Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_E08-1
(472 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P81439|EQST_ACTEQ Equistatin 54 1e-07
sp|P06882|THYG_RAT Thyroglobulin precursor 53 3e-07
sp|O08710|THYG_MOUSE Thyroglobulin precursor 52 5e-07
sp|P84032|PN16_PHONI Venom protein PN16C3 52 5e-07
sp|P01267|THYG_BOVIN Thyroglobulin precursor 52 9e-07
sp|P01266|THYG_HUMAN Thyroglobulin precursor 51 2e-06
sp|O88322|NID2_MOUSE Nidogen-2 precursor (NID-2) (Entactin-2) 47 3e-05
sp|P31226|SAX_RANCA Saxiphilin precursor (SAX) 44 1e-04
sp|Q14112|NID2_HUMAN Nidogen-2 precursor (NID-2) (Osteonido... 44 2e-04
sp|Q92563|TICN2_HUMAN Testican-2 precursor (SPARC/osteonect... 41 0.002
>sp|P81439|EQST_ACTEQ Equistatin
Length = 199
Score = 54.3 bits (129), Expect = 1e-07
Identities = 35/102 (34%), Positives = 51/102 (50%), Gaps = 8/102 (7%)
Frame = -2
Query: 357 PSCEENGDYKPVQCGESS--CYCSDENGKEIYGFDT----SIELRTYKNCNCAVDRAKNS 196
PSC+ +G + VQC S+ CYC D+ GKE+ G S E R C A +A ++
Sbjct: 90 PSCKADGSFDEVQCCASNGECYCVDKKGKELEGTRQKGRPSCE-RHLSPCEEARLQAHSN 148
Query: 195 GIKTIQLSFNCDKLGNYEKLQC--PLFYCYCADANGKKLPSS 76
++ C + G+Y +QC YC+C D G K+P S
Sbjct: 149 SLRVGMFVPQCLEDGSYNPVQCWPSTGYCWCVDEGGVKVPGS 190
Score = 50.4 bits (119), Expect = 2e-06
Identities = 32/111 (28%), Positives = 56/111 (50%), Gaps = 12/111 (10%)
Frame = -2
Query: 381 NGALDVILPSCEENGDYKPVQCGESS--CYCSDENGKEIYGFDTSIELRTYKNCN----- 223
+G + +P C+E G+++ QC S+ C+C DE+GKEI G ++R +C+
Sbjct: 14 SGLIGAYVPQCKETGEFEEKQCWGSTGYCWCVDEDGKEILG----TKIRGSPDCSRRKAA 69
Query: 222 ---CAVDRAKNSGIKTIQLSFNCDKLGNYEKLQCPLF--YCYCADANGKKL 85
C + +A + +C G+++++QC CYC D GK+L
Sbjct: 70 LTLCQMMQAIIVNVPGWCGPPSCKADGSFDEVQCCASNGECYCVDKKGKEL 120
Score = 41.6 bits (96), Expect = 0.001
Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 8/71 (11%)
Frame = -2
Query: 426 PTCFKKHLN----ARRITKNGALDV--ILPSCEENGDYKPVQCGESS--CYCSDENGKEI 271
P+C ++HL+ AR + +L V +P C E+G Y PVQC S+ C+C DE G ++
Sbjct: 129 PSC-ERHLSPCEEARLQAHSNSLRVGMFVPQCLEDGSYNPVQCWPSTGYCWCVDEGGVKV 187
Query: 270 YGFDTSIELRT 238
G D + T
Sbjct: 188 PGSDVRFKRPT 198
>sp|P06882|THYG_RAT Thyroglobulin precursor
Length = 2768
Score = 53.1 bits (126), Expect = 3e-07
Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 8/105 (7%)
Frame = -2
Query: 360 LPSCEENGDYKPVQCGESSCYCSDENGKEIYGFDTSIELRTYKNC--NCAVDRAKN---S 196
+PSC G Y+ +QC C+C + GKE+ G S + C C RA+ +
Sbjct: 617 VPSCTAEGSYEDIQCYAGECWCVNSQGKEVEGSRVS---GGHPRCPTKCEKQRAQMQNLA 673
Query: 195 GIKTIQLSF---NCDKLGNYEKLQCPLFYCYCADANGKKLPSSST 70
G + SF C G + +QC CYC DA G+ +P + +
Sbjct: 674 GAQPAGSSFFVPTCTSEGYFLPVQCFNSECYCVDAEGQVIPGTQS 718
Score = 46.6 bits (109), Expect = 3e-05
Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 11/106 (10%)
Frame = -2
Query: 369 DVILPSCEENGDYKPVQCGE--SSCYCSDENGKEIYGFDTSIELRTYKNC--NCAVDRAK 202
D +P C E+G ++ VQC SC+C D +G E+ G S +L C C + + +
Sbjct: 47 DEYVPQCSEDGSFQTVQCQNDGQSCWCVDSDGTEVPG---SRQLGRPTACLSFCQLHKQR 103
Query: 201 ---NSGIKTIQLSF--NCDKLGNYEKLQCPL--FYCYCADANGKKL 85
+S I + + C GNY +QC L C+C D G ++
Sbjct: 104 ILLSSYINSTDALYLPQCQDSGNYAPVQCDLQQVQCWCVDTEGMEV 149
Score = 45.8 bits (107), Expect = 5e-05
Identities = 35/142 (24%), Positives = 53/142 (37%), Gaps = 40/142 (28%)
Frame = -2
Query: 360 LPSCEENGDYKPVQCG--ESSCYCSDENGKEIYGF-DTSIELRTYKNCNCAVDRAKNS-G 193
LP C+++G+Y PVQC + C+C D G E+YG R ++C R + G
Sbjct: 118 LPQCQDSGNYAPVQCDLQQVQCWCVDTEGMEVYGTRQQGRPTRCPRSCEIRSRRLLHGVG 177
Query: 192 IKTIQLSFNCDKLGNYEKLQCPLF------------------------------------ 121
K+ CD G + +QC
Sbjct: 178 DKSPP---QCDADGEFMPVQCKFVNTTDMMIFDLIHNYNRFPDAFVTFSAFRNRFPEVSG 234
Query: 120 YCYCADANGKKLPSSSTIYITD 55
YCYCAD+ G++L + + D
Sbjct: 235 YCYCADSQGRELAETGLELLLD 256
Score = 39.7 bits (91), Expect = 0.003
Identities = 16/37 (43%), Positives = 22/37 (59%)
Frame = -2
Query: 360 LPSCEENGDYKPVQCGESSCYCSDENGKEIYGFDTSI 250
+P+C G + PVQC S CYC D G+ I G ++I
Sbjct: 684 VPTCTSEGYFLPVQCFNSECYCVDAEGQVIPGTQSTI 720
Score = 36.2 bits (82), Expect = 0.039
Identities = 25/109 (22%), Positives = 49/109 (44%), Gaps = 5/109 (4%)
Frame = -2
Query: 378 GALDVILPSCEENGDYKPVQCGESSCYCSDENGKEIYGFDTSIELRTYKNCNCAVDRAKN 199
G D+ P C + G+Y Q + +C D + E +T+ + C+ R +
Sbjct: 1100 GPGDLFTPVCLQTGEYVRQQTSGTGAWCVDPSSGEGVPTNTNSSAQCPGLCDALKSRVLS 1159
Query: 198 SGIKTIQLSFN--CDKL-GNYEKLQCPLFY--CYCADANGKKLPSSSTI 67
+ + L + C+ L G + +QC L C+C A+G+++P + +
Sbjct: 1160 ---RKVGLGYTPVCEALDGGFSPVQCDLAQGSCWCVLASGEEVPGTRVV 1205
Score = 35.8 bits (81), Expect = 0.050
Identities = 21/53 (39%), Positives = 28/53 (52%), Gaps = 2/53 (3%)
Frame = -2
Query: 360 LPSCEENGDYKPVQCG-ESSCYCSDENGKEIYGF-DTSIELRTYKNCNCAVDR 208
+PSC +G Y+ VQC E C+C D G EI G L K+ +CA +R
Sbjct: 317 IPSCHRDGHYQTVQCQMERMCWCVDAQGIEIPGTRQQGQPLFCAKDQSCASER 369
Score = 32.3 bits (72), Expect = 0.56
Identities = 36/187 (19%), Positives = 66/187 (35%), Gaps = 77/187 (41%)
Frame = -2
Query: 405 LNARRITKNGALDVILPSCEENGDYKPVQCG----------------------------- 313
+ +RR+ +G D P C+ +G++ PVQC
Sbjct: 167 IRSRRLL-HGVGDKSPPQCDADGEFMPVQCKFVNTTDMMIFDLIHNYNRFPDAFVTFSAF 225
Query: 312 -------ESSCYCSDENGKEIYGFDTSIEL---RTYKNCNCAVDRA----KNSGIKTIQL 175
CYC+D G+E+ +T +EL Y +D+A +++ + +Q
Sbjct: 226 RNRFPEVSGYCYCADSQGREL--AETGLELLLDEIYDTIFAGLDQASTFTQSTMYRILQR 283
Query: 174 SF---------------------------------NCDKLGNYEKLQCPL-FYCYCADAN 97
F +C + G+Y+ +QC + C+C DA
Sbjct: 284 RFLAIQLVISGRFRCPTKCEVEQFTATSFGHPYIPSCHRDGHYQTVQCQMERMCWCVDAQ 343
Query: 96 GKKLPSS 76
G ++P +
Sbjct: 344 GIEIPGT 350
Score = 32.0 bits (71), Expect = 0.73
Identities = 14/45 (31%), Positives = 23/45 (51%)
Frame = -2
Query: 168 NCDKLGNYEKLQCPLFYCYCADANGKKLPSSSTIYITDRNKLKCD 34
+C G+YE +QC C+C ++ GK++ S R KC+
Sbjct: 619 SCTAEGSYEDIQCYAGECWCVNSQGKEVEGSRVSGGHPRCPTKCE 663
Score = 31.6 bits (70), Expect = 0.95
Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 7/58 (12%)
Frame = -2
Query: 417 FKKHLNARRITKNGALDVI-----LPSCEENGDYKPVQC--GESSCYCSDENGKEIYG 265
F + L A NG ++ +P C G ++PVQC G C+C D G+ I G
Sbjct: 1005 FYQKLRASLGESNGTASLLWSGPYMPQCNTIGGWEPVQCHPGTGQCWCVDGWGELIPG 1062
>sp|O08710|THYG_MOUSE Thyroglobulin precursor
Length = 2766
Score = 52.4 bits (124), Expect = 5e-07
Identities = 31/103 (30%), Positives = 46/103 (44%), Gaps = 6/103 (5%)
Frame = -2
Query: 360 LPSCEENGDYKPVQCGESSCYCSDENGKEIYGFDTSIELRTYKNCNCAVDRAKNSGIKTI 181
+PSC G Y+ +QC C+C D GKE+ G R C RA+ + +
Sbjct: 617 VPSCTAGGSYEDIQCYAGECWCVDSRGKELDGSRVR-GGRPRCPTKCEKQRAQMQSLASA 675
Query: 180 Q---LSF---NCDKLGNYEKLQCPLFYCYCADANGKKLPSSST 70
Q SF C + G + +QC CYC D G+ +P + +
Sbjct: 676 QPAGSSFFVPTCTREGYFLPVQCFNSECYCVDTEGQVIPGTQS 718
Score = 46.2 bits (108), Expect = 4e-05
Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 9/101 (8%)
Frame = -2
Query: 360 LPSCEENGDYKPVQCGE--SSCYCSDENGKEIYGFDTSIELRTYKNCNCAVDRAK---NS 196
+P C E+G ++ VQC SC+C D +G+E+ G + T C + + + S
Sbjct: 50 VPQCSEDGSFQTVQCQNDGQSCWCVDSDGREVPG-SRQLGRPTVCLSFCQLHKQRILLGS 108
Query: 195 GIKTIQLSF--NCDKLGNYEKLQCPL--FYCYCADANGKKL 85
I + + C GNY +QC L C+C D G ++
Sbjct: 109 YINSTDALYLPQCQDSGNYAPVQCDLQRVQCWCVDTEGMEV 149
Score = 45.4 bits (106), Expect = 6e-05
Identities = 35/139 (25%), Positives = 54/139 (38%), Gaps = 37/139 (26%)
Frame = -2
Query: 360 LPSCEENGDYKPVQCG--ESSCYCSDENGKEIYG---------FDTSIELRTYKNCNCAV 214
LP C+++G+Y PVQC C+C D G E+YG S E+R + +
Sbjct: 118 LPQCQDSGNYAPVQCDLQRVQCWCVDTEGMEVYGTRQQGRPTRCPRSCEIRNRRLLHGVG 177
Query: 213 DRA-----KNSGIKTIQLSF-------NCDKLGNYEKLQCPLF--------------YCY 112
DR+ + +Q F D + NY + YCY
Sbjct: 178 DRSPPQCTADGEFMPVQCKFVNTTDMMIFDLIHNYNRFPDAFVTFSSFRGRFPEVSGYCY 237
Query: 111 CADANGKKLPSSSTIYITD 55
CAD+ G++L + + D
Sbjct: 238 CADSQGRELAETGLELLLD 256
Score = 39.3 bits (90), Expect = 0.005
Identities = 15/37 (40%), Positives = 22/37 (59%)
Frame = -2
Query: 360 LPSCEENGDYKPVQCGESSCYCSDENGKEIYGFDTSI 250
+P+C G + PVQC S CYC D G+ I G +++
Sbjct: 684 VPTCTREGYFLPVQCFNSECYCVDTEGQVIPGTQSTV 720
Score = 35.4 bits (80), Expect = 0.066
Identities = 14/33 (42%), Positives = 20/33 (60%), Gaps = 1/33 (3%)
Frame = -2
Query: 360 LPSCEENGDYKPVQC-GESSCYCSDENGKEIYG 265
+P C +G Y+ VQC E C+C D G+E+ G
Sbjct: 317 IPRCHRDGHYQTVQCQTEGMCWCVDAQGREVPG 349
Score = 34.7 bits (78), Expect = 0.11
Identities = 16/45 (35%), Positives = 23/45 (51%)
Frame = -2
Query: 168 NCDKLGNYEKLQCPLFYCYCADANGKKLPSSSTIYITDRNKLKCD 34
+C G+YE +QC C+C D+ GK+L S R KC+
Sbjct: 619 SCTAGGSYEDIQCYAGECWCVDSRGKELDGSRVRGGRPRCPTKCE 663
Score = 34.7 bits (78), Expect = 0.11
Identities = 25/109 (22%), Positives = 50/109 (45%), Gaps = 5/109 (4%)
Frame = -2
Query: 378 GALDVILPSCEENGDYKPVQCGESSCYCSDENGKEIYGFDTSIELRTYKNCNCAVDRAKN 199
G D+ +P C + G+Y Q + +C D E +T+ + C+ RA +
Sbjct: 1100 GPGDLFIPVCLQTGEYVRKQTSGTGTWCVDPASGEGMPVNTNGSAQCPGLCDVLKSRALS 1159
Query: 198 SGIKTIQLSFN--CDKL-GNYEKLQCPLFY--CYCADANGKKLPSSSTI 67
+ + L ++ C+ L G + +QC L C+C +G+++P + +
Sbjct: 1160 ---RKVGLGYSPVCEALDGAFSPVQCDLAQGSCWCVLGSGEEVPGTRVV 1205
Score = 33.5 bits (75), Expect = 0.25
Identities = 37/137 (27%), Positives = 59/137 (43%), Gaps = 25/137 (18%)
Frame = -2
Query: 417 FKKHLNARRITKNGALDVI-----LPSCEENGDYKPVQC--GESSCYCSDENGKEIYGFD 259
F + L A +GA ++ +P C G ++PVQC G C+C D G+ I G
Sbjct: 1005 FYQSLRASLGKSDGAASLLWSGPYMPQCNMIGGWEPVQCHAGTGQCWCVDGRGEFIPG-- 1062
Query: 258 TSIELRTYK--NC--NCAVDRA-------------KNSGIKTIQLSFNCDKLGNYEKLQC 130
S+ R+ + C NC + RA +N G + + C + G Y + Q
Sbjct: 1063 -SLMSRSSQMPQCPTNCELSRASGLISAWKQAGPQRNPGPGDLFIPV-CLQTGEYVRKQT 1120
Query: 129 PLFYCYCAD-ANGKKLP 82
+C D A+G+ +P
Sbjct: 1121 SGTGTWCVDPASGEGMP 1137
Score = 30.0 bits (66), Expect = 2.8
Identities = 34/179 (18%), Positives = 59/179 (32%), Gaps = 77/179 (43%)
Frame = -2
Query: 381 NGALDVILPSCEENGDYKPVQCG------------------------------------E 310
+G D P C +G++ PVQC
Sbjct: 174 HGVGDRSPPQCTADGEFMPVQCKFVNTTDMMIFDLIHNYNRFPDAFVTFSSFRGRFPEVS 233
Query: 309 SSCYCSDENGKEIYGFDTSIEL---RTYKNCNCAVDRA----KNSGIKTIQLSF------ 169
CYC+D G+E+ +T +EL Y +D+A +++ + +Q F
Sbjct: 234 GYCYCADSQGREL--AETGLELLLDEIYDTIFAGLDQASTFTQSTMYRILQRRFLAIQLV 291
Query: 168 ---------------------------NCDKLGNYEKLQCPL-FYCYCADANGKKLPSS 76
C + G+Y+ +QC C+C DA G+++P +
Sbjct: 292 ISGRFRCPTKCEVEQFAATRFGHSYIPRCHRDGHYQTVQCQTEGMCWCVDAQGREVPGT 350
>sp|P84032|PN16_PHONI Venom protein PN16C3
Length = 128
Score = 52.4 bits (124), Expect = 5e-07
Identities = 36/123 (29%), Positives = 59/123 (47%), Gaps = 6/123 (4%)
Frame = -2
Query: 384 KNGALDVILPSCEENGDYKPVQCGESS--CYCSDENGKEIYGFDTSIELRTYKNCNCAVD 211
K G + ++P C+EN DY+ +QC E S C C D+ G T + K C C +
Sbjct: 16 KTGTIMKLIPKCKENSDYEELQCYEDSKFCVCYDKKGHAASPISTKV-----KECGCYLK 70
Query: 210 R--AKNSGIKTIQLSFNCDKLGNYEKLQCPLF--YCYCADANGKKLPSSSTIYITDRNKL 43
+ K+SG ++ + C++ G + K Q F C+C D G+++ D + L
Sbjct: 71 QKERKDSGRESAIIP-QCEEDGKWAKKQLWEFNKSCWCVDEKGEQVGKIH----HDCDSL 125
Query: 42 KCD 34
KC+
Sbjct: 126 KCE 128
Score = 37.7 bits (86), Expect = 0.013
Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 19/81 (23%)
Frame = -2
Query: 456 DVVCKEDSNAPTCFKK-----------------HLNARRITKNGALDVILPSCEENGDYK 328
++ C EDS C+ K +L + +G I+P CEE+G +
Sbjct: 35 ELQCYEDSKFCVCYDKKGHAASPISTKVKECGCYLKQKERKDSGRESAIIPQCEEDGKWA 94
Query: 327 PVQCGE--SSCYCSDENGKEI 271
Q E SC+C DE G+++
Sbjct: 95 KKQLWEFNKSCWCVDEKGEQV 115
>sp|P01267|THYG_BOVIN Thyroglobulin precursor
Length = 2769
Score = 51.6 bits (122), Expect = 9e-07
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 6/103 (5%)
Frame = -2
Query: 366 VILPSCEENGDYKPVQCGESSCYCSDENGKEIYGFDTSIELRTYKNCNCAVDRAKNSGIK 187
+ +P+C G Y+ VQC C+C D G+E+ G R C RA+ +
Sbjct: 614 LFVPACTAEGSYEEVQCFAGDCWCVDAQGRELAGSRVR-GGRPRCPTECEKQRARMQSLL 672
Query: 186 TIQLSFN------CDKLGNYEKLQCPLFYCYCADANGKKLPSS 76
Q + + C GN+ +QC CYC D G+ +P +
Sbjct: 673 GSQPAGSSLFVPACTSKGNFLPVQCFNSECYCVDTEGQPIPGT 715
Score = 48.1 bits (113), Expect = 1e-05
Identities = 32/103 (31%), Positives = 54/103 (52%), Gaps = 11/103 (10%)
Frame = -2
Query: 360 LPSCEENGDYKPVQCGE--SSCYCSDENGKEIYGFDTSIELRTYKNC--NCAVDRAK--- 202
+P C E+G ++ VQCG+ +SC+C D +G+E+ G S + C C + + +
Sbjct: 49 VPQCAEDGSFQTVQCGKDGASCWCVDADGREVPG---SRQPGRPAACLSFCQLQKQQILL 105
Query: 201 NSGIKTIQLSF--NCDKLGNYEKLQCPL--FYCYCADANGKKL 85
+S I + S+ C G+Y +QC L C+C DA G ++
Sbjct: 106 SSYINSTATSYLPQCQDSGDYSPVQCDLRRRQCWCVDAEGMEV 148
Score = 47.8 bits (112), Expect = 1e-05
Identities = 37/156 (23%), Positives = 53/156 (33%), Gaps = 47/156 (30%)
Frame = -2
Query: 381 NGALDVILPSCEENGDYKPVQCG--ESSCYCSDENGKEIYG---------FDTSIELRTY 235
N LP C+++GDY PVQC C+C D G E+YG S E+R
Sbjct: 110 NSTATSYLPQCQDSGDYSPVQCDLRRRQCWCVDAEGMEVYGTRQQGRPARCPRSCEIRNR 169
Query: 234 KNCNCAVDRAKNSGIKTIQLSFNCDKLGNYEKLQCPLF---------------------- 121
+ + DR+ C G + +QC L
Sbjct: 170 RLLHGVGDRSPP----------QCSPDGAFRPVQCKLVNTTDMMIFDLVHSYSRFPDAFV 219
Query: 120 --------------YCYCADANGKKLPSSSTIYITD 55
YCYCAD+ G++L + + D
Sbjct: 220 TFSSFRSRFPEVSGYCYCADSQGRELAETGLELLLD 255
Score = 41.2 bits (95), Expect = 0.001
Identities = 19/64 (29%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Frame = -2
Query: 366 VILPSCEENGDYKPVQCGESSCYCSDENGKEIYGFDTSI--ELRTYKNCNCAVDRAKNSG 193
+ +P+C G++ PVQC S CYC D G+ I G +++ + C +RA
Sbjct: 681 LFVPACTSKGNFLPVQCFNSECYCVDTEGQPIPGTRSALGEPKKCPSPCQLQAERAFLGT 740
Query: 192 IKTI 181
++T+
Sbjct: 741 VRTL 744
Score = 35.8 bits (81), Expect = 0.050
Identities = 14/33 (42%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
Frame = -2
Query: 360 LPSCEENGDYKPVQCGESS-CYCSDENGKEIYG 265
+PSC +G+Y+ QC + C+C D G+EI G
Sbjct: 316 VPSCHPDGEYQAAQCQQGGPCWCVDSRGQEIPG 348
Score = 35.8 bits (81), Expect = 0.050
Identities = 29/112 (25%), Positives = 54/112 (48%), Gaps = 19/112 (16%)
Frame = -2
Query: 360 LPSCEENGDYKPVQCGESS--CYCSDENGKEIYGFDTSIELRTYK--NCNCAVDRAKNSG 193
LP C+ G ++PVQC ++ C+C D G+ + TS+ R+ + C + +R + SG
Sbjct: 1028 LPQCDAFGGWEPVQCHAATGHCWCVDGKGEYV---PTSLTARSRQIPQCPTSCERLRASG 1084
Query: 192 IKT------IQLSFN--------CDKLGNYEKLQCPLFYCYCAD-ANGKKLP 82
+ + +Q + C + G + +LQ +C D A+G+ +P
Sbjct: 1085 LLSSWKQAGVQAEPSPKDLFIPTCLETGEFARLQASEAGTWCVDPASGEGVP 1136
Score = 32.3 bits (72), Expect = 0.56
Identities = 13/34 (38%), Positives = 20/34 (58%), Gaps = 2/34 (5%)
Frame = -2
Query: 165 CDKLGNYEKLQCPLF--YCYCADANGKKLPSSST 70
CD G +E +QC +C+C D G+ +P+S T
Sbjct: 1031 CDAFGGWEPVQCHAATGHCWCVDGKGEYVPTSLT 1064
Score = 30.4 bits (67), Expect = 2.1
Identities = 22/106 (20%), Positives = 45/106 (42%), Gaps = 8/106 (7%)
Frame = -2
Query: 369 DVILPSCEENGDYKPVQCGESSCYCSDENGKEIYGFDTSIELRTYKNCNC-AVDRAKNSG 193
D+ +P+C E G++ +Q E+ +C D E + T + C ++ SG
Sbjct: 1102 DLFIPTCLETGEFARLQASEAGTWCVDPASGE------GVPPGTNSSAQCPSLCEVLQSG 1155
Query: 192 IKTIQLSFNCDKL-----GNYEKLQCPLFY--CYCADANGKKLPSS 76
+ + + S G + +QC C+C +G+++P +
Sbjct: 1156 VPSRRTSPGYSPACRAEDGGFSPVQCDPAQGSCWCVLGSGEEVPGT 1201
>sp|P01266|THYG_HUMAN Thyroglobulin precursor
Length = 2768
Score = 50.8 bits (120), Expect = 2e-06
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 8/105 (7%)
Frame = -2
Query: 366 VILPSCEENGDYKPVQCGESSCYCSDENGKEIYGFDTSIELRTYKNC--NCAVDRAKNSG 193
+ +PSC G Y+ VQC C+C + GKE+ G S C +C RA+
Sbjct: 615 LFVPSCTTEGSYEDVQCFSGECWCVNSWGKELPG---SRVRGGQPRCPTDCEKQRARMQS 671
Query: 192 IKTIQLSFN------CDKLGNYEKLQCPLFYCYCADANGKKLPSS 76
+ Q + + C G++ +QC CYC DA G+ +P +
Sbjct: 672 LMGSQPAGSTLFVPACTSEGHFLPVQCFNSECYCVDAEGQAIPGT 716
Score = 45.4 bits (106), Expect = 6e-05
Identities = 32/123 (26%), Positives = 52/123 (42%), Gaps = 8/123 (6%)
Frame = -2
Query: 360 LPSCEENGDYKPVQCGES--SCYCSDENGKEIYGF-DTSIELRTYKNCNCAVDRAKNSG- 193
+P C E+G ++ VQC SC+C NG E+ G + C + SG
Sbjct: 49 VPQCAEDGSFQTVQCQNDGRSCWCVGANGSEVLGSRQPGRPVACLSFCQLQKQQILLSGY 108
Query: 192 IKTIQLSF--NCDKLGNYEKLQCPL--FYCYCADANGKKLPSSSTIYITDRNKLKCD*IN 25
I + S+ C G+Y +QC + C+C DA G ++ + + R C+ N
Sbjct: 109 INSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTRQLGRPKRCPRSCEIRN 168
Query: 24 NEI 16
+
Sbjct: 169 RRL 171
Score = 43.9 bits (102), Expect = 2e-04
Identities = 18/33 (54%), Positives = 23/33 (69%), Gaps = 1/33 (3%)
Frame = -2
Query: 360 LPSCEENGDYKPVQC-GESSCYCSDENGKEIYG 265
+PSC NGDY+ VQC E C+C D GKE++G
Sbjct: 316 VPSCRRNGDYQAVQCQTEGPCWCVDAQGKEMHG 348
Score = 43.9 bits (102), Expect = 2e-04
Identities = 35/115 (30%), Positives = 55/115 (47%), Gaps = 18/115 (15%)
Frame = -2
Query: 360 LPSCEENGDYKPVQC--GESSCYCSDENGKEIYGFDTSIELRTYKNCNCAVDRAKNSGI- 190
+P C+ G ++PVQC G C+C DE G I G T+ L+ C ++++ SG+
Sbjct: 1028 MPQCDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGSLTARSLQ-IPQCPTTCEKSRTSGLL 1086
Query: 189 ---KTIQLSFN----------CDKLGNYEKLQCPLFYCYCAD-ANGKKL-PSSST 70
K + N C + G Y +LQ +C D A+G++L P SS+
Sbjct: 1087 SSWKQARSQENPSPKDLFVPACLETGEYARLQASGAGTWCVDPASGEELRPGSSS 1141
Score = 40.4 bits (93), Expect = 0.002
Identities = 16/39 (41%), Positives = 23/39 (58%)
Frame = -2
Query: 366 VILPSCEENGDYKPVQCGESSCYCSDENGKEIYGFDTSI 250
+ +P+C G + PVQC S CYC D G+ I G ++I
Sbjct: 682 LFVPACTSEGHFLPVQCFNSECYCVDAEGQAIPGTRSAI 720
Score = 32.7 bits (73), Expect = 0.43
Identities = 26/130 (20%), Positives = 47/130 (36%), Gaps = 2/130 (1%)
Frame = -2
Query: 459 CDVVCKEDSNAPTCFKKHLNARRITKNGALDVILPSCEENGDYKPVQCGESSCYCSDENG 280
C C E S AR D+ +P+C E G+Y +Q + +C D
Sbjct: 1073 CPTTC-EKSRTSGLLSSWKQARSQENPSPKDLFVPACLETGEYARLQASGAGTWCVDPAS 1131
Query: 279 KEIYGFDTSIELRTYKNCNCAVDRAKNSGIKTIQLSFNCDKLGNYEKLQCPLFY--CYCA 106
E +S + CN + + + + G + +QC C+C
Sbjct: 1132 GEELRPGSSSSAQCPSLCNVLKSGVLSRRVSPGYVPACRAEDGGFSPVQCDQAQGSCWCV 1191
Query: 105 DANGKKLPSS 76
+G+++P +
Sbjct: 1192 MDSGEEVPGT 1201
>sp|O88322|NID2_MOUSE Nidogen-2 precursor (NID-2) (Entactin-2)
Length = 1403
Score = 46.6 bits (109), Expect = 3e-05
Identities = 32/113 (28%), Positives = 53/113 (46%), Gaps = 21/113 (18%)
Frame = -2
Query: 360 LPSCEENGDYKPVQCGESS--CYCSDENGKEIYGFDTSIELRTYKNC----------NCA 217
+P C++ G++ P+QC S+ C+C D NG E+ G T T +C
Sbjct: 988 IPQCDDQGNFVPLQCHGSTGFCWCVDRNGHEVPGTQTP-PGSTPPHCGPPPEPTQRPRTV 1046
Query: 216 VDRAKNSGI-------KTIQLSFNCDKLGNYEKLQC--PLFYCYCADANGKKL 85
+R + S + + Q CD LG++ LQC +C+C D +G++L
Sbjct: 1047 CERWRESLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREL 1099
Score = 35.8 bits (81), Expect = 0.050
Identities = 14/37 (37%), Positives = 24/37 (64%), Gaps = 2/37 (5%)
Frame = -2
Query: 369 DVILPSCEENGDYKPVQCGESS--CYCSDENGKEIYG 265
D +P C++ G + P+QC S C+C D++G+E+ G
Sbjct: 1065 DQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGRELQG 1101
Score = 34.7 bits (78), Expect = 0.11
Identities = 14/34 (41%), Positives = 20/34 (58%), Gaps = 2/34 (5%)
Frame = -2
Query: 165 CDKLGNYEKLQC--PLFYCYCADANGKKLPSSST 70
CD GN+ LQC +C+C D NG ++P + T
Sbjct: 991 CDDQGNFVPLQCHGSTGFCWCVDRNGHEVPGTQT 1024
>sp|P31226|SAX_RANCA Saxiphilin precursor (SAX)
Length = 844
Score = 44.3 bits (103), Expect = 1e-04
Identities = 31/109 (28%), Positives = 51/109 (46%), Gaps = 12/109 (11%)
Frame = -2
Query: 360 LPSCEENGDYKPVQCGESS--CYCSDENGKEIYGFDT-------SIELRTYKNCNCAVDR 208
+P C+E G+Y+P QC S+ C+C + G++I G +T + E C
Sbjct: 127 IPQCDEKGNYQPQQCHGSTGHCWCVNAMGEKISGTNTPPGQTRATCERHELPKCLKERQV 186
Query: 207 AKNSGIKTI-QLSFNCDKLGNYEKLQC--PLFYCYCADANGKKLPSSST 70
A K + + CD+ GNYE Q Y +C +A G+++ + T
Sbjct: 187 ALGGDEKVLGRFVPQCDEKGNYEPQQFHGSTGYSWCVNAIGEEIAGTKT 235
>sp|Q14112|NID2_HUMAN Nidogen-2 precursor (NID-2) (Osteonidogen)
Length = 1375
Score = 43.5 bits (101), Expect = 2e-04
Identities = 29/113 (25%), Positives = 51/113 (45%), Gaps = 21/113 (18%)
Frame = -2
Query: 360 LPSCEENGDYKPVQCGESS--CYCSDENGKEIYGFDTSIELRTYKNCNCAVDRAKNSGI- 190
+P C+E G++ P+QC S+ C+C D +G E+ G T T +C + + +
Sbjct: 960 IPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTP-PGSTPPHCGPSPEPTQRPPTI 1018
Query: 189 ----------------KTIQLSFNCDKLGNYEKLQC--PLFYCYCADANGKKL 85
+ Q CD LG++ LQC +C+C D +G+++
Sbjct: 1019 CERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREV 1071
Score = 36.2 bits (82), Expect = 0.039
Identities = 14/37 (37%), Positives = 24/37 (64%), Gaps = 2/37 (5%)
Frame = -2
Query: 369 DVILPSCEENGDYKPVQCGESS--CYCSDENGKEIYG 265
D +P C++ G + P+QC S C+C D++G+E+ G
Sbjct: 1037 DQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQG 1073
Score = 33.1 bits (74), Expect = 0.33
Identities = 13/34 (38%), Positives = 21/34 (61%), Gaps = 2/34 (5%)
Frame = -2
Query: 165 CDKLGNYEKLQC--PLFYCYCADANGKKLPSSST 70
CD+ GN+ LQC +C+C D +G ++P + T
Sbjct: 963 CDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQT 996
>sp|Q92563|TICN2_HUMAN Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like
domains proteoglycan 2)
Length = 424
Score = 40.8 bits (94), Expect = 0.002
Identities = 17/39 (43%), Positives = 27/39 (69%), Gaps = 2/39 (5%)
Frame = -2
Query: 366 VILPSCEENGDYKPVQCGESS--CYCSDENGKEIYGFDT 256
+ +PSC+E+G Y+ +QC +SS C+C D+ G E+ G T
Sbjct: 332 IFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRT 370
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,802,445
Number of Sequences: 369166
Number of extensions: 879962
Number of successful extensions: 2499
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2285
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2439
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2733320975
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)