Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_H24
(522 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P40629|ZEF2_IRV6 Zinc finger protein 44 2e-04
sp|Q24307|IAP2_DROME Apoptosis 2 inhibitor (Inhibitor of ap... 40 0.003
sp|Q9VUX2|MIB_DROME Ubiquitin ligase protein mind-bomb (Min... 39 0.008
sp|Q13490|BIRC2_HUMAN Baculoviral IAP repeat-containing pro... 36 0.049
sp|Q13489|BIRC3_HUMAN Baculoviral IAP repeat-containing pro... 36 0.064
sp|Q62210|BIRC2_MOUSE Baculoviral IAP repeat-containing pro... 36 0.064
sp|Q80ZI6|LRSM1_MOUSE Ubiquitin ligase protein LRSAM1 (Leuc... 36 0.064
sp|Q90660|BIR_CHICK Inhibitor of apoptosis protein (IAP) (I... 36 0.064
sp|Q6UWE0|LRSM1_HUMAN Ubiquitin ligase protein LRSAM1 (Leuc... 35 0.083
sp|Q8WY64|MYLIP_HUMAN Ubiquitin ligase MYLIP (Myosin regula... 35 0.083
>sp|P40629|ZEF2_IRV6 Zinc finger protein
Length = 145
Score = 43.9 bits (102), Expect = 2e-04
Identities = 19/63 (30%), Positives = 34/63 (53%)
Frame = +3
Query: 258 ELEKYLKILDNLESIIFYRLSEISKKFLNCVVCQSDRVSVLYLSCGSVLLCNKCHLATNE 437
E EK+ ++ D L ++ K L C++C +++V +L + CG +++CN C L N
Sbjct: 65 EKEKFNQVEDKLTTL---------SKNLTCIICLTNQVQILTIPCGHLIMCNPCSLNLNN 115
Query: 438 GSC 446
C
Sbjct: 116 SVC 118
>sp|Q24307|IAP2_DROME Apoptosis 2 inhibitor (Inhibitor of apoptosis 2) (dIAP2) (DIAP)
(IAP homolog A) (IAP-like protein) (DILP)
Length = 498
Score = 40.0 bits (92), Expect = 0.003
Identities = 16/44 (36%), Positives = 26/44 (59%)
Frame = +3
Query: 345 CVVCQSDRVSVLYLSCGSVLLCNKCHLATNEGSCRLCKTQIQEF 476
C VC + V V++L CG + CN+C A + +C +C+ I+ F
Sbjct: 451 CKVCLDEEVGVVFLPCGHLATCNQC--APSVANCPMCRADIKGF 492
>sp|Q9VUX2|MIB_DROME Ubiquitin ligase protein mind-bomb (Mind bomb homolog) (D-mib)
Length = 1226
Score = 38.9 bits (89), Expect = 0.008
Identities = 17/48 (35%), Positives = 25/48 (52%)
Frame = +3
Query: 330 KKFLNCVVCQSDRVSVLYLSCGSVLLCNKCHLATNEGSCRLCKTQIQE 473
+K C+VC R +V + CG ++ C C + C LC+TQI E
Sbjct: 1012 EKIDECLVCSDRRAAVFFRPCGHMVACEHCSALMKK--CVLCRTQIDE 1057
>sp|Q13490|BIRC2_HUMAN Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis
protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF
signaling complex protein 2) (IAP homolog B)
Length = 618
Score = 36.2 bits (82), Expect = 0.049
Identities = 21/78 (26%), Positives = 39/78 (50%)
Frame = +3
Query: 225 DERLDKISFYEELEKYLKILDNLESIIFYRLSEISKKFLNCVVCQSDRVSVLYLSCGSVL 404
D L K F ++ KY+ D + +L + ++ C VC VSV+++ CG ++
Sbjct: 532 DSTLYKNLFVDKNMKYIPTEDVSGLSLEEQLRRLQEE-RTCKVCMDKEVSVVFIPCGHLV 590
Query: 405 LCNKCHLATNEGSCRLCK 458
+C +C A + C +C+
Sbjct: 591 VCQEC--APSLRKCPICR 606
>sp|Q13489|BIRC3_HUMAN Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis
protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF
signaling complex protein 1) (IAP homolog C) (Apoptosis
inhibitor 2) (API2)
Length = 604
Score = 35.8 bits (81), Expect = 0.064
Identities = 18/74 (24%), Positives = 39/74 (52%)
Frame = +3
Query: 249 FYEELEKYLKILDNLESIIFYRLSEISKKFLNCVVCQSDRVSVLYLSCGSVLLCNKCHLA 428
F ++ KY+ D + + +L + ++ C VC VS++++ CG +++C C A
Sbjct: 526 FVQQDIKYIPTEDVSDLPVEEQLRRLQEE-RTCKVCMDKEVSIVFIPCGHLVVCKDC--A 582
Query: 429 TNEGSCRLCKTQIQ 470
+ C +C++ I+
Sbjct: 583 PSLRKCPICRSTIK 596
>sp|Q62210|BIRC2_MOUSE Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis
protein 2) (MIAP2) (MIAP-2)
Length = 612
Score = 35.8 bits (81), Expect = 0.064
Identities = 21/82 (25%), Positives = 41/82 (50%)
Frame = +3
Query: 225 DERLDKISFYEELEKYLKILDNLESIIFYRLSEISKKFLNCVVCQSDRVSVLYLSCGSVL 404
D L + F E+ KY+ D + +L + ++ C VC VS++++ CG ++
Sbjct: 526 DSTLYENLFVEKNMKYIPTEDVSGLSLEEQLRRLQEE-RTCKVCMDREVSIVFIPCGHLV 584
Query: 405 LCNKCHLATNEGSCRLCKTQIQ 470
+C +C A + C +C+ I+
Sbjct: 585 VCQEC--APSLRKCPICRGTIK 604
>sp|Q80ZI6|LRSM1_MOUSE Ubiquitin ligase protein LRSAM1 (Leucine-rich repeat and sterile
alpha motif containing 1) (Tsg101-associated ligase)
Length = 727
Score = 35.8 bits (81), Expect = 0.064
Identities = 16/57 (28%), Positives = 28/57 (49%)
Frame = +3
Query: 318 SEISKKFLNCVVCQSDRVSVLYLSCGSVLLCNKCHLATNEGSCRLCKTQIQEFHTLY 488
+E+ CVVC +++L+CG V C +C +C LC+ +I + +Y
Sbjct: 670 AELDMPTSECVVCLEREAQMVFLTCGHVCCCQQCCQPLR--TCPLCRQEISQRLRIY 724
>sp|Q90660|BIR_CHICK Inhibitor of apoptosis protein (IAP) (Inhibitor of T cell apoptosis
protein)
Length = 611
Score = 35.8 bits (81), Expect = 0.064
Identities = 22/82 (26%), Positives = 41/82 (50%)
Frame = +3
Query: 225 DERLDKISFYEELEKYLKILDNLESIIFYRLSEISKKFLNCVVCQSDRVSVLYLSCGSVL 404
D L K F E+ KY+ D + +L + ++ C VC VS++++ CG ++
Sbjct: 525 DPVLYKDLFVEKSMKYVPTEDVSGLPMEEQLRRLQEE-RTCKVCMDKEVSIVFIPCGHLV 583
Query: 405 LCNKCHLATNEGSCRLCKTQIQ 470
+C +C A + C +C+ I+
Sbjct: 584 VCKEC--APSLRKCPICRGTIK 603
>sp|Q6UWE0|LRSM1_HUMAN Ubiquitin ligase protein LRSAM1 (Leucine-rich repeat and sterile
alpha motif containing 1) (Tsg101-associated ligase)
(hTAL)
Length = 723
Score = 35.4 bits (80), Expect = 0.083
Identities = 16/57 (28%), Positives = 28/57 (49%)
Frame = +3
Query: 318 SEISKKFLNCVVCQSDRVSVLYLSCGSVLLCNKCHLATNEGSCRLCKTQIQEFHTLY 488
+E+ + CVVC +++L+CG V C +C +C LC+ I + +Y
Sbjct: 666 AELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLR--TCPLCRQDIAQRLRIY 720
>sp|Q8WY64|MYLIP_HUMAN Ubiquitin ligase MYLIP (Myosin regulatory light chain interacting
protein) (MIR)
Length = 445
Score = 35.4 bits (80), Expect = 0.083
Identities = 13/53 (24%), Positives = 28/53 (52%)
Frame = +3
Query: 330 KKFLNCVVCQSDRVSVLYLSCGSVLLCNKCHLATNEGSCRLCKTQIQEFHTLY 488
K+ + C+VC + ++ + CG + C C A SC +C+++++ +Y
Sbjct: 382 KEAMLCMVCCEEEINSTFCPCGHTVCCESC--AAQLQSCPVCRSRVEHVQHVY 432
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,756,080
Number of Sequences: 369166
Number of extensions: 1113493
Number of successful extensions: 3120
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3038
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3119
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3452909250
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)