Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_P04
(395 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9Y490|TLN1_HUMAN Talin-1 96 3e-20
sp|Q9Y4G6|TLN2_HUMAN Talin-2 96 3e-20
sp|Q71LX4|TLN2_MOUSE Talin-2 96 3e-20
sp|P26039|TLN1_MOUSE Talin-1 95 4e-20
sp|P54939|TLN1_CHICK Talin-1 95 6e-20
sp|P54633|TALA_DICDI Filopodin (Talin homolog) 57 1e-08
sp|Q70E73|RAPH1_HUMAN Ras-associated and pleckstrin homolog... 33 0.21
sp|Q92556|ELMO1_HUMAN Engulfment and cell motility protein ... 33 0.27
sp|Q8BPU7|ELMO1_MOUSE Engulfment and cell motility protein ... 33 0.27
sp|Q9N179|41_BOVIN Protein 4.1 (Band 4.1) (P4.1) (4.1R) 32 0.46
>sp|Q9Y490|TLN1_HUMAN Talin-1
Length = 2541
Score = 95.5 bits (236), Expect = 3e-20
Identities = 47/120 (39%), Positives = 76/120 (63%)
Frame = +1
Query: 13 VKLDLDTVVYDICRDLFKRIPQNQNLLVEEFGLFVPDPDSTRAYWLDNSKPVSYYPLGDK 192
++ + T+VYD CR + +RIP+ +FGLF+ D D + WL+ K + YY L +
Sbjct: 17 MQFEPSTMVYDACRIIRERIPEAPAGPPSDFGLFLSDDDPKKGIWLEAGKALDYYMLRNG 76
Query: 193 SLILLFKSRLRRLIIRTMDDTKKTLEVDDSKSIAEIIFPICNKMGISNHEEYSLIHELGE 372
+ ++ + R L IR +D T KT+ VDDSK++ +++ IC ++GI+NH+EYSL+ EL E
Sbjct: 77 DT-MEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICARIGITNHDEYSLVRELME 135
>sp|Q9Y4G6|TLN2_HUMAN Talin-2
Length = 2542
Score = 95.5 bits (236), Expect = 3e-20
Identities = 46/117 (39%), Positives = 75/117 (64%)
Frame = +1
Query: 13 VKLDLDTVVYDICRDLFKRIPQNQNLLVEEFGLFVPDPDSTRAYWLDNSKPVSYYPLGDK 192
++ + T VYD CR + +R+P+ Q ++GLF+ D D + WL+ + + YY L +
Sbjct: 19 MQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRKGIWLEAGRTLDYYMLRNG 78
Query: 193 SLILLFKSRLRRLIIRTMDDTKKTLEVDDSKSIAEIIFPICNKMGISNHEEYSLIHE 363
IL +K + R IR +D + KT+ VDDSK++ E++ IC+++GI+N+EEYSLI E
Sbjct: 79 D-ILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSLIQE 134
>sp|Q71LX4|TLN2_MOUSE Talin-2
Length = 2375
Score = 95.5 bits (236), Expect = 3e-20
Identities = 46/117 (39%), Positives = 75/117 (64%)
Frame = +1
Query: 13 VKLDLDTVVYDICRDLFKRIPQNQNLLVEEFGLFVPDPDSTRAYWLDNSKPVSYYPLGDK 192
++ + T VYD CR + +R+P+ Q ++GLF+ D D + WL+ + + YY L +
Sbjct: 19 MQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRKGIWLEAGRTLDYYMLRNG 78
Query: 193 SLILLFKSRLRRLIIRTMDDTKKTLEVDDSKSIAEIIFPICNKMGISNHEEYSLIHE 363
IL +K + R IR +D + KT+ VDDSK++ E++ IC+++GI+N+EEYSLI E
Sbjct: 79 D-ILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSLIQE 134
>sp|P26039|TLN1_MOUSE Talin-1
Length = 2541
Score = 95.1 bits (235), Expect = 4e-20
Identities = 47/120 (39%), Positives = 76/120 (63%)
Frame = +1
Query: 13 VKLDLDTVVYDICRDLFKRIPQNQNLLVEEFGLFVPDPDSTRAYWLDNSKPVSYYPLGDK 192
++ + T+VYD CR + +RIP+ +FGLF+ D D + WL+ K + YY L +
Sbjct: 17 MQFEPSTMVYDACRMIRERIPEALAGPPNDFGLFLSDDDPKKGIWLEAGKALDYYMLRNG 76
Query: 193 SLILLFKSRLRRLIIRTMDDTKKTLEVDDSKSIAEIIFPICNKMGISNHEEYSLIHELGE 372
+ ++ + R L IR +D T KT+ VDDSK++ +++ IC ++GI+NH+EYSL+ EL E
Sbjct: 77 DT-MEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICARIGITNHDEYSLVRELME 135
>sp|P54939|TLN1_CHICK Talin-1
Length = 2541
Score = 94.7 bits (234), Expect = 6e-20
Identities = 46/120 (38%), Positives = 77/120 (64%)
Frame = +1
Query: 13 VKLDLDTVVYDICRDLFKRIPQNQNLLVEEFGLFVPDPDSTRAYWLDNSKPVSYYPLGDK 192
++ + T+VYD CR + +R+P+ Q +FGLF+ D D + WL+ K + YY L +
Sbjct: 17 MQFEPSTMVYDACRMIRERVPEAQMGQPNDFGLFLSDEDPKKGIWLEAGKALDYYMLRNG 76
Query: 193 SLILLFKSRLRRLIIRTMDDTKKTLEVDDSKSIAEIIFPICNKMGISNHEEYSLIHELGE 372
+ +K + R L IR +D T KT+ VDDSK++ +++ IC ++GI+N++EYSL+ E+ E
Sbjct: 77 DT-MEYKKKQRPLKIRMLDGTVKTVMVDDSKTVTDMLTTICARIGITNYDEYSLVREIME 135
>sp|P54633|TALA_DICDI Filopodin (Talin homolog)
Length = 2492
Score = 57.0 bits (136), Expect = 1e-08
Identities = 35/115 (30%), Positives = 60/115 (52%), Gaps = 1/115 (0%)
Frame = +1
Query: 28 DTVVYDICRDLFKRIPQNQNLLVEEFGLFVPDPDSTR-AYWLDNSKPVSYYPLGDKSLIL 204
D + + C +F++ + + GL+ + + A WL K + +Y + L
Sbjct: 23 DMCIQECCTHIFEKTNEGG----PDHGLYQAHIEGKQSARWLAMEKTLQFYDINSDQQ-L 77
Query: 205 LFKSRLRRLIIRTMDDTKKTLEVDDSKSIAEIIFPICNKMGISNHEEYSLIHELG 369
+K + R + +D T KT VD+S++++EI+ IC KMGI N EEYSL++ G
Sbjct: 78 DYKKKHRPQKFKLLDGTIKTQLVDESQNVSEIVNSICKKMGIKNPEEYSLMNSAG 132
>sp|Q70E73|RAPH1_HUMAN Ras-associated and pleckstrin homology domains-containing protein 1
(RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2)
(preL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2
chromosomal region candidate gene 9 protein)
Length = 1302
Score = 33.1 bits (74), Expect = 0.21
Identities = 14/61 (22%), Positives = 38/61 (62%), Gaps = 2/61 (3%)
Frame = +1
Query: 211 KSRLRRLIIRT--MDDTKKTLEVDDSKSIAEIIFPICNKMGISNHEEYSLIHELGEIERT 384
++++++L+IR DD+ KT+ VD+ +++ +++ + +K ++SL+ + E++
Sbjct: 317 EAQVKKLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETVSELQME 376
Query: 385 R 387
R
Sbjct: 377 R 377
>sp|Q92556|ELMO1_HUMAN Engulfment and cell motility protein 1 (CED-12 homolog)
Length = 727
Score = 32.7 bits (73), Expect = 0.27
Identities = 12/34 (35%), Positives = 22/34 (64%)
Frame = +1
Query: 259 KTLEVDDSKSIAEIIFPICNKMGISNHEEYSLIH 360
K +E+D K ++ II +C+ ++NHE ++L H
Sbjct: 20 KLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQH 53
>sp|Q8BPU7|ELMO1_MOUSE Engulfment and cell motility protein 1 (CED-12 homolog)
Length = 727
Score = 32.7 bits (73), Expect = 0.27
Identities = 12/34 (35%), Positives = 22/34 (64%)
Frame = +1
Query: 259 KTLEVDDSKSIAEIIFPICNKMGISNHEEYSLIH 360
K +E+D K ++ II +C+ ++NHE ++L H
Sbjct: 20 KLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQH 53
>sp|Q9N179|41_BOVIN Protein 4.1 (Band 4.1) (P4.1) (4.1R)
Length = 617
Score = 32.0 bits (71), Expect = 0.46
Identities = 21/56 (37%), Positives = 33/56 (58%), Gaps = 8/56 (14%)
Frame = +1
Query: 25 LDTVVYDIC-------RDLFKRIPQNQNLLVEE-FGLFVPDPDSTRAYWLDNSKPV 168
LD VY+ +DL KR+ ++ NLL E+ FGL + D ++T WLD++K +
Sbjct: 8 LDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWD-NATSKTWLDSAKEI 62
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,293,037
Number of Sequences: 369166
Number of extensions: 705683
Number of successful extensions: 1988
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1960
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1983
length of database: 68,354,980
effective HSP length: 97
effective length of database: 50,435,685
effective search space used: 1714813290
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)