Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_M11
(576 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P63025|VAMP3_RAT Vesicle-associated membrane protein 3 (... 82 1e-15
sp|Q15836|VAM3_HUMAN Vesicle-associated membrane protein 3 ... 81 2e-15
sp|P47193|VAMP2_XENLA Vesicle-associated membrane protein 2... 80 4e-15
sp|Q27236|SYBL_SCHMA Synaptobrevin-like protein 80 5e-15
sp|P63026|VAMP2_BOVIN Vesicle-associated membrane protein 2... 78 2e-14
sp|P63045|VAMP2_RAT Vesicle-associated membrane protein 2 (... 78 2e-14
sp|Q62442|VAMP1_MOUSE Vesicle-associated membrane protein 1... 75 9e-14
sp|P13701|SYB_TORCA Synaptobrevin (Synaptic vesicle-associa... 74 2e-13
sp|P47194|SYB_LOLPE Synaptobrevin 74 2e-13
sp|P23763|VAM1_HUMAN Vesicle-associated membrane protein 1 ... 74 3e-13
>sp|P63025|VAMP3_RAT Vesicle-associated membrane protein 3 (VAMP-3) (Synaptobrevin-3)
(Cellubrevin) (CEB)
sp|P63024|VAMP3_MOUSE Vesicle-associated membrane protein 3 (VAMP-3) (Synaptobrevin-3)
(Cellubrevin) (CEB)
Length = 103
Score = 82.0 bits (201), Expect = 1e-15
Identities = 37/75 (49%), Positives = 51/75 (68%)
Frame = +2
Query: 53 SSYGYQSNPKLKNVQQQVDQLTDSMRKNMDKVLERDKNLDDLNVRAQDMEGNAREFHASA 232
SS SN +L+ Q QVD++ D MR N+DKVLERD+ L +L+ RA ++ A +F SA
Sbjct: 9 SSAATGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSA 68
Query: 233 VKARRKFWWQNMKMW 277
K +RK+WW+N KMW
Sbjct: 69 AKLKRKYWWKNCKMW 83
>sp|Q15836|VAM3_HUMAN Vesicle-associated membrane protein 3 (VAMP-3) (Synaptobrevin 3)
(Cellubrevin) (CEB)
Length = 100
Score = 81.3 bits (199), Expect = 2e-15
Identities = 35/69 (50%), Positives = 49/69 (71%)
Frame = +2
Query: 71 SNPKLKNVQQQVDQLTDSMRKNMDKVLERDKNLDDLNVRAQDMEGNAREFHASAVKARRK 250
SN +L+ Q QVD++ D MR N+DKVLERD+ L +L+ RA ++ A +F SA K +RK
Sbjct: 11 SNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRK 70
Query: 251 FWWQNMKMW 277
+WW+N KMW
Sbjct: 71 YWWKNCKMW 79
>sp|P47193|VAMP2_XENLA Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
(SYBII)
Length = 114
Score = 80.1 bits (196), Expect = 4e-15
Identities = 37/77 (48%), Positives = 50/77 (64%)
Frame = +2
Query: 44 APNSSYGYQSNPKLKNVQQQVDQLTDSMRKNMDKVLERDKNLDDLNVRAQDMEGNAREFH 223
AP SN +L+ Q QVD++ D MR N+DKVLERD L +L+ RA ++ A +F
Sbjct: 17 APQGPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDTKLSELDDRADALQAGASQFE 76
Query: 224 ASAVKARRKFWWQNMKM 274
SA K +RK+WW+NMKM
Sbjct: 77 TSAAKLKRKYWWKNMKM 93
>sp|Q27236|SYBL_SCHMA Synaptobrevin-like protein
Length = 131
Score = 79.7 bits (195), Expect = 5e-15
Identities = 36/69 (52%), Positives = 51/69 (73%)
Frame = +2
Query: 68 QSNPKLKNVQQQVDQLTDSMRKNMDKVLERDKNLDDLNVRAQDMEGNAREFHASAVKARR 247
++N +L+ Q QV+++ D MR N+DKVLERDKNL +L+ RA ++ A +F ASA K +R
Sbjct: 14 KTNKRLQQTQAQVNEVVDIMRVNVDKVLERDKNLSELDGRADALQAGASQFEASAGKLKR 73
Query: 248 KFWWQNMKM 274
KFWW+N KM
Sbjct: 74 KFWWKNCKM 82
>sp|P63026|VAMP2_BOVIN Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
sp|P63027|VAM2_HUMAN Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin 2)
Length = 116
Score = 77.8 bits (190), Expect = 2e-14
Identities = 34/68 (50%), Positives = 49/68 (72%)
Frame = +2
Query: 71 SNPKLKNVQQQVDQLTDSMRKNMDKVLERDKNLDDLNVRAQDMEGNAREFHASAVKARRK 250
SN +L+ Q QVD++ D MR N+DKVLERD+ L +L+ RA ++ A +F SA K +RK
Sbjct: 28 SNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRK 87
Query: 251 FWWQNMKM 274
+WW+N+KM
Sbjct: 88 YWWKNLKM 95
>sp|P63045|VAMP2_RAT Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
sp|P63044|VAMP2_MOUSE Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Length = 116
Score = 77.8 bits (190), Expect = 2e-14
Identities = 34/68 (50%), Positives = 49/68 (72%)
Frame = +2
Query: 71 SNPKLKNVQQQVDQLTDSMRKNMDKVLERDKNLDDLNVRAQDMEGNAREFHASAVKARRK 250
SN +L+ Q QVD++ D MR N+DKVLERD+ L +L+ RA ++ A +F SA K +RK
Sbjct: 28 SNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRK 87
Query: 251 FWWQNMKM 274
+WW+N+KM
Sbjct: 88 YWWKNLKM 95
>sp|Q62442|VAMP1_MOUSE Vesicle-associated membrane protein 1 (VAMP-1) (Synaptobrevin-1)
Length = 118
Score = 75.5 bits (184), Expect = 9e-14
Identities = 33/68 (48%), Positives = 49/68 (72%)
Frame = +2
Query: 71 SNPKLKNVQQQVDQLTDSMRKNMDKVLERDKNLDDLNVRAQDMEGNAREFHASAVKARRK 250
SN +L+ Q QV+++ D MR N+DKVLERD+ L +L+ RA ++ A +F +SA K +RK
Sbjct: 30 SNRRLQQTQAQVEEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRK 89
Query: 251 FWWQNMKM 274
+WW+N KM
Sbjct: 90 YWWKNCKM 97
>sp|P13701|SYB_TORCA Synaptobrevin (Synaptic vesicle-associated integral membrane
protein) (VAMP-1)
Length = 120
Score = 74.3 bits (181), Expect = 2e-13
Identities = 33/76 (43%), Positives = 51/76 (67%)
Frame = +2
Query: 47 PNSSYGYQSNPKLKNVQQQVDQLTDSMRKNMDKVLERDKNLDDLNVRAQDMEGNAREFHA 226
P + SN +L+ Q QV+++ D +R N+DKVLERD+ L +L+ RA ++ A +F +
Sbjct: 24 PGAPPNTTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADALQAGASQFES 83
Query: 227 SAVKARRKFWWQNMKM 274
SA K +RK+WW+N KM
Sbjct: 84 SAAKLKRKYWWKNCKM 99
>sp|P47194|SYB_LOLPE Synaptobrevin
Length = 125
Score = 74.3 bits (181), Expect = 2e-13
Identities = 33/69 (47%), Positives = 48/69 (69%)
Frame = +2
Query: 68 QSNPKLKNVQQQVDQLTDSMRKNMDKVLERDKNLDDLNVRAQDMEGNAREFHASAVKARR 247
Q + +L+ Q QV+++ D MR N+DKVLERD + +L+ RA ++ A +F ASA K +R
Sbjct: 36 QQSKRLQQTQAQVEEVVDIMRVNVDKVLERDSKISELDDRADALQAGASQFEASAGKLKR 95
Query: 248 KFWWQNMKM 274
KFWW+N KM
Sbjct: 96 KFWWKNCKM 104
>sp|P23763|VAM1_HUMAN Vesicle-associated membrane protein 1 (VAMP-1) (Synaptobrevin 1)
Length = 118
Score = 73.9 bits (180), Expect = 3e-13
Identities = 32/68 (47%), Positives = 49/68 (72%)
Frame = +2
Query: 71 SNPKLKNVQQQVDQLTDSMRKNMDKVLERDKNLDDLNVRAQDMEGNAREFHASAVKARRK 250
SN +L+ Q QV+++ D +R N+DKVLERD+ L +L+ RA ++ A +F +SA K +RK
Sbjct: 30 SNRRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRK 89
Query: 251 FWWQNMKM 274
+WW+N KM
Sbjct: 90 YWWKNCKM 97
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,392,146
Number of Sequences: 369166
Number of extensions: 1004811
Number of successful extensions: 2762
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2680
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2761
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4275400980
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)