Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_B08
(926 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P04275|VWF_HUMAN Von Willebrand factor precursor (vWF) [... 80 8e-15
sp|Q8CIZ8|VWF_MOUSE Von Willebrand factor precursor (vWF) [... 77 9e-14
sp|P80012|VWF_BOVIN Von Willebrand factor precursor (vWF) 76 1e-13
sp|Q28295|VWF_CANFA Von Willebrand factor precursor (vWF) 71 4e-12
sp|Q02817|MUC2_HUMAN Mucin-2 precursor (Intestinal mucin 2) 70 6e-12
sp|Q9HC84|MUC5B_HUMAN Mucin-5B precursor (Mucin 5 subtype B... 65 3e-10
sp|Q28833|VWF_PIG Von Willebrand factor precursor (vWF) 64 5e-10
sp|O88799|ZAN_MOUSE Zonadhesin precursor 63 1e-09
sp|Q62635|MUC2_RAT Mucin-2 precursor (Intestinal mucin 2) 61 5e-09
sp|P98167|SSPO_BOVIN SCO-spondin 54 8e-07
>sp|P04275|VWF_HUMAN Von Willebrand factor precursor (vWF) [Contains: Von Willebrand
antigen II]
Length = 2813
Score = 80.1 bits (196), Expect = 8e-15
Identities = 41/144 (28%), Positives = 64/144 (44%), Gaps = 2/144 (1%)
Frame = +2
Query: 95 CGNGMVTKTPQEVIKAVNGGKDCDVIYEPCFLGNCSTACVAPKKLLSCVNPCEIRCGDL- 271
C G+ P + A ++ V+Y CS C A + CV+PC C L
Sbjct: 257 CAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLH 316
Query: 272 -SKKCSNVDCIESCACPDNMLEQDGTCVQKTDCRCTWNADLLGPKPIGYNEESLPDTIFT 448
++ C C++ C+CP+ L +G CV+ T+C C + + P T +
Sbjct: 317 INEMCQE-RCVDGCSCPEGQLLDEGLCVESTECPCVHSG-----------KRYPPGTSLS 364
Query: 449 KDCNNCSCRQGKWICTKNICTKDC 520
+DCN C CR +WIC+ C +C
Sbjct: 365 RDCNTCICRNSQWICSNEECPGEC 388
Score = 64.7 bits (156), Expect = 4e-10
Identities = 59/249 (23%), Positives = 90/249 (36%), Gaps = 4/249 (1%)
Frame = +2
Query: 191 GNCSTACVAPKKLLSCVNPCEIRCGDLS---KKCSNVDCIESCACPDNM-LEQDGTCVQK 358
G C C + L C PC + C LS ++C N C+E C CP + +++ G CV K
Sbjct: 646 GRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEEC-NEACLEGCFCPPGLYMDERGDCVPK 704
Query: 359 TDCRCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGKWICTKNICTKDCQWSDWK 538
C C ++ ++ P+ IF+ C C G CT + D
Sbjct: 705 AQCPCYYDGEIF-----------QPEDIFSDHHTMCYCEDGFMHCTMS-GVPGSLLPDAV 752
Query: 539 ISTPCNVTCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENNVAFSLKNSF 718
+S+P + + + V V + +G TK C+N
Sbjct: 753 LSSPLSHRSKRSLSCRPPMVKLVCPADNLRAEG--------LECTKTCQN---------- 794
Query: 719 CEQTCDDVINKQHPTHICDEGCKCQSGYVRNSNNTCVPTSECFRCEVNGVTWQNGQTKKD 898
+ + + C GC C G VR+ N CV C C G + G+T K
Sbjct: 795 --------YDLECMSMGCVSGCLCPPGMVRHENR-CVALERC-PCFHQGKEYAPGETVK- 843
Query: 899 VYACRLFIC 925
C +C
Sbjct: 844 -IGCNTCVC 851
Score = 58.5 bits (140), Expect = 3e-08
Identities = 45/216 (20%), Positives = 74/216 (34%), Gaps = 45/216 (20%)
Frame = +2
Query: 8 CPVNCKALTYQTSECIKEC-----------------SVNDSQCDPSCGNGMVTKTPQEVI 136
C + C++L+Y EC + C V +QC P +G + + P+++
Sbjct: 665 CNLTCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQC-PCYYDGEIFQ-PEDIF 722
Query: 137 KAVNGGKDCDVIYEPCFLGNCSTACVAP-----------KKLLSCVNP------------ 247
+ C+ + C + + + K+ LSC P
Sbjct: 723 SDHHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLR 782
Query: 248 -----CEIRCGDLSKKCSNVDCIESCACPDNMLEQDGTCVQKTDCRCTWNADLLGPKPIG 412
C C + +C ++ C+ C CP M+ + CV C C
Sbjct: 783 AEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALERCPC-----------FH 831
Query: 413 YNEESLPDTIFTKDCNNCSCRQGKWICTKNICTKDC 520
+E P CN C CR KW CT ++C C
Sbjct: 832 QGKEYAPGETVKIGCNTCVCRDRKWNCTDHVCDATC 867
Score = 37.4 bits (85), Expect = 0.060
Identities = 47/207 (22%), Positives = 79/207 (38%), Gaps = 16/207 (7%)
Frame = +2
Query: 314 CPDNMLEQ---DGTCVQKT-----DCRCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCS 469
C +N+++Q D +C T DC L+ P+P Y + + DT + +C+
Sbjct: 1046 CHNNIMKQTMVDSSCRILTSDVFQDCN-----KLVDPEP--YLDVCIYDTCSCESIGDCA 1098
Query: 470 CRQGKWICTKNICTKDCQWSDWKISTPCNVTCGQGIQILERTVARVAQYEGKDCQGSNRT 649
C ++C + + W+ +T C +C + R + G +C+ +
Sbjct: 1099 CFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEE----------RNLRENGYECEWRYNS 1148
Query: 650 EEMCYAATKCCENNVAFSLKNSFCEQTCDDVINKQHPTHI-----CDEGCK--CQSGYVR 808
C A C+ TC QHP + C EGC C G +
Sbjct: 1149 ---CAPA----------------CQVTC------QHPEPLACPVQCVEGCHAHCPPGKIL 1183
Query: 809 NSN-NTCVPTSECFRCEVNGVTWQNGQ 886
+ TCV +C CEV G + +G+
Sbjct: 1184 DELLQTCVDPEDCPVCEVAGRRFASGK 1210
Score = 34.7 bits (78), Expect = 0.39
Identities = 25/105 (23%), Positives = 42/105 (40%), Gaps = 1/105 (0%)
Frame = +2
Query: 197 CSTACVAPKKLLSCVNPCEIRCGDLSKKCSNVDCIESCACPDNMLEQDGTCVQKTDCRCT 376
C+ +C C + C C C + E C CP + + +G+CV + C
Sbjct: 2199 CAMSCPPSLVYNHCEHGCPRHCDGNVSSCGDHPS-EGCFCPPDKVMLEGSCVPEEACTQC 2257
Query: 377 WNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGKWI-CTKNIC 508
D + + + E +PD + C C+C G+ + CT C
Sbjct: 2258 IGEDGVQHQ---FLEAWVPD---HQPCQICTCLSGRKVNCTTQPC 2296
Score = 30.0 bits (66), Expect = 9.6
Identities = 20/83 (24%), Positives = 35/83 (42%), Gaps = 1/83 (1%)
Frame = +2
Query: 665 AATKCCENNVAFSLKNSFCEQTCDDVINKQHPTHICDEGCKCQSGYVRNSNNTCVPTSEC 844
A + C + + S C +TC + + C +GC C G + + CV ++EC
Sbjct: 290 ACSPVCPAGMEYRQCVSPCARTCQSLHINEMCQERCVDGCSCPEGQLLD-EGLCVESTEC 348
Query: 845 FRCEVNGVTWQNGQT-KKDVYAC 910
C +G + G + +D C
Sbjct: 349 -PCVHSGKRYPPGTSLSRDCNTC 370
Score = 30.0 bits (66), Expect = 9.6
Identities = 16/49 (32%), Positives = 20/49 (40%), Gaps = 4/49 (8%)
Frame = +2
Query: 233 SCVNPCEIRCGDLSKKCSNVDCIESC--ACPDNML--EQDGTCVQKTDC 367
SC C++ C V C+E C CP + E TCV DC
Sbjct: 1148 SCAPACQVTCQHPEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDC 1196
>sp|Q8CIZ8|VWF_MOUSE Von Willebrand factor precursor (vWF) [Contains: Von Willebrand
antigen II]
Length = 2813
Score = 76.6 bits (187), Expect = 9e-14
Identities = 35/109 (32%), Positives = 50/109 (45%), Gaps = 1/109 (0%)
Frame = +2
Query: 197 CSTACVAPKKLLSCVNPCEIRCGDLS-KKCSNVDCIESCACPDNMLEQDGTCVQKTDCRC 373
C AC A + CV+PC C LS + C++ C+CP+ L + CVQ +DC C
Sbjct: 291 CRPACPAGMEYKECVSPCPRTCQSLSINEVCQQQCVDGCSCPEGELLDEDRCVQSSDCPC 350
Query: 374 TWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGKWICTKNICTKDC 520
+ + P T ++DCN C CR WIC+ C +C
Sbjct: 351 -----------VHAGKRYPPGTSLSQDCNTCICRNSLWICSNEECPGEC 388
Score = 68.9 bits (167), Expect = 2e-11
Identities = 62/249 (24%), Positives = 90/249 (36%), Gaps = 4/249 (1%)
Frame = +2
Query: 191 GNCSTACVAPKKLLSCVNPCEIRCGDLS---KKCSNVDCIESCACPDNMLEQD-GTCVQK 358
G C+ C + L C N C + C LS ++CS V C+E C CP + + + G CV K
Sbjct: 646 GFCALGCPQGQVYLQCGNSCNLTCRSLSLPDEECSEV-CLEGCYCPPGLYQDERGDCVPK 704
Query: 359 TDCRCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGKWICTKNICTKDCQWSDWK 538
C C ++ +L P IF+ C C G CT + T D
Sbjct: 705 AQCPCYYDGELFQPA-----------DIFSDHHTMCYCEDGFMHCTTS-GTLGSLLPDTV 752
Query: 539 ISTPCNVTCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENNVAFSLKNSF 718
+S+P + + + V V + QG
Sbjct: 753 LSSPLSHRSKRSLSCRPPMVKLVCPADNPRAQGLE------------------------- 787
Query: 719 CEQTCDDVINKQHPTHICDEGCKCQSGYVRNSNNTCVPTSECFRCEVNGVTWQNGQTKKD 898
C +TC + + + + C GC C G VR+ N CV C C G + G T K
Sbjct: 788 CAKTCQN-YDLERMSLGCVSGCLCPPGMVRHENK-CVALERC-PCFHQGAEYAPGDTVK- 843
Query: 899 VYACRLFIC 925
C +C
Sbjct: 844 -IGCNTCVC 851
Score = 52.8 bits (125), Expect = 1e-06
Identities = 30/111 (27%), Positives = 41/111 (36%), Gaps = 8/111 (7%)
Frame = +2
Query: 200 STACVAPKKLLSCV--NP------CEIRCGDLSKKCSNVDCIESCACPDNMLEQDGTCVQ 355
S +C P L C NP C C + + ++ C+ C CP M+ + CV
Sbjct: 764 SLSCRPPMVKLVCPADNPRAQGLECAKTCQNYDLERMSLGCVSGCLCPPGMVRHENKCVA 823
Query: 356 KTDCRCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGKWICTKNIC 508
C C E P CN C CR+ KW CT ++C
Sbjct: 824 LERCPC-----------FHQGAEYAPGDTVKIGCNTCVCRERKWNCTNHVC 863
Score = 35.0 bits (79), Expect = 0.30
Identities = 48/214 (22%), Positives = 76/214 (35%), Gaps = 11/214 (5%)
Frame = +2
Query: 257 RCGDLSKKCSNVDCIESCACPDNMLEQ---DGTCVQKTDCRCTWNADLLGPKPIGYNEES 427
+C D K +V C +N+++Q D C T L+ P+P Y +
Sbjct: 1030 QCADTRKLSLDVS---PATCHNNIMKQTMVDSACRILTSDVFQGCNRLVDPEP--YLDIC 1084
Query: 428 LPDTIFTKDCNNCSCRQGKWICTKNICTKDCQWSDWKISTPCNVTCGQGIQILERTVARV 607
+ DT + +C+C ++C + Q W+ T C +C + +
Sbjct: 1085 IYDTCSCESIGDCACFCDTIAAYAHVCAQHGQVVAWRTPTLCPQSCEE----------KN 1134
Query: 608 AQYEGKDCQGSNRTEEMCYAATKCCENNVAFSLKNSFCEQTCDDVINKQHPTHI-----C 772
+ G +C+ + C A C TC QHP + C
Sbjct: 1135 VRENGYECEWRYNS---CAPA----------------CPVTC------QHPEPLACPVQC 1169
Query: 773 DEGC--KCQSGYVRNS-NNTCVPTSECFRCEVNG 865
EGC C G + + TCV +C CEV G
Sbjct: 1170 VEGCHAHCPPGRILDELLQTCVDPQDCPVCEVAG 1203
Score = 34.3 bits (77), Expect = 0.51
Identities = 26/105 (24%), Positives = 41/105 (39%), Gaps = 1/105 (0%)
Frame = +2
Query: 197 CSTACVAPKKLLSCVNPCEIRCGDLSKKCSNVDCIESCACPDNMLEQDGTCVQKTDCRCT 376
C+ +C C C C + C + E C CP + + +G+CV + C
Sbjct: 2199 CAMSCPPSLVYNHCERGCPRHCDGNTSFCGDHPS-EGCFCPQHQVFLEGSCVPEEACTQC 2257
Query: 377 WNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGKWI-CTKNIC 508
D + + + E +PD + C C C G+ I CT C
Sbjct: 2258 VGEDGVRHQ---FLETWVPD---HQPCQICMCLSGRKINCTAQPC 2296
Score = 31.2 bits (69), Expect = 4.3
Identities = 26/85 (30%), Positives = 29/85 (34%), Gaps = 5/85 (5%)
Frame = +2
Query: 233 SCVNPCEIRCGDLSKKCSNVDCIESC--ACPDNML--EQDGTCVQKTDCR-CTWNADLLG 397
SC C + C V C+E C CP + E TCV DC C L
Sbjct: 1148 SCAPACPVTCQHPEPLACPVQCVEGCHAHCPPGRILDELLQTCVDPQDCPVCEVAGRRLA 1207
Query: 398 PKPIGYNEESLPDTIFTKDCNNCSC 472
P G PD C NC C
Sbjct: 1208 P---GKKITLSPDD--PAHCQNCHC 1227
>sp|P80012|VWF_BOVIN Von Willebrand factor precursor (vWF)
Length = 937
Score = 76.3 bits (186), Expect = 1e-13
Identities = 39/144 (27%), Positives = 61/144 (42%), Gaps = 1/144 (0%)
Frame = +2
Query: 92 SCGNGMVTKTPQEVIKAVNGGKDCDVIYEPCFLGNCSTACVAPKKLLSCVNPCEIRCGDL 271
+C G+ P + A K ++Y +C C + CV+PC C L
Sbjct: 255 ACAQGLRCPCPVLLEYARACAKQGMLLYGWADHSSCRPDCPTGMEYKECVSPCHRTCRSL 314
Query: 272 S-KKCSNVDCIESCACPDNMLEQDGTCVQKTDCRCTWNADLLGPKPIGYNEESLPDTIFT 448
S + C++ C+CP+ L +G CV+ T+C C P P P +
Sbjct: 315 SITEVCREQCVDGCSCPEGQLLDEGRCVESTECPCVHAGK---PYP--------PGASLS 363
Query: 449 KDCNNCSCRQGKWICTKNICTKDC 520
+DCN C CR +W+C+ C +C
Sbjct: 364 RDCNTCICRNSQWVCSNEDCPGEC 387
Score = 54.7 bits (130), Expect = 4e-07
Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 4/106 (3%)
Frame = +2
Query: 176 EPCFLGNCSTACVAPKKLLSCVNPCEIRCGDLS---KKCSNVDCIESCACPDNM-LEQDG 343
EP F C+ +C + C PC + C LS ++C+ V C+E C CP + L++ G
Sbjct: 643 EPSF---CALSCPHGQVYQQCGTPCNLTCRSLSHPDEECTEV-CLEGCFCPPGLFLDETG 698
Query: 344 TCVQKTDCRCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQG 481
+CV K C C ++ ++ P+ IF+ C C G
Sbjct: 699 SCVPKAQCPCYYDGEIF-----------QPEDIFSDHHTMCYCEDG 733
Score = 51.2 bits (121), Expect = 4e-06
Identities = 23/91 (25%), Positives = 33/91 (36%)
Frame = +2
Query: 248 CEIRCGDLSKKCSNVDCIESCACPDNMLEQDGTCVQKTDCRCTWNADLLGPKPIGYNEES 427
C C + +C + C+ C M+ + CV C C E
Sbjct: 787 CTKTCQNYDLECMSTGCVSGCLPAPGMVRHENRCVALERCPC-----------FHQGREY 835
Query: 428 LPDTIFTKDCNNCSCRQGKWICTKNICTKDC 520
P DCN+C C+ KW CT ++C C
Sbjct: 836 APGDRVKVDCNSCVCQDRKWNCTDHVCDASC 866
Score = 36.2 bits (82), Expect = 0.13
Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 4/70 (5%)
Frame = +2
Query: 680 CENNVAFSLKNSFCEQTCDDVINKQHP----THICDEGCKCQSGYVRNSNNTCVPTSECF 847
C + + + C TC + HP T +C EGC C G + +CVP ++C
Sbjct: 651 CPHGQVYQQCGTPCNLTCRSL---SHPDEECTEVCLEGCFCPPGLFLDETGSCVPKAQC- 706
Query: 848 RCEVNGVTWQ 877
C +G +Q
Sbjct: 707 PCYYDGEIFQ 716
>sp|Q28295|VWF_CANFA Von Willebrand factor precursor (vWF)
Length = 2813
Score = 71.2 bits (173), Expect = 4e-12
Identities = 32/109 (29%), Positives = 47/109 (43%), Gaps = 1/109 (0%)
Frame = +2
Query: 197 CSTACVAPKKLLSCVNPCEIRCGDLS-KKCSNVDCIESCACPDNMLEQDGTCVQKTDCRC 373
C AC A + CV+PC C L K+ C++ C+CP+ L +G CV +C C
Sbjct: 291 CRPACPAGMEYKECVSPCTRTCQSLHVKEVCQEQCVDGCSCPEGQLLDEGHCVGSAECSC 350
Query: 374 TWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGKWICTKNICTKDC 520
+ + P +DC+ C CR WIC+ C +C
Sbjct: 351 -----------VHAGQRYPPGASLLQDCHTCICRNSLWICSNEECPGEC 388
Score = 62.8 bits (151), Expect = 1e-09
Identities = 63/252 (25%), Positives = 97/252 (38%), Gaps = 7/252 (2%)
Frame = +2
Query: 191 GNCSTACVAPKKLLSCVNPCEIRCGDLS---KKCSNVDCIESCACPDNM-LEQDGTCVQK 358
G C+ +C + L C PC + C LS + C+ V C+E C CP + L++ G CV K
Sbjct: 646 GFCALSCPQGQVYLQCGTPCNMTCRSLSYPEEDCNEV-CLEGCFCPPGLYLDERGDCVPK 704
Query: 359 TDCRCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGKWICTKNICTKDCQWSDWK 538
C C ++ ++ P+ IF+ C C G CT
Sbjct: 705 AQCPCYYDGEIF-----------QPEDIFSDHHTMCYCEDGFMHCT-------------- 739
Query: 539 ISTPCNVTCGQGIQILERTVARVAQYEGK---DCQGSNRTEEMCYAATKCCENNVAFSLK 709
+ G G + ++ + K C+ + +C A +N A L+
Sbjct: 740 ------TSGGLGSLLPNPVLSSPRSHRSKRSLSCR-PPMVKLVCPA-----DNPRAEGLE 787
Query: 710 NSFCEQTCDDVINKQHPTHICDEGCKCQSGYVRNSNNTCVPTSECFRCEVNGVTWQNGQT 889
C +TC + + Q + C GC C G VR+ N CV C C G + G+T
Sbjct: 788 ---CAKTCQN-YDLQCMSTGCVSGCLCPQGMVRHENR-CVALERC-PCFHQGQEYAPGET 841
Query: 890 KKDVYACRLFIC 925
K C +C
Sbjct: 842 VK--IDCNTCVC 851
Score = 62.4 bits (150), Expect = 2e-09
Identities = 33/115 (28%), Positives = 43/115 (37%), Gaps = 8/115 (6%)
Frame = +2
Query: 200 STACVAPKKLLSCV--NP------CEIRCGDLSKKCSNVDCIESCACPDNMLEQDGTCVQ 355
S +C P L C NP C C + +C + C+ C CP M+ + CV
Sbjct: 764 SLSCRPPMVKLVCPADNPRAEGLECAKTCQNYDLQCMSTGCVSGCLCPQGMVRHENRCVA 823
Query: 356 KTDCRCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGKWICTKNICTKDC 520
C C +E P DCN C CR KW CT ++C C
Sbjct: 824 LERCPC-----------FHQGQEYAPGETVKIDCNTCVCRDRKWNCTDHVCDATC 867
Score = 35.4 bits (80), Expect = 0.23
Identities = 25/106 (23%), Positives = 41/106 (38%), Gaps = 2/106 (1%)
Frame = +2
Query: 197 CSTACVAPKKLLSCVNPCEIRCGDLSKKCSNVDCIESCACPDNMLEQDGTCVQKTDCRCT 376
C+ +C C + C C + C + E C CP N + +G+CV + C
Sbjct: 2199 CAMSCPPSLVYNHCEHGCPRLCEGNTSSCGDQPS-EGCFCPPNQVMLEGSCVPEEACTQC 2257
Query: 377 WNADLLGPKPIGYNEESLPDTI-FTKDCNNCSCRQGKWI-CTKNIC 508
+ D G + L + + C C+C G+ + CT C
Sbjct: 2258 ISED-------GVRHQFLETWVPAHQPCQICTCLSGRKVNCTLQPC 2296
Score = 31.2 bits (69), Expect = 4.3
Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Frame = +2
Query: 719 CEQTCDDVINKQHPTHICDEGCKCQSGYVRNSNNTCVPTSECFRCEVNGVTWQNGQT-KK 895
C +TC + K+ C +GC C G + + + CV ++EC C G + G + +
Sbjct: 308 CTRTCQSLHVKEVCQEQCVDGCSCPEGQLLDEGH-CVGSAEC-SCVHAGQRYPPGASLLQ 365
Query: 896 DVYAC----RLFIC 925
D + C L+IC
Sbjct: 366 DCHTCICRNSLWIC 379
Score = 30.0 bits (66), Expect = 9.6
Identities = 44/200 (22%), Positives = 72/200 (36%), Gaps = 16/200 (8%)
Frame = +2
Query: 314 CPDNMLEQ---DGTCVQKT-----DCRCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCS 469
C +N+++Q D +C T DC L+ P+P + + + DT + +C+
Sbjct: 1046 CHNNIMKQTMVDSSCRILTSDIFQDCN-----RLVDPEP--FLDICIYDTCSCESIGDCT 1098
Query: 470 CRQGKWICTKNICTKDCQWSDWKISTPCNVTCGQGIQILERTVARVAQYEGKDCQGSNRT 649
C ++C + + W+ +T C C + R G +C+ +
Sbjct: 1099 CFCDTIAAYAHVCAQHGKVVAWRTATFCPQNCEE----------RNLHENGYECEWRYNS 1148
Query: 650 EEMCYAATKCCENNVAFSLKNSFCEQTCDDVINKQHPTHI-----CDEGCK--CQSGYVR 808
C A C TC QHP + C EGC C G +
Sbjct: 1149 ---CAPA----------------CPITC------QHPEPLACPVQCVEGCHAHCPPGKIL 1183
Query: 809 NSN-NTCVPTSECFRCEVNG 865
+ TC+ +C CEV G
Sbjct: 1184 DELLQTCIDPEDCPVCEVAG 1203
>sp|Q02817|MUC2_HUMAN Mucin-2 precursor (Intestinal mucin 2)
Length = 5179
Score = 70.5 bits (171), Expect = 6e-12
Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 9/114 (7%)
Frame = +2
Query: 206 ACVAPKKLLSCVN--------PCEIRCGDLSKKCSNVDCIESCACPDNMLEQD-GTCVQK 358
+C APK + C N P + C L+ + +C+ C CPD +++ G CV +
Sbjct: 758 SCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVE 817
Query: 359 TDCRCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGKWICTKNICTKDC 520
+C C N DL DCN C+C++G+W+CT+ +C C
Sbjct: 818 KECPCVHNNDLYSS-----------GAKIKVDCNTCTCKRGRWVCTQAVCHGTC 860
Score = 47.8 bits (112), Expect = 4e-05
Identities = 34/121 (28%), Positives = 45/121 (37%), Gaps = 11/121 (9%)
Frame = +2
Query: 191 GNCSTACVAPKKL------LSCVNPCEIRCGDL--SKKCSNVDCIESCACPDNMLEQD-- 340
GN TA + PK L +PC C L S C ++ C CP+ + D
Sbjct: 283 GNWRTATLCPKTCPGNLVYLESGSPCMDTCSHLEVSSLCEE-HRMDGCFCPEGTVYDDIG 341
Query: 341 -GTCVQKTDCRCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGKWICTKNICTKD 517
CV + C C + L P +E T DC C C G+W+C C
Sbjct: 342 DSGCVPVSQCHCRLHGHLYTP-----GQE------ITNDCEQCVCNAGRWVCKDLPCPGT 390
Query: 518 C 520
C
Sbjct: 391 C 391
Score = 37.0 bits (84), Expect = 0.079
Identities = 28/111 (25%), Positives = 44/111 (39%), Gaps = 3/111 (2%)
Frame = +2
Query: 191 GNCSTACVAPKKLLSCVNPCEIRCGDLSKKCSNVDCIESCACPDNMLE-QDGTCVQKTDC 367
G C C + ++ +C E C S + +N +E C CP+ + G V C
Sbjct: 4756 GACLVECPSHREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTC 4815
Query: 368 RCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQG--KWICTKNICTK 514
C ++ P+ G + F DC NC C +G IC C++
Sbjct: 4816 GCVGPDNV--preFGEH--------FEFDCKNCVCLEGGSGIICQPKRCSQ 4856
Score = 32.7 bits (73), Expect = 1.5
Identities = 17/70 (24%), Positives = 29/70 (41%), Gaps = 5/70 (7%)
Frame = +2
Query: 650 EEMCYAATKCCENNVAFSLKNSFCEQTCDDVINKQHPTHICD-----EGCKCQSGYVRNS 814
E +C C N+ F + C+QTC + + +H + +GC C +
Sbjct: 651 EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSL--SEADSHCLEGFAPVDGCGCPDHTFLDE 708
Query: 815 NNTCVPTSEC 844
CVP ++C
Sbjct: 709 KGRCVPLAKC 718
>sp|Q9HC84|MUC5B_HUMAN Mucin-5B precursor (Mucin 5 subtype B, tracheobronchial) (High
molecular weight salivary mucin MG1) (Sublingual gland
mucin)
Length = 5703
Score = 65.1 bits (157), Expect = 3e-10
Identities = 34/117 (29%), Positives = 46/117 (39%), Gaps = 10/117 (8%)
Frame = +2
Query: 200 STACVAPKKLLSCVNP--------CEIRCGDLSKKCSNVDCIESCACPDNMLEQ-DGTCV 352
ST C AP L C N C C L C + C+ C CP ++ G C+
Sbjct: 792 STGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCI 851
Query: 353 QKTDCRCTWNADLLGPKPIGYNEESL-PDTIFTKDCNNCSCRQGKWICTKNICTKDC 520
+ DC C +NE + P DCN C+CR +W C+ +C C
Sbjct: 852 AEEDCPCV------------HNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTC 896
Score = 47.8 bits (112), Expect = 4e-05
Identities = 54/234 (23%), Positives = 82/234 (35%), Gaps = 7/234 (2%)
Frame = +2
Query: 209 CVAPKKLLSCVNPCEIRCGDLSKKCSNVDC------IESCACP-DNMLEQDGTCVQKTDC 367
C ++ V+ C+ C LS+ ++V C ++ C CP L G CV +C
Sbjct: 696 CPKSQRYAYVVDACQPTCRGLSE--ADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQEC 753
Query: 368 RCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGKWICTKNICTKDCQWSDWKIST 547
C + +L P + ++E ++ CSC GK C K ST
Sbjct: 754 PCYAHGTVLAPGEVVHDEGAV-----------CSCTGGKLSCLGASLQK---------ST 793
Query: 548 PCNVTCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENNVAFSLKNSFCEQ 727
C A DC S+ A T E C +
Sbjct: 794 GC-----------------AAPMVYLDCSNSS-------AGTPGAE-----------CLR 818
Query: 728 TCDDVINKQHPTHICDEGCKCQSGYVRNSNNTCVPTSECFRCEVNGVTWQNGQT 889
+C + TH C GC C G V + + C+ +C C N T++ G+T
Sbjct: 819 SCHTLDVGCFSTH-CVSGCVCPPGLVSDGSGGCIAEEDC-PCVHNEATYKPGET 870
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/113 (23%), Positives = 37/113 (32%), Gaps = 5/113 (4%)
Frame = +2
Query: 197 CSTACVAPKKLLSCVNPCEIRCGDLSKKCSNVD-CIESCACPDNMLEQDGT----CVQKT 361
C C + C +PC C + + D C++ C CP D C+
Sbjct: 325 CPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGSTVLDDITHSGCLPLG 384
Query: 362 DCRCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGKWICTKNICTKDC 520
C CT P T F C++C+C G W C C C
Sbjct: 385 QCPCTHGGRTYSP-----------GTSFNTTCSSCTCSGGLWQCQDLPCPGTC 426
Score = 34.7 bits (78), Expect = 0.39
Identities = 22/95 (23%), Positives = 37/95 (38%), Gaps = 3/95 (3%)
Frame = +2
Query: 623 KDCQGSNRTEEMCYAATKCCENNVAFSLKNSFCEQTCDDVINKQ---HPTHICDEGCKCQ 793
K Q S+ + +C + C + ++ C+ TC + + + +GC C
Sbjct: 677 KGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCP 736
Query: 794 SGYVRNSNNTCVPTSECFRCEVNGVTWQNGQTKKD 898
+G N CVP EC C +G G+ D
Sbjct: 737 AGTFLNDAGACVPAQEC-PCYAHGTVLAPGEVVHD 770
Score = 30.0 bits (66), Expect = 9.6
Identities = 23/83 (27%), Positives = 32/83 (38%), Gaps = 3/83 (3%)
Frame = +2
Query: 644 RTEEMCYAATKCCENNVAFSLKNSFCEQTCDDVINKQHPTHICDEGCKCQSGYVRNSNNT 823
R E+C + C N+ S C TC + Q C +GC C G + T
Sbjct: 320 RCPELC---PRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGSTVLDDIT 376
Query: 824 ---CVPTSECFRCEVNGVTWQNG 883
C+P +C C G T+ G
Sbjct: 377 HSGCLPLGQC-PCTHGGRTYSPG 398
>sp|Q28833|VWF_PIG Von Willebrand factor precursor (vWF)
Length = 2482
Score = 64.3 bits (155), Expect = 5e-10
Identities = 61/249 (24%), Positives = 93/249 (37%), Gaps = 4/249 (1%)
Frame = +2
Query: 191 GNCSTACVAPKKLLSCVNPCEIRCGDLS---KKCSNVDCIESCACPDNM-LEQDGTCVQK 358
G C+ +C + L C PC + C LS ++C+ DC+E C CP + L+ G CV K
Sbjct: 320 GFCALSCPPGQVYLQCGTPCNLTCRSLSYPDEECAE-DCLEGCFCPPGLYLDGSGDCVPK 378
Query: 359 TDCRCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGKWICTKNICTKDCQWSDWK 538
C C + ++ P+ IF+ C C G C++ Q +
Sbjct: 379 AQCPCYHDGEIF-----------QPEDIFSDHHTMCYCEDGFMHCSRAGAPGSLQ-PEVV 426
Query: 539 ISTPCNVTCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENNVAFSLKNSF 718
+S+P + + + V V + +G K C+N + L+
Sbjct: 427 LSSPLSHRSKRSLSCRPPMVKLVCPADNPRAEG--------LECAKTCQN---YDLE--- 472
Query: 719 CEQTCDDVINKQHPTHICDEGCKCQSGYVRNSNNTCVPTSECFRCEVNGVTWQNGQTKKD 898
C T C GC C G VR+ N CV C C G + G+T K
Sbjct: 473 CVSTG------------CVSGCLCPPGMVRHENR-CVALQRC-PCFHQGREYAPGETVK- 517
Query: 899 VYACRLFIC 925
C +C
Sbjct: 518 -VDCNTCVC 525
Score = 63.2 bits (152), Expect = 1e-09
Identities = 48/216 (22%), Positives = 73/216 (33%), Gaps = 45/216 (20%)
Frame = +2
Query: 8 CPVNCKALTYQTSECIKEC-----------------SVNDSQCDPSCGNGMVTKTPQEVI 136
C + C++L+Y EC ++C V +QC P +G + + P+++
Sbjct: 339 CNLTCRSLSYPDEECAEDCLEGCFCPPGLYLDGSGDCVPKAQC-PCYHDGEIFQ-PEDIF 396
Query: 137 KAVNGGKDCDVIYEPCFLGNC--------------------STACVAPKKLLSCV--NP- 247
+ C+ + C S +C P L C NP
Sbjct: 397 SDHHTMCYCEDGFMHCSRAGAPGSLQPEVVLSSPLSHRSKRSLSCRPPMVKLVCPADNPR 456
Query: 248 -----CEIRCGDLSKKCSNVDCIESCACPDNMLEQDGTCVQKTDCRCTWNADLLGPKPIG 412
C C + +C + C+ C CP M+ + CV C C
Sbjct: 457 AEGLECAKTCQNYDLECVSTGCVSGCLCPPGMVRHENRCVALQRCPC-----------FH 505
Query: 413 YNEESLPDTIFTKDCNNCSCRQGKWICTKNICTKDC 520
E P DCN C CR KW CT ++C C
Sbjct: 506 QGREYAPGETVKVDCNTCVCRDRKWSCTDHVCDASC 541
Score = 56.2 bits (134), Expect = 1e-07
Identities = 21/73 (28%), Positives = 33/73 (45%)
Frame = +2
Query: 302 ESCACPDNMLEQDGTCVQKTDCRCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQG 481
+ C+CP+ L DG CV+ +C C + + P ++DCN C CR
Sbjct: 1 DGCSCPEGQLLDDGRCVESAECSCVHSG-----------KRYPPGASLSRDCNTCICRNS 49
Query: 482 KWICTKNICTKDC 520
W+C+ C +C
Sbjct: 50 LWVCSNEDCPGEC 62
Score = 33.9 bits (76), Expect = 0.67
Identities = 25/105 (23%), Positives = 42/105 (40%), Gaps = 1/105 (0%)
Frame = +2
Query: 197 CSTACVAPKKLLSCVNPCEIRCGDLSKKCSNVDCIESCACPDNMLEQDGTCVQKTDCRCT 376
C+ +C C + C C S C + E C CP + + +CV + C
Sbjct: 1868 CAVSCPPSLVYNHCEHGCPRHCEGNSSSCGDHPS-EGCFCPPHQVMLGSSCVPEEACTQC 1926
Query: 377 WNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGKWI-CTKNIC 508
+ D + + + E +PD + C C+C G+ + CT C
Sbjct: 1927 VDDDGIRHQ---FLETWVPD---HQPCQICTCLSGRRVNCTLQPC 1965
>sp|O88799|ZAN_MOUSE Zonadhesin precursor
Length = 5376
Score = 62.8 bits (151), Expect = 1e-09
Identities = 64/255 (25%), Positives = 88/255 (34%), Gaps = 7/255 (2%)
Frame = +2
Query: 146 NGGKDCDVIYEPCFLGNCSTACVAPKKLLSCVNPCEIRCGDLSKKCSNVDCIESCACPDN 325
NG +C I C + T C+ P + SC N CE+ + C E C C
Sbjct: 3288 NGSSNCTEITLQCPTNSQFTDCL-PSCVPSCSNRCEVTSPSVPSSCR-----EGCLCNHG 3341
Query: 326 MLEQDGTCVQKTDCRCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGKWICTKNI 505
+ + CV +T C C KD GK +K
Sbjct: 3342 FVFSEDKCVPRTQCGC-------------------------KDARGAIIPAGKTWTSKG- 3375
Query: 506 CTKDCQWSDWKISTPCNVTCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCE 685
CT+ C + N+ C Q Q T C+ ++ C T C
Sbjct: 3376 CTQSCACVEG------NIQC-QNFQCPPETY----------CKDNSEGSSTCTKITLQCP 3418
Query: 686 NNVAFSLKNSFC-------EQTCDDVINKQHPTHICDEGCKCQSGYVRNSNNTCVPTSEC 844
+ ++ C E C D+ K T C EGC CQSGYV NS+ CV +EC
Sbjct: 3419 AHTQYTSCLPSCLPSCLDPEGLCKDISPKVPST--CKEGCVCQSGYVLNSDK-CVLRAEC 3475
Query: 845 FRCEVNGVTWQNGQT 889
+ G G+T
Sbjct: 3476 DCKDAQGALIPAGKT 3490
Score = 59.3 bits (142), Expect = 1e-08
Identities = 77/356 (21%), Positives = 109/356 (30%), Gaps = 69/356 (19%)
Frame = +2
Query: 8 CPVNCKALTYQTS---ECIKECSVNDSQCDPS-------------CGNGMVTKTPQEVIK 139
CP+ C A ++ T+ C C DS+C+ S C V + V++
Sbjct: 2336 CPLECPAHSHYTNCLPSCPPSCLDPDSRCEGSGHKVPATCREGCICQPDYVLLNDKCVLR 2395
Query: 140 AVNGGKDCDVIYEP---------------CFLG-----------------------NC-- 199
+ G KD ++ P C G NC
Sbjct: 2396 SHCGCKDAQGVFIPAGKTWISEDCTQSCTCMKGSMRCWDFQCPPGTYCKNSNDGSSNCVK 2455
Query: 200 -STACVAPKKLLSCVNPCEIRCGDLSKKCSNV------DCIESCACPDNMLEQDGTCVQK 358
S C A K C+ PC C D C + +C E C C + ++ CV +
Sbjct: 2456 ISLQCPAHSKFTDCLPPCHPSCSDPDGHCEGISTNAHSNCKEGCVCQPGYVLRNDKCVLR 2515
Query: 359 TDCRCTWNADLLGPKPIGYNEESLPDTIFTKDCN-NCSCRQGKWICTKNICTKDCQWSDW 535
+C C G P G N S + C+ +C C +G C C
Sbjct: 2516 IECGCQHTQG--GFIPAGKNWTS-------RGCSQSCDCMEGVIRCQNFQCPS------- 2559
Query: 536 KISTPCNVTCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENNVAFSLKNS 715
G CQ C T C + +F+
Sbjct: 2560 ----------------------------GTYCQDIEDGTSNCANITLQCPAHSSFTNCLP 2591
Query: 716 FCEQTCDDVI-----NKQHPTHICDEGCKCQSGYVRNSNNTCVPTSECFRCEVNGV 868
C+ +C D + C EGC C+ YV NN CVP EC + GV
Sbjct: 2592 PCQPSCSDPEGHCGGSTTKAPSACQEGCVCEPDYVV-LNNKCVPRIECGCKDAQGV 2646
Score = 56.6 bits (135), Expect = 1e-07
Identities = 55/247 (22%), Positives = 85/247 (34%), Gaps = 15/247 (6%)
Frame = +2
Query: 194 NCSTA---CVAPKKLLSCVNPCEIRCGDLSKKCSNVD------CIESCACPDNMLEQDGT 346
+C+T C A +C+ PC+ C D C C E C C + + +
Sbjct: 2932 SCATITLQCPAHSHFTNCLPPCQPSCLDSEGHCEGSTTKAPSACQEGCVCEPDYVVLNNK 2991
Query: 347 CVQKTDCRCTWNADLLGPKPIGYNEESLPDTIFTKDCN-NCSCRQGKWICTKNICTKDCQ 523
CV + +C C +L P T + C +C+C+ G C K C
Sbjct: 2992 CVPRIECGCKDAQGVLIPAD---------KTWINRGCTQSCTCKGGAIQCQKFQC----- 3037
Query: 524 WSDWKISTPCNVTCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENNVAFS 703
P C KD + N C + C N F+
Sbjct: 3038 --------PSETYC-------------------KDIEDGNSN---CTRISLQCPANSNFT 3067
Query: 704 LKNSFCEQTCDDVI-----NKQHPTHICDEGCKCQSGYVRNSNNTCVPTSECFRCEVNGV 868
C+ +C + + + C EGC CQSGYV + N+ C+ ++C + G
Sbjct: 3068 SCLPSCQPSCSNTDVHCEGSSPNTLSSCREGCVCQSGYVLH-NDKCILRNQCGCKDAQGA 3126
Query: 869 TWQNGQT 889
G+T
Sbjct: 3127 LIPEGKT 3133
Score = 55.1 bits (131), Expect = 3e-07
Identities = 58/230 (25%), Positives = 81/230 (35%), Gaps = 2/230 (0%)
Frame = +2
Query: 161 CDVIYEPCFLGNCSTACVAPKKLLSCVNPCEIRCGDLSKKCSNVDCIESCACPDNMLEQD 340
C I C + T C+ P L SC +P E CG S + + C E C C + + ++
Sbjct: 4257 CSKITVQCPAHSQYTTCL-PSCLPSCFDP-EGLCGGASPRAPST-CREGCVCEADYVLRE 4313
Query: 341 GTCVQKTDCRC-TWNADLLGPKPIGYNEESLPDTIFTKDC-NNCSCRQGKWICTKNICTK 514
CV +T C C DL+ T T+ C C+C+ G C
Sbjct: 4314 DKCVLRTQCGCKDAQGDLIPAN----------KTWLTRGCAQKCTCKGGNIHC------- 4356
Query: 515 DCQWSDWKISTPCNVTCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENNV 694
W P C + Q C + + C N
Sbjct: 4357 ------WNFKCPLGTECKDSVDGGSNCTKIALQ-----CPAHSHHTYCLPSCIPSCSN-- 4403
Query: 695 AFSLKNSFCEQTCDDVINKQHPTHICDEGCKCQSGYVRNSNNTCVPTSEC 844
N CE T + Q P+ C EGC C SG+V S + CVP ++C
Sbjct: 4404 ----VNDRCEST-----SLQRPS-TCIEGCLCHSGFV-FSKDKCVPRTQC 4442
Score = 55.1 bits (131), Expect = 3e-07
Identities = 71/319 (22%), Positives = 106/319 (33%), Gaps = 21/319 (6%)
Frame = +2
Query: 32 TYQTSECIKECSVNDS--QC-DPSCGNGMVTKTPQEVIKAVNGGKDCDVIYEPCFLGNCS 202
T+ + C K C+ QC D SC G E G +C C +
Sbjct: 4577 TWVSRGCTKNCTCKGGTVQCHDFSCPTGSRCLDNNE------GNSNCVTYALKCPAHSLY 4630
Query: 203 TACVAPKKLLSCVNPCEIRCGDLSKKCSNVDCIESCACPDNMLEQDGTCVQKTDCRCTWN 382
T C+ P L SC +P E CG S + + C E C C + C+ + C C
Sbjct: 4631 TNCL-PSCLPSCSDP-EGLCGGTSPEVPST-CKEGCICQSGYVLHKNKCMLRIHCDC--- 4684
Query: 383 ADLLGPKPIGYNEESLPDTIFTKDCNN-CSCRQGKWICTKNICTKDCQWSDWKISTPCNV 559
K + T + C+ C+C+ G + C C
Sbjct: 4685 ------KDFQGSLIKTGQTWISSGCSKICTCKGGFFQCQSYKCPS--------------- 4723
Query: 560 TCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENNVAFSLKNSFCEQTCDD 739
G C+ S C ++T C N ++ C +C +
Sbjct: 4724 --------------------GTQCEESEDGSSNCVSSTMKCPANSLYTHCLPTCLPSCSN 4763
Query: 740 VINKQHPTH-----ICDEGCKCQSGYVRNSNNTCVPTSECFRCEVN------GVTW---- 874
+ T C EGC CQ GY+ N +TCV ++C ++ G TW
Sbjct: 4764 PDGRCEGTSHKAPSTCREGCVCQPGYLLN-KDTCVHKNQCGCKDIRGNIIPAGNTWISSD 4822
Query: 875 --QNGQTKKDVYACRLFIC 925
Q+ V C+ F+C
Sbjct: 4823 CTQSCACTDGVIQCQNFVC 4841
Score = 54.7 bits (130), Expect = 4e-07
Identities = 60/271 (22%), Positives = 85/271 (31%), Gaps = 27/271 (9%)
Frame = +2
Query: 194 NCSTA---CVAPKKLLSCVNPCEIRCGDLSKKCSNVD------CIESCACPDNMLEQDGT 346
NC++ C A +C+ C+ C D C C E C C + + +
Sbjct: 2812 NCTSIPLQCPAHSHYTNCLPTCQPSCSDPDGHCEGSSTKAPSACKEGCVCEPDYVMLNNK 2871
Query: 347 CVQKTDCRCTWNADLLGPKPIGYNEESLPDTIFTKDC-NNCSCRQGKWICTKNICTKDCQ 523
CV + +C C +L P T + C +C+CR G C K C+
Sbjct: 2872 CVPRIECGCKDTQGVLIP---------ADKTWINRGCTQSCTCRGGAIQCQKYHCS---- 2918
Query: 524 WSDWKISTPCNVTCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENNVAFS 703
G C+ C T C + F+
Sbjct: 2919 -------------------------------SGTYCKDMEDDSSSCATITLQCPAHSHFT 2947
Query: 704 LKNSFCEQTCDDVI-----NKQHPTHICDEGCKCQSGYVRNSNNTCVPTSECFRCEVNGV 868
C+ +C D + C EGC C+ YV NN CVP EC + GV
Sbjct: 2948 NCLPPCQPSCLDSEGHCEGSTTKAPSACQEGCVCEPDYV-VLNNKCVPRIECGCKDAQGV 3006
Query: 869 ------TW------QNGQTKKDVYACRLFIC 925
TW Q+ K C+ F C
Sbjct: 3007 LIPADKTWINRGCTQSCTCKGGAIQCQKFQC 3037
Score = 54.3 bits (129), Expect = 5e-07
Identities = 58/249 (23%), Positives = 82/249 (32%), Gaps = 17/249 (6%)
Frame = +2
Query: 194 NC---STACVAPKKLLSCVNPCEIRCGDLSKKCSNVD------CIESCAC-PDNMLEQDG 343
NC + C A C+ PC+ C D C C E C C PD +L D
Sbjct: 4496 NCVEITVQCPAHSHYSKCLPPCQPSCSDPDGHCEGTSPEAPSTCEEGCVCEPDYVLSND- 4554
Query: 344 TCVQKTDCRCTWNADLLGPKPIGYNEESLPDTIFTKDCN-NCSCRQGKWICTKNICTKDC 520
CV ++C C +L P+ T ++ C NC+C+ G C C
Sbjct: 4555 KCVPSSECGCKDAHGVLIPES---------KTWVSRGCTKNCTCKGGTVQCHDFSCPT-- 4603
Query: 521 QWSDWKISTPCNVTCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENNVAF 700
G C +N C C + +
Sbjct: 4604 ---------------------------------GSRCLDNNEGNSNCVTYALKCPAHSLY 4630
Query: 701 SLKNSFCEQTCDDV------INKQHPTHICDEGCKCQSGYVRNSNNTCVPTSECFRCEVN 862
+ C +C D + + P+ C EGC CQSGYV + N C+ C +
Sbjct: 4631 TNCLPSCLPSCSDPEGLCGGTSPEVPS-TCKEGCICQSGYVLHKNK-CMLRIHCDCKDFQ 4688
Query: 863 GVTWQNGQT 889
G + GQT
Sbjct: 4689 GSLIKTGQT 4697
Score = 52.0 bits (123), Expect = 2e-06
Identities = 48/173 (27%), Positives = 68/173 (39%), Gaps = 6/173 (3%)
Frame = +2
Query: 32 TYQTSECIKECSVNDS--QCDP-SCGNGMVTKTPQEVIKAVNGGKDCDVIYEPCFLGNCS 202
T+ +S C K C+ QC C +G + ++ G +C C +
Sbjct: 4697 TWISSGCSKICTCKGGFFQCQSYKCPSGTQCEESED------GSSNCVSSTMKCPANSLY 4750
Query: 203 TACVAPKKLLSCVNPCEIRCGDLSKKCSNVDCIESCACPDNMLEQDGTCVQKTDCRCTWN 382
T C+ P L SC NP + RC S K + C E C C L TCV K C C
Sbjct: 4751 THCL-PTCLPSCSNP-DGRCEGTSHKAPST-CREGCVCQPGYLLNKDTCVHKNQCGC--- 4804
Query: 383 ADLLGPKPIGYNEESLPDTIFTKDC-NNCSCRQGKWICTKNICT--KDCQWSD 532
K I N +T + DC +C+C G C +C CQ+++
Sbjct: 4805 ------KDIRGNIIPAGNTWISSDCTQSCACTDGVIQCQNFVCPSGSHCQYNE 4851
Score = 51.6 bits (122), Expect = 3e-06
Identities = 64/264 (24%), Positives = 93/264 (35%), Gaps = 25/264 (9%)
Frame = +2
Query: 209 CVAPKKLLSCVNPCEIRCGDLSKKCSNVD------CIESCACPDNMLEQDGTCVQKTDCR 370
C A SC+ C C +L C C E C C +G CV +T C
Sbjct: 3893 CPAHSHFTSCLPSCPPSCANLDGSCEQTSPKVPSTCKEGCLCQPGYFLNNGKCVLQTHCD 3952
Query: 371 CTWNADLLGPKPIGYNEESLPDTIFTKDCN-NCSCRQGKWICTKNICTKDCQWSDWKIST 547
C G P G T +KDC +C+C G C C + T
Sbjct: 3953 CKDAEG--GLVPAG-------KTWTSKDCTQSCACTGGAVQCQNFQCP---------LGT 3994
Query: 548 PCNVTCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENNVAFSLKNSFCEQ 727
C + G G + + + A +G G R + C + F+ C
Sbjct: 3995 YCKDS-GDGSSNCTK-IHKGAMGDGVLMAGGIRALQ--------CPAHSHFTSCLPSCPP 4044
Query: 728 TCDDV------INKQHPTHICDEGCKCQSGYVRNSNNTCVPTSECFRCEVN------GVT 871
+C ++ N + P+ +C +GC CQ GY+ N N+ CV +C + G T
Sbjct: 4045 SCSNLDGSCVESNFKAPS-VCKKGCICQPGYLLN-NDKCVLRIQCGCKDTQGGLIPAGRT 4102
Query: 872 WQNGQTKKD------VYACRLFIC 925
W + K + CR F C
Sbjct: 4103 WISSDCTKSCSCMGGIIQCRDFQC 4126
Score = 50.8 bits (120), Expect = 5e-06
Identities = 68/279 (24%), Positives = 94/279 (33%), Gaps = 8/279 (2%)
Frame = +2
Query: 32 TYQTSECIKECSVNDSQCDPSCGNGMVTKTPQEVIKAVN--GGKDCDVIYEPCFLGNCST 205
T+ + C + C+ + C N + P E N G C I C T
Sbjct: 3370 TWTSKGCTQSCACVEGNIQ--CQN---FQCPPETYCKDNSEGSSTCTKITLQCPAHTQYT 3424
Query: 206 ACVAPKKLLSCVNPCEIRCGDLSKKCSNVDCIESCACPDNMLEQDGTCVQKTDCRCTWNA 385
+C+ P L SC++P E C D+S K + C E C C + CV + +C C
Sbjct: 3425 SCL-PSCLPSCLDP-EGLCKDISPKVPST-CKEGCVCQSGYVLNSDKCVLRAECDC---- 3477
Query: 386 DLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGK-WICTKNICTKDCQWSDWKISTPCNVT 562
KD GK W T CT+ C
Sbjct: 3478 ---------------------KDAQGALIPAGKTW--TSPGCTQSC-------------A 3501
Query: 563 CGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENNVAFSLKNSFCEQTC--- 733
C G + + Y C+ + C T C + F+ C +C
Sbjct: 3502 CMGGAVQCQSSQCPPGTY----CKDNEDGNSNCAKITLQCPAHSLFTNCLPPCLPSCLDP 3557
Query: 734 DDVINKQHPT--HICDEGCKCQSGYVRNSNNTCVPTSEC 844
D + P C EGC CQSGYV SNN C+ + C
Sbjct: 3558 DGLCKGASPKVPSTCKEGCICQSGYVL-SNNKCLLRNRC 3595
Score = 48.9 bits (115), Expect = 2e-05
Identities = 21/55 (38%), Positives = 31/55 (56%)
Frame = +2
Query: 680 CENNVAFSLKNSFCEQTCDDVINKQHPTHICDEGCKCQSGYVRNSNNTCVPTSEC 844
C N +SL C +TC + QH + C EGC+C G++ S + CVP+S+C
Sbjct: 1555 CPKNSRYSLCAKPCPETCHPISTTQHCSDKCVEGCECDPGFIL-SGSECVPSSQC 1608
Score = 48.1 bits (113), Expect = 3e-05
Identities = 64/298 (21%), Positives = 92/298 (30%), Gaps = 12/298 (4%)
Frame = +2
Query: 32 TYQTSECIKECSVNDSQCDPSCGNGMVT-KTPQEVIKAVNGGKDCDVIYEPCFLGNCSTA 208
T+ TS C + C+ C N KT + +K +G +C N
Sbjct: 3133 TWITSGCTQSCNCTGGAIQ--CQNFQCPLKTYCKDLK--DGSSNCT---------NIPLQ 3179
Query: 209 CVAPKKLLSCVNPCEIRCGDLSKKCSNVD------CIESCACPDNMLEQDGTCVQKTDCR 370
C A + +C+ C C D C C E C C L CV + C
Sbjct: 3180 CPAHSRYTNCLPSCPPLCLDPEGLCEGTSPKVPSTCREGCICQPGYLMHKNKCVLRIFCG 3239
Query: 371 C--TWNADLLGPKPIGYNEESLPDTIFTKDC-NNCSCRQGKWICTKNICTKDCQWSDWKI 541
C T A + K T ++ C +C+C G C C
Sbjct: 3240 CKNTQGAFISADK-----------TWISRGCTQSCTCPAGAIHCRNFKCP---------- 3278
Query: 542 STPCNVTCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENNVAFSLKNSFC 721
G C+ + C T C N F+ C
Sbjct: 3279 -------------------------SGTYCKNGDNGSSNCTEITLQCPTNSQFTDCLPSC 3313
Query: 722 EQTCDDVINKQHPT--HICDEGCKCQSGYVRNSNNTCVPTSECFRCEVNGVTWQNGQT 889
+C + P+ C EGC C G+V S + CVP ++C + G G+T
Sbjct: 3314 VPSCSNRCEVTSPSVPSSCREGCLCNHGFV-FSEDKCVPRTQCGCKDARGAIIPAGKT 3370
Score = 47.8 bits (112), Expect = 4e-05
Identities = 61/254 (24%), Positives = 84/254 (33%), Gaps = 13/254 (5%)
Frame = +2
Query: 158 DCDVIYEPCFLGNCSTACVAPKKLLSCVNPCEIRCGDLSKKCSNVDCIESCAC-PDNMLE 334
+C I C + T C+ P LLSC +P + C S + + C E C C PD +L
Sbjct: 2692 NCTEIILQCPDHSLYTHCL-PSCLLSCSDPDGL-CRGTSPEAPST-CKEGCVCDPDYVLS 2748
Query: 335 QDGTCVQKTDCRCTWNADLLGPKPIGYNEESLPDTIFTKDCN-NCSCRQGKWICTKNICT 511
D CV + +C C +L P T + C +CSC G C C
Sbjct: 2749 ND-KCVLRIECGCKDAQGVLIPAG---------KTWINRGCTQSCSCMGGAIQCQNFKCP 2798
Query: 512 KDCQWSDWKISTPCNVTCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENN 691
+ CQ C + C +
Sbjct: 2799 SEAY-----------------------------------CQDMEDGNSNCTSIPLQCPAH 2823
Query: 692 VAFSLKNSFCEQTCDDVI-----NKQHPTHICDEGCKCQSGYVRNSNNTCVPTSECFRCE 856
++ C+ +C D + C EGC C+ YV NN CVP EC +
Sbjct: 2824 SHYTNCLPTCQPSCSDPDGHCEGSSTKAPSACKEGCVCEPDYVM-LNNKCVPRIECGCKD 2882
Query: 857 VNGV------TWQN 880
GV TW N
Sbjct: 2883 TQGVLIPADKTWIN 2896
Score = 46.6 bits (109), Expect = 1e-04
Identities = 65/295 (22%), Positives = 98/295 (33%), Gaps = 9/295 (3%)
Frame = +2
Query: 32 TYQTSECIKECSVNDS--QCDPS-CGNGMVTKTPQEVIKAVNGGKDCDVIYEPCFLGNCS 202
T+ + C + C+ QC S C G K ++ G +C I C +
Sbjct: 3490 TWTSPGCTQSCACMGGAVQCQSSQCPPGTYCKDNED------GNSNCAKITLQCPAHSLF 3543
Query: 203 TACVAPKKLLSCVNPCEIRCGDLSKKCSNVDCIESCACPDNMLEQDGTCVQKTDCRCTWN 382
T C+ P L SC++P + C S K + C E C C + + C+ + C C
Sbjct: 3544 TNCLPPC-LPSCLDPDGL-CKGASPKVPST-CKEGCICQSGYVLSNNKCLLRNRCGC--- 3597
Query: 383 ADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGK-WICTKNICTKDCQWSDWKISTPCNV 559
KD + + K W+ CT+ C V
Sbjct: 3598 ----------------------KDAHGALIPEDKTWV--SRGCTQSC------------V 3621
Query: 560 TCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENNVAFSLKNSFCEQTCDD 739
G IQ L G C+ + C C N ++ C +C D
Sbjct: 3622 CTGGSIQCLSSQCP-----PGAYCKDNEDGSSNCARIPPQCPANSHYTDCFPPCPPSCSD 3676
Query: 740 -----VINKQHPTHICDEGCKCQSGYVRNSNNTCVPTSECFRCEVNGVTWQNGQT 889
+ C EGC C G+V + + CVP EC + G +G+T
Sbjct: 3677 PEGHCEASGPRVLSTCREGCLCNPGFVLD-RDKCVPRVECGCKDAQGALIPSGKT 3730
Score = 46.2 bits (108), Expect = 1e-04
Identities = 63/293 (21%), Positives = 90/293 (30%), Gaps = 22/293 (7%)
Frame = +2
Query: 32 TYQTSECIKECSVNDS--QCDP-SCGNGMVTKTPQEVIKAVNGGKDCDVIYEPCFLGNCS 202
T+ + +C + C+ QC C G K + G +C I++
Sbjct: 3966 TWTSKDCTQSCACTGGAVQCQNFQCPLGTYCKDSGD------GSSNCTKIHKGAMGDGVL 4019
Query: 203 TA-------CVAPKKLLSCVNPCEIRCGDLSKKCSNVD------CIESCACPDNMLEQDG 343
A C A SC+ C C +L C + C + C C L +
Sbjct: 4020 MAGGIRALQCPAHSHFTSCLPSCPPSCSNLDGSCVESNFKAPSVCKKGCICQPGYLLNND 4079
Query: 344 TCVQKTDCRCTWNADLLGPKPIGYNEESLPDTIFTKDCN-NCSCRQGKWICTKNICTKDC 520
CV + C C G P G T + DC +CSC G C C
Sbjct: 4080 KCVLRIQCGCKDTQG--GLIPAGR-------TWISSDCTKSCSCMGGIIQCRDFQCPP-- 4128
Query: 521 QWSDWKISTPCNVTCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENNVAF 700
G C+ SN + C C + +
Sbjct: 4129 ---------------------------------GTYCKESNDSSRTCAKIPLQCPAHSHY 4155
Query: 701 SLKNSFCEQTCDDVINKQHPTHI-----CDEGCKCQSGYVRNSNNTCVPTSEC 844
+ C ++C D+ T C EGC CQ GYV + N+ CV C
Sbjct: 4156 TNCLPACSRSCTDLDGHCEGTSPKVPSPCKEGCLCQPGYVVH-NHKCVLQIHC 4207
Score = 45.4 bits (106), Expect = 2e-04
Identities = 53/245 (21%), Positives = 74/245 (30%), Gaps = 13/245 (5%)
Frame = +2
Query: 194 NCSTACVAPKKLLSCVNPCEIRCGDLSKKCSNVD------CIESCACPDNMLEQDGTCVQ 355
N + C A +C+ PC+ C D C C E C C + + + CV
Sbjct: 2575 NITLQCPAHSSFTNCLPPCQPSCSDPEGHCGGSTTKAPSACQEGCVCEPDYVVLNNKCVP 2634
Query: 356 KTDCRCTWNADLLGPKPIGYNEESLPDTIF-TKDC-NNCSCRQGKWICTKNICTKDCQWS 529
+ +C C +L P D I+ K C C+C G C C
Sbjct: 2635 RIECGCKDAQGVLIP----------ADKIWINKGCTQTCACVTGTIHCRDFQCP------ 2678
Query: 530 DWKISTPCNVTCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENNVAFSLK 709
G C+ C C ++ ++
Sbjct: 2679 -----------------------------SGTYCKDIKDDASNCTEIILQCPDHSLYTHC 2709
Query: 710 NSFCEQTCDDVINKQHPT-----HICDEGCKCQSGYVRNSNNTCVPTSECFRCEVNGVTW 874
C +C D T C EGC C YV SN+ CV EC + GV
Sbjct: 2710 LPSCLLSCSDPDGLCRGTSPEAPSTCKEGCVCDPDYVL-SNDKCVLRIECGCKDAQGVLI 2768
Query: 875 QNGQT 889
G+T
Sbjct: 2769 PAGKT 2773
Score = 45.4 bits (106), Expect = 2e-04
Identities = 70/291 (24%), Positives = 93/291 (31%), Gaps = 20/291 (6%)
Frame = +2
Query: 32 TYQTSECIKECSVNDS--QC-DPSCGNGMVTKTPQEVIKAVNGGKDCDVIYEPCFLGNCS 202
T+ +S+C K CS QC D C G K + + C I
Sbjct: 4102 TWISSDCTKSCSCMGGIIQCRDFQCPPGTYCKESND------SSRTCAKI---------P 4146
Query: 203 TACVAPKKLLSCVNPCEIRCGDLSKKCSNVD------CIESCACPDNMLEQDGTCVQKTD 364
C A +C+ C C DL C C E C C + + CV +
Sbjct: 4147 LQCPAHSHYTNCLPACSRSCTDLDGHCEGTSPKVPSPCKEGCLCQPGYVVHNHKCVLQIH 4206
Query: 365 CRCTWNADLLGPKPIGYNEESLPDTIFTKDC-NNCSCRQGKWICTKNICT--KDCQWSDW 535
C C G P G T ++ C +C+C G C C CQ S
Sbjct: 4207 CGCKDAQG--GFVPAG-------KTWISRGCTQSCACVGGAVQCHNFTCPTGTQCQNSSC 4257
Query: 536 -KISTPCNVTCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENNVAFSLK- 709
KI+ C Q L + EG S R C C + V K
Sbjct: 4258 SKITVQCPAH-SQYTTCLPSCLPSCFDPEGLCGGASPRAPSTCREGCVCEADYVLREDKC 4316
Query: 710 ----NSFCEQTCDDVI--NKQHPTHICDEGCKCQSGYVRNSNNTCVPTSEC 844
C+ D+I NK T C + C C+ G + N C +EC
Sbjct: 4317 VLRTQCGCKDAQGDLIPANKTWLTRGCAQKCTCKGGNIHCWNFKCPLGTEC 4367
Score = 44.7 bits (104), Expect = 4e-04
Identities = 55/241 (22%), Positives = 78/241 (32%), Gaps = 14/241 (5%)
Frame = +2
Query: 209 CVAPKKLLSCVNPCEIRCGDLSKKCSNVD------CIESCAC-PDNMLEQDGTCVQKTDC 367
C A C PC C D C C E C C P +L++D CV + +C
Sbjct: 3657 CPANSHYTDCFPPCPPSCSDPEGHCEASGPRVLSTCREGCLCNPGFVLDRD-KCVPRVEC 3715
Query: 368 RCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGK-WICTKNICTKDCQWSDWKIS 544
C KD GK W T CT+ C
Sbjct: 3716 GC-------------------------KDAQGALIPSGKTW--TSPGCTQSC-------- 3740
Query: 545 TPCNVTCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENNVAFSLKNSFCE 724
C G+ + + Y C+ + C T C + ++ FC
Sbjct: 3741 -----ACMGGVVQCQSSQCPPGTY----CKDNEDGNSNCAKITLQCPTHSNYTDCLPFCL 3791
Query: 725 QTCDDV------INKQHPTHICDEGCKCQSGYVRNSNNTCVPTSECFRCEVNGVTWQNGQ 886
+C D + + P+ C EGC CQ GYV + + C+ EC + G G+
Sbjct: 3792 PSCLDPSALCGGTSPKGPS-TCKEGCVCQPGYVLDKDK-CILKIECGCRDTQGAVIPAGK 3849
Query: 887 T 889
T
Sbjct: 3850 T 3850
Score = 42.0 bits (97), Expect = 0.002
Identities = 31/108 (28%), Positives = 45/108 (41%), Gaps = 3/108 (2%)
Frame = +2
Query: 194 NCSTACVAPKKLLSCVNPCEIRCGD-LSKKCSNVDCIESCACPDNMLEQDGTCVQKTDCR 370
+C+ C A C+ PC C ++ K C+E CA + D + T C
Sbjct: 5145 HCAMTCPANTVYQRCMTPCPASCAKFVTPKVCEGPCVEGCASLPGYIYSDTQSLPVTHCG 5204
Query: 371 CTWNADLLGPKPIGYNEESLPDTIFTKDCN-NCSC-RQGKWICTKNIC 508
CT AD + K L D+ T DC+ +C+C QG +C C
Sbjct: 5205 CT--ADGIYYK--------LGDSFVTNDCSQHCTCASQGILLCEPYGC 5242
Score = 41.6 bits (96), Expect = 0.003
Identities = 49/223 (21%), Positives = 68/223 (30%), Gaps = 11/223 (4%)
Frame = +2
Query: 194 NC---STACVAPKKLLSCVNPCEIRCGDLSKKCSNVD------CIESCACPDNMLEQDGT 346
NC S C A SC+ C+ C + C C E C C + +
Sbjct: 3052 NCTRISLQCPANSNFTSCLPSCQPSCSNTDVHCEGSSPNTLSSCREGCVCQSGYVLHNDK 3111
Query: 347 CVQKTDCRCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGK-WICTKNICTKDCQ 523
C+ + C C KD +GK WI + CT+ C
Sbjct: 3112 CILRNQCGC-------------------------KDAQGALIPEGKTWITSG--CTQSCN 3144
Query: 524 WSDWKISTPCNVTCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENNVAFS 703
+ I Q Q +T + + +C T C +
Sbjct: 3145 CTGGAIQC-------QNFQCPLKTYCKDLKDGSSNCTNIPLQCPAHSRYTNCLPSCPPLC 3197
Query: 704 LK-NSFCEQTCDDVINKQHPTHICDEGCKCQSGYVRNSNNTCV 829
L CE T V + C EGC CQ GY+ + N CV
Sbjct: 3198 LDPEGLCEGTSPKVPST------CREGCICQPGYLMHKNK-CV 3233
Score = 40.0 bits (92), Expect = 0.009
Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 2/69 (2%)
Frame = +2
Query: 176 EPCFLGNCSTACVAPKKLLSCVNPCEIRCGDLS--KKCSNVDCIESCACPDNMLEQDGTC 349
EP F C C + C PC C +S + CS+ C+E C C + C
Sbjct: 1547 EPQF---CPLVCPKNSRYSLCAKPCPETCHPISTTQHCSD-KCVEGCECDPGFILSGSEC 1602
Query: 350 VQKTDCRCT 376
V + C CT
Sbjct: 1603 VPSSQCGCT 1611
Score = 39.7 bits (91), Expect = 0.012
Identities = 18/62 (29%), Positives = 23/62 (37%), Gaps = 2/62 (3%)
Frame = +2
Query: 197 CSTACVAPKKLLSCVNPCEIRCGDLS--KKCSNVDCIESCACPDNMLEQDGTCVQKTDCR 370
C C C N C C LS + C + C+E C C + TCV C
Sbjct: 1937 CPMRCPPRSSYNPCANSCPATCLTLSTPRDCPTLPCVEGCECQSGHILSGTTCVPLRQCG 1996
Query: 371 CT 376
C+
Sbjct: 1997 CS 1998
Score = 38.5 bits (88), Expect = 0.027
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Frame = +2
Query: 719 CEQTCDDVINKQH-PTHICDEGCKCQSGYVRNSNNTCVPTSEC 844
C TC + + PT C EGC+CQSG++ S TCVP +C
Sbjct: 1954 CPATCLTLSTPRDCPTLPCVEGCECQSGHIL-SGTTCVPLRQC 1995
Score = 35.0 bits (79), Expect = 0.30
Identities = 30/127 (23%), Positives = 43/127 (33%), Gaps = 2/127 (1%)
Frame = +2
Query: 197 CSTACVAPKKLLSCVNPCEIRCGDLSKKCSNVDCIESCACPDNMLEQDGTCVQKTDCRCT 376
C +C +PK SC PC I C C L + C+ ++ C C
Sbjct: 1182 CPASCESPKP--SCQPPC----------------IPGCVCNPGFLFSNNQCINESSCNCP 1223
Query: 377 WNADLLGPKPIGYNEESLP-DTIFTKDC-NNCSCRQGKWICTKNICTKDCQWSDWKISTP 550
+N N+ P + FT +C C C G + +CQ S T
Sbjct: 1224 YN-----------NKHYKPGEEWFTPNCTERCRCLPGSLM--------ECQISQCGTHTV 1264
Query: 551 CNVTCGQ 571
C + Q
Sbjct: 1265 CQLKSDQ 1271
>sp|Q62635|MUC2_RAT Mucin-2 precursor (Intestinal mucin 2)
Length = 1513
Score = 60.8 bits (146), Expect = 5e-09
Identities = 35/114 (30%), Positives = 54/114 (47%), Gaps = 10/114 (8%)
Frame = +2
Query: 209 CVAPKKLLSCVN--------PCEIRCGDLSKKCSNVDCIESCACPDNMLEQD-GTCVQKT 361
C++P+ L+ C N P C L + + +CI C CPD +L+ G CV +
Sbjct: 756 CLSPQILVDCNNLTALAIREPRPTSCQTLVARYYHTECISGCVCPDGLLDNGRGGCVVED 815
Query: 362 DCRCTWNADLLGPKPIGYNEESLPDTIFTKDCNN-CSCRQGKWICTKNICTKDC 520
+C C N K + +S+ DCNN C+C++G+W CT+ C C
Sbjct: 816 ECPCIHN------KQFYDSGKSIK-----LDCNNTCTCQKGRWECTRYACHSTC 858
Score = 45.8 bits (107), Expect = 2e-04
Identities = 32/120 (26%), Positives = 45/120 (37%), Gaps = 11/120 (9%)
Frame = +2
Query: 194 NCSTACVAPKKL------LSCVNPCEIRCGDL--SKKCSNVDCIESCACPDNMLEQDGT- 346
N TA + PKK L +P C L S C ++ C CP+ + D T
Sbjct: 281 NWRTASLCPKKCPGNMVYLESGSPWLDTCSHLEVSSLCEE-HYMDGCFCPEGTVYDDITG 339
Query: 347 --CVQKTDCRCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGKWICTKNICTKDC 520
C+ + C C + L +P T DC C C G+W+C C + C
Sbjct: 340 SGCIPVSQCHCKLHGHLY-----------MPGQEITNDCEQCVCNAGRWMCKDLPCPETC 388
Score = 38.9 bits (89), Expect = 0.021
Identities = 45/237 (18%), Positives = 79/237 (33%), Gaps = 7/237 (2%)
Frame = +2
Query: 206 ACVAPKKLLSCVNPCEIRCGDLSKKCSNVDC------IESCACPDN-MLEQDGTCVQKTD 364
AC + + + + C+ C +S+ + C +E C CPD+ +++ G CV +
Sbjct: 657 ACPSSQIFMYNLTTCQQTCRSISE--GDTHCLKGFAPVEGCGCPDHTFMDEKGRCVPLSK 714
Query: 365 CRCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGKWICTKNICTKDCQWSDWKIS 544
C C + L + +E C CR G+ CT+
Sbjct: 715 CSCYHHGLYLEAGDVILRQEE-----------RCICRNGRLQCTQ--------------- 748
Query: 545 TPCNVTCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCYAATKCCENNVAFSLKNSFCE 724
+ G C + C N A +++
Sbjct: 749 ---------------------VKLIGHTCLSPQILVD--------CNNLTALAIREPR-P 778
Query: 725 QTCDDVINKQHPTHICDEGCKCQSGYVRNSNNTCVPTSECFRCEVNGVTWQNGQTKK 895
+C ++ + + T C GC C G + N CV EC C N + +G++ K
Sbjct: 779 TSCQTLVARYYHTE-CISGCVCPDGLLDNGRGGCVVEDEC-PCIHNKQFYDSGKSIK 833
Score = 35.8 bits (81), Expect = 0.18
Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 5/83 (6%)
Frame = +2
Query: 650 EEMCYAATKCCENNVAFSLKNSFCEQTCDDVINKQHPTHICD-----EGCKCQSGYVRNS 814
E +C C ++ F + C+QTC + + TH EGC C +
Sbjct: 648 ESVCNKDVHACPSSQIFMYNLTTCQQTCRSI--SEGDTHCLKGFAPVEGCGCPDHTFMDE 705
Query: 815 NNTCVPTSECFRCEVNGVTWQNG 883
CVP S+C C +G+ + G
Sbjct: 706 KGRCVPLSKC-SCYHHGLYLEAG 727
>sp|P98167|SSPO_BOVIN SCO-spondin
Length = 867
Score = 53.5 bits (127), Expect = 8e-07
Identities = 60/250 (24%), Positives = 87/250 (34%), Gaps = 27/250 (10%)
Frame = +2
Query: 17 NCKALTYQTSECIKECSVND---------SQCDPSCGNGMVTKTPQEVIKAVNGGKDCDV 169
+C QT C D S C CG VT +E NGG+ C
Sbjct: 10 HCPGPERQTRACFAAACPEDGVWTSWSRWSPCSEPCGG--VTARHRECHPPQNGGRTCAT 67
Query: 170 I---------YEPCFLGNCSTACVAPKKLLSCVNPCEIRCGDLSKKCS---NVDCI-ESC 310
+ PC C + + + PC + C D+S + + + C C
Sbjct: 68 LPGGPPSTRETRPCPQDGCPNVTCSGELVFHACVPCPLTCDDISGQATCPPDRPCGGPGC 127
Query: 311 ACP-DNMLEQDGTCVQKTDCRCTWNADLLGPKPIGYNEESLPDTIFTKDCNNCSCRQGK- 484
CP +L G CV C C + P G ++ DC C C+ G+
Sbjct: 128 WCPAGQVLGAQGRCVWPRQCPCLVDGSRYWP---GQRVKT--------DCQLCVCQDGRP 176
Query: 485 WICTKNI-CTKDCQWSDWKISTPCNVTCG-QGIQILERTVARVAQY-EGKDCQGSNRTEE 655
C ++ C +C WS W C CG + +Q R+ G C+G +R
Sbjct: 177 RRCQPSLDCAVNCGWSAWSPWAECLGPCGSRSVQWSFRSPNNPRPAGRGHQCRGLHRKAR 236
Query: 656 MCYAATKCCE 685
C T+ CE
Sbjct: 237 RC--QTEPCE 244
Score = 48.1 bits (113), Expect = 3e-05
Identities = 46/157 (29%), Positives = 62/157 (39%), Gaps = 12/157 (7%)
Frame = +2
Query: 491 CTKNICTKDCQWSDWKISTPCNVTCGQGIQILERTVARVAQYEGKDCQ----GSNRTEEM 658
C C +D W+ W +PC+ CG G+ R Q G+ C G T E
Sbjct: 21 CFAAACPEDGVWTSWSRWSPCSEPCG-GVTARHRE-CHPPQNGGRTCATLPGGPPSTRET 78
Query: 659 CYAATKCCENNVAFSLKNSF-----CEQTCDDVINKQ--HPTHIC-DEGCKCQSGYVRNS 814
C NV S + F C TCDD+ + P C GC C +G V +
Sbjct: 79 RPCPQDGCP-NVTCSGELVFHACVPCPLTCDDISGQATCPPDRPCGGPGCWCPAGQVLGA 137
Query: 815 NNTCVPTSECFRCEVNGVTWQNGQTKKDVYACRLFIC 925
CV +C C V+G + GQ K C+L +C
Sbjct: 138 QGRCVWPRQC-PCLVDGSRYWPGQRVKT--DCQLCVC 171
Score = 31.2 bits (69), Expect = 4.3
Identities = 33/158 (20%), Positives = 57/158 (36%), Gaps = 21/158 (13%)
Frame = +2
Query: 254 IRCGDLSKKCSNVDCIESCACPDNMLEQDGTCVQKTDCR-CTWNADLLGPKPIGYNEESL 430
++C C + C+E + + + C+ +D R C W A G P +L
Sbjct: 663 VQCSPGQVPCEVLGCVEL----EQLCDGREDCLDGSDERPCAWAA---GTVPFTVPTTTL 715
Query: 431 PDTIFTKDC---NNCSCRQGKWICTKNICTK--DCQ---------------WSDWKISTP 550
P ++D + +C G+ + + C DCQ WS W +
Sbjct: 716 PGLPASRDLCSPSQLTCGSGECLPVERRCDLQLDCQDGSDENGCVDCGLAPWSGW---SS 772
Query: 551 CNVTCGQGIQILERTVARVAQYEGKDCQGSNRTEEMCY 664
C+ +CG G+ R + R G C + C+
Sbjct: 773 CSRSCGLGLAFQRRELLR-PPLPGGSCPPDRLRSQPCF 809
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 113,819,584
Number of Sequences: 369166
Number of extensions: 2581081
Number of successful extensions: 9107
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7338
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8804
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9510757740
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)