Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_O08
(736 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P53597|SUCA_HUMAN Succinyl-CoA ligase [GDP-forming] alph... 230 3e-60
sp|P13086|SUCA_RAT Succinyl-CoA ligase [GDP-forming] alpha-... 226 4e-59
sp|P53596|SUCA_CAEEL Probable succinyl-CoA ligase [GDP-form... 225 1e-58
sp|Q9WUM5|SUCA_MOUSE Succinyl-CoA ligase [GDP-forming] alph... 223 5e-58
sp|Q94522|SUCA_DROME Succinyl-CoA ligase [GDP-forming] alph... 216 5e-56
sp|P36967|SUCA_DICDI Succinyl-CoA ligase [GDP-forming] alph... 201 2e-51
sp|Q8LAD2|SUCA2_ARATH Succinyl-CoA ligase [GDP-forming] alp... 196 4e-50
sp|P68209|SUCA1_ARATH Succinyl-CoA ligase [GDP-forming] alp... 194 2e-49
sp|O13750|SUCA_SCHPO Probable succinyl-CoA ligase [GDP-form... 189 7e-48
sp|O08371|SUCD_RICPR Succinyl-CoA synthetase alpha chain (S... 185 1e-46
>sp|P53597|SUCA_HUMAN Succinyl-CoA ligase [GDP-forming] alpha-chain, mitochondrial
precursor (Succinyl-CoA synthetase, alpha chain)
(SCS-alpha)
Length = 333
Score = 230 bits (586), Expect = 3e-60
Identities = 110/185 (59%), Positives = 135/185 (72%)
Frame = +3
Query: 9 RLINQEKTRLIGPNCPGIIKPNQCKIGIMPAHIHKPGKIGIVSRSGTLTYEAVHQTSQVG 188
+L+ QEKTRLIGPNCPG+I P +CKIGIMP HIHK G+IGIVSRSGTLTYEAVHQT+QVG
Sbjct: 145 KLLRQEKTRLIGPNCPGVINPGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVG 204
Query: 189 LGQSLVIGIGGDPFNGTNFVDCLEVFVRDEHTKXXXXXXXXXXXXXXXXXMYLEKHNAGP 368
LGQSL +GIGGDPFNGT+F+DCLE+F+ D T+ +L++HN+GP
Sbjct: 205 LGQSLCVGIGGDPFNGTDFIDCLEIFLNDSATEGIILIGEIGGNAEENAAEFLKQHNSGP 264
Query: 369 NRKAVVSFIAGLTAPPGRRMXXXXXXXXXXXXXXQEKIDALKHAGVIVTLSPAQMGASMI 548
N K VVSFIAGLTAPPGRRM +EKI AL+ AGV+V++SPAQ+G ++
Sbjct: 265 NSKPVVSFIAGLTAPPGRRMGHAGAIIAGGKGGAKEKISALQSAGVVVSMSPAQLGTTIY 324
Query: 549 EALHK 563
+ K
Sbjct: 325 KEFEK 329
>sp|P13086|SUCA_RAT Succinyl-CoA ligase [GDP-forming] alpha-chain, mitochondrial
precursor (Succinyl-CoA synthetase, alpha chain)
(SCS-alpha)
Length = 333
Score = 226 bits (577), Expect = 4e-59
Identities = 112/185 (60%), Positives = 132/185 (71%)
Frame = +3
Query: 9 RLINQEKTRLIGPNCPGIIKPNQCKIGIMPAHIHKPGKIGIVSRSGTLTYEAVHQTSQVG 188
+L Q KTRLIGPNCPGII P +CKIGIMP HIHK G+IGIVSRSGTLTYEAVHQT+QVG
Sbjct: 145 KLTRQGKTRLIGPNCPGIINPGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVG 204
Query: 189 LGQSLVIGIGGDPFNGTNFVDCLEVFVRDEHTKXXXXXXXXXXXXXXXXXMYLEKHNAGP 368
LGQSL IGIGGDPFNGTNF+DCL+VF++D T+ +L++HN+GP
Sbjct: 205 LGQSLCIGIGGDPFNGTNFIDCLDVFLKDPATEGIVLIGEIGGHAEENAAEFLKEHNSGP 264
Query: 369 NRKAVVSFIAGLTAPPGRRMXXXXXXXXXXXXXXQEKIDALKHAGVIVTLSPAQMGASMI 548
K VVSFIAG+TAPPGRRM +EKI AL+ AGVIV++SPAQ+G M
Sbjct: 265 KAKPVVSFIAGITAPPGRRMGHAGAIIAGGKGGAKEKISALQSAGVIVSMSPAQLGTCMY 324
Query: 549 EALHK 563
+ K
Sbjct: 325 KEFEK 329
>sp|P53596|SUCA_CAEEL Probable succinyl-CoA ligase [GDP-forming] alpha-chain,
mitochondrial precursor (Succinyl-CoA synthetase, alpha
chain) (SCS-alpha)
Length = 322
Score = 225 bits (573), Expect = 1e-58
Identities = 111/184 (60%), Positives = 131/184 (71%)
Frame = +3
Query: 3 RTRLINQEKTRLIGPNCPGIIKPNQCKIGIMPAHIHKPGKIGIVSRSGTLTYEAVHQTSQ 182
++RL+ Q KTRL+GPNCPGII +QCKIGIMP HIHK G IGIVSRSGTLTYEAVHQT+Q
Sbjct: 134 KSRLLKQNKTRLVGPNCPGIISADQCKIGIMPGHIHKRGCIGIVSRSGTLTYEAVHQTTQ 193
Query: 183 VGLGQSLVIGIGGDPFNGTNFVDCLEVFVRDEHTKXXXXXXXXXXXXXXXXXMYLEKHNA 362
VG GQ+L +GIGGDPFNGTNF+DCL VF+ D TK YL++HN+
Sbjct: 194 VGFGQTLCVGIGGDPFNGTNFIDCLNVFLEDPETKGIILIGEIGGSAEEEAAAYLKEHNS 253
Query: 363 GPNRKAVVSFIAGLTAPPGRRMXXXXXXXXXXXXXXQEKIDALKHAGVIVTLSPAQMGAS 542
G NRK VVSFIAG+TAPPGRRM +KI+AL+ AGV+VT SPA++G S
Sbjct: 254 GANRKPVVSFIAGVTAPPGRRMGHAGAIISGGKGTAADKINALREAGVVVTDSPAKLGTS 313
Query: 543 MIEA 554
M A
Sbjct: 314 MATA 317
>sp|Q9WUM5|SUCA_MOUSE Succinyl-CoA ligase [GDP-forming] alpha-chain, mitochondrial
precursor (Succinyl-CoA synthetase, alpha chain)
(SCS-alpha)
Length = 333
Score = 223 bits (567), Expect = 5e-58
Identities = 109/185 (58%), Positives = 131/185 (70%)
Frame = +3
Query: 9 RLINQEKTRLIGPNCPGIIKPNQCKIGIMPAHIHKPGKIGIVSRSGTLTYEAVHQTSQVG 188
RL Q TRLIGPNCPG+I P +CKIGIMP HIHK G+IGIVSRSGTLTYEAVHQT+QVG
Sbjct: 145 RLTRQGTTRLIGPNCPGVINPGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVG 204
Query: 189 LGQSLVIGIGGDPFNGTNFVDCLEVFVRDEHTKXXXXXXXXXXXXXXXXXMYLEKHNAGP 368
LGQSL IGIGGDPFNGT+F+DCLEVF+ D T+ +L++HN+GP
Sbjct: 205 LGQSLCIGIGGDPFNGTDFIDCLEVFLNDPATEGIILIGEIGGHAEENAAAFLKEHNSGP 264
Query: 369 NRKAVVSFIAGLTAPPGRRMXXXXXXXXXXXXXXQEKIDALKHAGVIVTLSPAQMGASMI 548
K VVSFIAG+TAPPGRRM +EKI AL+ AGV+V++SPAQ+G ++
Sbjct: 265 KAKPVVSFIAGITAPPGRRMGHAGAIIAGGKGGAKEKISALQSAGVVVSMSPAQLGTTIY 324
Query: 549 EALHK 563
+ K
Sbjct: 325 KEFEK 329
>sp|Q94522|SUCA_DROME Succinyl-CoA ligase [GDP-forming] alpha-chain, mitochondrial
precursor (Succinyl-CoA synthetase, alpha chain)
(SCS-alpha)
Length = 328
Score = 216 bits (550), Expect = 5e-56
Identities = 107/185 (57%), Positives = 131/185 (70%)
Frame = +3
Query: 12 LINQEKTRLIGPNCPGIIKPNQCKIGIMPAHIHKPGKIGIVSRSGTLTYEAVHQTSQVGL 191
LI+Q K+RL+GPNCPGII P QCKIGIMP HIHK GKIG+VSRSGTLTYEAVHQT++VGL
Sbjct: 141 LISQSKSRLVGPNCPGIIAPEQCKIGIMPGHIHKRGKIGVVSRSGTLTYEAVHQTTEVGL 200
Query: 192 GQSLVIGIGGDPFNGTNFVDCLEVFVRDEHTKXXXXXXXXXXXXXXXXXMYLEKHNAGPN 371
GQ+L +GIGGDPFNGT+F+DCLEVF++D TK YL ++N+G
Sbjct: 201 GQTLCVGIGGDPFNGTDFIDCLEVFLKDPETKGIILIGEIGGVAEEKAADYLTEYNSGIK 260
Query: 372 RKAVVSFIAGLTAPPGRRMXXXXXXXXXXXXXXQEKIDALKHAGVIVTLSPAQMGASMIE 551
K VVSFIAG++APPGRRM +KI AL+ AGVIVT SPA+MG + +
Sbjct: 261 AKPVVSFIAGVSAPPGRRMGHAGAIISGGKGGANDKIAALEKAGVIVTRSPAKMGHELFK 320
Query: 552 ALHKL 566
+ +L
Sbjct: 321 EMKRL 325
>sp|P36967|SUCA_DICDI Succinyl-CoA ligase [GDP-forming] alpha-chain, mitochondrial
precursor (Succinyl-CoA synthetase, alpha chain)
(SCS-alpha)
Length = 310
Score = 201 bits (511), Expect = 2e-51
Identities = 105/179 (58%), Positives = 121/179 (67%)
Frame = +3
Query: 12 LINQEKTRLIGPNCPGIIKPNQCKIGIMPAHIHKPGKIGIVSRSGTLTYEAVHQTSQVGL 191
L Q KTRLIGPNCPGIIKP +CKIGIMP HIHKPGKIGIVSRSGTLTYEAV QT+ VGL
Sbjct: 131 LNKQNKTRLIGPNCPGIIKPGECKIGIMPGHIHKPGKIGIVSRSGTLTYEAVAQTTAVGL 190
Query: 192 GQSLVIGIGGDPFNGTNFVDCLEVFVRDEHTKXXXXXXXXXXXXXXXXXMYLEKHNAGPN 371
GQS IGIGGDPFNGTNF+DCL++F +D T+ +L + P
Sbjct: 191 GQSTCIGIGGDPFNGTNFIDCLKMFTQDPQTEGIILIGEIGGEAEEEAAQWLIDN---PT 247
Query: 372 RKAVVSFIAGLTAPPGRRMXXXXXXXXXXXXXXQEKIDALKHAGVIVTLSPAQMGASMI 548
K VVSFIAGL+APPGRRM KI+ALK AGV VT SPA++G +++
Sbjct: 248 DKPVVSFIAGLSAPPGRRMGHAGAIISGGKGDANSKIEALKAAGVTVTFSPAKLGETIL 306
>sp|Q8LAD2|SUCA2_ARATH Succinyl-CoA ligase [GDP-forming] alpha-chain 2, mitochondrial
precursor (Succinyl-CoA synthetase 2, alpha chain)
(SCS2-alpha)
Length = 341
Score = 196 bits (499), Expect = 4e-50
Identities = 104/183 (56%), Positives = 122/183 (66%)
Frame = +3
Query: 3 RTRLINQEKTRLIGPNCPGIIKPNQCKIGIMPAHIHKPGKIGIVSRSGTLTYEAVHQTSQ 182
+ L +Q KTRLIGPNCPGIIKP +CKIGIMP +IHKPGKIGIVSRSGTLTYEAV QT+
Sbjct: 153 KAALNSQSKTRLIGPNCPGIIKPGECKIGIMPGYIHKPGKIGIVSRSGTLTYEAVFQTTA 212
Query: 183 VGLGQSLVIGIGGDPFNGTNFVDCLEVFVRDEHTKXXXXXXXXXXXXXXXXXMYLEKHNA 362
VGLGQS +GIGGDPFNGTNFVDCLE F D T+ ++++
Sbjct: 213 VGLGQSTCVGIGGDPFNGTNFVDCLEKFFVDPQTEGIVLIGEIGGTAEEDAAALIKENGT 272
Query: 363 GPNRKAVVSFIAGLTAPPGRRMXXXXXXXXXXXXXXQEKIDALKHAGVIVTLSPAQMGAS 542
K VV+FIAGLTAPPGRRM Q+KI +L+ AGV V SPA++GA+
Sbjct: 273 D---KPVVAFIAGLTAPPGRRMGHAGAIVSGGKGTAQDKIKSLRDAGVKVVESPAKIGAA 329
Query: 543 MIE 551
M E
Sbjct: 330 MFE 332
>sp|P68209|SUCA1_ARATH Succinyl-CoA ligase [GDP-forming] alpha-chain 1, mitochondrial
precursor (Succinyl-CoA synthetase 1, alpha chain)
(SCS1-alpha)
Length = 347
Score = 194 bits (493), Expect = 2e-49
Identities = 104/180 (57%), Positives = 119/180 (66%)
Frame = +3
Query: 12 LINQEKTRLIGPNCPGIIKPNQCKIGIMPAHIHKPGKIGIVSRSGTLTYEAVHQTSQVGL 191
L +Q KTRLIGPNCPGIIKP +CKIGIMP +IHKPGKIGIVSRSGTLTYEAV QT+ VGL
Sbjct: 161 LNSQSKTRLIGPNCPGIIKPGECKIGIMPGYIHKPGKIGIVSRSGTLTYEAVFQTTAVGL 220
Query: 192 GQSLVIGIGGDPFNGTNFVDCLEVFVRDEHTKXXXXXXXXXXXXXXXXXMYLEKHNAGPN 371
GQS +GIGGDPFNGTNFVDCLE F D T+ ++ A
Sbjct: 221 GQSTCVGIGGDPFNGTNFVDCLEKFFVDPQTEGIVLIGEIGGTAEEDAAALIK---ASGT 277
Query: 372 RKAVVSFIAGLTAPPGRRMXXXXXXXXXXXXXXQEKIDALKHAGVIVTLSPAQMGASMIE 551
K VV+FIAGLTAPPGRRM Q+KI +L AGV V SPA++G++M E
Sbjct: 278 EKPVVAFIAGLTAPPGRRMGHAGAIVSGGKGTAQDKIKSLNDAGVKVVESPAKIGSAMYE 337
>sp|O13750|SUCA_SCHPO Probable succinyl-CoA ligase [GDP-forming] alpha-chain,
mitochondrial precursor (Succinyl-CoA synthetase, alpha
chain) (SCS-alpha)
Length = 331
Score = 189 bits (480), Expect = 7e-48
Identities = 100/188 (53%), Positives = 125/188 (66%), Gaps = 1/188 (0%)
Frame = +3
Query: 12 LINQEKTRLIGPNCPGIIKPNQCKIGIMPAHIHKPGKIGIVSRSGTLTYEAVHQTSQVGL 191
L Q K+RL+GPNCPGII+P QCKIGIMP+HIHKPG IGIVSRSGTLTYEAV+QT+Q L
Sbjct: 144 LKTQSKSRLVGPNCPGIIRPGQCKIGIMPSHIHKPGCIGIVSRSGTLTYEAVNQTTQTDL 203
Query: 192 GQSLVIGIGGDPFNGTNFVDCLEVFVRDEHTKXXXXXXXXXXXXXXXXXMYLEKHNAGPN 371
GQSLVIGIGGDPF GTNF+D L++F+ D +T+ ++ NA +
Sbjct: 204 GQSLVIGIGGDPFPGTNFIDALKLFLDDPNTQGIILIGEIGGSAEEDAAEFIRAANASRS 263
Query: 372 R-KAVVSFIAGLTAPPGRRMXXXXXXXXXXXXXXQEKIDALKHAGVIVTLSPAQMGASMI 548
K VVSFIAG TAP GRRM K +AL+ AGV ++ SPA +G+ ++
Sbjct: 264 TPKPVVSFIAGATAPKGRRMGHAGAIVAGGKGTAAAKFEALEAAGVRISRSPATLGSLIV 323
Query: 549 EALHKLSN 572
E L+KL +
Sbjct: 324 EELNKLKH 331
>sp|O08371|SUCD_RICPR Succinyl-CoA synthetase alpha chain (SCS-alpha)
Length = 292
Score = 185 bits (469), Expect = 1e-46
Identities = 92/186 (49%), Positives = 123/186 (66%)
Frame = +3
Query: 9 RLINQEKTRLIGPNCPGIIKPNQCKIGIMPAHIHKPGKIGIVSRSGTLTYEAVHQTSQVG 188
R + KTRLIGPNCPG+I P +CKIGIMP HIHK G IGIVSRSGTLTYEAV QT+ G
Sbjct: 110 RALIGSKTRLIGPNCPGVITPGECKIGIMPGHIHKIGDIGIVSRSGTLTYEAVAQTTAAG 169
Query: 189 LGQSLVIGIGGDPFNGTNFVDCLEVFVRDEHTKXXXXXXXXXXXXXXXXXMYLEKHNAGP 368
LGQS +GIGGDP NGT+FVDC+E+F++D+ TK ++++
Sbjct: 170 LGQSTCVGIGGDPVNGTSFVDCIEMFLQDDETKAIIMIGEIGGSAEEDAADFIKQSKI-- 227
Query: 369 NRKAVVSFIAGLTAPPGRRMXXXXXXXXXXXXXXQEKIDALKHAGVIVTLSPAQMGASMI 548
+K +VSFIAG+TAP +RM ++K++ L+ AGVI+T SPA +G +M+
Sbjct: 228 -KKPIVSFIAGITAPADKRMGHAGAIISGGKGSAEDKVEVLQSAGVIITRSPADIGKTML 286
Query: 549 EALHKL 566
+ L+K+
Sbjct: 287 DLLNKI 292
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,575,395
Number of Sequences: 369166
Number of extensions: 1656913
Number of successful extensions: 3789
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3642
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3744
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6582889600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)