Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_A06
(678 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P61962|WDR68_HUMAN WD-repeat protein 68 (WD-repeat prote... 338 1e-92
sp|Q9XGN1|TTG1_ARATH TRANSPARENT TESTA GLABRA 1 protein (TT... 206 5e-53
sp|O22469|MSI3_ARATH WD-40 repeat protein MSI3 51 3e-06
sp|P90916|LIN53_CAEEL Trp-Asp repeats containing protein li... 50 4e-06
sp|O22607|MSI4_ARATH WD-40 repeat protein MSI4 50 7e-06
sp|Q8CFJ9|WDR24_MOUSE WD-repeat protein 24 49 1e-05
sp|Q96S15|WDR24_HUMAN WD-repeat protein 24 48 3e-05
sp|O22468|MSI2_ARATH WD-40 repeat protein MSI2 47 4e-05
sp|Q04225|RRB1_YEAST Ribosome assembly protein RRB1 47 5e-05
sp|O14021|PRW1_SCHPO RbAp48-related WD40-repeat protein prw1 47 6e-05
>sp|P61962|WDR68_HUMAN WD-repeat protein 68 (WD-repeat protein An11 homolog)
sp|P61963|WDR68_MOUSE WD-repeat protein 68 (WD-repeat protein An11 homolog)
Length = 342
Score = 338 bits (866), Expect = 1e-92
Identities = 154/199 (77%), Positives = 174/199 (87%)
Frame = +3
Query: 3 TCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRM 182
TCTIW LETGQV+GR V+G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRM
Sbjct: 144 TCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRM 203
Query: 183 FDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLN 362
FDLRHLEHSTIIYEDP LLRL WNKQD NYLAT ++ E+++LD+RVPCTPVARLN
Sbjct: 204 FDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLN 263
Query: 363 NHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSS 542
NHR CVNG+AWAPHSSCH+C+ A+D QALIWDI MPRAIEDPILAYTA GEIN +QW+S
Sbjct: 264 NHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWAS 323
Query: 543 LQPDWISICYTSALEILRV 599
QPDWI+ICY + LEILRV
Sbjct: 324 TQPDWIAICYNNCLEILRV 342
>sp|Q9XGN1|TTG1_ARATH TRANSPARENT TESTA GLABRA 1 protein (TTG1 protein)
Length = 341
Score = 206 bits (524), Expect = 5e-53
Identities = 106/202 (52%), Positives = 136/202 (67%), Gaps = 3/202 (1%)
Frame = +3
Query: 3 TCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRM 182
TCTIW +E V +TQLIAHDKEV+DIA+ +A +FASV AD SVR+
Sbjct: 156 TCTIWDIEKSVV-----------ETQLIAHDKEVHDIAWGEAR----VFASVSADGSVRI 200
Query: 183 FDLRHLEHSTIIYEDPNKSA-LLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARL 359
FDLR EHSTIIYE P LLRLAWNKQD Y+AT ++S ++++LD+R P PVA L
Sbjct: 201 FDLRDKEHSTIIYESPQPDTPLLRLAWNKQDLRYMATILMDSNKVVILDIRSPTMPVAEL 260
Query: 360 NNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNM--PRAIEDPILAYTAAGEINQIQ 533
H+ VN +AWAP S H+CSG +D QALIW++ + P I DP+ Y+A EINQ+Q
Sbjct: 261 ERHQASVNAIAWAPQSCKHICSGGDDTQALIWELPTVAGPNGI-DPMSVYSAGSEINQLQ 319
Query: 534 WSSLQPDWISICYTSALEILRV 599
WSS QPDWI I + + +++LRV
Sbjct: 320 WSSSQPDWIGIAFANKMQLLRV 341
>sp|O22469|MSI3_ARATH WD-40 repeat protein MSI3
Length = 424
Score = 50.8 bits (120), Expect = 3e-06
Identities = 47/183 (25%), Positives = 86/183 (46%), Gaps = 16/183 (8%)
Frame = +3
Query: 90 HDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLR--HLEHSTIIYEDPNKSALLRLAWN 263
H + D+A+ +IF S G D + ++DLR ++H ++E + L++N
Sbjct: 217 HQSIIEDVAWHMKN--ENIFGSAGDDCQLVIWDLRTNQMQHQVKVHE----REINYLSFN 270
Query: 264 KQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQ 443
+ LAT + +S + + D+R P+ L+ H G V V W P+ L S ED +
Sbjct: 271 PFNEWVLATASSDST-VALFDLRKLTAPLHVLSKHEGEVFQVEWDPNHETVLASSGEDRR 329
Query: 444 ALIWDIT-------NMPRAIED--PILAYTAAG---EINQIQWSSLQPDWI--SICYTSA 581
++WDI + ED P L ++ G +I+ W+ +P W+ S+ ++
Sbjct: 330 LMVWDINRVGDEQLEIELDAEDGPPELLFSHGGHKAKISDFAWNKDEP-WVISSVAEDNS 388
Query: 582 LEI 590
L++
Sbjct: 389 LQV 391
Score = 33.9 bits (76), Expect = 0.40
Identities = 14/42 (33%), Positives = 23/42 (54%)
Frame = +3
Query: 339 CTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDIT 464
C P RL H G+AW+ +L SG++D + +WD++
Sbjct: 159 CDPDLRLMGHEQEGYGLAWSSFKEGYLLSGSQDQRICLWDVS 200
Score = 33.1 bits (74), Expect = 0.69
Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 5/75 (6%)
Frame = +3
Query: 252 LAWNKQDANYLATFTLNSPEIIVLDMRVPCT-----PVARLNNHRGCVNGVAWAPHSSCH 416
LAW+ YL + + + I + D+ T P+ H+ + VAW +
Sbjct: 175 LAWSSFKEGYLLSGSQDQ-RICLWDVSATATDKVLNPMHVYEGHQSIIEDVAWHMKNENI 233
Query: 417 LCSGAEDCQALIWDI 461
S +DCQ +IWD+
Sbjct: 234 FGSAGDDCQLVIWDL 248
>sp|P90916|LIN53_CAEEL Trp-Asp repeats containing protein lin-53 (Abnormal cell lineage
protein 53)
Length = 385
Score = 50.4 bits (119), Expect = 4e-06
Identities = 51/205 (24%), Positives = 90/205 (43%), Gaps = 10/205 (4%)
Frame = +3
Query: 15 WSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLR 194
W + Q + Q K H+ V D+A+ G +F SVG D + ++D+R
Sbjct: 168 WDINANQNVAGELQAKDVFK----GHESVVEDVAWHVLHDG--VFGSVGDDKKLLIWDVR 221
Query: 195 HLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRG 374
I D + + + LA+N LAT + + + + D+R + +HR
Sbjct: 222 TSTPGHCI--DAHSAEVNCLAFNPYSEFILATGSADKT-VALWDLRNLRMKLHSFESHRD 278
Query: 375 CVNGVAWAPHSSCHLCSGAEDCQALIWDITNM--PRAIED-----PILAYTAAG---EIN 524
+ V W+PH+ L S D + +WD++ + ++ ED P L + G +I+
Sbjct: 279 EIFQVQWSPHNETILASSGTDKRLHVWDLSKIGEDQSAEDAEDGPPELLFIHGGHTAKIS 338
Query: 525 QIQWSSLQPDWISICYTSALEILRV 599
W+ +P W+ +C S IL+V
Sbjct: 339 DFSWNPNEP-WV-VCSVSEDNILQV 361
Score = 37.0 bits (84), Expect = 0.047
Identities = 37/166 (22%), Positives = 76/166 (45%), Gaps = 6/166 (3%)
Frame = +3
Query: 60 TGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEH------STIIY 221
T N +L H KE Y +++ G + S D +V +D+ ++ + ++
Sbjct: 129 TFNPLIRLKGHTKEGYGLSWNPNKEG--LILSASDDQTVCHWDINANQNVAGELQAKDVF 186
Query: 222 EDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAP 401
+ ++S + +AW+ + + ++++ D+R TP ++ H VN +A+ P
Sbjct: 187 KG-HESVVEDVAWHVLHDGVFGSVG-DDKKLLIWDVRTS-TPGHCIDAHSAEVNCLAFNP 243
Query: 402 HSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWS 539
+S L +G+ D +WD+ N+ + + EI Q+QWS
Sbjct: 244 YSEFILATGSADKTVALWDLRNLRMKLHS---FESHRDEIFQVQWS 286
>sp|O22607|MSI4_ARATH WD-40 repeat protein MSI4
Length = 507
Score = 49.7 bits (117), Expect = 7e-06
Identities = 46/189 (24%), Positives = 80/189 (42%), Gaps = 13/189 (6%)
Frame = +3
Query: 24 ETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLE 203
+TG+ + T + H+ V D+AF+ F SVG D+ + ++D R
Sbjct: 269 QTGEGTDKNESPTVGPRGVYHGHEDTVEDVAFSPTSAQE--FCSVGDDSCLILWDARTGT 326
Query: 204 HSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPC-----TPVARLNNH 368
+ E + + L + WN D N + T + ++ + + D R +P+ + H
Sbjct: 327 NPVTKVEKAHDADLHCVDWNPHDDNLILTGSADNT-VRLFDRRKLTANGVGSPIYKFEGH 385
Query: 369 RGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNM----PRAIEDPI-LAYTAAGEINQI- 530
+ V V W+P S S AED IWD + RA + P L + AG +++
Sbjct: 386 KAAVLCVQWSPDKSSVFGSSAEDGLLNIWDYDRVSKKSDRAAKSPAGLFFQHAGHRDKVV 445
Query: 531 --QWSSLQP 551
W++ P
Sbjct: 446 DFHWNASDP 454
>sp|Q8CFJ9|WDR24_MOUSE WD-repeat protein 24
Length = 790
Score = 48.9 bits (115), Expect = 1e-05
Identities = 37/133 (27%), Positives = 60/133 (45%), Gaps = 5/133 (3%)
Frame = +3
Query: 138 RDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLN-SPEI 314
R A+ G D V+++D+ + I+ +++ R+ W + ++LAT ++ I
Sbjct: 220 RGWLATGGRDKMVKVWDMT-THRAKEIHCVQTIASVARVKWRPECRHHLATCSMMVDHNI 278
Query: 315 IVLDMRVPCTPVARLNNHRGCVNGVAWA-PHSSCHLCSGAED---CQALIWDITNMPRAI 482
V D+R P P A HR G+AW PH L SG++D CQ L D +
Sbjct: 279 YVWDVRRPFVPAAMFEEHRDVTTGIAWRHPHDPSFLLSGSKDSTLCQHLFRDASQPVERA 338
Query: 483 EDPILAYTAAGEI 521
L Y G++
Sbjct: 339 NPEGLCYGLFGDL 351
>sp|Q96S15|WDR24_HUMAN WD-repeat protein 24
Length = 920
Score = 47.8 bits (112), Expect = 3e-05
Identities = 36/133 (27%), Positives = 60/133 (45%), Gaps = 5/133 (3%)
Frame = +3
Query: 138 RDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLN-SPEI 314
R A+ G D V+++D+ + ++ +++ R+ W + ++LAT ++ I
Sbjct: 350 RGWLATGGRDKMVKVWDMT-THRAKEMHCVQTIASVARVKWRPECRHHLATCSMMVDHNI 408
Query: 315 IVLDMRVPCTPVARLNNHRGCVNGVAWA-PHSSCHLCSGAED---CQALIWDITNMPRAI 482
V D+R P P A HR G+AW PH L SG++D CQ L D +
Sbjct: 409 YVWDVRRPFVPAAMFEEHRDVTTGIAWRHPHDPSFLLSGSKDSSLCQHLFRDASQPVERA 468
Query: 483 EDPILAYTAAGEI 521
L Y G++
Sbjct: 469 NPEGLCYGLFGDL 481
>sp|O22468|MSI2_ARATH WD-40 repeat protein MSI2
Length = 415
Score = 47.4 bits (111), Expect = 4e-05
Identities = 42/183 (22%), Positives = 87/183 (47%), Gaps = 16/183 (8%)
Frame = +3
Query: 90 HDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLR--HLEHSTIIYEDPNKSALLRLAWN 263
H+ + D+++ ++F S G D + ++D R ++H ++E + L++N
Sbjct: 216 HESAIADVSWHMKN--ENLFGSAGEDGRLVIWDTRTNQMQHQVKVHE----REVNYLSFN 269
Query: 264 KQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQ 443
+ LAT + +S + + D+R P+ +++H G V V W P+ L S ED +
Sbjct: 270 PFNEWVLATASSDST-VALFDLRKLNAPLHVMSSHEGEVFQVEWDPNHETVLASSGEDRR 328
Query: 444 ALIWDITNMPRA-------IED--PILAYTAAG---EINQIQWSSLQPDWI--SICYTSA 581
++WD+ + ED P L ++ G +I+ W+ +P W+ S+ ++
Sbjct: 329 LMVWDLNRVGEEQLEIELDAEDGPPELLFSHGGHKAKISDFAWNKNEP-WVIASVAEDNS 387
Query: 582 LEI 590
L++
Sbjct: 388 LQV 390
Score = 36.6 bits (83), Expect = 0.062
Identities = 15/46 (32%), Positives = 26/46 (56%)
Frame = +3
Query: 339 CTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPR 476
C P RL H G++W+P +L SG++D + +WD++ P+
Sbjct: 158 CDPDLRLVGHDKEGYGLSWSPFKEGYLLSGSQDQKICLWDVSATPQ 203
Score = 33.9 bits (76), Expect = 0.40
Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 16/150 (10%)
Frame = +3
Query: 60 TGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLE--------HSTI 215
T ++ Q+ H++EV ++F + A+ +D++V +FDLR L H
Sbjct: 249 TNQMQHQVKVHEREVNYLSFNPFNEW--VLATASSDSTVALFDLRKLNAPLHVMSSHEGE 306
Query: 216 IYE---DPNKSALLRLAWNKQDANYLATFTLN--SPEIIVLDMRVPCTPVARLNNHRGC- 377
+++ DPN +L + + L + LN E + +++ P L +H G
Sbjct: 307 VFQVEWDPNHETVLA---SSGEDRRLMVWDLNRVGEEQLEIELDAEDGPPELLFSHGGHK 363
Query: 378 --VNGVAWAPHSSCHLCSGAEDCQALIWDI 461
++ AW + + S AED +W +
Sbjct: 364 AKISDFAWNKNEPWVIASVAEDNSLQVWQM 393
>sp|Q04225|RRB1_YEAST Ribosome assembly protein RRB1
Length = 511
Score = 47.0 bits (110), Expect = 5e-05
Identities = 31/134 (23%), Positives = 65/134 (48%), Gaps = 7/134 (5%)
Frame = +3
Query: 84 IAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWN 263
++++K + DI +++ +FA+ G D +R++D R +H I + + + ++W+
Sbjct: 318 VSNNKSIEDIQWSRTES--TVFATAGCDGYIRIWDTRSKKHKPAISVKASNTDVNVISWS 375
Query: 264 KQDANYLATFTLNSPEIIVLDMRV-------PCTPVARLNNHRGCVNGVAWAPHSSCHLC 422
+ LA+ N V D+R PVA+ + H+G + +A+ P +
Sbjct: 376 DKIGYLLASGDDNGTWG-VWDLRQFTPSNADAVQPVAQYDFHKGAITSIAFNPLDESIVA 434
Query: 423 SGAEDCQALIWDIT 464
G+ED +WD++
Sbjct: 435 VGSEDNTVTLWDLS 448
>sp|O14021|PRW1_SCHPO RbAp48-related WD40-repeat protein prw1
Length = 431
Score = 46.6 bits (109), Expect = 6e-05
Identities = 34/136 (25%), Positives = 66/136 (48%), Gaps = 2/136 (1%)
Frame = +3
Query: 69 VKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYED--PNKSA 242
+K + +H+K+V D+ F +D+ ASV D + + D+R + ST +
Sbjct: 226 LKVHISSHEKQVSDVRFHYKH--QDLLASVSYDQYLHVHDIRRPDASTKPARSVHAHSGP 283
Query: 243 LLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLC 422
+ +A+N + LAT + + I + D+R + L H V ++++PH L
Sbjct: 284 IHSVAFNPHNDFILATCSTDKT-IALWDLRNLNQRLHTLEGHEDIVTKISFSPHEEPILA 342
Query: 423 SGAEDCQALIWDITNM 470
S + D + L+WD++ +
Sbjct: 343 STSADRRTLVWDLSRI 358
Score = 29.6 bits (65), Expect = 7.6
Identities = 28/114 (24%), Positives = 44/114 (38%), Gaps = 10/114 (8%)
Frame = +3
Query: 150 ASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDM 329
AS G ++S+R+ + + +Y P +L QD + +AT +++V D
Sbjct: 110 ASAGDESSLRV-------NISNLYSHPESVCSAKLM--PQDDSCVATVGNYHNDVLVFDK 160
Query: 330 RV----------PCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDI 461
P P RL H V W S L SG++D WD+
Sbjct: 161 ESFESYSSASESPLKPKYRLTKHTQPCTSVCWNFLSKGTLVSGSQDATLSCWDL 214
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,267,480
Number of Sequences: 369166
Number of extensions: 1498921
Number of successful extensions: 3779
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3486
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3744
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5733423530
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)