Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_L20
(430 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9XSK2|CD63_BOVIN CD63 antigen 45 5e-05
sp|O70401|TSN6_MOUSE Tetraspanin-6 (Tspan-6) (Transmembrane... 43 3e-04
sp|O43657|TSN6_HUMAN Tetraspanin-6 (Tspan-6) (Transmembrane... 40 0.003
sp|P08962|CD63_HUMAN CD63 antigen (Melanoma-associated anti... 38 0.008
sp|P41731|CD63_MOUSE CD63 antigen 37 0.013
sp|O60637|TSN3_HUMAN Tetraspanin-3 (Tspan-3) (Transmembrane... 37 0.017
sp|Q9QY33|TSN3_MOUSE Tetraspanin-3 (Tspan-3) (Transmembrane... 37 0.017
sp|P28648|CD63_RAT CD63 antigen (AD1 antigen) 37 0.023
sp|Q62283|TSN7_MOUSE Tetraspanin-7 (Tspan-7) (Transmembrane... 35 0.050
sp|Q28709|CD63_RABIT CD63 antigen 35 0.050
>sp|Q9XSK2|CD63_BOVIN CD63 antigen
Length = 237
Score = 45.4 bits (106), Expect = 5e-05
Identities = 21/77 (27%), Positives = 41/77 (53%), Gaps = 9/77 (11%)
Frame = +3
Query: 15 IDELQNHFACCGSNSFSDWNSTVFYSNSTNYPSSC-----YSLGGSF----LHTAGCRSK 167
+D++Q F CCG+ +++DW + +N P SC ++ G +F +HT GC K
Sbjct: 136 LDKMQKDFECCGAANYTDWEKILAVTNKV--PDSCCVNITHNCGINFVVKDIHTEGCVEK 193
Query: 168 LYDWYRRFFIAILSVPI 218
+ W R+ + +++ +
Sbjct: 194 IAAWLRKNVLVVVAAAL 210
>sp|O70401|TSN6_MOUSE Tetraspanin-6 (Tspan-6) (Transmembrane 4 superfamily member 6)
Length = 245
Score = 42.7 bits (99), Expect = 3e-04
Identities = 17/45 (37%), Positives = 26/45 (57%)
Frame = +3
Query: 6 SRDIDELQNHFACCGSNSFSDWNSTVFYSNSTNYPSSCYSLGGSF 140
S +D++Q+ CCG ++ DW T +YS T +P SC L G +
Sbjct: 141 SEAVDKIQSTLHCCGVTNYGDWKGTNYYS-ETGFPKSCCKLEGCY 184
>sp|O43657|TSN6_HUMAN Tetraspanin-6 (Tspan-6) (Transmembrane 4 superfamily member 6)
(T245 protein) (Tetraspanin TM4-D) (A15 homolog)
Length = 245
Score = 39.7 bits (91), Expect = 0.003
Identities = 16/41 (39%), Positives = 22/41 (53%)
Frame = +3
Query: 6 SRDIDELQNHFACCGSNSFSDWNSTVFYSNSTNYPSSCYSL 128
S +D++QN CCG + DW T +YS +P SC L
Sbjct: 141 SHAVDKIQNTLHCCGVTDYRDWTDTNYYSEK-GFPKSCCKL 180
>sp|P08962|CD63_HUMAN CD63 antigen (Melanoma-associated antigen ME491)
(Lysosome-associated membrane glycoprotein 3) (LAMP-3)
(Ocular melanoma-associated antigen) (OMA81H)
(Granulophysin) (Tetraspanin-30) (Tspan-30)
Length = 238
Score = 38.1 bits (87), Expect = 0.008
Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 8/76 (10%)
Frame = +3
Query: 15 IDELQNHFACCGSNSFSDWNSTVFYSNSTNYPSSCYSL----GGSF----LHTAGCRSKL 170
+D +Q F CCG+ +++DW S + S C ++ G +F +H GC K+
Sbjct: 136 LDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNEKAIHKEGCVEKI 195
Query: 171 YDWYRRFFIAILSVPI 218
W R+ + + + +
Sbjct: 196 GGWLRKNVLVVAAAAL 211
>sp|P41731|CD63_MOUSE CD63 antigen
Length = 238
Score = 37.4 bits (85), Expect = 0.013
Identities = 18/76 (23%), Positives = 36/76 (47%), Gaps = 8/76 (10%)
Frame = +3
Query: 15 IDELQNHFACCGSNSFSDWNSTVFYSNSTNYPSSCYSL----GGSF----LHTAGCRSKL 170
+D+LQ CCG+++++DW + + S C ++ G F +HT GC +
Sbjct: 136 LDKLQKENNCCGASNYTDWENIPGMAKDRVPDSCCINITVGCGNDFKESTIHTQGCVETI 195
Query: 171 YDWYRRFFIAILSVPI 218
W R+ + + + +
Sbjct: 196 AIWLRKNILLVAAAAL 211
>sp|O60637|TSN3_HUMAN Tetraspanin-3 (Tspan-3) (Transmembrane 4 superfamily member 8)
(Tetraspanin TM4-A)
Length = 253
Score = 37.0 bits (84), Expect = 0.017
Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Frame = +3
Query: 6 SRDIDELQNHFACCGSNSFSDWNSTVFYSNSTN--YPSSC 119
SR ID +Q CCG +++SDW +T ++ + N P SC
Sbjct: 135 SRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSC 174
>sp|Q9QY33|TSN3_MOUSE Tetraspanin-3 (Tspan-3) (Transmembrane 4 superfamily member 8)
(Tetraspanin TM4-A) (OSP-associated protein 1) (OAP-1)
Length = 253
Score = 37.0 bits (84), Expect = 0.017
Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Frame = +3
Query: 6 SRDIDELQNHFACCGSNSFSDWNSTVFYSNSTN--YPSSC 119
SR ID +Q CCG +++SDW +T ++ + N P SC
Sbjct: 135 SRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSC 174
>sp|P28648|CD63_RAT CD63 antigen (AD1 antigen)
Length = 238
Score = 36.6 bits (83), Expect = 0.023
Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 8/66 (12%)
Frame = +3
Query: 15 IDELQNHFACCGSNSFSDWNSTVFYSNSTNYPSSCYSL----GGSF----LHTAGCRSKL 170
+D+LQ CCG+++++DW + S C ++ G F +HT GC +
Sbjct: 136 LDKLQKENKCCGASNYTDWERIPGMAKDRVPDSCCINITVGCGNDFKESTIHTQGCVETI 195
Query: 171 YDWYRR 188
W R+
Sbjct: 196 AAWLRK 201
>sp|Q62283|TSN7_MOUSE Tetraspanin-7 (Tspan-7) (Transmembrane 4 superfamily member 2)
(Cell surface glycoprotein A15) (PE31) (TALLA homolog)
Length = 249
Score = 35.4 bits (80), Expect = 0.050
Identities = 12/38 (31%), Positives = 24/38 (63%)
Frame = +3
Query: 6 SRDIDELQNHFACCGSNSFSDWNSTVFYSNSTNYPSSC 119
SR +D +Q +CCG ++++W+S+ ++ + PS C
Sbjct: 138 SRAVDHVQRSLSCCGVQNYTNWSSSPYFLDHGIPPSCC 175
>sp|Q28709|CD63_RABIT CD63 antigen
Length = 238
Score = 35.4 bits (80), Expect = 0.050
Identities = 19/77 (24%), Positives = 35/77 (45%), Gaps = 9/77 (11%)
Frame = +3
Query: 15 IDELQNHFACCGSNSFSDWNSTVFYSNSTNYPSSC-----YSLGGSF----LHTAGCRSK 167
+D +Q F CCG+ +++DW +T+ P SC G F ++ GC K
Sbjct: 136 LDRMQKDFTCCGAANYTDW-ATIPGMTRDRVPDSCCVNVTSGCGVKFNVKDIYVEGCVEK 194
Query: 168 LYDWYRRFFIAILSVPI 218
+ W R+ + + + +
Sbjct: 195 IGLWLRKNVLVVAAAAL 211
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,714,727
Number of Sequences: 369166
Number of extensions: 909387
Number of successful extensions: 2445
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2397
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2441
length of database: 68,354,980
effective HSP length: 100
effective length of database: 49,881,480
effective search space used: 2095022160
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)