Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_O10
(705 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9Z2V4|PPCKC_MOUSE Phosphoenolpyruvate carboxykinase, cy... 288 1e-77
sp|P05153|PPCKC_CHICK Phosphoenolpyruvate carboxykinase, cy... 287 2e-77
sp|P07379|PPCKC_RAT Phosphoenolpyruvate carboxykinase, cyto... 286 4e-77
sp|P35558|PPCKC_HUMAN Phosphoenolpyruvate carboxykinase, cy... 285 8e-77
sp|Q5R5J1|PPCKC_PONPY Phosphoenolpyruvate carboxykinase, cy... 285 8e-77
sp|Q16822|PPCKM_HUMAN Phosphoenolpyruvate carboxykinase, mi... 278 1e-74
sp|P20007|PPCK_DROME Phosphoenolpyruvate carboxykinase [GTP... 277 2e-74
sp|Q8HYZ4|PPCKC_BOVIN Phosphoenolpyruvate carboxykinase, cy... 277 2e-74
sp|Q8BH04|PPCKM_MOUSE Phosphoenolpyruvate carboxykinase, mi... 276 3e-74
sp|P29190|PPCK_HAECO Phosphoenolpyruvate carboxykinase [GTP... 264 2e-70
>sp|Q9Z2V4|PPCKC_MOUSE Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 288 bits (737), Expect = 1e-77
Identities = 135/213 (63%), Positives = 159/213 (74%)
Frame = +2
Query: 2 PASQCPIIDKNWESPNGVPISAVIFGGRRPEGVPLVYETLNWQHGVFTGACVRSEATAAA 181
PASQCPIID WESP GVPI +IFGGRRPEGVPLVYE L+WQHGVF GA +RSEATAAA
Sbjct: 409 PASQCPIIDPAWESPEGVPIEGIIFGGRRPEGVPLVYEALSWQHGVFVGAAMRSEATAAA 468
Query: 182 EHKGKVVMNDPFAMRPFFGYNFGDYLKHWLSFAHESHYKLPRIYHVNWFRKSKEDGSFLW 361
EHKGK++M+DPFAMRPFFGYNFG YL HWLS AH KLP+I+HVNWFRK K DG FLW
Sbjct: 469 EHKGKIIMHDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPKIFHVNWFRKDK-DGKFLW 527
Query: 362 PGFGENSRVLDWIAKRVAGKAMGLKTAVGIIPRFEELNLSGLKITEKQYKELFSLPSEFW 541
PGFGENSRVL+W+ R+ G+ T +G IP+ LNL GL +ELF + EFW
Sbjct: 528 PGFGENSRVLEWMFGRIEGEDSAKLTPIGYIPKENALNLKGL--GGVNVEELFGISKEFW 585
Query: 542 NHEFEELEAYFKEQIGKDLPEEIKVELQNFRHR 640
E EE++ Y ++Q+ DLP EI+ EL+ + R
Sbjct: 586 EKEVEEIDRYLEDQVNTDLPYEIERELRALKQR 618
>sp|P05153|PPCKC_CHICK Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 287 bits (734), Expect = 2e-77
Identities = 134/207 (64%), Positives = 156/207 (75%)
Frame = +2
Query: 2 PASQCPIIDKNWESPNGVPISAVIFGGRRPEGVPLVYETLNWQHGVFTGACVRSEATAAA 181
PASQCPI+D WESP GVPI +IFGGRRP GVPLVYE NWQHGVF GA +RSEATAAA
Sbjct: 409 PASQCPIMDPAWESPEGVPIEGIIFGGRRPAGVPLVYEAFNWQHGVFIGAAMRSEATAAA 468
Query: 182 EHKGKVVMNDPFAMRPFFGYNFGDYLKHWLSFAHESHYKLPRIYHVNWFRKSKEDGSFLW 361
EHKGK++M+DPFAMRPFFGYNFG YL HWLS AH KLPRI+HVNWFRK + G FLW
Sbjct: 469 EHKGKIIMHDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPRIFHVNWFRKDSQ-GKFLW 527
Query: 362 PGFGENSRVLDWIAKRVAGKAMGLKTAVGIIPRFEELNLSGLKITEKQYKELFSLPSEFW 541
PG+GENSRVL+W+ R+ GKA TA+G IP LNL GL+ + ELF++ EFW
Sbjct: 528 PGYGENSRVLEWMFNRIQGKASAKSTAIGYIPADTALNLKGLE--DINLTELFNISKEFW 585
Query: 542 NHEFEELEAYFKEQIGKDLPEEIKVEL 622
E EE++ YF+ Q+ DLP EI+ EL
Sbjct: 586 EKEVEEIKQYFEGQVNADLPYEIEREL 612
>sp|P07379|PPCKC_RAT Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 286 bits (732), Expect = 4e-77
Identities = 133/213 (62%), Positives = 160/213 (75%)
Frame = +2
Query: 2 PASQCPIIDKNWESPNGVPISAVIFGGRRPEGVPLVYETLNWQHGVFTGACVRSEATAAA 181
PASQCPIID WESP GVPI +IFGGRRP GVPLVYE L+WQHGVF GA +RSEATAAA
Sbjct: 409 PASQCPIIDPAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAA 468
Query: 182 EHKGKVVMNDPFAMRPFFGYNFGDYLKHWLSFAHESHYKLPRIYHVNWFRKSKEDGSFLW 361
EHKGKV+M+DPFAMRPFFGYNFG YL HWLS AH KLP+I+HVNWFRK K +G FLW
Sbjct: 469 EHKGKVIMHDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPKIFHVNWFRKDK-NGKFLW 527
Query: 362 PGFGENSRVLDWIAKRVAGKAMGLKTAVGIIPRFEELNLSGLKITEKQYKELFSLPSEFW 541
PGFGENSRVL+W+ R+ G+ T +G +P+ + LNL GL + +ELF + EFW
Sbjct: 528 PGFGENSRVLEWMFGRIEGEDSAKLTPIGYVPKEDALNLKGL--GDVNVEELFGISKEFW 585
Query: 542 NHEFEELEAYFKEQIGKDLPEEIKVELQNFRHR 640
E EE++ Y ++Q+ DLP EI+ EL+ + R
Sbjct: 586 EKEVEEIDKYLEDQVNADLPYEIERELRALKQR 618
>sp|P35558|PPCKC_HUMAN Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 285 bits (729), Expect = 8e-77
Identities = 135/213 (63%), Positives = 158/213 (74%)
Frame = +2
Query: 2 PASQCPIIDKNWESPNGVPISAVIFGGRRPEGVPLVYETLNWQHGVFTGACVRSEATAAA 181
PASQCPIID WESP GVPI +IFGGRRP GVPLVYE L+WQHGVF GA +RSEATAAA
Sbjct: 409 PASQCPIIDAAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAA 468
Query: 182 EHKGKVVMNDPFAMRPFFGYNFGDYLKHWLSFAHESHYKLPRIYHVNWFRKSKEDGSFLW 361
EHKGK++M+DPFAMRPFFGYNFG YL HWLS A KLP+I+HVNWFRK KE G FLW
Sbjct: 469 EHKGKIIMHDPFAMRPFFGYNFGKYLAHWLSMAQHPAAKLPKIFHVNWFRKDKE-GKFLW 527
Query: 362 PGFGENSRVLDWIAKRVAGKAMGLKTAVGIIPRFEELNLSGLKITEKQYKELFSLPSEFW 541
PGFGENSRVL+W+ R+ GKA T +G IP+ + LNL GL ELFS+ EFW
Sbjct: 528 PGFGENSRVLEWMFNRIDGKASTKLTPIGYIPKEDALNLKGL--GHINMMELFSISKEFW 585
Query: 542 NHEFEELEAYFKEQIGKDLPEEIKVELQNFRHR 640
E E++E Y ++Q+ DLP EI+ E+ + R
Sbjct: 586 EKEVEDIEKYLEDQVNADLPCEIEREILALKQR 618
>sp|Q5R5J1|PPCKC_PONPY Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 285 bits (729), Expect = 8e-77
Identities = 135/213 (63%), Positives = 158/213 (74%)
Frame = +2
Query: 2 PASQCPIIDKNWESPNGVPISAVIFGGRRPEGVPLVYETLNWQHGVFTGACVRSEATAAA 181
PASQCPIID WESP GVPI +IFGGRRP GVPLVYE L+WQHGVF GA +RSEATAAA
Sbjct: 409 PASQCPIIDAAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAA 468
Query: 182 EHKGKVVMNDPFAMRPFFGYNFGDYLKHWLSFAHESHYKLPRIYHVNWFRKSKEDGSFLW 361
EHKGK++M+DPFAMRPFFGYNFG YL HWLS A KLP+I+HVNWFRK KE G FLW
Sbjct: 469 EHKGKIIMHDPFAMRPFFGYNFGKYLAHWLSMAQHPAAKLPKIFHVNWFRKDKE-GKFLW 527
Query: 362 PGFGENSRVLDWIAKRVAGKAMGLKTAVGIIPRFEELNLSGLKITEKQYKELFSLPSEFW 541
PGFGENSRVL+W+ R+ GKA T +G IP+ + LNL GL ELFS+ EFW
Sbjct: 528 PGFGENSRVLEWMFNRIDGKAGAKLTPIGYIPKEDALNLKGL--GHINVMELFSISKEFW 585
Query: 542 NHEFEELEAYFKEQIGKDLPEEIKVELQNFRHR 640
E E++E Y ++Q+ DLP EI+ E+ + R
Sbjct: 586 EKEVEDIEKYLEDQVNADLPCEIEREILALKQR 618
>sp|Q16822|PPCKM_HUMAN Phosphoenolpyruvate carboxykinase, mitochondrial precursor [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-M)
Length = 640
Score = 278 bits (711), Expect = 1e-74
Identities = 124/213 (58%), Positives = 160/213 (75%)
Frame = +2
Query: 2 PASQCPIIDKNWESPNGVPISAVIFGGRRPEGVPLVYETLNWQHGVFTGACVRSEATAAA 181
PA QCPI+D WE+P GVPI A+IFGGRRP+GVPLVYE NW+HGVF G +RSE+TAAA
Sbjct: 427 PARQCPIMDPAWEAPEGVPIDAIIFGGRRPKGVPLVYEAFNWRHGVFVGRAMRSESTAAA 486
Query: 182 EHKGKVVMNDPFAMRPFFGYNFGDYLKHWLSFAHESHYKLPRIYHVNWFRKSKEDGSFLW 361
EHKGK++M+DPFAMRPFFGYNFG YL+HWLS +LPRI+HVNWFR+ E G FLW
Sbjct: 487 EHKGKIIMHDPFAMRPFFGYNFGHYLEHWLSMEGRKGAQLPRIFHVNWFRRD-EAGHFLW 545
Query: 362 PGFGENSRVLDWIAKRVAGKAMGLKTAVGIIPRFEELNLSGLKITEKQYKELFSLPSEFW 541
PGFGEN+RVLDWI +R+ G+ +T +G++P+ L+LSGL+ + +LFSLP +FW
Sbjct: 546 PGFGENARVLDWICRRLEGEDSARETPIGLVPKEGALDLSGLRAIDT--TQLFSLPKDFW 603
Query: 542 NHEFEELEAYFKEQIGKDLPEEIKVELQNFRHR 640
E ++ +Y EQ+ +DLP+E+ EL+ R
Sbjct: 604 EQEVRDIRSYLTEQVNQDLPKEVLAELEALERR 636
>sp|P20007|PPCK_DROME Phosphoenolpyruvate carboxykinase [GTP] (Phosphoenolpyruvate
carboxylase) (PEPCK)
Length = 647
Score = 277 bits (708), Expect = 2e-74
Identities = 129/213 (60%), Positives = 162/213 (76%)
Frame = +2
Query: 2 PASQCPIIDKNWESPNGVPISAVIFGGRRPEGVPLVYETLNWQHGVFTGACVRSEATAAA 181
PA+QCPIID+ WE P GVPISA++FGGRRP GVPL+YE +W HGVF GA +RSEATAAA
Sbjct: 435 PAAQCPIIDEAWEDPAGVPISAMLFGGRRPAGVPLIYEARDWTHGVFIGAAMRSEATAAA 494
Query: 182 EHKGKVVMNDPFAMRPFFGYNFGDYLKHWLSFAHESHYKLPRIYHVNWFRKSKEDGSFLW 361
EHKGKV+M+DPFAMRPFFGYNFGDY+ HWLS E ++P+I+HVNWFRKS E G F+W
Sbjct: 495 EHKGKVIMHDPFAMRPFFGYNFGDYVAHWLSM--EKRGQVPKIFHVNWFRKSAE-GKFMW 551
Query: 362 PGFGENSRVLDWIAKRVAGKAMGLKTAVGIIPRFEELNLSGLKITEKQYKELFSLPSEFW 541
PG+GENSRVL+WI +RV G++ + +A+G IP LNL G+K + KE+FSLP EFW
Sbjct: 552 PGYGENSRVLEWILRRVNGESCYVDSAIGHIPAEGALNLDGMK-DKVDVKEIFSLPKEFW 610
Query: 542 NHEFEELEAYFKEQIGKDLPEEIKVELQNFRHR 640
+ E +++ YF+ Q+G DLP I +L R
Sbjct: 611 SQEVKDIRTYFESQVGADLPASIYQQLDELSSR 643
>sp|Q8HYZ4|PPCKC_BOVIN Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 277 bits (708), Expect = 2e-74
Identities = 132/213 (61%), Positives = 156/213 (73%)
Frame = +2
Query: 2 PASQCPIIDKNWESPNGVPISAVIFGGRRPEGVPLVYETLNWQHGVFTGACVRSEATAAA 181
PASQCPIID +WESP GVPI +IFGGRRP GVPLVYE L+WQHGVF GA +RSEATAAA
Sbjct: 409 PASQCPIIDPDWESPEGVPIEGIIFGGRRPVGVPLVYEALSWQHGVFVGAAMRSEATAAA 468
Query: 182 EHKGKVVMNDPFAMRPFFGYNFGDYLKHWLSFAHESHYKLPRIYHVNWFRKSKEDGSFLW 361
E+KGKV+M+DPFAM PFFGYNFG YL HWLS A KLP+I+HVNWFRK K G FLW
Sbjct: 469 EYKGKVIMHDPFAMGPFFGYNFGQYLAHWLSMAQRPAAKLPKIFHVNWFRKDKA-GRFLW 527
Query: 362 PGFGENSRVLDWIAKRVAGKAMGLKTAVGIIPRFEELNLSGLKITEKQYKELFSLPSEFW 541
PGFGENSRVL+W+ RV G+ T +G IP + L+L GL + KELF + EFW
Sbjct: 528 PGFGENSRVLEWMFNRVVGEGGASVTPIGYIPDEDALDLRGL--GDVDVKELFHISKEFW 585
Query: 542 NHEFEELEAYFKEQIGKDLPEEIKVELQNFRHR 640
E EE++ Y +EQ+ DLP EIK ++ + R
Sbjct: 586 EEEVEEIQKYLEEQVNVDLPPEIKNQVLALKQR 618
>sp|Q8BH04|PPCKM_MOUSE Phosphoenolpyruvate carboxykinase, mitochondrial precursor [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-M)
Length = 640
Score = 276 bits (707), Expect = 3e-74
Identities = 123/213 (57%), Positives = 159/213 (74%)
Frame = +2
Query: 2 PASQCPIIDKNWESPNGVPISAVIFGGRRPEGVPLVYETLNWQHGVFTGACVRSEATAAA 181
PA QCPI+D WE+P GVPI A+IFGGRRP+GVPLVYE NW+HGVF G+ +RSE+TAAA
Sbjct: 427 PARQCPIMDPAWEAPEGVPIDAIIFGGRRPKGVPLVYEAFNWRHGVFVGSAMRSESTAAA 486
Query: 182 EHKGKVVMNDPFAMRPFFGYNFGDYLKHWLSFAHESHYKLPRIYHVNWFRKSKEDGSFLW 361
EHKGK +M+DPFAMRPFFGYNFG YL+HWLS + +LPRI+HVNWFR+ E G FLW
Sbjct: 487 EHKGKTIMHDPFAMRPFFGYNFGRYLEHWLSMEGQKGARLPRIFHVNWFRRD-EAGRFLW 545
Query: 362 PGFGENSRVLDWIAKRVAGKAMGLKTAVGIIPRFEELNLSGLKITEKQYKELFSLPSEFW 541
PGFGEN+RVLDWI +R+ G+ +T +G++P+ L+LSGL + +LFS+P +FW
Sbjct: 546 PGFGENARVLDWICRRLEGEDSAQETPIGLVPKEGALDLSGLSAVDT--SQLFSIPKDFW 603
Query: 542 NHEFEELEAYFKEQIGKDLPEEIKVELQNFRHR 640
E ++ Y EQ+ +DLP+E+ EL+ R
Sbjct: 604 EQEVRDIRGYLTEQVNQDLPKEVLAELEALEGR 636
>sp|P29190|PPCK_HAECO Phosphoenolpyruvate carboxykinase [GTP] (Phosphoenolpyruvate
carboxylase) (PEPCK)
Length = 619
Score = 264 bits (675), Expect = 2e-70
Identities = 119/208 (57%), Positives = 159/208 (76%), Gaps = 1/208 (0%)
Frame = +2
Query: 2 PASQCPIIDKNWESPNGVPISAVIFGGRRPEGVPLVYETLNWQHGVFTGACVRSEATAAA 181
PASQCPII WESP GVPI A+IFGGRRP GVPLV+ET +W HG+FTGAC++SEATAAA
Sbjct: 405 PASQCPIIHPEWESPKGVPIDAIIFGGRRPAGVPLVFETRSWLHGIFTGACLKSEATAAA 464
Query: 182 EHKGKVVMNDPFAMRPFFGYNFGDYLKHWLSFAHESHYKLPRIYHVNWFRKSKEDGSFLW 361
EHKGK VM+DP AMRPF GYNFG YL+HW+ + K+P+IYHVNWFR+ + FLW
Sbjct: 465 EHKGKTVMHDPMAMRPFMGYNFGHYLQHWIDLNKDGR-KVPKIYHVNWFRRD-ANNKFLW 522
Query: 362 PGFGENSRVLDWIAKRVAGKA-MGLKTAVGIIPRFEELNLSGLKITEKQYKELFSLPSEF 538
PG+G+N RV+DWI +R+ G+ +G+ T +GI+P+ +N SGL + Q+ EL S+P E+
Sbjct: 523 PGYGQNIRVIDWIVRRLDGEPDIGVDTPIGIVPKKGAINASGL--PDIQWDELMSVPKEY 580
Query: 539 WNHEFEELEAYFKEQIGKDLPEEIKVEL 622
W ++ +E+ + +EQ+G DLP+EI+ E+
Sbjct: 581 WTNDAKEIRKFLEEQVGPDLPKEIRAEM 608
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,257,389
Number of Sequences: 369166
Number of extensions: 1583067
Number of successful extensions: 4985
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4613
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4885
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6170718545
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)