Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_019_D10 (968 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-intera... 114 4e-25 sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-intera... 112 1e-24 sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interact... 109 1e-23 sp|Q8TC41|IBR1_HUMAN IBR domain containing protein 1 45 3e-04 sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52... 42 0.002 sp|O76924|ARI2_DROME Ariadne-2 protein (Ari-2) 42 0.003 sp|P50876|UB7I4_HUMAN Ubiquitin-conjugating enzyme 7-intera... 42 0.003 sp|Q925F3|UB7I4_MOUSE Ubiquitin-conjugating enzyme 7-intera... 41 0.006 sp|Q04638|YMG8_YEAST Hypothetical 54.1 kDa protein in DAK1-... 40 0.008 sp|Q9NWF9|UB7I1_HUMAN E3 ubiquitin ligase TRIAD3 (Ubiquitin... 39 0.017
>sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-interacting protein 3 (Hepatitis B virus X-associated protein 4) (HBV-associated factor 4) (RING finger protein 54) Length = 500 Score = 114 bits (285), Expect = 4e-25 Identities = 50/141 (35%), Positives = 75/141 (53%), Gaps = 8/141 (5%) Frame = +1 Query: 79 FQCQTPNCDAFYEISESLKEFTXXXXXXXXXXXXXTVHLNENCEQFKK----RMETDVNM 246 + C+TP+C + + + EFT +H NC+++++ R + DV Sbjct: 359 YHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAA 418 Query: 247 KAIEEKIK----NKELMKCPKCSNYIVRSTGCYGIKCSNCSTELCWIRQMERWGPGGYGD 414 + E +K E M+CP+C + + GC I+C+ C TE+CW+ + RWGPGG GD Sbjct: 419 RQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGD 478 Query: 415 TSGGCRCEVDRKKCHPDCIGC 477 TSGGCRC V+ CHP C C Sbjct: 479 TSGGCRCRVNGIPCHPSCQNC 499
>sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-interacting protein 3 (UbcM4-interacting protein 28) Length = 498 Score = 112 bits (281), Expect = 1e-24 Identities = 55/168 (32%), Positives = 83/168 (49%), Gaps = 9/168 (5%) Frame = +1 Query: 1 RAILSDNQFSIY-QVKCQDFSKKSIPHFQCQTPNCDAFYEISESLKEFTXXXXXXXXXXX 177 RA+LS + + + +S + C+TP+C + + + EFT Sbjct: 330 RALLSPEDYQRFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDVNEFTCPVCTRVNCLL 389 Query: 178 XXTVHLNENCEQFKK----RMETDVNMKAIEEKIK----NKELMKCPKCSNYIVRSTGCY 333 +H + NC +++ R + DV + E +K E M CP+C + + GC Sbjct: 390 CKAIHEHMNCREYQDDLALRAQNDVAARQTTEMLKVMLQQGEAMHCPQCRIVVQKKDGCD 449 Query: 334 GIKCSNCSTELCWIRQMERWGPGGYGDTSGGCRCEVDRKKCHPDCIGC 477 I+C+ C TE+CW+ + RWGPGG GDTSGGCRC V+ CHP C C Sbjct: 450 WIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQNC 497
>sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interacting protein 3 (RBCC protein interacting with PKC) (Protein kinase C-binding protein beta-15) Length = 498 Score = 109 bits (273), Expect = 1e-23 Identities = 54/168 (32%), Positives = 81/168 (48%), Gaps = 9/168 (5%) Frame = +1 Query: 1 RAILSDNQFSIY-QVKCQDFSKKSIPHFQCQTPNCDAFYEISESLKEFTXXXXXXXXXXX 177 RA+LS + + + +S + C+TP+C + + + EFT Sbjct: 330 RALLSPEDYQRFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDVNEFTCPVCTRVNCLL 389 Query: 178 XXTVHLNENCEQFKK----RMETDVNMKAIEEKIK----NKELMKCPKCSNYIVRSTGCY 333 +H NC +++ R DV + E ++ E M CP+C + + GC Sbjct: 390 CKAIHERMNCREYQDDLAHRARNDVAAQQTTEMLRVMLQQGEAMYCPQCRIVVQKKDGCD 449 Query: 334 GIKCSNCSTELCWIRQMERWGPGGYGDTSGGCRCEVDRKKCHPDCIGC 477 I+C+ C TE+CW+ + RWGPGG GDTSGGCRC V+ CHP C C Sbjct: 450 WIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQNC 497
>sp|Q8TC41|IBR1_HUMAN IBR domain containing protein 1 Length = 275 Score = 45.1 bits (105), Expect = 3e-04 Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 5/86 (5%) Frame = +1 Query: 190 HLNENCEQFKKRMETDVNMKAIEEKIKNKELMKCPKCSNYIVRSTGCYGIKCSNCSTELC 369 H NC+++KK + + A E + + KCPKC +I R+ GC + CS C+T C Sbjct: 99 HEGVNCKEYKKGDKL-LRHWASEIEHGQRNAQKCPKCKIHIQRTEGCDHMTCSQCNTNFC 157 Query: 370 W-----IRQMERWGPGGYGDTSGGCR 432 + RQ+ +G + GC+ Sbjct: 158 YRCGERYRQLRFFGDHTSNLSIFGCK 183
>sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52-GCN3 intergenic region Length = 551 Score = 42.4 bits (98), Expect = 0.002 Identities = 18/40 (45%), Positives = 24/40 (60%) Frame = +1 Query: 286 KCPKCSNYIVRSTGCYGIKCSNCSTELCWIRQMERWGPGG 405 +CPKCS I ++ GC + CS+C E CWI + W P G Sbjct: 340 ECPKCSVNIEKNGGCNHMVCSSCKYEFCWICE-GPWAPHG 378
>sp|O76924|ARI2_DROME Ariadne-2 protein (Ari-2) Length = 509 Score = 41.6 bits (96), Expect = 0.003 Identities = 36/147 (24%), Positives = 54/147 (36%), Gaps = 3/147 (2%) Frame = +1 Query: 64 KSIPHFQ-CQTPNCDAFYEISE--SLKEFTXXXXXXXXXXXXXTVHLNENCEQFKKRMET 234 KS P + C PNC + SE + + H +C+ KK + Sbjct: 234 KSHPELRFCPGPNCQIIVQSSEISAKRAICKACHTGFCFRCGMDYHAPTDCQVIKKWLTK 293 Query: 235 DVNMKAIEEKIKNKELMKCPKCSNYIVRSTGCYGIKCSNCSTELCWIRQMERWGPGGYGD 414 + I + CPKC I ++ GC ++C NC + CW+ G Sbjct: 294 CADDSETANYI-SAHTKDCPKCHICIEKNGGCNHMQCFNCKHDFCWMCL-------GDWK 345 Query: 415 TSGGCRCEVDRKKCHPDCIGCTVHNNA 495 T G E R K +P+ +VH A Sbjct: 346 THGSEYYECSRYKDNPNIANESVHVQA 372
>sp|P50876|UB7I4_HUMAN Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4-interacting protein 4) (RING finger protein 144) Length = 292 Score = 41.6 bits (96), Expect = 0.003 Identities = 18/48 (37%), Positives = 23/48 (47%) Frame = +1 Query: 229 ETDVNMKAIEEKIKNKELMKCPKCSNYIVRSTGCYGIKCSNCSTELCW 372 ET K E+ + + +CPKC YI R GC + C NC CW Sbjct: 168 ETSAAFKMEED---DAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCW 212
>sp|Q925F3|UB7I4_MOUSE Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4-interacting protein 4) (RING finger protein 144) Length = 292 Score = 40.8 bits (94), Expect = 0.006 Identities = 14/31 (45%), Positives = 17/31 (54%) Frame = +1 Query: 280 LMKCPKCSNYIVRSTGCYGIKCSNCSTELCW 372 + +CPKC YI R GC + C NC CW Sbjct: 182 IKRCPKCRVYIERDEGCAQMMCKNCKHAFCW 212
>sp|Q04638|YMG8_YEAST Hypothetical 54.1 kDa protein in DAK1-ORC1 intergenic region Length = 464 Score = 40.4 bits (93), Expect = 0.008 Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 6/59 (10%) Frame = +1 Query: 217 KKRMETDVNMKAIEE------KIKNKELMKCPKCSNYIVRSTGCYGIKCSNCSTELCWI 375 ++ +E +VN E+ K + L +CPKC + RS GC +KC C T C+I Sbjct: 372 RRVLELEVNDYLAEKMLDLAIKKEGSNLQRCPKCKVVVERSEGCNKMKCEVCGTLFCFI 430
>sp|Q9NWF9|UB7I1_HUMAN E3 ubiquitin ligase TRIAD3 (Ubiquitin conjugating enzyme 7 interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) Length = 866 Score = 39.3 bits (90), Expect = 0.017 Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 1/63 (1%) Frame = +1 Query: 190 HLNENCEQFKKRMETDVNMK-AIEEKIKNKELMKCPKCSNYIVRSTGCYGIKCSNCSTEL 366 H CE+ ++ D+ + +IEEK+ + KC KC +++S GC + C C ++ Sbjct: 643 HNGLTCEELAEK--DDIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSC-RCGAQM 699 Query: 367 CWI 375 C++ Sbjct: 700 CYL 702
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 90,647,764 Number of Sequences: 369166 Number of extensions: 1652848 Number of successful extensions: 4852 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4655 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4838 length of database: 68,354,980 effective HSP length: 111 effective length of database: 47,849,395 effective search space used: 10096222345 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)