Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_A23
(776 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P29190|PPCK_HAECO Phosphoenolpyruvate carboxykinase [GTP... 286 4e-77
sp|Q05893|PPCK_ASCSU Phosphoenolpyruvate carboxykinase [GTP... 274 2e-73
sp|Q16822|PPCKM_HUMAN Phosphoenolpyruvate carboxykinase, mi... 267 2e-71
sp|Q8BH04|PPCKM_MOUSE Phosphoenolpyruvate carboxykinase, mi... 267 3e-71
sp|P20007|PPCK_DROME Phosphoenolpyruvate carboxykinase [GTP... 253 4e-67
sp|P07379|PPCKC_RAT Phosphoenolpyruvate carboxykinase, cyto... 251 1e-66
sp|Q9Z2V4|PPCKC_MOUSE Phosphoenolpyruvate carboxykinase, cy... 250 3e-66
sp|P05153|PPCKC_CHICK Phosphoenolpyruvate carboxykinase, cy... 239 6e-63
sp|P35558|PPCKC_HUMAN Phosphoenolpyruvate carboxykinase, cy... 239 8e-63
sp|Q5R5J1|PPCKC_PONPY Phosphoenolpyruvate carboxykinase, cy... 239 8e-63
>sp|P29190|PPCK_HAECO Phosphoenolpyruvate carboxykinase [GTP] (Phosphoenolpyruvate
carboxylase) (PEPCK)
Length = 619
Score = 286 bits (732), Expect = 4e-77
Identities = 130/206 (63%), Positives = 161/206 (78%), Gaps = 2/206 (0%)
Frame = -3
Query: 750 IIHPKWEDPKGVPISAIVFGGRRPEGIPLIMQAFNWKHGVMLGASLKSEATAAAEFKGKQ 571
IIHP+WE PKGVPI AI+FGGRRP G+PL+ + +W HG+ GA LKSEATAAAE KGK
Sbjct: 411 IIHPEWESPKGVPIDAIIFGGRRPAGVPLVFETRSWLHGIFTGACLKSEATAAAEHKGKT 470
Query: 570 IMHDPMAMRPFMGYNFGKYLQHWLDLEKPGRKMPLIFHVNWFRLNDKGKFVWPGFGENIR 391
+MHDPMAMRPFMGYNFG YLQHW+DL K GRK+P I+HVNWFR + KF+WPG+G+NIR
Sbjct: 471 VMHDPMAMRPFMGYNFGHYLQHWIDLNKDGRKVPKIYHVNWFRRDANNKFLWPGYGQNIR 530
Query: 390 VIDWMCRRVNGE-DIAEPSPIGLLPKHGTINVTGL-DAKWDEMFSLPKAYLSEDVQETMK 217
VIDW+ RR++GE DI +PIG++PK G IN +GL D +WDE+ S+PK Y + D +E K
Sbjct: 531 VIDWIVRRLDGEPDIGVDTPIGIVPKKGAINASGLPDIQWDELMSVPKEYWTNDAKEIRK 590
Query: 216 FLREQTGEDLPAGIIQELNEQEKRIH 139
FL EQ G DLP I E++ QE+RI+
Sbjct: 591 FLEEQVGPDLPKEIRAEMDAQEERIN 616
>sp|Q05893|PPCK_ASCSU Phosphoenolpyruvate carboxykinase [GTP] (Phosphoenolpyruvate
carboxylase) (PEPCK)
Length = 643
Score = 274 bits (700), Expect = 2e-73
Identities = 124/205 (60%), Positives = 158/205 (77%), Gaps = 2/205 (0%)
Frame = -3
Query: 750 IIHPKWEDPKGVPISAIVFGGRRPEGIPLIMQAFNWKHGVMLGASLKSEATAAAEFKGKQ 571
IIHP WE P+GVPI AI+FGGRRPEG+PL+ ++ +W HG+ +GA +KSEATAAAE GKQ
Sbjct: 434 IIHPDWEKPEGVPIDAIIFGGRRPEGVPLVFESRSWVHGIFVGACVKSEATAAAEHTGKQ 493
Query: 570 IMHDPMAMRPFMGYNFGKYLQHWLDLEKPGRKMPLIFHVNWFRLNDKGKFVWPGFGENIR 391
+MHDPMAMRPFMGYNFG+Y++HW+ L +P K+P IFHVNWFR + KF+WPG+G+NIR
Sbjct: 494 VMHDPMAMRPFMGYNFGRYMRHWMKLGQPPHKVPKIFHVNWFRQSADHKFLWPGYGDNIR 553
Query: 390 VIDWMCRRVNGE-DIAEPSPIGLLPKHGTINVTGL-DAKWDEMFSLPKAYLSEDVQETMK 217
VIDW+ RR +G+ IAE +PIG +PK GTIN+ GL + WDE+ S+PK+Y ED+ ET
Sbjct: 554 VIDWILRRCSGDATIAEETPIGFIPKKGTINLEGLPNVNWDELMSIPKSYWLEDMVETKT 613
Query: 216 FLREQTGEDLPAGIIQELNEQEKRI 142
F Q G DLP I +EL Q +RI
Sbjct: 614 FFENQVGSDLPPEIAKELEAQTERI 638
>sp|Q16822|PPCKM_HUMAN Phosphoenolpyruvate carboxykinase, mitochondrial precursor [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-M)
Length = 640
Score = 267 bits (683), Expect = 2e-71
Identities = 117/208 (56%), Positives = 160/208 (76%), Gaps = 2/208 (0%)
Frame = -3
Query: 750 IIHPKWEDPKGVPISAIVFGGRRPEGIPLIMQAFNWKHGVMLGASLKSEATAAAEFKGKQ 571
I+ P WE P+GVPI AI+FGGRRP+G+PL+ +AFNW+HGV +G +++SE+TAAAE KGK
Sbjct: 433 IMDPAWEAPEGVPIDAIIFGGRRPKGVPLVYEAFNWRHGVFVGRAMRSESTAAAEHKGKI 492
Query: 570 IMHDPMAMRPFMGYNFGKYLQHWLDLE-KPGRKMPLIFHVNWFRLNDKGKFVWPGFGENI 394
IMHDP AMRPF GYNFG YL+HWL +E + G ++P IFHVNWFR ++ G F+WPGFGEN
Sbjct: 493 IMHDPFAMRPFFGYNFGHYLEHWLSMEGRKGAQLPRIFHVNWFRRDEAGHFLWPGFGENA 552
Query: 393 RVIDWMCRRVNGEDIAEPSPIGLLPKHGTINVTGLDA-KWDEMFSLPKAYLSEDVQETMK 217
RV+DW+CRR+ GED A +PIGL+PK G ++++GL A ++FSLPK + ++V++
Sbjct: 553 RVLDWICRRLEGEDSARETPIGLVPKEGALDLSGLRAIDTTQLFSLPKDFWEQEVRDIRS 612
Query: 216 FLREQTGEDLPAGIIQELNEQEKRIHNM 133
+L EQ +DLP ++ EL E+R+H M
Sbjct: 613 YLTEQVNQDLPKEVLAELEALERRVHKM 640
>sp|Q8BH04|PPCKM_MOUSE Phosphoenolpyruvate carboxykinase, mitochondrial precursor [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-M)
Length = 640
Score = 267 bits (682), Expect = 3e-71
Identities = 115/208 (55%), Positives = 162/208 (77%), Gaps = 2/208 (0%)
Frame = -3
Query: 750 IIHPKWEDPKGVPISAIVFGGRRPEGIPLIMQAFNWKHGVMLGASLKSEATAAAEFKGKQ 571
I+ P WE P+GVPI AI+FGGRRP+G+PL+ +AFNW+HGV +G++++SE+TAAAE KGK
Sbjct: 433 IMDPAWEAPEGVPIDAIIFGGRRPKGVPLVYEAFNWRHGVFVGSAMRSESTAAAEHKGKT 492
Query: 570 IMHDPMAMRPFMGYNFGKYLQHWLDLE-KPGRKMPLIFHVNWFRLNDKGKFVWPGFGENI 394
IMHDP AMRPF GYNFG+YL+HWL +E + G ++P IFHVNWFR ++ G+F+WPGFGEN
Sbjct: 493 IMHDPFAMRPFFGYNFGRYLEHWLSMEGQKGARLPRIFHVNWFRRDEAGRFLWPGFGENA 552
Query: 393 RVIDWMCRRVNGEDIAEPSPIGLLPKHGTINVTGLDA-KWDEMFSLPKAYLSEDVQETMK 217
RV+DW+CRR+ GED A+ +PIGL+PK G ++++GL A ++FS+PK + ++V++
Sbjct: 553 RVLDWICRRLEGEDSAQETPIGLVPKEGALDLSGLSAVDTSQLFSIPKDFWEQEVRDIRG 612
Query: 216 FLREQTGEDLPAGIIQELNEQEKRIHNM 133
+L EQ +DLP ++ EL E R+ M
Sbjct: 613 YLTEQVNQDLPKEVLAELEALEGRVQKM 640
>sp|P20007|PPCK_DROME Phosphoenolpyruvate carboxykinase [GTP] (Phosphoenolpyruvate
carboxylase) (PEPCK)
Length = 647
Score = 253 bits (646), Expect = 4e-67
Identities = 118/208 (56%), Positives = 153/208 (73%), Gaps = 2/208 (0%)
Frame = -3
Query: 750 IIHPKWEDPKGVPISAIVFGGRRPEGIPLIMQAFNWKHGVMLGASLKSEATAAAEFKGKQ 571
II WEDP GVPISA++FGGRRP G+PLI +A +W HGV +GA+++SEATAAAE KGK
Sbjct: 441 IIDEAWEDPAGVPISAMLFGGRRPAGVPLIYEARDWTHGVFIGAAMRSEATAAAEHKGKV 500
Query: 570 IMHDPMAMRPFMGYNFGKYLQHWLDLEKPGRKMPLIFHVNWFRLNDKGKFVWPGFGENIR 391
IMHDP AMRPF GYNFG Y+ HWL +EK G ++P IFHVNWFR + +GKF+WPG+GEN R
Sbjct: 501 IMHDPFAMRPFFGYNFGDYVAHWLSMEKRG-QVPKIFHVNWFRKSAEGKFMWPGYGENSR 559
Query: 390 VIDWMCRRVNGEDIAEPSPIGLLPKHGTINVTGLDAKWD--EMFSLPKAYLSEDVQETMK 217
V++W+ RRVNGE S IG +P G +N+ G+ K D E+FSLPK + S++V++
Sbjct: 560 VLEWILRRVNGESCYVDSAIGHIPAEGALNLDGMKDKVDVKEIFSLPKEFWSQEVKDIRT 619
Query: 216 FLREQTGEDLPAGIIQELNEQEKRIHNM 133
+ Q G DLPA I Q+L+E R+ N+
Sbjct: 620 YFESQVGADLPASIYQQLDELSSRVDNL 647
>sp|P07379|PPCKC_RAT Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 251 bits (642), Expect = 1e-66
Identities = 115/208 (55%), Positives = 151/208 (72%), Gaps = 2/208 (0%)
Frame = -3
Query: 750 IIHPKWEDPKGVPISAIVFGGRRPEGIPLIMQAFNWKHGVMLGASLKSEATAAAEFKGKQ 571
II P WE P+GVPI I+FGGRRP G+PL+ +A +W+HGV +GA+++SEATAAAE KGK
Sbjct: 415 IIDPAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKV 474
Query: 570 IMHDPMAMRPFMGYNFGKYLQHWLDL-EKPGRKMPLIFHVNWFRLNDKGKFVWPGFGENI 394
IMHDP AMRPF GYNFGKYL HWL + +P K+P IFHVNWFR + GKF+WPGFGEN
Sbjct: 475 IMHDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPKIFHVNWFRKDKNGKFLWPGFGENS 534
Query: 393 RVIDWMCRRVNGEDIAEPSPIGLLPKHGTINVTGL-DAKWDEMFSLPKAYLSEDVQETMK 217
RV++WM R+ GED A+ +PIG +PK +N+ GL D +E+F + K + ++V+E K
Sbjct: 535 RVLEWMFGRIEGEDSAKLTPIGYVPKEDALNLKGLGDVNVEELFGISKEFWEKEVEEIDK 594
Query: 216 FLREQTGEDLPAGIIQELNEQEKRIHNM 133
+L +Q DLP I +EL ++RI M
Sbjct: 595 YLEDQVNADLPYEIERELRALKQRISQM 622
>sp|Q9Z2V4|PPCKC_MOUSE Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 250 bits (638), Expect = 3e-66
Identities = 114/208 (54%), Positives = 151/208 (72%), Gaps = 2/208 (0%)
Frame = -3
Query: 750 IIHPKWEDPKGVPISAIVFGGRRPEGIPLIMQAFNWKHGVMLGASLKSEATAAAEFKGKQ 571
II P WE P+GVPI I+FGGRRPEG+PL+ +A +W+HGV +GA+++SEATAAAE KGK
Sbjct: 415 IIDPAWESPEGVPIEGIIFGGRRPEGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKI 474
Query: 570 IMHDPMAMRPFMGYNFGKYLQHWLDL-EKPGRKMPLIFHVNWFRLNDKGKFVWPGFGENI 394
IMHDP AMRPF GYNFGKYL HWL + +P K+P IFHVNWFR + GKF+WPGFGEN
Sbjct: 475 IMHDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPKIFHVNWFRKDKDGKFLWPGFGENS 534
Query: 393 RVIDWMCRRVNGEDIAEPSPIGLLPKHGTINVTGL-DAKWDEMFSLPKAYLSEDVQETMK 217
RV++WM R+ GED A+ +PIG +PK +N+ GL +E+F + K + ++V+E +
Sbjct: 535 RVLEWMFGRIEGEDSAKLTPIGYIPKENALNLKGLGGVNVEELFGISKEFWEKEVEEIDR 594
Query: 216 FLREQTGEDLPAGIIQELNEQEKRIHNM 133
+L +Q DLP I +EL ++RI M
Sbjct: 595 YLEDQVNTDLPYEIERELRALKQRISQM 622
>sp|P05153|PPCKC_CHICK Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 239 bits (610), Expect = 6e-63
Identities = 109/208 (52%), Positives = 147/208 (70%), Gaps = 2/208 (0%)
Frame = -3
Query: 750 IIHPKWEDPKGVPISAIVFGGRRPEGIPLIMQAFNWKHGVMLGASLKSEATAAAEFKGKQ 571
I+ P WE P+GVPI I+FGGRRP G+PL+ +AFNW+HGV +GA+++SEATAAAE KGK
Sbjct: 415 IMDPAWESPEGVPIEGIIFGGRRPAGVPLVYEAFNWQHGVFIGAAMRSEATAAAEHKGKI 474
Query: 570 IMHDPMAMRPFMGYNFGKYLQHWLDL-EKPGRKMPLIFHVNWFRLNDKGKFVWPGFGENI 394
IMHDP AMRPF GYNFGKYL HWL + +P K+P IFHVNWFR + +GKF+WPG+GEN
Sbjct: 475 IMHDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPRIFHVNWFRKDSQGKFLWPGYGENS 534
Query: 393 RVIDWMCRRVNGEDIAEPSPIGLLPKHGTINVTGL-DAKWDEMFSLPKAYLSEDVQETMK 217
RV++WM R+ G+ A+ + IG +P +N+ GL D E+F++ K + ++V+E +
Sbjct: 535 RVLEWMFNRIQGKASAKSTAIGYIPADTALNLKGLEDINLTELFNISKEFWEKEVEEIKQ 594
Query: 216 FLREQTGEDLPAGIIQELNEQEKRIHNM 133
+ Q DLP I +EL E RI +
Sbjct: 595 YFEGQVNADLPYEIERELLALEMRIKQL 622
>sp|P35558|PPCKC_HUMAN Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 239 bits (609), Expect = 8e-63
Identities = 109/208 (52%), Positives = 149/208 (71%), Gaps = 2/208 (0%)
Frame = -3
Query: 750 IIHPKWEDPKGVPISAIVFGGRRPEGIPLIMQAFNWKHGVMLGASLKSEATAAAEFKGKQ 571
II WE P+GVPI I+FGGRRP G+PL+ +A +W+HGV +GA+++SEATAAAE KGK
Sbjct: 415 IIDAAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKI 474
Query: 570 IMHDPMAMRPFMGYNFGKYLQHWLDL-EKPGRKMPLIFHVNWFRLNDKGKFVWPGFGENI 394
IMHDP AMRPF GYNFGKYL HWL + + P K+P IFHVNWFR + +GKF+WPGFGEN
Sbjct: 475 IMHDPFAMRPFFGYNFGKYLAHWLSMAQHPAAKLPKIFHVNWFRKDKEGKFLWPGFGENS 534
Query: 393 RVIDWMCRRVNGEDIAEPSPIGLLPKHGTINVTGL-DAKWDEMFSLPKAYLSEDVQETMK 217
RV++WM R++G+ + +PIG +PK +N+ GL E+FS+ K + ++V++ K
Sbjct: 535 RVLEWMFNRIDGKASTKLTPIGYIPKEDALNLKGLGHINMMELFSISKEFWEKEVEDIEK 594
Query: 216 FLREQTGEDLPAGIIQELNEQEKRIHNM 133
+L +Q DLP I +E+ ++RI M
Sbjct: 595 YLEDQVNADLPCEIEREILALKQRISQM 622
>sp|Q5R5J1|PPCKC_PONPY Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 239 bits (609), Expect = 8e-63
Identities = 110/208 (52%), Positives = 150/208 (72%), Gaps = 2/208 (0%)
Frame = -3
Query: 750 IIHPKWEDPKGVPISAIVFGGRRPEGIPLIMQAFNWKHGVMLGASLKSEATAAAEFKGKQ 571
II WE P+GVPI I+FGGRRP G+PL+ +A +W+HGV +GA+++SEATAAAE KGK
Sbjct: 415 IIDAAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKI 474
Query: 570 IMHDPMAMRPFMGYNFGKYLQHWLDL-EKPGRKMPLIFHVNWFRLNDKGKFVWPGFGENI 394
IMHDP AMRPF GYNFGKYL HWL + + P K+P IFHVNWFR + +GKF+WPGFGEN
Sbjct: 475 IMHDPFAMRPFFGYNFGKYLAHWLSMAQHPAAKLPKIFHVNWFRKDKEGKFLWPGFGENS 534
Query: 393 RVIDWMCRRVNGEDIAEPSPIGLLPKHGTINVTGL-DAKWDEMFSLPKAYLSEDVQETMK 217
RV++WM R++G+ A+ +PIG +PK +N+ GL E+FS+ K + ++V++ K
Sbjct: 535 RVLEWMFNRIDGKAGAKLTPIGYIPKEDALNLKGLGHINVMELFSISKEFWEKEVEDIEK 594
Query: 216 FLREQTGEDLPAGIIQELNEQEKRIHNM 133
+L +Q DLP I +E+ ++RI M
Sbjct: 595 YLEDQVNADLPCEIEREILALKQRISQM 622
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 101,263,854
Number of Sequences: 369166
Number of extensions: 2283266
Number of successful extensions: 5966
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5665
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5889
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7260540000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)