 462
L+L+WC IT DG+ LV ++ L L G ++ A +++ L LNL +C+
Sbjct: 160 YLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCS 219
Query: 463 QIDDDLLKTIAR 498
+I D+ + I R
Sbjct: 220 RITDEGVVQICR 231
Score = 51.6 bits (122), Expect = 2e-06
Identities = 54/177 (30%), Positives = 78/177 (44%), Gaps = 5/177 (2%)
Frame = +1
Query: 16 RNCQKLSVLSISYADTFTDNVVLPLRTLSNLKFLSIHKATELSKL--ALLDLFNKPDSQL 189
R C +L L +S TD + L N L I +A S L A L + +L
Sbjct: 231 RGCHRLQALCLSGCSNLTDASLTALGL--NCPRLQILEAARCSHLTDAGFTLLARNCHEL 288
Query: 190 TKLISLDLNECSVIDDEILNSILELCGKNLRILSLNWCWNITDDGLNNLVLVAINMERLS 369
K+ DL EC +I D L + C K L+ LSL+ C ITDDG+ +L ERL
Sbjct: 289 EKM---DLEECILITDSTLIQLSIHCPK-LQALSLSHCELITDDGILHLSNSTCGHERLR 344
Query: 370 LI---GNHIIKGTAFQNLVGRWLHLRLLNLTNCNQIDDDLLKTIARQMPETYIFDYF 531
++ +I A ++L L L L +C Q+ +K + Q+P + YF
Sbjct: 345 VLELDNCLLITDVALEHL-ENCRGLERLELYDCQQVTRAGIKRMRAQLPHVKVHAYF 400
Score = 43.5 bits (101), Expect = 5e-04
Identities = 36/138 (26%), Positives = 64/138 (46%)
Frame = +1
Query: 82 LPLRTLSNLKFLSIHKATELSKLALLDLFNKPDSQLTKLISLDLNECSVIDDEILNSILE 261
L LR S L +++ + ++SK + + + Q L + ++ ++ ++ +I +
Sbjct: 19 LLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQID----VEGRVVENISK 74
Query: 262 LCGKNLRILSLNWCWNITDDGLNNLVLVAINMERLSLIGNHIIKGTAFQNLVGRWLHLRL 441
CG LR LSL C + D L N+E L+L G I + +L L+
Sbjct: 75 RCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKH 134
Query: 442 LNLTNCNQIDDDLLKTIA 495
L+LT+C I + LK I+
Sbjct: 135 LDLTSCVSITNSSLKGIS 152
>sp|P34284|YKK7_CAEEL Hypothetical F-box/LRR-repeat protein C02F5.7
Length = 466
Score = 54.3 bits (129), Expect = 3e-07
Identities = 43/168 (25%), Positives = 81/168 (48%), Gaps = 1/168 (0%)
Frame = +1
Query: 13 LRNCQKLSVLSISYADTFTDNVVLPLRT-LSNLKFLSIHKATELSKLALLDLFNKPDSQL 189
L NC+ L L + + T+NV + + +K L++ + +L+ + + ++ N
Sbjct: 223 LSNCKSLDTLILRGCEGLTENVFGSVEAHMGAIKKLNLLQCFQLTDITVQNIANGA---- 278
Query: 190 TKLISLDLNECSVIDDEILNSILELCGKNLRILSLNWCWNITDDGLNNLVLVAINMERLS 369
T L L ++ C+ I D L S+ + NL++L L+ C + D+G L +ERL
Sbjct: 279 TALEYLCMSNCNQISDRSLVSLGQH-SHNLKVLELSGCTLLGDNGFIPLARGCRQLERLD 337
Query: 370 LIGNHIIKGTAFQNLVGRWLHLRLLNLTNCNQIDDDLLKTIARQMPET 513
+ +I +L LR L+L++C I D+ ++ +A + ET
Sbjct: 338 MEDCSLISDHTINSLANNCTALRELSLSHCELITDESIQNLASKHRET 385
Score = 48.9 bits (115), Expect = 1e-05
Identities = 43/164 (26%), Positives = 73/164 (44%), Gaps = 5/164 (3%)
Frame = +1
Query: 31 LSVLSISYADTFTDNVVLP----LRTLSNLKFLSIHKATELSKLALLDLFNKPDSQLTKL 198
++ LS + D N VLP L+ S L ++ ++ ++ + + + + Q L
Sbjct: 43 ITTLSPAQVDNSLINRVLPKEVLLKVFSFLDTKALCRSAQVCRSWSILALDGSNWQRVDL 102
Query: 199 ISLDLNECSVIDDEILNSILELCGKNLRILSLNWCWNITDDGLNNLVLVAINMERLSLIG 378
+ + + ++ ++ CG L+ LSL C N+ D L N+E LSL
Sbjct: 103 FTFQRD----VKTAVVENLARRCGGFLKELSLKGCENVHDSALRTFTSRCPNLEHLSLYR 158
Query: 379 NHIIKGTAFQNLVGRWLH-LRLLNLTNCNQIDDDLLKTIARQMP 507
+ + +NL GR+ H L LNL NC+ I D +K I P
Sbjct: 159 CKRVTDASCENL-GRYCHKLNYLNLENCSSITDRAMKYIGDGCP 201
Score = 40.8 bits (94), Expect = 0.003
Identities = 47/198 (23%), Positives = 81/198 (40%), Gaps = 30/198 (15%)
Frame = +1
Query: 31 LSVLSISYADTFTDNVVLPLRTLS----NLKFLSIHKATELSKLALLDLFNKPDSQLTKL 198
L LS+ + D+ LRT + NL+ LS+++ ++ + +L KL
Sbjct: 125 LKELSLKGCENVHDSA---LRTFTSRCPNLEHLSLYRCKRVTDASCENL----GRYCHKL 177
Query: 199 ISLDLNECSVIDDEILNSILELCGKNLRILSLNWCWNITDDG----------LNNLVLVA 348
L+L CS I D + I + C NL L+++WC I D G L+ L+L
Sbjct: 178 NYLNLENCSSITDRAMKYIGDGC-PNLSYLNISWCDAIQDRGVQIILSNCKSLDTLILRG 236
Query: 349 IN----------------MERLSLIGNHIIKGTAFQNLVGRWLHLRLLNLTNCNQIDDDL 480
+++L+L+ + QN+ L L ++NCNQI D
Sbjct: 237 CEGLTENVFGSVEAHMGAIKKLNLLQCFQLTDITVQNIANGATALEYLCMSNCNQISDRS 296
Query: 481 LKTIARQMPETYIFDYFG 534
L ++ + + + G
Sbjct: 297 LVSLGQHSHNLKVLELSG 314
>sp|Q9UJT9|FBXL7_HUMAN F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein
7) (F-box protein FBL6/FBL7)
Length = 491
Score = 52.8 bits (125), Expect = 8e-07
Identities = 43/175 (24%), Positives = 85/175 (48%), Gaps = 9/175 (5%)
Frame = +1
Query: 1 GLHALRNC-QKLSVLSISYADTFTDNVVLPLRTLS-NLKFLSIHKATELSKLALLDLFNK 174
GL+ + C +L L +S ++ V + +L NL+ L + + SK+ + L +
Sbjct: 203 GLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDV---SGCSKVTCISLTRE 259
Query: 175 PDSQLTKLIS-------LDLNECSVIDDEILNSILELCGKNLRILSLNWCWNITDDGLNN 333
+L+ L LD+ +C V++DE L++I C + L L L C +TD+GL
Sbjct: 260 ASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQ-LTHLYLRRCVRLTDEGLRY 318
Query: 334 LVLVAINMERLSLIGNHIIKGTAFQNLVGRWLHLRLLNLTNCNQIDDDLLKTIAR 498
LV+ +++ LS+ + + + LR L++ +C ++ D ++ +A+
Sbjct: 319 LVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAK 373
Score = 36.2 bits (82), Expect = 0.075
Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 1/116 (0%)
Frame = +1
Query: 28 KLSVLSISYADTFTD-NVVLPLRTLSNLKFLSIHKATELSKLALLDLFNKPDSQLTKLIS 204
+L LSI++ TD + + S L++L+ ++ + L TKL S
Sbjct: 351 RLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKN----CTKLKS 406
Query: 205 LDLNECSVIDDEILNSILELCGKNLRILSLNWCWNITDDGLNNLVLVAINMERLSL 372
LD+ +C ++ D L + C NL+ LSL C +IT GL + +++ L++
Sbjct: 407 LDIGKCPLVSDTGLECLALNC-FNLKRLSLKSCESITGQGLQIVAANCFDLQTLNV 461
>sp|Q96IG2|FXL20_HUMAN F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein
20) (F-box/LRR-repeat protein 2-like)
Length = 436
Score = 52.4 bits (124), Expect = 1e-06
Identities = 48/177 (27%), Positives = 81/177 (45%), Gaps = 5/177 (2%)
Frame = +1
Query: 16 RNCQKLSVLSISYADTFTDNVVLPL-RTLSNLKFLSIHKATELSKLALLDLFNKPDSQLT 192
R C KL L S TD ++ L + L+ L + + ++L+ + L
Sbjct: 244 RGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARN----CH 299
Query: 193 KLISLDLNECSVIDDEILNSILELCGKNLRILSLNWCWNITDDGLNNLVLVAINMERLSL 372
+L +DL EC I D L + C + L++LSL+ C ITDDG+ +L A ++L +
Sbjct: 300 ELEKMDLEECVQITDSTLIQLSIHCPR-LQVLSLSHCELITDDGIRHLGNGACAHDQLEV 358
Query: 373 I---GNHIIKGTAFQNLVGRWLH-LRLLNLTNCNQIDDDLLKTIARQMPETYIFDYF 531
I +I + ++L + H L + L +C QI +K + +P + YF
Sbjct: 359 IELDNCPLITDASLEHL--KSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYF 413
Score = 49.3 bits (116), Expect = 9e-06
Identities = 39/132 (29%), Positives = 63/132 (47%)
Frame = +1
Query: 103 NLKFLSIHKATELSKLALLDLFNKPDSQLTKLISLDLNECSVIDDEILNSILELCGKNLR 282
N++ L+++ T+ + L +KL LDL C+ I + L ++ E C L
Sbjct: 118 NIEVLNLNGCTKTTDATCTSL----SKFCSKLRHLDLASCTSITNMSLKALSEGCPL-LE 172
Query: 283 ILSLNWCWNITDDGLNNLVLVAINMERLSLIGNHIIKGTAFQNLVGRWLHLRLLNLTNCN 462
L+++WC +T DG+ LV ++ L L G ++ A + + L LNL C
Sbjct: 173 QLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCL 232
Query: 463 QIDDDLLKTIAR 498
QI D+ L TI R
Sbjct: 233 QITDEGLITICR 244
Score = 46.2 bits (108), Expect = 7e-05
Identities = 48/188 (25%), Positives = 77/188 (40%), Gaps = 23/188 (12%)
Frame = +1
Query: 16 RNCQKLSVLSISYADTFTDNVVLPL-RTLSNLKFLSIHKATELSKLALLDLFNKPD---- 180
+NC+ + VL+++ TD L + S L+ L + T ++ ++L L
Sbjct: 114 QNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQ 173
Query: 181 ------SQLTK------------LISLDLNECSVIDDEILNSILELCGKNLRILSLNWCW 306
Q+TK L +L L C+ ++DE L I C + L L+L C
Sbjct: 174 LNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPE-LVTLNLQTCL 232
Query: 307 NITDDGLNNLVLVAINMERLSLIGNHIIKGTAFQNLVGRWLHLRLLNLTNCNQIDDDLLK 486
ITD+GL + ++ L G I L LR+L + C+Q+ D
Sbjct: 233 QITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFT 292
Query: 487 TIARQMPE 510
T+AR E
Sbjct: 293 TLARNCHE 300
Score = 38.5 bits (88), Expect = 0.015
Identities = 27/93 (29%), Positives = 42/93 (45%)
Frame = +1
Query: 229 IDDEILNSILELCGKNLRILSLNWCWNITDDGLNNLVLVAINMERLSLIGNHIIKGTAFQ 408
I+ ++ +I + CG LR LSL C + D+ L N+E L+L G
Sbjct: 77 IEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCT 136
Query: 409 NLVGRWLHLRLLNLTNCNQIDDDLLKTIARQMP 507
+L LR L+L +C I + LK ++ P
Sbjct: 137 SLSKFCSKLRHLDLASCTSITNMSLKALSEGCP 169
>sp|Q9QZH7|FXL20_RAT F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein
20) (F-box/LRR-repeat protein 2-like)
Length = 276
Score = 50.4 bits (119), Expect = 4e-06
Identities = 40/132 (30%), Positives = 63/132 (47%)
Frame = +1
Query: 103 NLKFLSIHKATELSKLALLDLFNKPDSQLTKLISLDLNECSVIDDEILNSILELCGKNLR 282
N++ LS++ T+ + L +KL LDL C+ I + L ++ E C L
Sbjct: 118 NIEVLSLNGCTKTTDATCTSL----SKFCSKLRHLDLASCTSITNMSLKALSEGCPL-LE 172
Query: 283 ILSLNWCWNITDDGLNNLVLVAINMERLSLIGNHIIKGTAFQNLVGRWLHLRLLNLTNCN 462
L+++WC +T DG+ LV ++ L L G ++ A + + L LNL C
Sbjct: 173 QLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCL 232
Query: 463 QIDDDLLKTIAR 498
QI D+ L TI R
Sbjct: 233 QITDEGLITICR 244
Score = 39.7 bits (91), Expect = 0.007
Identities = 28/93 (30%), Positives = 42/93 (45%)
Frame = +1
Query: 229 IDDEILNSILELCGKNLRILSLNWCWNITDDGLNNLVLVAINMERLSLIGNHIIKGTAFQ 408
I+ ++ +I + CG LR LSL C + D+ L N+E LSL G
Sbjct: 77 IEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLSLNGCTKTTDATCT 136
Query: 409 NLVGRWLHLRLLNLTNCNQIDDDLLKTIARQMP 507
+L LR L+L +C I + LK ++ P
Sbjct: 137 SLSKFCSKLRHLDLASCTSITNMSLKALSEGCP 169
>sp|Q9CZV8|FXL20_MOUSE F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein
20) (F-box/LRR-repeat protein 2-like)
Length = 436
Score = 50.4 bits (119), Expect = 4e-06
Identities = 40/132 (30%), Positives = 63/132 (47%)
Frame = +1
Query: 103 NLKFLSIHKATELSKLALLDLFNKPDSQLTKLISLDLNECSVIDDEILNSILELCGKNLR 282
N++ LS++ T+ + L +KL LDL C+ I + L ++ E C L
Sbjct: 118 NIEVLSLNGCTKTTDATCTSL----SKFCSKLRHLDLASCTSITNMSLKALSEGCPL-LE 172
Query: 283 ILSLNWCWNITDDGLNNLVLVAINMERLSLIGNHIIKGTAFQNLVGRWLHLRLLNLTNCN 462
L+++WC +T DG+ LV ++ L L G ++ A + + L LNL C
Sbjct: 173 QLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCL 232
Query: 463 QIDDDLLKTIAR 498
QI D+ L TI R
Sbjct: 233 QITDEGLITICR 244
Score = 50.4 bits (119), Expect = 4e-06
Identities = 46/176 (26%), Positives = 78/176 (44%), Gaps = 4/176 (2%)
Frame = +1
Query: 16 RNCQKLSVLSISYADTFTDNVVLPL-RTLSNLKFLSIHKATELSKLALLDLFNKPDSQLT 192
R C KL L S TD ++ L + L+ L + + ++L+ + L
Sbjct: 244 RGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARN----CH 299
Query: 193 KLISLDLNECSVIDDEILNSILELCGKNLRILSLNWCWNITDDGLNNLVLVAINMERLSL 372
+L +DL EC I D L + C + L++LSL+ C ITDDG+ +L A ++L +
Sbjct: 300 ELEKMDLEECVQITDSTLIQLSIHCPR-LQVLSLSHCELITDDGIRHLGNGACAHDQLEV 358
Query: 373 I---GNHIIKGTAFQNLVGRWLHLRLLNLTNCNQIDDDLLKTIARQMPETYIFDYF 531
I +I + ++L + L +C QI +K + +P + YF
Sbjct: 359 IELDNCPLITDASLEHLKS-CPSFERIELYDCQQITRAGIKRLRTHLPNIKVHAYF 413
Score = 47.4 bits (111), Expect = 3e-05
Identities = 49/188 (26%), Positives = 77/188 (40%), Gaps = 23/188 (12%)
Frame = +1
Query: 16 RNCQKLSVLSISYADTFTDNVVLPL-RTLSNLKFLSIHKATELSKLALLDLFNKPD---- 180
+NC+ + VLS++ TD L + S L+ L + T ++ ++L L
Sbjct: 114 QNCRNIEVLSLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQ 173
Query: 181 ------SQLTK------------LISLDLNECSVIDDEILNSILELCGKNLRILSLNWCW 306
Q+TK L +L L C+ ++DE L I C + L L+L C
Sbjct: 174 LNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPE-LVTLNLQTCL 232
Query: 307 NITDDGLNNLVLVAINMERLSLIGNHIIKGTAFQNLVGRWLHLRLLNLTNCNQIDDDLLK 486
ITD+GL + ++ L G I L LR+L + C+Q+ D
Sbjct: 233 QITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFT 292
Query: 487 TIARQMPE 510
T+AR E
Sbjct: 293 TLARNCHE 300
Score = 39.7 bits (91), Expect = 0.007
Identities = 28/93 (30%), Positives = 42/93 (45%)
Frame = +1
Query: 229 IDDEILNSILELCGKNLRILSLNWCWNITDDGLNNLVLVAINMERLSLIGNHIIKGTAFQ 408
I+ ++ +I + CG LR LSL C + D+ L N+E LSL G
Sbjct: 77 IEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLSLNGCTKTTDATCT 136
Query: 409 NLVGRWLHLRLLNLTNCNQIDDDLLKTIARQMP 507
+L LR L+L +C I + LK ++ P
Sbjct: 137 SLSKFCSKLRHLDLASCTSITNMSLKALSEGCP 169
>sp|Q8WV35|LRC29_HUMAN Leucine-rich repeat-containing protein 29 (F-box/LRR-repeat protein
9) (F-box and leucine-rich repeat protein 9) (F-box
protein FBL9)
Length = 223
Score = 46.6 bits (109), Expect = 6e-05
Identities = 32/113 (28%), Positives = 53/113 (46%)
Frame = +1
Query: 187 LTKLISLDLNECSVIDDEILNSILELCGKNLRILSLNWCWNITDDGLNNLVLVAINMERL 366
L L LDL CS + D L +L+ LR LSL+ +TD+GL + ++E L
Sbjct: 74 LRALQELDLTACSKLTDASLAKVLQFL--QLRQLSLSLLPELTDNGLVAVARGCPSLEHL 131
Query: 367 SLIGNHIIKGTAFQNLVGRWLHLRLLNLTNCNQIDDDLLKTIARQMPETYIFD 525
+L + + W L+ LNL++C+Q+ + L I + + + D
Sbjct: 132 ALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLD 184
>sp|Q8NEE6|FXL13_HUMAN F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein
13)
Length = 735
Score = 46.2 bits (108), Expect = 7e-05
Identities = 43/171 (25%), Positives = 76/171 (44%), Gaps = 11/171 (6%)
Frame = +1
Query: 13 LRNCQKLSVLSISYADTFTDNV-VLPLRTLSNLKFLSIHKATELSKLALLDLFNKPDS-- 183
L NC +LS S+ N+ L LR +L I + L +DL S
Sbjct: 486 LSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNIFSLVSIDLSGTDISNE 545
Query: 184 ------QLTKLISLDLNECSVIDDEILNSILELCGKNLRI--LSLNWCWNITDDGLNNLV 339
+ KL L ++EC I D+ I C +L + L +++C ++D + L
Sbjct: 546 GLNVLSRHKKLKELSVSECYRITDD---GIQAFCKSSLILEHLDVSYCSQLSDMIIKALA 602
Query: 340 LVAINMERLSLIGNHIIKGTAFQNLVGRWLHLRLLNLTNCNQIDDDLLKTI 492
+ IN+ LS+ G I +A + L + +L +L+++ C + D +L+ +
Sbjct: 603 IYCINLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDL 653
Score = 37.0 bits (84), Expect = 0.044
Identities = 29/96 (30%), Positives = 48/96 (50%), Gaps = 1/96 (1%)
Frame = +1
Query: 31 LSVLSISYADTFTDNVVLPLRTLS-NLKFLSIHKATELSKLALLDLFNKPDSQLTKLISL 207
L L +SY +D ++ L NL LSI +++ A+ L ++ L L
Sbjct: 582 LEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPKITDSAMEML----SAKCHYLHIL 637
Query: 208 DLNECSVIDDEILNSILELCGKNLRILSLNWCWNIT 315
D++ C ++ D+IL + C K LRIL + +C NI+
Sbjct: 638 DISGCVLLTDQILEDLQIGC-KQLRILKMQYCTNIS 672
Score = 30.0 bits (66), Expect = 5.4
Identities = 40/172 (23%), Positives = 72/172 (41%), Gaps = 9/172 (5%)
Frame = +1
Query: 19 NCQKLSVLSISYADTFTDNVVLPLRTLSNLKFLSIHKATELSKLALLDLFNKPDSQLTKL 198
+C + L+I+ T TDN V L + K + ++ L + D L
Sbjct: 348 SCTGIMHLTINDMPTLTDNCVKAL----------VEKCSRITSLVFTGAPHISDCTFRAL 397
Query: 199 ISLDLNECSVIDDE-ILNSILELCGKNLRILSLNW---CWNITDDGLNNLV----LVAIN 354
+ L + ++ + ++ + KN LS + C ITD L +L L +N
Sbjct: 398 SACKLRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSPLKQLTVLN 457
Query: 355 MERLSLIGNHIIKGTAFQNLVG-RWLHLRLLNLTNCNQIDDDLLKTIARQMP 507
+ IG+ +K Q L G + +R LNL+NC ++ D + ++ + P
Sbjct: 458 LANCVRIGDMGLK----QFLDGPASMRIRELNLSNCVRLSDASVMKLSERCP 505
>sp|Q8CDU4|FXL13_MOUSE F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein
13)
Length = 790
Score = 45.1 bits (105), Expect = 2e-04
Identities = 41/166 (24%), Positives = 76/166 (45%), Gaps = 23/166 (13%)
Frame = +1
Query: 67 TDNVVLPLRTLSNLKFLSIHKATELSKLALLDLFNKPDSQLTKLISLDLNECSVIDDEIL 246
TD+ + L L L L++ + + L F+ P S +L L+L CS++ D +
Sbjct: 491 TDSSLKSLSLLKQLTVLNLTNCIRIGDIGLKHFFDGPAS--IRLRELNLTNCSLLGDSSV 548
Query: 247 NSILELCGKNLRILSLNWCWNITDDGL----NNLVLVAINM-------ERLSLIGNHI-- 387
+ E C NL L+L C ++TD + + L L+++++ E ++++ H
Sbjct: 549 IRLSERC-PNLHYLNLRNCEHLTDLAIEYIASMLSLISVDLSGTLISNEGMTILSRHRKL 607
Query: 388 ----------IKGTAFQNLVGRWLHLRLLNLTNCNQIDDDLLKTIA 495
I + L L L+++ C+Q+ DD++KTIA
Sbjct: 608 REVSVSDCVNITDFGIRAYCKTSLLLEHLDVSYCSQLTDDIIKTIA 653
Score = 41.2 bits (95), Expect = 0.002
Identities = 36/162 (22%), Positives = 72/162 (44%), Gaps = 2/162 (1%)
Frame = +1
Query: 13 LRNCQKLSVLSISYADTFTDNVVLPLRTLSNLKFLSIHKATELSKLALLDLFNKPDSQLT 192
LRNC+ L+ L+I Y + + + L T +S + L S+
Sbjct: 563 LRNCEHLTDLAIEYIASMLSLISVDL------------SGTLISNEGMTIL-----SRHR 605
Query: 193 KLISLDLNECSVIDDEILNSILELCGKNLRI--LSLNWCWNITDDGLNNLVLVAINMERL 366
KL + +++C I D I C +L + L +++C +TDD + + + + L
Sbjct: 606 KLREVSVSDCVNITDF---GIRAYCKTSLLLEHLDVSYCSQLTDDIIKTIAIFCTRITSL 662
Query: 367 SLIGNHIIKGTAFQNLVGRWLHLRLLNLTNCNQIDDDLLKTI 492
++ G I + L R +L +L+++ C Q+ D +++ +
Sbjct: 663 NIAGCPKITDAGMEILSARCHYLHILDISGCIQLTDQIIQDL 704
Score = 37.0 bits (84), Expect = 0.044
Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Frame = +1
Query: 217 ECSVIDDEILNSILELCGKNLRILSLNWCWNITDDGLNNLV--LVAINMERLSLIGNHII 390
+C + D L S+ L K L +L+L C I D GL + +I + L+L ++
Sbjct: 486 DCKGLTDSSLKSLSLL--KQLTVLNLTNCIRIGDIGLKHFFDGPASIRLRELNLTNCSLL 543
Query: 391 KGTAFQNLVGRWLHLRLLNLTNCNQIDDDLLKTIARQM 504
++ L R +L LNL NC + D ++ IA +
Sbjct: 544 GDSSVIRLSERCPNLHYLNLRNCEHLTDLAIEYIASML 581
Score = 36.2 bits (82), Expect = 0.075
Identities = 47/193 (24%), Positives = 76/193 (39%), Gaps = 26/193 (13%)
Frame = +1
Query: 16 RNCQKLSVLSISYADTFTDNVVLPLRT-----------LSNLKFLSIHKATELSKLALLD 162
R L LS++Y FTD + L LS + + K +S + L+
Sbjct: 377 RYFHNLQNLSLAYCRKFTDKGLQYLNLGNGCHKLIYLDLSGCTQVLVEKCPRISSVVLIG 436
Query: 163 LFNKPDSQLTKLISLDLNECSVIDDEILNSILELCGKNL-------RILSLNWCWNITDD 321
+ DS L S DL + I E I + C K++ + + C +TD
Sbjct: 437 SPHISDSAFKALSSCDLKK---IRFEGNKRISDACFKSIDRNYPGINHIYMVDCKGLTDS 493
Query: 322 GLNNLVLV----AINMERLSLIGN----HIIKGTAFQNLVGRWLHLRLLNLTNCNQIDDD 477
L +L L+ +N+ IG+ H G A + LR LNLTNC+ + D
Sbjct: 494 SLKSLSLLKQLTVLNLTNCIRIGDIGLKHFFDGPAS-------IRLRELNLTNCSLLGDS 546
Query: 478 LLKTIARQMPETY 516
+ ++ + P +
Sbjct: 547 SVIRLSERCPNLH 559
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,433,463
Number of Sequences: 369166
Number of extensions: 1157204
Number of successful extensions: 3214
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3068
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3163
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5316264630
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)