Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_I03
(925 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q99PL6|UBXD1_MOUSE UBX domain-containing protein 1 118 3e-26
sp|Q9BZV1|UBXD1_HUMAN UBX domain-containing protein 1 109 1e-23
sp|P41541|VDP_BOVIN General vesicular transport factor p115... 38 0.035
sp|O60763|VDP_HUMAN General vesicular transport factor p115... 38 0.046
sp|Q9Z1Z0|VDP_MOUSE General vesicular transport factor p115... 37 0.060
sp|P41542|VDP_RAT General vesicular transport factor p115 (... 36 0.13
sp|P30622|REST_HUMAN Restin (Cytoplasmic linker protein 170... 35 0.39
sp|Q924T7|RNF31_MOUSE RING finger protein 31 34 0.51
sp|Q96EP0|RNF31_HUMAN RING finger protein 31 (Zinc in-betwe... 33 0.87
sp|Q07866|KLC1_HUMAN Kinesin light chain 1 (KLC 1) 33 1.5
>sp|Q99PL6|UBXD1_MOUSE UBX domain-containing protein 1
Length = 442
Score = 118 bits (295), Expect = 3e-26
Identities = 74/251 (29%), Positives = 130/251 (51%), Gaps = 4/251 (1%)
Frame = +1
Query: 100 VEKPKQLSKVYFCCPSLFDYDIIGGY----HEMEAKIFSYLESEAVENSLLASCLIIHSK 267
V +PK+ + P +F + G + +A I + S + + AS + IH+
Sbjct: 105 VPEPKEEISPHLAVPGVFFICPLTGVTLRRDQRDAHIKQAILSHFSTDPVAASIMKIHTF 164
Query: 268 CKNQVLLETCLKILETLIKNIIQSPNEPKFRKIRLENERIKQNIVQVEGAIDFLKAIGFV 447
+++ ++ + + + NI P E K++KI+L+N+ ++ I +EG+ +F +AIGF
Sbjct: 165 NRDRDRVKLGVDTIAKYLDNIHLHPEEEKYQKIKLQNKVFQERINCLEGSHEFFEAIGFK 224
Query: 448 SEDQLKPGSTDEMETCLVMPDEACIPERLTEYLANLKDAEPIKPVLYRDSNVFHKQNLVH 627
P + E ++ D P+ L + L DAEP++ L R VF L
Sbjct: 225 KVTLPVPDQEGQEEFYVLGEDARAQPQNLARHKQQLLDAEPVRATLDRQLRVFRPSALA- 283
Query: 628 ITEEDLPAEFFRISIEELKRQNQIRKQQIEESGMLLTKTMRENMKIRDKRKYRYVLIRII 807
+ +LP++FF ++ EE+KR+ ++R + +E L TK MRE + R+ RKY Y L+R+
Sbjct: 284 -SHFELPSDFFSLTAEEVKREQRLRTEAVERLSSLRTKAMREKEEQRELRKYTYALVRVR 342
Query: 808 FPNNWVLQGTF 840
P+ +LQGTF
Sbjct: 343 LPDGCLLQGTF 353
>sp|Q9BZV1|UBXD1_HUMAN UBX domain-containing protein 1
Length = 441
Score = 109 bits (272), Expect = 1e-23
Identities = 65/200 (32%), Positives = 107/200 (53%)
Frame = +1
Query: 241 ASCLIIHSKCKNQVLLETCLKILETLIKNIIQSPNEPKFRKIRLENERIKQNIVQVEGAI 420
AS + I++ K+Q ++ + + + NI P E K+RKI+L+N+ ++ I +EG
Sbjct: 156 ASIMKIYTFNKDQDRVKLGVDTIAKYLDNIHLHPEEEKYRKIKLQNKVFQERINCLEGTH 215
Query: 421 DFLKAIGFVSEDQLKPGSTDEMETCLVMPDEACIPERLTEYLANLKDAEPIKPVLYRDSN 600
+F +AIGF D E ++ P+ L + L AEP++ L R
Sbjct: 216 EFFEAIGFQKVLLPAQDQEDPEEFYVLSETTLAQPQSLERHKEQLLAAEPVRAKLDRQRR 275
Query: 601 VFHKQNLVHITEEDLPAEFFRISIEELKRQNQIRKQQIEESGMLLTKTMRENMKIRDKRK 780
VF L ++ +LP +FF ++ EE+KR+ ++R + +E +L TK MRE + R RK
Sbjct: 276 VFQPSPLA--SQFELPGDFFNLTAEEIKREQRLRSEAVERLSVLRTKAMREKEEQRGLRK 333
Query: 781 YRYVLIRIIFPNNWVLQGTF 840
Y Y L+R+ P+ +LQGTF
Sbjct: 334 YNYTLLRVRLPDGCLLQGTF 353
>sp|P41541|VDP_BOVIN General vesicular transport factor p115 (Transcytosis associated
protein) (TAP) (Vesicle docking protein)
Length = 961
Score = 38.1 bits (87), Expect = 0.035
Identities = 31/122 (25%), Positives = 55/122 (45%), Gaps = 16/122 (13%)
Frame = +1
Query: 379 ERIKQNIVQVEGAIDFLKAIGFVSEDQLKPGSTDEMETCLVMPDEACIPERLTEYLANL- 555
E++KQ I + G +F++ +GF+S+ +L ++ + + P+ T+ + L
Sbjct: 562 EKLKQLIEKRIGKENFIEKLGFISKHELYSRASQKPQPNFPSPEYMIFDHEFTKLVKELE 621
Query: 556 ---------------KDAEPIKPVLYRDSNVFHKQNLVHITEEDLPAEFFRISIEELKRQ 690
K+ E K + DS V H +N+ I E+DL E + I LK Q
Sbjct: 622 GVITKAIYKSSEEDKKEEEVKKTLEQHDSIVTHYKNM--IREQDLQLEELKQQISTLKCQ 679
Query: 691 NQ 696
N+
Sbjct: 680 NE 681
>sp|O60763|VDP_HUMAN General vesicular transport factor p115 (Transcytosis associated
protein) (TAP) (Vesicle docking protein)
Length = 962
Score = 37.7 bits (86), Expect = 0.046
Identities = 30/122 (24%), Positives = 55/122 (45%), Gaps = 16/122 (13%)
Frame = +1
Query: 379 ERIKQNIVQVEGAIDFLKAIGFVSEDQLKPGSTDEMETCLVMPDEACIPERLTEYLANL- 555
E++KQ I + G +F++ +GF+S+ +L ++ + + P+ T+ + L
Sbjct: 562 EKLKQLIEKRIGKENFIEKLGFISKHELYSRASQKPQPNFPSPEYMIFDHEFTKLVKELE 621
Query: 556 ---------------KDAEPIKPVLYRDSNVFHKQNLVHITEEDLPAEFFRISIEELKRQ 690
K+ E K + D+ V H +N+ I E+DL E R + LK Q
Sbjct: 622 GVITKAIYKSSEEDKKEEEVKKTLEQHDNIVTHYKNM--IREQDLQLEELRQQVSTLKCQ 679
Query: 691 NQ 696
N+
Sbjct: 680 NE 681
>sp|Q9Z1Z0|VDP_MOUSE General vesicular transport factor p115 (Transcytosis associated
protein) (TAP) (Vesicle docking protein)
Length = 941
Score = 37.4 bits (85), Expect = 0.060
Identities = 33/133 (24%), Positives = 59/133 (44%), Gaps = 19/133 (14%)
Frame = +1
Query: 355 FRKIRLEN---ERIKQNIVQVEGAIDFLKAIGFVSEDQLKPGSTDEMETCLVMPDEACIP 525
F LEN E++KQ I + G +F++ +GF+S+ +L ++ + + P+
Sbjct: 533 FNDNSLENYTKEKLKQLIEKRIGKENFIEKLGFISKHELYSRASQKPQPNFPSPEYMIFD 592
Query: 526 ERLTEYLANL----------------KDAEPIKPVLYRDSNVFHKQNLVHITEEDLPAEF 657
T+ + L K+ E K + D+ V H +N+ I E+DL E
Sbjct: 593 HEFTKLVKELEGVITKAIYKSSEEDKKEEEVKKTLEQHDNIVTHYKNM--IREQDLQLEE 650
Query: 658 FRISIEELKRQNQ 696
+ + LK QN+
Sbjct: 651 LKQQVSTLKCQNE 663
>sp|P41542|VDP_RAT General vesicular transport factor p115 (Transcytosis associated
protein) (TAP) (Vesicle docking protein)
Length = 959
Score = 36.2 bits (82), Expect = 0.13
Identities = 32/133 (24%), Positives = 59/133 (44%), Gaps = 19/133 (14%)
Frame = +1
Query: 355 FRKIRLEN---ERIKQNIVQVEGAIDFLKAIGFVSEDQLKPGSTDEMETCLVMPDEACIP 525
F LEN E++KQ I + G ++++ +GF+S+ +L ++ + + P+
Sbjct: 551 FNDNSLENYTKEKLKQLIEKRIGKENYIEKLGFISKHELYSRASQKPQPNFPSPEYMIFD 610
Query: 526 ERLTEYLANL----------------KDAEPIKPVLYRDSNVFHKQNLVHITEEDLPAEF 657
T+ + L K+ E K + D+ V H +N+ I E+DL E
Sbjct: 611 HEFTKLVKELEGVITKAIYKSSEEDKKEEEVKKTLEQHDNIVTHYKNM--IREQDLQLEE 668
Query: 658 FRISIEELKRQNQ 696
+ + LK QN+
Sbjct: 669 LKQQVSTLKCQNE 681
>sp|P30622|REST_HUMAN Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170)
(Reed-Sternberg intermediate filament associated protein)
(Cytoplasmic linker protein 1)
Length = 1427
Score = 34.7 bits (78), Expect = 0.39
Identities = 41/168 (24%), Positives = 69/168 (41%), Gaps = 10/168 (5%)
Frame = +1
Query: 301 KILETLIKNIIQSPNEPKFRKIRLENERIKQNIVQVEGAIDFLKAIGFVSEDQLKPGSTD 480
+IL+ L K ++ + E K + R EN + Q + ++ D KA + D
Sbjct: 1031 EILQNLQKTLLDT--EDKLKGAREENSGLLQELEELRKQADKAKAA---------QTAED 1079
Query: 481 EMETCLVMPDEACIPERLTEYLANLKDAEPIKPVLYRDSNVFHKQNLVHITE-------- 636
M+ M E TE LA+L+D + L + + + NL ++ E
Sbjct: 1080 AMQIMEQMTKEK------TETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELL 1133
Query: 637 --EDLPAEFFRISIEELKRQNQIRKQQIEESGMLLTKTMRENMKIRDK 774
E+ E FR IE LK+ + QQ L+ EN+K+ ++
Sbjct: 1134 TVENQKMEEFRKEIETLKQAAAQKSQQ-------LSALQEENVKLAEE 1174
>sp|Q924T7|RNF31_MOUSE RING finger protein 31
Length = 1066
Score = 34.3 bits (77), Expect = 0.51
Identities = 20/67 (29%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Frame = +1
Query: 259 HSKCKNQV-LLETCLKILETLIKNIIQSPNEPKF-RKIRLENERIKQNIVQVEGAIDFLK 432
H + +N + L T L ILE +N++ SP P++ R ++ N + + V+G D L+
Sbjct: 61 HGEPRNYLNTLSTALNILEKYGRNLL-SPQRPRYWRSVKFNNPVFRSTVDAVQGGRDVLR 119
Query: 433 AIGFVSE 453
G+ E
Sbjct: 120 LYGYTEE 126
>sp|Q96EP0|RNF31_HUMAN RING finger protein 31 (Zinc in-between-RING-finger
ubiquitin-associated domain protein)
Length = 1072
Score = 33.5 bits (75), Expect = 0.87
Identities = 20/67 (29%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Frame = +1
Query: 259 HSKCKNQV-LLETCLKILETLIKNIIQSPNEPKF-RKIRLENERIKQNIVQVEGAIDFLK 432
H + +N + L T L ILE +N++ SP P++ R ++ N + + V+G D L+
Sbjct: 62 HGEPRNYLNTLSTALNILEKYGRNLL-SPQRPRYWRGVKFNNPVFRSTVDAVQGGRDVLR 120
Query: 433 AIGFVSE 453
G+ E
Sbjct: 121 LYGYTEE 127
>sp|Q07866|KLC1_HUMAN Kinesin light chain 1 (KLC 1)
Length = 569
Score = 32.7 bits (73), Expect = 1.5
Identities = 29/115 (25%), Positives = 51/115 (44%), Gaps = 5/115 (4%)
Frame = +1
Query: 58 AYDLRERAFGKEVIVEKPKQLSKVYFCCPSLFDYDIIGGYHEMEAKIFSYL-----ESEA 222
A ++RE+ GK+ + KQL+ + C + Y+ + Y++ +I+ + A
Sbjct: 319 ALEIREKVLGKDH-PDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVA 377
Query: 223 VENSLLASCLIIHSKCKNQVLLETCLKILETLIKNIIQSPNEPKFRKIRLENERI 387
+ LASC + K K ETL K I+ +E +F + EN+ I
Sbjct: 378 KTKNNLASCYLKQGKFKQA----------ETLYKEILTRAHEREFGSVDDENKPI 422
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,190,348
Number of Sequences: 369166
Number of extensions: 1805000
Number of successful extensions: 4946
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4761
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4941
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9462723610
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)