Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_E03
(840 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9JIX8|ACINU_MOUSE Apoptotic chromatin condensation indu... 92 2e-18
sp|Q9UKV3|ACINU_HUMAN Apoptotic chromatin condensation indu... 91 4e-18
sp|O94312|YH57_SCHPO PWWP domain protein C215.07c 37 0.052
sp|O01761|UNC89_CAEEL Muscle M-line assembly protein unc-89... 37 0.052
sp|Q8JFV8|VAT1_BRARE Synaptic vesicle membrane protein VAT-... 36 0.12
sp|O96433|CCNT_DROME Cyclin-T 36 0.12
sp|P42872|TONB_HAEIN Protein tonB 36 0.15
sp|Q28820|TRDN_RABIT Triadin 36 0.15
sp|O97758|ZO1_CANFA Tight junction protein ZO-1 (Zonula occ... 36 0.15
sp|Q00194|CNGA1_BOVIN cGMP-gated cation channel alpha 1 (CN... 36 0.15
>sp|Q9JIX8|ACINU_MOUSE Apoptotic chromatin condensation inducer in the nucleus (Acinus)
Length = 1338
Score = 91.7 bits (226), Expect = 2e-18
Identities = 59/210 (28%), Positives = 99/210 (47%), Gaps = 23/210 (10%)
Frame = +2
Query: 266 IEGPERV-EPAQKPKNSISEVLRIDNLVRPFTLVQLQDMLALQGSVKE--IWLNKIKSVA 436
I+ P R + P+ IS ++ I NLVRPFTL QL+++L G++ E W++KIKS
Sbjct: 992 IDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHC 1051
Query: 437 YVRYENETTADSARETIDGCRWPSINPKLLSCDFVCSKEMEWMK----------ENGDSG 586
+V Y A + R + G +WP NPK L D+ E+++ + + + G
Sbjct: 1052 FVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHRGLLVDRPSETKAEEQG 1111
Query: 587 A------PPPSNFRQLPQPEQKESIKQNTHKEQGPSQ----EQNKPANVDNEWKPVDKPK 736
A PPP + P P ++ ++ +EQ + E+ + + EW DK +
Sbjct: 1112 APRPLHPPPPPPVQPPPHPRAEQREQERAVREQWAEREREMERRERTRSEREWDR-DKVR 1170
Query: 737 TSNREHQQPSTHHKSDKATDDSKKRERKER 826
R + + ++A KK E+KE+
Sbjct: 1171 EGPRSRSRSRDRRRKERAKSKEKKSEKKEK 1200
>sp|Q9UKV3|ACINU_HUMAN Apoptotic chromatin condensation inducer in the nucleus (Acinus)
Length = 1341
Score = 90.9 bits (224), Expect = 4e-18
Identities = 61/210 (29%), Positives = 97/210 (46%), Gaps = 23/210 (10%)
Frame = +2
Query: 266 IEGPERV-EPAQKPKNSISEVLRIDNLVRPFTLVQLQDMLALQGSVKE--IWLNKIKSVA 436
I+ P R + P+ IS ++ I NLVRPFTL QL+++L G++ E W++KIKS
Sbjct: 993 IDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHC 1052
Query: 437 YVRYENETTADSARETIDGCRWPSINPKLLSCDFVCSKEMEW-------------MKENG 577
+V Y A + R + G +WP NPK L D+ E+++ +E G
Sbjct: 1053 FVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHRGLLVDRPSETKTEEQG 1112
Query: 578 -----DSGAPPPSNFRQLPQPEQKESIK--QNTHKEQGPSQEQNKPANVDNEWKPVDKPK 736
PPP Q P+ EQ+E + + E+ E+ + + EW DK +
Sbjct: 1113 IPRPLHPPPPPPVQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDR-DKVR 1171
Query: 737 TSNREHQQPSTHHKSDKATDDSKKRERKER 826
R + + ++A KK E+KE+
Sbjct: 1172 EGPRSRSRSRDRRRKERAKSKEKKSEKKEK 1201
>sp|O94312|YH57_SCHPO PWWP domain protein C215.07c
Length = 568
Score = 37.4 bits (85), Expect = 0.052
Identities = 48/183 (26%), Positives = 67/183 (36%), Gaps = 16/183 (8%)
Frame = +2
Query: 302 PKNSISEV--LRIDNLVRPFTLVQLQDMLALQGSVKEIWLNKIKSVAYVRYENETTADSA 475
PK +S+V + N + Q D+ +Q + + + KI S+A + ENE S
Sbjct: 364 PKQDLSQVDYKLVHNYLDKLANFQGIDVPLIQKTKIAVVVRKIFSLAGLPKENEDEVKSI 423
Query: 476 RETIDGCRWPSI-----NPKLLSCDFVCSKEMEWMKEN---------GDSGAPPPSNFRQ 613
I RW S+ + K LS D +++ EN G P PS
Sbjct: 424 CGDILENRWKSLLQEISSQKQLSTDASQTQDASIANENETEIASLDEGSESKPTPS---- 479
Query: 614 LPQPEQKESIKQNTHKEQGPSQEQNKPANVDNEWKPVDKPKTSNREHQQPSTHHKSDKAT 793
P EQ KQN E + N P +NE K S KS K
Sbjct: 480 -PPAEQLTDQKQNEDNEDKVKADSNGPTQNENETADASKDMIS---------EEKSSKDA 529
Query: 794 DDS 802
D+S
Sbjct: 530 DNS 532
>sp|O01761|UNC89_CAEEL Muscle M-line assembly protein unc-89 (Uncoordinated protein 89)
Length = 8081
Score = 37.4 bits (85), Expect = 0.052
Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 4/98 (4%)
Frame = +2
Query: 545 SKEMEWMKENGDSGAPPPSNFRQLPQPEQKESIKQNTHKEQGPSQEQNKPANVDNEWKPV 724
S + E E D P+ + P+ E IK KE+ P + + KPA+ + K
Sbjct: 1525 SVKKEKTPEKVDEKPKSPTKKDKSPEKSITEEIKSPVKKEKSPEKVEEKPASPTKKEKSP 1584
Query: 725 DKP----KTSNREHQQPSTHHKSDKATDDSKKRERKER 826
+KP K S E + P+ KS + + + + KE+
Sbjct: 1585 EKPASPTKKSENEVKSPTKKEKSPEKSVVEELKSPKEK 1622
Score = 30.0 bits (66), Expect = 8.3
Identities = 27/110 (24%), Positives = 43/110 (39%), Gaps = 22/110 (20%)
Frame = +2
Query: 566 KENGDS---GAPPPSNFRQLPQPEQKESIKQNTHKEQGP---------------SQEQNK 691
K+ GD +PP S ++ PE+ E +K KE+ P E
Sbjct: 1452 KKTGDEVKEKSPPKSPTKKEKSPEKPEDVKSPVKKEKSPDATNIVEVSSETTIEKTETTM 1511
Query: 692 PANVDNEWK----PVDKPKTSNREHQQPSTHHKSDKATDDSKKRERKERV 829
+ +E + V K KT + ++P + K DK+ + S E K V
Sbjct: 1512 TTEMTHESEESRTSVKKEKTPEKVDEKPKSPTKKDKSPEKSITEEIKSPV 1561
>sp|Q8JFV8|VAT1_BRARE Synaptic vesicle membrane protein VAT-1 homolog
Length = 484
Score = 36.2 bits (82), Expect = 0.12
Identities = 17/70 (24%), Positives = 33/70 (47%)
Frame = +2
Query: 620 QPEQKESIKQNTHKEQGPSQEQNKPANVDNEWKPVDKPKTSNREHQQPSTHHKSDKATDD 799
+P ++E K+ K++ ++ K ++ K DK K ++ ++ K + DD
Sbjct: 410 EPMKEEEKKEEAKKDEEKKDDKKKDDKKKDDKKKEDKKKDEAKKEEKKDEKKKEEAKKDD 469
Query: 800 SKKRERKERV 829
K E+KE V
Sbjct: 470 KKAEEKKEEV 479
>sp|O96433|CCNT_DROME Cyclin-T
Length = 1097
Score = 36.2 bits (82), Expect = 0.12
Identities = 31/127 (24%), Positives = 51/127 (40%), Gaps = 4/127 (3%)
Frame = +2
Query: 455 ETTADSARETIDGCRWPSINPKLLSCDFVCSKEMEWMKENGDSGAPPPSNFRQLPQP--- 625
ETT D R + PS N LL D + ++ PP +P P
Sbjct: 783 ETTPDLVRSLLKESLCPS-NASLLKPDALTMPGLK----------PPAELLEPMPAPATI 831
Query: 626 EQKESIKQNTHKEQGPS-QEQNKPANVDNEWKPVDKPKTSNREHQQPSTHHKSDKATDDS 802
++++ I T GP+ + P E K K+ ++ + H + DK+ D +
Sbjct: 832 KKEQGITPMTSLASGPAPMDLEVPTKQAGEIKEESSSKSEKKKKKDKHKHKEKDKSKDKT 891
Query: 803 KKRERKE 823
+K ERK+
Sbjct: 892 EKEERKK 898
>sp|P42872|TONB_HAEIN Protein tonB
Length = 270
Score = 35.8 bits (81), Expect = 0.15
Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 7/78 (8%)
Frame = +2
Query: 590 PPPSNFRQLPQPEQKE-----SIKQNTHKEQGPSQEQNKPANVDNEWKPVDKPKTSNREH 754
P P N ++ P+PE++E +IK K + P +E+ KP + KP +KPK +
Sbjct: 75 PEPGNVQKEPEPEKQEIVEDPTIKPEPKKIKEPEKEKPKPKG-KPKGKPKNKPKKEVKPQ 133
Query: 755 QQPSTHH--KSDKATDDS 802
++P K D+ D S
Sbjct: 134 KKPINKELPKGDENIDSS 151
>sp|Q28820|TRDN_RABIT Triadin
Length = 706
Score = 35.8 bits (81), Expect = 0.15
Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 1/89 (1%)
Frame = +2
Query: 566 KENGDSGAPPPSNFRQLPQPE-QKESIKQNTHKEQGPSQEQNKPANVDNEWKPVDKPKTS 742
KE G S P + Q +K+ K+++ K + P++EQ K + + K + K++
Sbjct: 351 KEPGKSPDTKPGTVKVTTQAATKKDEKKEDSKKAKKPAEEQPKGKKQEKKEKHEEPAKST 410
Query: 743 NREHQQPSTHHKSDKATDDSKKRERKERV 829
+EH PS K KA K ERKE V
Sbjct: 411 KKEHAAPS--EKQAKA-----KIERKEEV 432
Score = 30.4 bits (67), Expect = 6.4
Identities = 29/114 (25%), Positives = 44/114 (38%), Gaps = 23/114 (20%)
Frame = +2
Query: 563 MKENGDSGAPPPSNFRQ-------LPQPEQKESIKQNTHK-----------EQGPSQEQN 688
+K PPPS Q LP PE+KE K+ K ++ ++
Sbjct: 282 LKPGQSPAIPPPSPTEQASRPTPALPTPEEKEGEKKKAEKKVTTETKKKAEKEDAKKKSE 341
Query: 689 KPANVDNEWK-----PVDKPKTSNREHQQPSTHHKSDKATDDSKKRERKERVVP 835
K ++D + K P KP T Q + K D+ +DSKK ++ P
Sbjct: 342 KETDIDMKKKEPGKSPDTKPGTVKVTTQAAT---KKDEKKEDSKKAKKPAEEQP 392
>sp|O97758|ZO1_CANFA Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona
occludens 1 protein) (Tight junction protein 1)
Length = 1769
Score = 35.8 bits (81), Expect = 0.15
Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Frame = +2
Query: 581 SGAPPPSNFRQLPQPEQKESIKQNTHKEQG----PSQEQNKPANVDNEWKPVDKPKTSNR 748
S P +R+ P PE E ++QN +Q P Q +K N+ E +P K +NR
Sbjct: 994 SHVEPAKVYRKDPYPE--EMMRQNHVLKQPAVGHPGQRPDKEPNLSYESQPPYVEKQANR 1051
Query: 749 EHQQPSTHHKSDKATDDSKK----RERKERVVPS 838
+ +QP+ + S TD + R R E +P+
Sbjct: 1052 DLEQPTYRYDSSSYTDQFSRNYDHRLRYEERIPT 1085
>sp|Q00194|CNGA1_BOVIN cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1)
(CNG1) (Cyclic nucleotide gated channel alpha 1) (Cyclic
nucleotide gated channel, photoreceptor)
(Cyclic-nucleotide-gated cation channel 1) (Rod
photoreceptor cGMP-gated channel alpha subunit)
Length = 690
Score = 35.8 bits (81), Expect = 0.15
Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 10/75 (13%)
Frame = +2
Query: 623 PEQKESIKQNTHKEQGPSQ-EQNKPA-----NVDN----EWKPVDKPKTSNREHQQPSTH 772
P ++S + NTH PSQ EQ P NV+N E +P +K K + +P
Sbjct: 57 PHARDSFRSNTHGSGQPSQREQYLPGAIALFNVNNSSNKEQEPKEKKKKKKEKKSKPDDK 116
Query: 773 HKSDKATDDSKKRER 817
+++ K + KK+E+
Sbjct: 117 NENKKDPEKKKKKEK 131
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,853,872
Number of Sequences: 369166
Number of extensions: 1620776
Number of successful extensions: 7142
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6418
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7056
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8197207050
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)