Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_G23
(822 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O15143|ARC1B_HUMAN Actin-related protein 2/3 complex sub... 130 3e-30
sp|O88656|ARC1B_RAT Actin-related protein 2/3 complex subun... 130 6e-30
sp|Q9WV32|ARC1B_MOUSE Actin-related protein 2/3 complex sub... 125 1e-28
sp|Q9R0Q6|ARC1A_MOUSE Actin-related protein 2/3 complex sub... 120 3e-27
sp|Q92747|ARC1A_HUMAN Actin-related protein 2/3 complex sub... 119 8e-27
sp|Q99PD4|ARC1A_RAT Actin-related protein 2/3 complex subun... 119 1e-26
sp|P78774|ARPC1_SCHPO Probable ARP2/3 complex 41 kDa subuni... 91 3e-18
sp|P38328|ARPC1_YEAST Probable ARP2/3 complex 41 kDa subuni... 67 6e-11
sp|Q91VU6|WDR23_MOUSE WD-repeat protein 23 34 0.42
sp|Q8TEB1|WDR23_HUMAN WD-repeat protein 23 34 0.42
>sp|O15143|ARC1B_HUMAN Actin-related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa
subunit) (p41-ARC)
Length = 372
Score = 130 bits (328), Expect = 3e-30
Identities = 61/192 (31%), Positives = 110/192 (57%), Gaps = 5/192 (2%)
Frame = +2
Query: 11 WGTKLTFNSLLWESEGGLGWIHSIAFSNDGNKLIWSTHSSTICVATVSGSQQPPSVKMIL 190
WG+K+ F L++ES GW+H + FS G+++ W +H ST+C+A + + +V +
Sbjct: 185 WGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLA---DADKKMAVATLA 241
Query: 191 MDNLPFLTLVWAAPNTVIGAGHDCVP--FTISTDKDQLKLGTSLDSKEELNTNATLSAKD 364
+ LP L L + N+++ AGHDC P FT L G LD ++ ++ L+A++
Sbjct: 242 SETLPLLALTFITDNSLVAAGHDCFPVLFTYDAAAGMLSFGGRLDVPKQ-SSQRGLTARE 300
Query: 365 RFRQIDRIATADSNDSI---INSKHKNAINEIRIMKGSNGSAQVLSTIGRDGQLILWDLK 535
RF+ +D+ A+++ + ++S HKN++++I ++ G T G DG + +WD+K
Sbjct: 301 RFQNLDKKASSEGGTAAGAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVK 360
Query: 536 TLSQKMSDLKIQ 571
+L + DLKI+
Sbjct: 361 SLESALKDLKIK 372
>sp|O88656|ARC1B_RAT Actin-related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa
subunit) (p41-ARC)
Length = 372
Score = 130 bits (326), Expect = 6e-30
Identities = 60/192 (31%), Positives = 110/192 (57%), Gaps = 5/192 (2%)
Frame = +2
Query: 11 WGTKLTFNSLLWESEGGLGWIHSIAFSNDGNKLIWSTHSSTICVATVSGSQQPPSVKMIL 190
WG+K+ F L++ES GW+H + FS G+++ W +H ST+C+ +++ +V +
Sbjct: 185 WGSKMPFGELMFESSSSCGWVHGVCFSAGGSRVAWVSHDSTVCLV---DAEKKMAVATLA 241
Query: 191 MDNLPFLTLVWAAPNTVIGAGHDCVP--FTISTDKDQLKLGTSLDSKEELNTNATLSAKD 364
+ LP L + + N+++ AGHDC P FT L G LD ++ N+ L+A++
Sbjct: 242 SETLPLLAITFITENSLVAAGHDCFPVLFTYDNAAGTLSFGGRLDVPKQ-NSQRGLTARE 300
Query: 365 RFRQIDRIATADSNDSI---INSKHKNAINEIRIMKGSNGSAQVLSTIGRDGQLILWDLK 535
RF+ +D+ A+++ + ++S HKN++++I ++ G T G DG + +WD+K
Sbjct: 301 RFQNLDKKASSEGGAATGAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVK 360
Query: 536 TLSQKMSDLKIQ 571
+L + DLKI+
Sbjct: 361 SLESALKDLKIR 372
>sp|Q9WV32|ARC1B_MOUSE Actin-related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa
subunit) (p41-ARC)
Length = 372
Score = 125 bits (315), Expect = 1e-28
Identities = 58/192 (30%), Positives = 109/192 (56%), Gaps = 5/192 (2%)
Frame = +2
Query: 11 WGTKLTFNSLLWESEGGLGWIHSIAFSNDGNKLIWSTHSSTICVATVSGSQQPPSVKMIL 190
WG+K+ F L++ES GW+H + FS G+++ W +H ST+C+ + + +V +
Sbjct: 185 WGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLV---DADKKMAVATLA 241
Query: 191 MDNLPFLTLVWAAPNTVIGAGHDCVP--FTISTDKDQLKLGTSLDSKEELNTNATLSAKD 364
+ LP L + + N+++ AGHDC P FT L G LD ++ ++ ++A++
Sbjct: 242 SETLPLLAVTFITENSLVAAGHDCFPVLFTYDNAAVTLSFGGRLDVPKQ-SSQRGMTARE 300
Query: 365 RFRQIDRIATADSNDSI---INSKHKNAINEIRIMKGSNGSAQVLSTIGRDGQLILWDLK 535
RF+ +D+ A+++ + ++S HKN++++I ++ G T G DG + +WD+K
Sbjct: 301 RFQNLDKKASSEGGAATGAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVK 360
Query: 536 TLSQKMSDLKIQ 571
+L + DLKI+
Sbjct: 361 SLESALKDLKIK 372
>sp|Q9R0Q6|ARC1A_MOUSE Actin-related protein 2/3 complex subunit 1A (SOP2-like protein)
(Sid 329)
Length = 370
Score = 120 bits (302), Expect = 3e-27
Identities = 65/190 (34%), Positives = 106/190 (55%), Gaps = 4/190 (2%)
Frame = +2
Query: 11 WGTKLTFNSLLWE--SEGGLGWIHSIAFSNDGNKLIWSTHSSTICVATVSGSQQPPSVKM 184
WG+K+ F L+ E G GW+H ++FS GN+L W +H ST+ VA S S Q V
Sbjct: 185 WGSKMPFGQLMSEFGGSGTGGWVHGVSFSASGNRLAWVSHDSTVSVADASKSVQ---VST 241
Query: 185 ILMDNLPFLTLVWAAPNTVIGAGHDCVPFTIS-TDKDQLKLGTSLD-SKEELNTNATLSA 358
+ + LP L++ + + N+V+ AGHDC P + D+ L + LD K+ + N +SA
Sbjct: 242 LRTEFLPLLSVSFVSENSVVAAGHDCCPMLFNYDDRGCLTFVSKLDVPKQSIQRN--MSA 299
Query: 359 KDRFRQIDRIATADSNDSIINSKHKNAINEIRIMKGSNGSAQVLSTIGRDGQLILWDLKT 538
+RFR +D+ AT + ++ + + H+N+I ++ I + + T G DG + +WD KT
Sbjct: 300 MERFRNMDKRATTEDRNTALETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKT 359
Query: 539 LSQKMSDLKI 568
L + L+I
Sbjct: 360 LESSIQGLRI 369
>sp|Q92747|ARC1A_HUMAN Actin-related protein 2/3 complex subunit 1A (SOP2-like protein)
Length = 370
Score = 119 bits (299), Expect = 8e-27
Identities = 65/190 (34%), Positives = 107/190 (56%), Gaps = 4/190 (2%)
Frame = +2
Query: 11 WGTKLTFNSLLWE--SEGGLGWIHSIAFSNDGNKLIWSTHSSTICVATVSGSQQPPSVKM 184
WG+K+ F L+ E G GW+H ++FS G++L W +H ST+ VA S S Q ++K
Sbjct: 185 WGSKMPFGQLMSEFGGSGTGGWVHGVSFSASGSRLAWVSHDSTVSVADASKSVQVSTLKT 244
Query: 185 ILMDNLPFLTLVWAAPNTVIGAGHDCVPFT-ISTDKDQLKLGTSLD-SKEELNTNATLSA 358
+ LP L++ + + N+V+ AGHDC P I D+ L + LD K+ + N +SA
Sbjct: 245 ---EFLPLLSVSFVSENSVVAAGHDCCPMLFIYDDRGCLTFVSKLDIPKQSIQRN--MSA 299
Query: 359 KDRFRQIDRIATADSNDSIINSKHKNAINEIRIMKGSNGSAQVLSTIGRDGQLILWDLKT 538
+RFR +D+ AT + ++ + + H+N+I ++ I + + T G DG + +WD KT
Sbjct: 300 MERFRNMDKRATTEDRNTALETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKT 359
Query: 539 LSQKMSDLKI 568
L + L+I
Sbjct: 360 LESSIQGLRI 369
>sp|Q99PD4|ARC1A_RAT Actin-related protein 2/3 complex subunit 1A
Length = 370
Score = 119 bits (297), Expect = 1e-26
Identities = 64/190 (33%), Positives = 106/190 (55%), Gaps = 4/190 (2%)
Frame = +2
Query: 11 WGTKLTFNSLLWE--SEGGLGWIHSIAFSNDGNKLIWSTHSSTICVATVSGSQQPPSVKM 184
WG+K+ F L+ E G GW+H ++FS G++L W +H ST+ VA S S Q V
Sbjct: 185 WGSKMPFGQLMSEFGGSGTGGWVHGVSFSASGSRLAWVSHDSTVSVADASKSVQ---VST 241
Query: 185 ILMDNLPFLTLVWAAPNTVIGAGHDCVPFTIS-TDKDQLKLGTSLD-SKEELNTNATLSA 358
+ + LP L++ + + N+V+ AGHDC P + D+ L + LD K+ + N +SA
Sbjct: 242 LRTEFLPLLSVSFVSENSVVAAGHDCCPMLFNYDDRGCLTFVSKLDVPKQSIQRN--MSA 299
Query: 359 KDRFRQIDRIATADSNDSIINSKHKNAINEIRIMKGSNGSAQVLSTIGRDGQLILWDLKT 538
+RFR +D+ AT + ++ + + H+N+I ++ I + + T G DG + +WD KT
Sbjct: 300 MERFRNMDKRATTEDRNTALETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKT 359
Query: 539 LSQKMSDLKI 568
L + L+I
Sbjct: 360 LESSIQGLRI 369
>sp|P78774|ARPC1_SCHPO Probable ARP2/3 complex 41 kDa subunit (p41-ARC)
Length = 377
Score = 91.3 bits (225), Expect = 3e-18
Identities = 55/193 (28%), Positives = 100/193 (51%), Gaps = 17/193 (8%)
Frame = +2
Query: 5 SNWGTKLTFNSLLWESEGGLGWIHSIAFSNDGNKLIWSTHSSTICVATVSGSQQPP-SVK 181
S WG++L FN++ E G GW+H++ FS GN L ++ H S++ +A S +QPP ++
Sbjct: 187 SVWGSRLPFNTVCAEYPSG-GWVHAVGFSPSGNALAYAGHDSSVTIAYPSAPEQPPRALI 245
Query: 182 MILMDNLPFLTLVWAAPNTVIGAGHDCVPFTISTDKD------QLKLGTSLDS------- 322
+ + LP +L+WA + ++ AG++ P + ++ L GTS S
Sbjct: 246 TVKLSQLPLRSLLWANESAIVAAGYNYSPILLQGNESGWAHTRDLDAGTSKTSFTHTGNT 305
Query: 323 ---KEELNTNATLSAKDRFRQIDRIATADSNDSIINSKHKNAINEIRIMKGSNGSAQVLS 493
+EE + + + FR +D ++ S S + + H+N I +R G+ G+ +
Sbjct: 306 GEGREEEGPVSFTALRSTFRNMDLKGSSQSISS-LPTVHQNMIATLRPYAGTPGNITAFT 364
Query: 494 TIGRDGQLILWDL 532
+ G DG+++LW L
Sbjct: 365 SSGTDGRVVLWTL 377
>sp|P38328|ARPC1_YEAST Probable ARP2/3 complex 41 kDa subunit (p41-ARC)
Length = 384
Score = 67.0 bits (162), Expect = 6e-11
Identities = 46/196 (23%), Positives = 86/196 (43%), Gaps = 20/196 (10%)
Frame = +2
Query: 5 SNWGTKLTFNSLLWESEGGLGWIHSIAFSNDGNKLIWSTHSSTICVATVSGSQQPPSVKM 184
S WG K F L+ E G +IH + + + ++ + H T+ V Q P +
Sbjct: 196 SPWGQKFPFGCLIREWYQG-SYIHDVEWRSQMERIAYVAHDGTLNVV----DYQSPVQSV 250
Query: 185 ILMDNLPFLTLVWAAPNTVIGAGHDCVPFTISTDKDQLKLGTSLDSKEELNTNAT----- 349
+ LP+ +LVW + ++ G+ C P S + K +LD + ++A
Sbjct: 251 NAPEGLPYRSLVWINDHEIVCGGYSCHPVLFSEASEGWKFAKNLDKSDNNKSSALTASGN 310
Query: 350 ---------------LSAKDRFRQIDRIATADSNDSIINSKHKNAINEIRIMKGSNGSAQ 484
+SA +F+++D ++ + S H+NAI E+R SNG
Sbjct: 311 TDELSGNNDESSTFGISALRKFKELDLKGKVSTD--VQESAHENAIVELRPFAESNGQIT 368
Query: 485 VLSTIGRDGQLILWDL 532
+S+ G DG+++++ +
Sbjct: 369 QVSSCGLDGKIVIYTI 384
>sp|Q91VU6|WDR23_MOUSE WD-repeat protein 23
Length = 549
Score = 34.3 bits (77), Expect = 0.42
Identities = 39/190 (20%), Positives = 76/190 (40%), Gaps = 27/190 (14%)
Frame = +2
Query: 62 LGW-IHSIAFSNDGNKLIWSTHSSTICVATVSGSQQPPSVKMILMDNLPFLTLVWAAPN- 235
+GW + +AF+ DGN ++S+ S I + + G + + D F A +
Sbjct: 217 VGWSVLDVAFTPDGNHFLYSSWSDYIHICNIYGEGDTHTALDLRPDERRFAVFSIAVSSD 276
Query: 236 --TVIGAGHDCVPFTISTDKDQLKLGTSLDSKEELNTNATLSAKDRFRQIDRIATADSND 409
V+G +D + D++Q + ++S E+ ++ +A AD +
Sbjct: 277 GREVLGGANDGCLYVF--DREQNRRTLQIESHED--------------DVNAVAFADISS 320
Query: 410 SIINSKHKNAINEI---RIMK--------------------GSNGSAQVLSTIGRDGQLI 520
I+ S +AI ++ R M+ S G A+ L + +D +
Sbjct: 321 QILFSGGDDAICKVWDRRTMREDDPKPVGALAGHQDGITFIDSKGDARYLISNSKDQTIK 380
Query: 521 LWDLKTLSQK 550
LWD++ S +
Sbjct: 381 LWDIRRFSSR 390
>sp|Q8TEB1|WDR23_HUMAN WD-repeat protein 23
Length = 546
Score = 34.3 bits (77), Expect = 0.42
Identities = 39/190 (20%), Positives = 76/190 (40%), Gaps = 27/190 (14%)
Frame = +2
Query: 62 LGW-IHSIAFSNDGNKLIWSTHSSTICVATVSGSQQPPSVKMILMDNLPFLTLVWAAPN- 235
+GW + +AF+ DGN ++S+ S I + + G + + D F A +
Sbjct: 217 VGWSVLDVAFTPDGNHFLYSSWSDYIHICNIYGEGDTHTALDLRPDERRFAVFSIAVSSD 276
Query: 236 --TVIGAGHDCVPFTISTDKDQLKLGTSLDSKEELNTNATLSAKDRFRQIDRIATADSND 409
V+G +D + D++Q + ++S E+ ++ +A AD +
Sbjct: 277 GREVLGGANDGCLYVF--DREQNRRTLQIESHED--------------DVNAVAFADISS 320
Query: 410 SIINSKHKNAINEI---RIMK--------------------GSNGSAQVLSTIGRDGQLI 520
I+ S +AI ++ R M+ S G A+ L + +D +
Sbjct: 321 QILFSGGDDAICKVWDRRTMREDDPKPVGALAGHQDGITFIDSKGDARYLISNSKDQTIK 380
Query: 521 LWDLKTLSQK 550
LWD++ S +
Sbjct: 381 LWDIRRFSSR 390
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,790,095
Number of Sequences: 369166
Number of extensions: 1765278
Number of successful extensions: 4241
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4021
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4220
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7907893860
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)