Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_E09
(945 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q12946|FOXF1_HUMAN Forkhead box protein F1 (Forkhead-rel... 161 3e-39
sp|Q12947|FOXF2_HUMAN Forkhead box protein F2 (Forkhead-rel... 160 5e-39
sp|Q61080|FOXF1_MOUSE Forkhead box protein F1 (Forkhead-rel... 160 5e-39
sp|Q61850|FOXC2_MOUSE Forkhead box protein C2 (Forkhead-rel... 117 4e-26
sp|Q64731|FOXL1_MOUSE Forkhead box protein L1 (Forkhead-rel... 116 8e-26
sp|P32030|SLP1_DROME Fork head domain transcription factor ... 115 1e-25
sp|Q12952|FOXL1_HUMAN Forkhead box protein L1 (Forkhead-rel... 115 2e-25
sp|P32031|SLP2_DROME Fork head domain transcription factor ... 115 2e-25
sp|Q12948|FOXC1_HUMAN Forkhead box protein C1 (Forkhead-rel... 114 3e-25
sp|Q99958|FOXC2_HUMAN Forkhead box protein C2 (Forkhead-rel... 114 3e-25
>sp|Q12946|FOXF1_HUMAN Forkhead box protein F1 (Forkhead-related protein FKHL5)
(Forkhead-related transcription factor 1) (FREAC-1)
(Forkhead-related activator-1)
Length = 354
Score = 161 bits (407), Expect = 3e-39
Identities = 72/91 (79%), Positives = 81/91 (89%)
Frame = +1
Query: 520 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQHFPFFQGPYQGWKNSVRHNLSLN 699
R+ EKP SYIALIVMAIQ+SP ++ TLSEIY +LQ FPFF+G YQGWKNSVRHNLSLN
Sbjct: 19 RRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLN 78
Query: 700 ECFIKLPKGIGRPGKGHYWTIDPTAEFMFED 792
ECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct: 79 ECFIKLPKGLGRPGKGHYWTIDPASEFMFEE 109
>sp|Q12947|FOXF2_HUMAN Forkhead box protein F2 (Forkhead-related protein FKHL6)
(Forkhead-related transcription factor 2) (FREAC-2)
(Forkhead-related activator-2)
Length = 444
Score = 160 bits (405), Expect = 5e-39
Identities = 72/91 (79%), Positives = 81/91 (89%)
Frame = +1
Query: 520 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQHFPFFQGPYQGWKNSVRHNLSLN 699
R+ EKP SYIALIVMAIQ+SP ++ TLSEIY +LQ FPFF+G YQGWKNSVRHNLSLN
Sbjct: 96 RRPEKPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLN 155
Query: 700 ECFIKLPKGIGRPGKGHYWTIDPTAEFMFED 792
ECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct: 156 ECFIKLPKGLGRPGKGHYWTIDPASEFMFEE 186
>sp|Q61080|FOXF1_MOUSE Forkhead box protein F1 (Forkhead-related protein FKHL5)
(Forkhead-related transcription factor 1) (FREAC-1)
(Hepatocyte nuclear factor 3 forkhead homolog 8) (HFH-8)
Length = 353
Score = 160 bits (405), Expect = 5e-39
Identities = 72/91 (79%), Positives = 81/91 (89%)
Frame = +1
Query: 520 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQHFPFFQGPYQGWKNSVRHNLSLN 699
R+ EKP SYIALIVMAIQ+SP ++ TLSEIY +LQ FPFF+G YQGWKNSVRHNLSLN
Sbjct: 19 RRPEKPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLN 78
Query: 700 ECFIKLPKGIGRPGKGHYWTIDPTAEFMFED 792
ECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct: 79 ECFIKLPKGLGRPGKGHYWTIDPASEFMFEE 109
>sp|Q61850|FOXC2_MOUSE Forkhead box protein C2 (Forkhead-related protein FKHL14)
(Mesenchyme fork head protein 1) (MFH-1 protein)
(Transcription factor FKH-14)
Length = 494
Score = 117 bits (294), Expect = 4e-26
Identities = 57/133 (42%), Positives = 78/133 (58%)
Frame = +1
Query: 532 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQHFPFFQGPYQGWKNSVRHNLSLNECFI 711
KP SYIALI MAIQ +P +K TL+ IY ++ FPF++ QGW+NS+RHNLSLNECF+
Sbjct: 71 KPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFV 130
Query: 712 KLPKGIGRPGKGHYWTIDPTAEFMFEDXXXXXXXXXXXXKISTRSNSGSAFSKSPYTVTS 891
K+P+ +PGKG YWT+DP + MFE+ K + A K P + T+
Sbjct: 131 KVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVPKDKEERAHLKEPPSTTA 190
Query: 892 VSYNNSSPMMFSP 930
+P+ P
Sbjct: 191 KGAPTGTPVADGP 203
>sp|Q64731|FOXL1_MOUSE Forkhead box protein L1 (Forkhead-related protein FKHL11)
(Transcription factor FKH-6)
Length = 337
Score = 116 bits (291), Expect = 8e-26
Identities = 51/88 (57%), Positives = 66/88 (75%)
Frame = +1
Query: 529 EKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQHFPFFQGPYQGWKNSVRHNLSLNECF 708
+KP SYIALI MAIQ +P ++ TL+ IY ++ FPF+ QGW+NS+RHNLSLNECF
Sbjct: 48 QKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNECF 107
Query: 709 IKLPKGIGRPGKGHYWTIDPTAEFMFED 792
+K+P+ GRPGKG YWT+DP MFE+
Sbjct: 108 VKVpreKGRPGKGSYWTLDPRCLDMFEN 135
>sp|P32030|SLP1_DROME Fork head domain transcription factor slp1 (Sloppy paired locus
protein 1)
Length = 322
Score = 115 bits (289), Expect = 1e-25
Identities = 60/154 (38%), Positives = 94/154 (61%), Gaps = 9/154 (5%)
Frame = +1
Query: 352 SNESDSPMKPTEENTTDLENCSNK---------EDEIKKEKSCERETDDXXXXXXXXXXX 504
S + DSP + + ++ E+ S++ +DE++ + ++E++D
Sbjct: 55 SEDFDSPSRTSTPMSSAAESLSSQNNDKLDVEFDDELEDQLDEDQESEDGNPSKKQKM-- 112
Query: 505 XXTAKRKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQHFPFFQGPYQGWKNSVRH 684
TA ++KP SY ALI+MAIQ SP ++ TL+ IY YL FP+F+ +GW+NS+RH
Sbjct: 113 --TAGSDTKKPPYSYNALIMMAIQDSPEQRLTLNGIYQYLINRFPYFKANKRGWQNSIRH 170
Query: 685 NLSLNECFIKLPKGIGRPGKGHYWTIDPTAEFMF 786
NLSLN+CF K+P+ PGKG+YW +DP+AE +F
Sbjct: 171 NLSLNKCFTKIPRSYDDPGKGNYWILDPSAEEVF 204
>sp|Q12952|FOXL1_HUMAN Forkhead box protein L1 (Forkhead-related protein FKHL11)
(Forkhead-related transcription factor 7) (FREAC-7)
Length = 345
Score = 115 bits (288), Expect = 2e-25
Identities = 50/88 (56%), Positives = 66/88 (75%)
Frame = +1
Query: 529 EKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQHFPFFQGPYQGWKNSVRHNLSLNECF 708
+KP SYIALI MAIQ +P ++ TL+ IY ++ FPF+ QGW+NS+RHNLSLN+CF
Sbjct: 48 QKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCF 107
Query: 709 IKLPKGIGRPGKGHYWTIDPTAEFMFED 792
+K+P+ GRPGKG YWT+DP MFE+
Sbjct: 108 VKVpreKGRPGKGSYWTLDPRCLDMFEN 135
>sp|P32031|SLP2_DROME Fork head domain transcription factor slp2 (Sloppy paired locus
protein 2)
Length = 445
Score = 115 bits (288), Expect = 2e-25
Identities = 63/170 (37%), Positives = 96/170 (56%), Gaps = 9/170 (5%)
Frame = +1
Query: 304 DNELINTNKCEENDYVSN---ESD------SPMKPTEENTTDLENCSNKEDEIKKEKSCE 456
+N L TN D+ + ESD SP N +D + E+ ++++ C+
Sbjct: 97 NNNLNTTNWGSPEDHEAESDPESDLDVTSMSPAPVANPNESDPDEVD--EEFVEEDIECD 154
Query: 457 RETDDXXXXXXXXXXXXXTAKRKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQHF 636
ET D K+ +EKP SY ALI+MAI+ S ++ TL+ IY Y+ +
Sbjct: 155 GETTDGDAENKSNDGKPVKDKKGNEKPPYSYNALIMMAIRQSSEKRLTLNGIYEYIMTNH 214
Query: 637 PFFQGPYQGWKNSVRHNLSLNECFIKLPKGIGRPGKGHYWTIDPTAEFMF 786
P+++ QGW+NS+RHNLSLN+CF+K+P+ PGKG+YW +DP+AE +F
Sbjct: 215 PYYRDNKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSAEDVF 264
>sp|Q12948|FOXC1_HUMAN Forkhead box protein C1 (Forkhead-related protein FKHL7)
(Forkhead-related transcription factor 3) (FREAC-3)
Length = 553
Score = 114 bits (286), Expect = 3e-25
Identities = 50/87 (57%), Positives = 66/87 (75%)
Frame = +1
Query: 532 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQHFPFFQGPYQGWKNSVRHNLSLNECFI 711
KP SYIALI MAIQ +P +K TL+ IY ++ FPF++ QGW+NS+RHNLSLNECF+
Sbjct: 78 KPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNKQGWQNSIRHNLSLNECFV 137
Query: 712 KLPKGIGRPGKGHYWTIDPTAEFMFED 792
K+P+ +PGKG YWT+DP + MFE+
Sbjct: 138 KVPRDDKKPGKGSYWTLDPDSYNMFEN 164
>sp|Q99958|FOXC2_HUMAN Forkhead box protein C2 (Forkhead-related protein FKHL14)
(Mesenchyme fork head protein 1) (MFH-1 protein)
(Transcription factor FKH-14)
Length = 501
Score = 114 bits (286), Expect = 3e-25
Identities = 54/115 (46%), Positives = 72/115 (62%)
Frame = +1
Query: 532 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQHFPFFQGPYQGWKNSVRHNLSLNECFI 711
KP SYIALI MAIQ +P +K TL+ IY ++ FPF++ QGW+NS+RHNLSLNECF+
Sbjct: 72 KPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFV 131
Query: 712 KLPKGIGRPGKGHYWTIDPTAEFMFEDXXXXXXXXXXXXKISTRSNSGSAFSKSP 876
K+P+ +PGKG YWT+DP + MFE+ K ++ A K P
Sbjct: 132 KVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVSKEKEERAHLKEP 186
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.310 0.126 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,826,905
Number of Sequences: 369166
Number of extensions: 1522082
Number of successful extensions: 4092
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3779
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4050
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9798962520
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)