Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_J13
(747 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9CZE3|RAB32_MOUSE Ras-related protein Rab-32 251 1e-66
sp|Q13637|RAB32_HUMAN Ras-related protein Rab-32 251 1e-66
sp|Q8QZZ8|RAB38_MOUSE Ras-related protein Rab-38 241 2e-63
sp|P57729|RAB38_HUMAN Ras-related protein Rab-38 (Antigen N... 239 6e-63
sp|Q91YQ1|RAB7L_MOUSE Ras-related protein Rab-7L1 (Rab-7-li... 195 9e-50
sp|O14966|RAB7L_HUMAN Ras-related protein Rab-7L1 (Rab-7-li... 195 1e-49
sp|O94655|YPT7_SCHPO Ras-related protein ypt7 131 2e-30
sp|Q15286|RAB35_HUMAN Ras-related protein Rab-35 (Rab-1C) (... 124 3e-28
sp|Q9C2L8|RAB7_NEUCR Probable Ras-related protein Rab7 122 8e-28
sp|P61027|RAB10_MOUSE Ras-related protein Rab-10 >gi|465776... 122 1e-27
>sp|Q9CZE3|RAB32_MOUSE Ras-related protein Rab-32
Length = 223
Score = 251 bits (642), Expect = 1e-66
Identities = 129/207 (62%), Positives = 156/207 (75%), Gaps = 1/207 (0%)
Frame = +1
Query: 22 KEYLFKVLVICELGAGKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQLWD 201
+E+LFKVLVI ELG GKTSIIKRYVH+ FSQHYRATIGVDFALKVL WD ++VRLQLWD
Sbjct: 20 REHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWD 79
Query: 202 IAGQERFGNMLRVYYKDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCILL 381
IAGQERFGNM RVYYK+A+GAF+V+D++R+STF+AV+KWK DLDSKV PNG PIP +LL
Sbjct: 80 IAGQERFGNMTRVYYKEALGAFVVFDISRSSTFDAVLKWKNDLDSKVHLPNGSPIPAVLL 139
Query: 382 GNKSDCEREGRLSDTNYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKMLKISLG-P 558
NK D +++ S + +DQF +HGF F+TSAK+NI IDEA LV+ ML P
Sbjct: 140 ANKCDQKKDNSQSPSQ-MDQFCKDHGFTGWFETSAKDNINIDEATRFLVENMLANQQSFP 198
Query: 559 EIKKDNDLIKLGNQKPADKSSQDSKCC 639
+ D D IKL + P K S+CC
Sbjct: 199 SEEIDLDRIKLVEEPPTTKPR--SQCC 223
>sp|Q13637|RAB32_HUMAN Ras-related protein Rab-32
Length = 225
Score = 251 bits (641), Expect = 1e-66
Identities = 126/206 (61%), Positives = 159/206 (77%)
Frame = +1
Query: 22 KEYLFKVLVICELGAGKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQLWD 201
+E+LFKVLVI ELG GKTSIIKRYVH+ FSQHYRATIGVDFALKVL WD ++VRLQLWD
Sbjct: 22 REHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWD 81
Query: 202 IAGQERFGNMLRVYYKDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCILL 381
IAGQERFGNM RVYYK+A+GAF+V+D++R+STFEAV+KWK DLDSKV PNG PIP +LL
Sbjct: 82 IAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLL 141
Query: 382 GNKSDCEREGRLSDTNYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKMLKISLGPE 561
NK D ++ S + +DQF EHGF F+TSAK+NI I+EAA LV+K+L ++
Sbjct: 142 ANKCDQNKDSSQSPSQ-VDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKIL-VNHQSF 199
Query: 562 IKKDNDLIKLGNQKPADKSSQDSKCC 639
++ND+ K+ + ++ S+CC
Sbjct: 200 PNEENDVDKIKLDQETLRAENKSQCC 225
>sp|Q8QZZ8|RAB38_MOUSE Ras-related protein Rab-38
Length = 211
Score = 241 bits (614), Expect = 2e-63
Identities = 119/177 (67%), Positives = 141/177 (79%)
Frame = +1
Query: 10 QMTEKEYLFKVLVICELGAGKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRL 189
Q KE+L+K+LVI +LG GKTSIIKRYVH+ FS HYRATIGVDFALKVL WD +VVRL
Sbjct: 2 QTPHKEHLYKLLVIGDLGVGKTSIIKRYVHQNFSSHYRATIGVDFALKVLHWDPETVVRL 61
Query: 190 QLWDIAGQERFGNMLRVYYKDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIP 369
QLWDIAGQERFGNM RVYY++AMGAFIV+DVTR +TFEAV KWK DLDSK+T PNG P+
Sbjct: 62 QLWDIAGQERFGNMTRVYYREAMGAFIVFDVTRPATFEAVAKWKNDLDSKLTLPNGKPVS 121
Query: 370 CILLGNKSDCEREGRLSDTNYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKML 540
+LL NK D ++ +++ +DQF EHGFV F+TSAKENI IDEA+ LV +L
Sbjct: 122 VVLLANKCDQGKDVLMNNGLKMDQFCKEHGFVGWFETSAKENINIDEASRCLVKHIL 178
>sp|P57729|RAB38_HUMAN Ras-related protein Rab-38 (Antigen NY-MEL-1)
Length = 211
Score = 239 bits (610), Expect = 6e-63
Identities = 118/177 (66%), Positives = 141/177 (79%)
Frame = +1
Query: 10 QMTEKEYLFKVLVICELGAGKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRL 189
Q KE+L+K+LVI +LG GKTSIIKRYVH+ FS HYRATIGVDFALKVL WD +VVRL
Sbjct: 2 QAPHKEHLYKLLVIGDLGVGKTSIIKRYVHQNFSSHYRATIGVDFALKVLHWDPETVVRL 61
Query: 190 QLWDIAGQERFGNMLRVYYKDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIP 369
QLWDIAGQERFGNM RVYY++AMGAFIV+DVTR +TFEAV KWK DLDSK++ PNG P+
Sbjct: 62 QLWDIAGQERFGNMTRVYYREAMGAFIVFDVTRPATFEAVAKWKNDLDSKLSLPNGKPVS 121
Query: 370 CILLGNKSDCEREGRLSDTNYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKML 540
+LL NK D ++ +++ +DQF EHGFV F+TSAKENI IDEA+ LV +L
Sbjct: 122 VVLLANKCDQGKDVLMNNGLKMDQFCKEHGFVGWFETSAKENINIDEASRCLVKHIL 178
>sp|Q91YQ1|RAB7L_MOUSE Ras-related protein Rab-7L1 (Rab-7-like protein 1)
Length = 204
Score = 195 bits (496), Expect = 9e-50
Identities = 95/179 (53%), Positives = 128/179 (71%)
Frame = +1
Query: 13 MTEKEYLFKVLVICELGAGKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQ 192
M +++LFKVLV+ + GKTS+++RY FS+HY++T+GVDFALKVL W DS +VRLQ
Sbjct: 1 MGSRDHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVGVDFALKVLQWSDSEMVRLQ 60
Query: 193 LWDIAGQERFGNMLRVYYKDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPC 372
LWDIAGQERF +M R+YY+DA I++DVT A+TF +WK+DLDSK+T P+G+P+PC
Sbjct: 61 LWDIAGQERFTSMTRLYYRDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPSGEPVPC 120
Query: 373 ILLGNKSDCEREGRLSDTNYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKMLKIS 549
+LL NKSD D +D+F E+GF +TS KEN I+EA LV+KM+ S
Sbjct: 121 LLLANKSDLSPWAVSRD--QIDRFSKENGFTGWTETSVKENKNINEAMRVLVEKMMNNS 177
>sp|O14966|RAB7L_HUMAN Ras-related protein Rab-7L1 (Rab-7-like protein 1)
Length = 203
Score = 195 bits (495), Expect = 1e-49
Identities = 92/179 (51%), Positives = 128/179 (71%)
Frame = +1
Query: 13 MTEKEYLFKVLVICELGAGKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQ 192
M +++LFKVLV+ + GKTS+++RY FS+HY++T+GVDFALKVL W D +VRLQ
Sbjct: 1 MGSRDHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVGVDFALKVLQWSDYEIVRLQ 60
Query: 193 LWDIAGQERFGNMLRVYYKDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPC 372
LWDIAGQERF +M R+YY+DA I++DVT A+TF +WK+DLDSK+T PNG+P+PC
Sbjct: 61 LWDIAGQERFTSMTRLYYRDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPNGEPVPC 120
Query: 373 ILLGNKSDCEREGRLSDTNYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKMLKIS 549
+LL NK C+ + +D+F E+GF +TS KEN I+EA L++KM++ S
Sbjct: 121 LLLANK--CDLSPWAVSRDQIDRFSKENGFTGWTETSVKENKNINEAMRVLIEKMMRNS 177
>sp|O94655|YPT7_SCHPO Ras-related protein ypt7
Length = 205
Score = 131 bits (330), Expect = 2e-30
Identities = 79/207 (38%), Positives = 115/207 (55%), Gaps = 1/207 (0%)
Frame = +1
Query: 19 EKEYLFKVLVICELGAGKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQLW 198
+K++L KV+++ E G GKTSI+ +YV++ FS+ Y+ATIG DF K + DD VV LQLW
Sbjct: 4 KKKHLLKVIILGESGVGKTSIMNQYVNRKFSKDYKATIGADFLTKEVLVDDK-VVTLQLW 62
Query: 199 DIAGQERFGNMLRVYYKDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCIL 378
D AGQERF ++ +Y+ A +VYDV + +FE + W+ + + + N + P IL
Sbjct: 63 DTAGQERFQSLGVAFYRGADCCVLVYDVNNSKSFETLDSWRDEFLIQASPSNPETFPFIL 122
Query: 379 LGNKSDCEREGRLSDTNYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKMLKISLGP 558
LGNK D E + R+ + F G + F+TSAKE I + EA + L+
Sbjct: 123 LGNKVDVEEQKRMVSKSKALAFCQARGEIPYFETSAKEAINVQEAFETVAKLALENMDSD 182
Query: 559 EIKKD-NDLIKLGNQKPADKSSQDSKC 636
+I D D I L D SQ + C
Sbjct: 183 DIAADFTDPIHL------DMESQKTSC 203
>sp|Q15286|RAB35_HUMAN Ras-related protein Rab-35 (Rab-1C) (GTP-binding protein RAY)
sp|Q5U316|RAB35_RAT Ras-related protein Rab-35
sp|Q6PHN9|RAB35_MOUSE Ras-related protein Rab-35
Length = 201
Score = 124 bits (311), Expect = 3e-28
Identities = 71/209 (33%), Positives = 120/209 (57%), Gaps = 4/209 (1%)
Frame = +1
Query: 25 EYLFKVLVICELGAGKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQLWDI 204
++LFK+L+I + G GK+S++ R+ FS Y TIGVDF ++ + + V +LQ+WD
Sbjct: 6 DHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKV-KLQIWDT 64
Query: 205 AGQERFGNMLRVYYKDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCILLG 384
AGQERF + YY+ G +VYDVT A +F V +W +++ N D + IL+G
Sbjct: 65 AGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQ-----NCDDVCRILVG 119
Query: 385 NKSDCEREGRLSDTNYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKMLKIS----L 552
NK+D + E ++ +T +F + G ++ F+TSAKEN+ ++E N + + +L+
Sbjct: 120 NKND-DPERKVVETEDAYKFAGQMG-IQLFETSAKENVNVEEMFNCITELVLRAKKDNLA 177
Query: 553 GPEIKKDNDLIKLGNQKPADKSSQDSKCC 639
+ ++ ND++KL S + +CC
Sbjct: 178 KQQQQQQNDVVKL-----TKNSKRKKRCC 201
>sp|Q9C2L8|RAB7_NEUCR Probable Ras-related protein Rab7
Length = 205
Score = 122 bits (307), Expect = 8e-28
Identities = 66/186 (35%), Positives = 103/186 (55%)
Frame = +1
Query: 16 TEKEYLFKVLVICELGAGKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQL 195
+ K+ L KV+++ + G GKTS++ +YV+K FS Y+ATIG DF + + DD V +QL
Sbjct: 3 SRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSASYKATIGADFLTREVLVDDRQVT-MQL 61
Query: 196 WDIAGQERFGNMLRVYYKDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCI 375
WD AGQERF ++ +Y+ A +VYDV + +F+A+ W+ + + + + D P +
Sbjct: 62 WDTAGQERFQSLGVAFYRGADCCVLVYDVNNSKSFDALDSWRDEFLIQASPRDPDNFPFV 121
Query: 376 LLGNKSDCEREGRLSDTNYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKMLKISLG 555
+LGNK D E R+ T F G + F+TSAKE I +++A + L
Sbjct: 122 VLGNKIDMEESKRVISTKRAMTFCQSKGNIPYFETSAKEAINVEQAFEVIARNALMQEES 181
Query: 556 PEIKKD 573
E D
Sbjct: 182 EEFSGD 187
>sp|P61027|RAB10_MOUSE Ras-related protein Rab-10
sp|P61026|RAB10_HUMAN Ras-related protein Rab-10
Length = 200
Score = 122 bits (306), Expect = 1e-27
Identities = 75/211 (35%), Positives = 117/211 (55%), Gaps = 2/211 (0%)
Frame = +1
Query: 13 MTEKEY--LFKVLVICELGAGKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVR 186
M +K Y LFK+L+I + G GKT ++ R+ F+ + +TIG+DF +K + + +
Sbjct: 1 MAKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKI-K 59
Query: 187 LQLWDIAGQERFGNMLRVYYKDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPI 366
LQ+WD AGQERF + YY+ AMG +VYD+T +FE + KW +++D + +
Sbjct: 60 LQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHA----NEDV 115
Query: 367 PCILLGNKSDCEREGRLSDTNYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKMLKI 546
+LLGNK D + + R+ +Q EHG ++ F+TSAK NI I++A L + +L+
Sbjct: 116 ERMLLGNKCDMD-DKRVVPKGKGEQIAREHG-IRFFETSAKANINIEKAFLTLAEDILRK 173
Query: 547 SLGPEIKKDNDLIKLGNQKPADKSSQDSKCC 639
+ E +N I G K SKCC
Sbjct: 174 TPVKEPNSENVDISSGGGVTGWK----SKCC 200
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,348,011
Number of Sequences: 369166
Number of extensions: 1732000
Number of successful extensions: 5273
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4772
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4873
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6776504000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)