Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_P03
(244 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q16943|VP33_APLCA Vesicle-associated membrane protein/sy... 112 2e-25
sp|O95292|VAPB_HUMAN Vesicle-associated membrane protein-as... 109 2e-24
sp|Q9Z269|VAPB_RAT Vesicle-associated membrane protein-asso... 109 2e-24
sp|Q9QY76|VAPB_MOUSE Vesicle-associated membrane protein-as... 108 5e-24
sp|Q9P0L0|VAPA_HUMAN Vesicle-associated membrane protein-as... 107 1e-23
sp|Q9WV55|VAPA_MOUSE Vesicle-associated membrane protein-as... 106 2e-23
sp|Q9Z270|VAPA_RAT Vesicle-associated membrane protein-asso... 106 2e-23
sp|Q10484|YDFC_SCHPO Hypothetical protein C17C9.12 in chrom... 64 1e-10
sp|P40075|SCS2_YEAST SCS2 protein 54 1e-07
sp|Q8NHP6|MSPD2_HUMAN Motile sperm domain containing protein 2 50 2e-06
>sp|Q16943|VP33_APLCA Vesicle-associated membrane protein/synaptobrevin binding protein
(VAP-33)
Length = 260
Score = 112 bits (281), Expect = 2e-25
Identities = 51/75 (68%), Positives = 61/75 (81%)
Frame = +3
Query: 18 EQILLISPNNELKFYGPFTQVVTSHLKLTNPTNSNVCFKVKTTAPKQYCVRPNSGNIEPK 197
EQ L++ P EL+F GPFT VVT+ LKL+NPT+ +CFKVKTTAPK+YCVRPNSG +EPK
Sbjct: 5 EQALILEPAGELRFKGPFTDVVTADLKLSNPTDRRICFKVKTTAPKRYCVRPNSGILEPK 64
Query: 198 KSFDIAVMLQPFKYD 242
S +AVMLQPF YD
Sbjct: 65 TSIAVAVMLQPFNYD 79
>sp|O95292|VAPB_HUMAN Vesicle-associated membrane protein-associated protein B/C
(VAMP-associated protein B/C) (VAMP-B/VAMP-C)
(VAP-B/VAP-C)
Length = 243
Score = 109 bits (273), Expect = 2e-24
Identities = 50/75 (66%), Positives = 62/75 (82%)
Frame = +3
Query: 18 EQILLISPNNELKFYGPFTQVVTSHLKLTNPTNSNVCFKVKTTAPKQYCVRPNSGNIEPK 197
EQ+L + P +ELKF GPFT VVT++LKL NPT+ NVCFKVKTTAP++YCVRPNSG I+
Sbjct: 5 EQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGIIDAG 64
Query: 198 KSFDIAVMLQPFKYD 242
S +++VMLQPF YD
Sbjct: 65 ASINVSVMLQPFDYD 79
>sp|Q9Z269|VAPB_RAT Vesicle-associated membrane protein-associated protein B
(VAMP-associated protein B) (VAMP-B) (VAP-B)
Length = 243
Score = 109 bits (273), Expect = 2e-24
Identities = 50/75 (66%), Positives = 62/75 (82%)
Frame = +3
Query: 18 EQILLISPNNELKFYGPFTQVVTSHLKLTNPTNSNVCFKVKTTAPKQYCVRPNSGNIEPK 197
EQ+L + P +ELKF GPFT VVT++LKL NPT+ NVCFKVKTTAP++YCVRPNSG I+
Sbjct: 5 EQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGVIDAG 64
Query: 198 KSFDIAVMLQPFKYD 242
S +++VMLQPF YD
Sbjct: 65 ASLNVSVMLQPFDYD 79
>sp|Q9QY76|VAPB_MOUSE Vesicle-associated membrane protein-associated protein B
(VAMP-associated protein B) (VAMP-associated protein
33b) (VAMP-B) (VAP-B)
Length = 243
Score = 108 bits (269), Expect = 5e-24
Identities = 49/75 (65%), Positives = 61/75 (81%)
Frame = +3
Query: 18 EQILLISPNNELKFYGPFTQVVTSHLKLTNPTNSNVCFKVKTTAPKQYCVRPNSGNIEPK 197
EQ+L + P +ELKF GPFT VVT++LKL NPT+ NVCFKVKTT P++YCVRPNSG I+
Sbjct: 5 EQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTVPRRYCVRPNSGVIDAG 64
Query: 198 KSFDIAVMLQPFKYD 242
S +++VMLQPF YD
Sbjct: 65 ASLNVSVMLQPFDYD 79
>sp|Q9P0L0|VAPA_HUMAN Vesicle-associated membrane protein-associated protein A
(VAMP-associated protein A) (VAMP-A) (VAP-A) (33 kDa
Vamp-associated protein) (VAP-33)
Length = 242
Score = 107 bits (266), Expect = 1e-23
Identities = 48/77 (62%), Positives = 62/77 (80%)
Frame = +3
Query: 12 RKEQILLISPNNELKFYGPFTQVVTSHLKLTNPTNSNVCFKVKTTAPKQYCVRPNSGNIE 191
+ EQIL++ P +LKF GPFT VVT++LKL NP++ VCFKVKTTAP++YCVRPNSG I+
Sbjct: 3 KHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGIID 62
Query: 192 PKKSFDIAVMLQPFKYD 242
P + ++VMLQPF YD
Sbjct: 63 PGSTVTVSVMLQPFDYD 79
>sp|Q9WV55|VAPA_MOUSE Vesicle-associated membrane protein-associated protein A
(VAMP-associated protein A) (VAMP-A) (VAP-A) (33 kDa
Vamp-associated protein) (VAP-33)
Length = 242
Score = 106 bits (264), Expect = 2e-23
Identities = 48/77 (62%), Positives = 62/77 (80%)
Frame = +3
Query: 12 RKEQILLISPNNELKFYGPFTQVVTSHLKLTNPTNSNVCFKVKTTAPKQYCVRPNSGNIE 191
+ EQIL++ P ++LKF GPFT VVT++LKL NP++ VCFKVKTTAP++YCVRPNSG I+
Sbjct: 3 KHEQILVLDPPSDLKFKGPFTDVVTTNLKLQNPSDRKVCFKVKTTAPRRYCVRPNSGIID 62
Query: 192 PKKSFDIAVMLQPFKYD 242
P ++VMLQPF YD
Sbjct: 63 PGSIVTVSVMLQPFDYD 79
>sp|Q9Z270|VAPA_RAT Vesicle-associated membrane protein-associated protein A
(VAMP-associated protein A) (VAMP-A) (VAP-A) (33 kDa
Vamp-associated protein) (VAP-33)
Length = 242
Score = 106 bits (264), Expect = 2e-23
Identities = 48/77 (62%), Positives = 62/77 (80%)
Frame = +3
Query: 12 RKEQILLISPNNELKFYGPFTQVVTSHLKLTNPTNSNVCFKVKTTAPKQYCVRPNSGNIE 191
+ EQIL++ P ++LKF GPFT VVT++LKL NP++ VCFKVKTTAP++YCVRPNSG I+
Sbjct: 3 KHEQILVLDPPSDLKFKGPFTDVVTTNLKLQNPSDRKVCFKVKTTAPRRYCVRPNSGVID 62
Query: 192 PKKSFDIAVMLQPFKYD 242
P ++VMLQPF YD
Sbjct: 63 PGSIVTVSVMLQPFDYD 79
>sp|Q10484|YDFC_SCHPO Hypothetical protein C17C9.12 in chromosome I
Length = 319
Score = 63.5 bits (153), Expect = 1e-10
Identities = 30/67 (44%), Positives = 42/67 (62%)
Frame = +3
Query: 42 NNELKFYGPFTQVVTSHLKLTNPTNSNVCFKVKTTAPKQYCVRPNSGNIEPKKSFDIAVM 221
++ + F P T++V L+L N + FKVKTTAPKQYCVRPN G IE + + V+
Sbjct: 6 DSTIVFPRPLTRLVKCDLELRNTAPYPIGFKVKTTAPKQYCVRPNGGRIEANSAVSVEVI 65
Query: 222 LQPFKYD 242
LQP ++
Sbjct: 66 LQPLDHE 72
>sp|P40075|SCS2_YEAST SCS2 protein
Length = 244
Score = 53.9 bits (128), Expect = 1e-07
Identities = 25/63 (39%), Positives = 40/63 (63%)
Frame = +3
Query: 33 ISPNNELKFYGPFTQVVTSHLKLTNPTNSNVCFKVKTTAPKQYCVRPNSGNIEPKKSFDI 212
ISP+ L + P T+ T + ++N ++ + FKVKTTAPK YCVRPN+ + P ++ +
Sbjct: 6 ISPD-VLVYKSPLTEQSTEYASISNNSDQTIAFKVKTTAPKFYCVRPNAAVVAPGETIQV 64
Query: 213 AVM 221
V+
Sbjct: 65 QVI 67
>sp|Q8NHP6|MSPD2_HUMAN Motile sperm domain containing protein 2
Length = 518
Score = 50.1 bits (118), Expect = 2e-06
Identities = 28/68 (41%), Positives = 41/68 (60%)
Frame = +3
Query: 15 KEQILLISPNNELKFYGPFTQVVTSHLKLTNPTNSNVCFKVKTTAPKQYCVRPNSGNIEP 194
K +L ISP EL F + + + LTN T + V FKV+TTAP++Y V+P++ + +P
Sbjct: 324 KGPLLHISPAEELYFGSTESGEKKTLIVLTNVTKNIVAFKVRTTAPEKYRVKPSNSSCDP 383
Query: 195 KKSFDIAV 218
S DI V
Sbjct: 384 GASVDIVV 391
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,026,896
Number of Sequences: 369166
Number of extensions: 395251
Number of successful extensions: 1124
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1121
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1124
length of database: 68,354,980
effective HSP length: 51
effective length of database: 58,933,495
effective search space used: 1709071355
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)