Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_A04
(692 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9CZE3|RAB32_MOUSE Ras-related protein Rab-32 231 1e-60
sp|Q13637|RAB32_HUMAN Ras-related protein Rab-32 231 1e-60
sp|Q8QZZ8|RAB38_MOUSE Ras-related protein Rab-38 222 8e-58
sp|P57729|RAB38_HUMAN Ras-related protein Rab-38 (Antigen N... 220 2e-57
sp|Q91YQ1|RAB7L_MOUSE Ras-related protein Rab-7L1 (Rab-7-li... 181 2e-45
sp|O14966|RAB7L_HUMAN Ras-related protein Rab-7L1 (Rab-7-li... 181 2e-45
sp|O94655|YPT7_SCHPO Ras-related protein ypt7 118 2e-26
sp|Q9C2L8|RAB7_NEUCR Probable Ras-related protein Rab7 111 2e-24
sp|Q15286|RAB35_HUMAN Ras-related protein Rab-35 (Rab-1C) (... 111 2e-24
sp|P61027|RAB10_MOUSE Ras-related protein Rab-10 >gi|465776... 110 5e-24
>sp|Q9CZE3|RAB32_MOUSE Ras-related protein Rab-32
Length = 223
Score = 231 bits (590), Expect = 1e-60
Identities = 118/192 (61%), Positives = 143/192 (74%), Gaps = 1/192 (0%)
Frame = +2
Query: 5 GKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQLWDIAGQERFGNMLRVYY 184
GKTSIIKRYVH+ FSQHYRATIGVDFALKVL WD ++VRLQLWDIAGQERFGNM RVYY
Sbjct: 35 GKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDIAGQERFGNMTRVYY 94
Query: 185 KDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCILLGNKSDCEREGRLSDT 364
K+A+GAF+V+D++R+STF+AV+KWK DLDSKV PNG PIP +LL NK D +++ S +
Sbjct: 95 KEALGAFVVFDISRSSTFDAVLKWKNDLDSKVHLPNGSPIPAVLLANKCDQKKDNSQSPS 154
Query: 365 NYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKMLKISLG-PEIKKDNDLIKLGNQK 541
+DQF +HGF F+TSAK+NI IDEA LV+ ML P + D D IKL +
Sbjct: 155 Q-MDQFCKDHGFTGWFETSAKDNINIDEATRFLVENMLANQQSFPSEEIDLDRIKLVEEP 213
Query: 542 PADKSSQDSKCC 577
P K S+CC
Sbjct: 214 PTTKPR--SQCC 223
>sp|Q13637|RAB32_HUMAN Ras-related protein Rab-32
Length = 225
Score = 231 bits (589), Expect = 1e-60
Identities = 115/191 (60%), Positives = 146/191 (76%)
Frame = +2
Query: 5 GKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQLWDIAGQERFGNMLRVYY 184
GKTSIIKRYVH+ FSQHYRATIGVDFALKVL WD ++VRLQLWDIAGQERFGNM RVYY
Sbjct: 37 GKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDIAGQERFGNMTRVYY 96
Query: 185 KDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCILLGNKSDCEREGRLSDT 364
K+A+GAF+V+D++R+STFEAV+KWK DLDSKV PNG PIP +LL NK D ++ S +
Sbjct: 97 KEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLLANKCDQNKDSSQSPS 156
Query: 365 NYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKMLKISLGPEIKKDNDLIKLGNQKP 544
+DQF EHGF F+TSAK+NI I+EAA LV+K+L ++ ++ND+ K+ +
Sbjct: 157 Q-VDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKIL-VNHQSFPNEENDVDKIKLDQE 214
Query: 545 ADKSSQDSKCC 577
++ S+CC
Sbjct: 215 TLRAENKSQCC 225
>sp|Q8QZZ8|RAB38_MOUSE Ras-related protein Rab-38
Length = 211
Score = 222 bits (565), Expect = 8e-58
Identities = 109/158 (68%), Positives = 127/158 (80%)
Frame = +2
Query: 5 GKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQLWDIAGQERFGNMLRVYY 184
GKTSIIKRYVH+ FS HYRATIGVDFALKVL WD +VVRLQLWDIAGQERFGNM RVYY
Sbjct: 21 GKTSIIKRYVHQNFSSHYRATIGVDFALKVLHWDPETVVRLQLWDIAGQERFGNMTRVYY 80
Query: 185 KDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCILLGNKSDCEREGRLSDT 364
++AMGAFIV+DVTR +TFEAV KWK DLDSK+T PNG P+ +LL NK D ++ +++
Sbjct: 81 REAMGAFIVFDVTRPATFEAVAKWKNDLDSKLTLPNGKPVSVVLLANKCDQGKDVLMNNG 140
Query: 365 NYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKML 478
+DQF EHGFV F+TSAKENI IDEA+ LV +L
Sbjct: 141 LKMDQFCKEHGFVGWFETSAKENINIDEASRCLVKHIL 178
>sp|P57729|RAB38_HUMAN Ras-related protein Rab-38 (Antigen NY-MEL-1)
Length = 211
Score = 220 bits (561), Expect = 2e-57
Identities = 108/158 (68%), Positives = 127/158 (80%)
Frame = +2
Query: 5 GKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQLWDIAGQERFGNMLRVYY 184
GKTSIIKRYVH+ FS HYRATIGVDFALKVL WD +VVRLQLWDIAGQERFGNM RVYY
Sbjct: 21 GKTSIIKRYVHQNFSSHYRATIGVDFALKVLHWDPETVVRLQLWDIAGQERFGNMTRVYY 80
Query: 185 KDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCILLGNKSDCEREGRLSDT 364
++AMGAFIV+DVTR +TFEAV KWK DLDSK++ PNG P+ +LL NK D ++ +++
Sbjct: 81 REAMGAFIVFDVTRPATFEAVAKWKNDLDSKLSLPNGKPVSVVLLANKCDQGKDVLMNNG 140
Query: 365 NYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKML 478
+DQF EHGFV F+TSAKENI IDEA+ LV +L
Sbjct: 141 LKMDQFCKEHGFVGWFETSAKENINIDEASRCLVKHIL 178
>sp|Q91YQ1|RAB7L_MOUSE Ras-related protein Rab-7L1 (Rab-7-like protein 1)
Length = 204
Score = 181 bits (459), Expect = 2e-45
Identities = 88/161 (54%), Positives = 116/161 (72%)
Frame = +2
Query: 5 GKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQLWDIAGQERFGNMLRVYY 184
GKTS+++RY FS+HY++T+GVDFALKVL W DS +VRLQLWDIAGQERF +M R+YY
Sbjct: 19 GKTSLVQRYSQDSFSKHYKSTVGVDFALKVLQWSDSEMVRLQLWDIAGQERFTSMTRLYY 78
Query: 185 KDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCILLGNKSDCEREGRLSDT 364
+DA I++DVT A+TF +WK+DLDSK+T P+G+P+PC+LL NKSD D
Sbjct: 79 RDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPSGEPVPCLLLANKSDLSPWAVSRD- 137
Query: 365 NYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKMLKIS 487
+D+F E+GF +TS KEN I+EA LV+KM+ S
Sbjct: 138 -QIDRFSKENGFTGWTETSVKENKNINEAMRVLVEKMMNNS 177
>sp|O14966|RAB7L_HUMAN Ras-related protein Rab-7L1 (Rab-7-like protein 1)
Length = 203
Score = 181 bits (458), Expect = 2e-45
Identities = 85/161 (52%), Positives = 116/161 (72%)
Frame = +2
Query: 5 GKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQLWDIAGQERFGNMLRVYY 184
GKTS+++RY FS+HY++T+GVDFALKVL W D +VRLQLWDIAGQERF +M R+YY
Sbjct: 19 GKTSLVQRYSQDSFSKHYKSTVGVDFALKVLQWSDYEIVRLQLWDIAGQERFTSMTRLYY 78
Query: 185 KDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCILLGNKSDCEREGRLSDT 364
+DA I++DVT A+TF +WK+DLDSK+T PNG+P+PC+LL NK C+
Sbjct: 79 RDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPNGEPVPCLLLANK--CDLSPWAVSR 136
Query: 365 NYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKMLKIS 487
+ +D+F E+GF +TS KEN I+EA L++KM++ S
Sbjct: 137 DQIDRFSKENGFTGWTETSVKENKNINEAMRVLIEKMMRNS 177
>sp|O94655|YPT7_SCHPO Ras-related protein ypt7
Length = 205
Score = 118 bits (295), Expect = 2e-26
Identities = 73/191 (38%), Positives = 103/191 (53%), Gaps = 1/191 (0%)
Frame = +2
Query: 5 GKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQLWDIAGQERFGNMLRVYY 184
GKTSI+ +YV++ FS+ Y+ATIG DF K + DD VV LQLWD AGQERF ++ +Y
Sbjct: 20 GKTSIMNQYVNRKFSKDYKATIGADFLTKEVLVDDK-VVTLQLWDTAGQERFQSLGVAFY 78
Query: 185 KDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCILLGNKSDCEREGRLSDT 364
+ A +VYDV + +FE + W+ + + + N + P ILLGNK D E + R+
Sbjct: 79 RGADCCVLVYDVNNSKSFETLDSWRDEFLIQASPSNPETFPFILLGNKVDVEEQKRMVSK 138
Query: 365 NYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKMLKISLGPEIKKD-NDLIKLGNQK 541
+ F G + F+TSAKE I + EA + L+ +I D D I L
Sbjct: 139 SKALAFCQARGEIPYFETSAKEAINVQEAFETVAKLALENMDSDDIAADFTDPIHL---- 194
Query: 542 PADKSSQDSKC 574
D SQ + C
Sbjct: 195 --DMESQKTSC 203
>sp|Q9C2L8|RAB7_NEUCR Probable Ras-related protein Rab7
Length = 205
Score = 111 bits (278), Expect = 2e-24
Identities = 61/169 (36%), Positives = 92/169 (54%)
Frame = +2
Query: 5 GKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQLWDIAGQERFGNMLRVYY 184
GKTS++ +YV+K FS Y+ATIG DF + + DD V +QLWD AGQERF ++ +Y
Sbjct: 20 GKTSLMNQYVNKKFSASYKATIGADFLTREVLVDDRQVT-MQLWDTAGQERFQSLGVAFY 78
Query: 185 KDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCILLGNKSDCEREGRLSDT 364
+ A +VYDV + +F+A+ W+ + + + + D P ++LGNK D E R+ T
Sbjct: 79 RGADCCVLVYDVNNSKSFDALDSWRDEFLIQASPRDPDNFPFVVLGNKIDMEESKRVIST 138
Query: 365 NYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKMLKISLGPEIKKD 511
F G + F+TSAKE I +++A + L E D
Sbjct: 139 KRAMTFCQSKGNIPYFETSAKEAINVEQAFEVIARNALMQEESEEFSGD 187
>sp|Q15286|RAB35_HUMAN Ras-related protein Rab-35 (Rab-1C) (GTP-binding protein RAY)
sp|Q5U316|RAB35_RAT Ras-related protein Rab-35
sp|Q6PHN9|RAB35_MOUSE Ras-related protein Rab-35
Length = 201
Score = 111 bits (277), Expect = 2e-24
Identities = 65/195 (33%), Positives = 109/195 (55%), Gaps = 4/195 (2%)
Frame = +2
Query: 5 GKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQLWDIAGQERFGNMLRVYY 184
GK+S++ R+ FS Y TIGVDF ++ + + V +LQ+WD AGQERF + YY
Sbjct: 20 GKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKV-KLQIWDTAGQERFRTITSTYY 78
Query: 185 KDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCILLGNKSDCEREGRLSDT 364
+ G +VYDVT A +F V +W +++ N D + IL+GNK+D + E ++ +T
Sbjct: 79 RGTHGVIVVYDVTSAESFVNVKRWLHEINQ-----NCDDVCRILVGNKND-DPERKVVET 132
Query: 365 NYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKMLKIS----LGPEIKKDNDLIKLG 532
+F + G ++ F+TSAKEN+ ++E N + + +L+ + ++ ND++KL
Sbjct: 133 EDAYKFAGQMG-IQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQQQQNDVVKL- 190
Query: 533 NQKPADKSSQDSKCC 577
S + +CC
Sbjct: 191 ----TKNSKRKKRCC 201
>sp|P61027|RAB10_MOUSE Ras-related protein Rab-10
sp|P61026|RAB10_HUMAN Ras-related protein Rab-10
Length = 200
Score = 110 bits (274), Expect = 5e-24
Identities = 66/191 (34%), Positives = 104/191 (54%)
Frame = +2
Query: 5 GKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQLWDIAGQERFGNMLRVYY 184
GKT ++ R+ F+ + +TIG+DF +K + + +LQ+WD AGQERF + YY
Sbjct: 21 GKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKI-KLQIWDTAGQERFHTITTSYY 79
Query: 185 KDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCILLGNKSDCEREGRLSDT 364
+ AMG +VYD+T +FE + KW +++D + + +LLGNK D + + R+
Sbjct: 80 RGAMGIMLVYDITNGKSFENISKWLRNIDEHA----NEDVERMLLGNKCDMD-DKRVVPK 134
Query: 365 NYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKMLKISLGPEIKKDNDLIKLGNQKP 544
+Q EHG ++ F+TSAK NI I++A L + +L+ + E +N I G
Sbjct: 135 GKGEQIAREHG-IRFFETSAKANINIEKAFLTLAEDILRKTPVKEPNSENVDISSGGGVT 193
Query: 545 ADKSSQDSKCC 577
K SKCC
Sbjct: 194 GWK----SKCC 200
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,345,055
Number of Sequences: 369166
Number of extensions: 1568002
Number of successful extensions: 4810
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4363
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4444
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5976365205
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)