Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_G18
(916 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P07602|SAP_HUMAN Proactivator polypeptide precursor [Con... 86 2e-16
sp|P26779|SAP_BOVIN Proactivator polypeptide precursor [Con... 81 4e-15
sp|O13035|SAP_CHICK Proactivator polypeptide precursor [Con... 68 4e-11
sp|Q61207|SAP_MOUSE Sulfated glycoprotein 1 precursor (SGP-... 64 5e-10
sp|P10960|SAP_RAT Sulfated glycoprotein 1 precursor (SGP-1)... 58 3e-08
sp|P50405|PSPB_MOUSE Pulmonary surfactant-associated protei... 38 0.045
sp|Q89330|POLG_ZYMVR Genome polyprotein [Contains: P1 prote... 37 0.077
sp|P20097|SAP_CAVPO Saposin C (CO-beta-glucosidase) (Glucos... 35 0.22
sp|P17129|PSPB_CANFA Pulmonary surfactant-associated protei... 34 0.65
sp|O36979|POLG_ZYMVS Genome polyprotein [Contains: P1 prote... 34 0.65
>sp|P07602|SAP_HUMAN Proactivator polypeptide precursor [Contains: Saposin A (Protein
A); Saposin B-Val; Saposin B (Sphingolipid activator
protein 1) (SAP-1) (Cerebroside sulfate activator)
(CSAct) (Dispersin) (Sulfatide/GM1 activator); Saposin C
(Co-beta-glucosidase) (A1 activator) (Glucosylceramidase
activator) (Sphingolipid activator protein 2) (SAP-2);
Saposin D (Protein C) (Component C)]
Length = 524
Score = 85.5 bits (210), Expect = 2e-16
Identities = 58/217 (26%), Positives = 101/217 (46%), Gaps = 5/217 (2%)
Frame = +2
Query: 146 CEICRFAILEVRTLLTDPGFQK-IFENFLINEICPHF-KTKQQQCTNDINQYYSLVVNII 319
CE+C F + EV L+ + +K I + F +++C K+ ++C ++ Y S +++I+
Sbjct: 315 CEVCEFLVKEVTKLIDNNKTEKEILDAF--DKMCSKLPKSLSEECQEVVDTYGSSILSIL 372
Query: 320 VEFLNPSL-CSELGLCNSTIKQVIMRQPLVQINRSKKTSNCRLCCKFYKYL-QTISSKSS 493
+E ++P L CS L LC+ T + V + + K C +C K YL + + S+
Sbjct: 373 LEEVSPELVCSMLHLCSGTRLPALT----VHVTQPKDGGFCEVCKKLVGYLDRNLEKNST 428
Query: 494 HSNLLFGLVSFCNQISAHERLECLKQFRNFNAVIAAFNKSKTINEF-CEMTKMCSHQRKN 670
+L L C+ + + +C + + V+ F C C K
Sbjct: 429 KQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHKP 488
Query: 671 PLGKNPCTWGPGFWCVSRKHAVACGPGAVKHCEMNVW 781
LG C WGP +WC + + A C AV+HC+ +VW
Sbjct: 489 LLGTEKCIWGPSYWCQNTETAAQC--NAVEHCKRHVW 523
Score = 42.4 bits (98), Expect = 0.002
Identities = 35/134 (26%), Positives = 65/134 (48%), Gaps = 5/134 (3%)
Frame = +2
Query: 2 DTYLPVIFSIARSTLNSKVICTELKLC--TLLSKKKISFLMNRSGNETLKCEICRFAILE 175
DTY I SI ++ +++C+ L LC T L + + G CE+C+ +
Sbjct: 362 DTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGG---FCEVCKKLVGY 418
Query: 176 V-RTLLTDPGFQKIFENFLINEICPHFKTK-QQQCTNDINQYYSLVVNIIVEFLNPS-LC 346
+ R L + Q+I + + C Q+QC + +Y +++ I+VE ++PS +C
Sbjct: 419 LDRNLEKNSTKQEILA--ALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVC 476
Query: 347 SELGLCNSTIKQVI 388
++G C S K ++
Sbjct: 477 LKIGACPSAHKPLL 490
Score = 37.7 bits (86), Expect = 0.045
Identities = 18/38 (47%), Positives = 20/38 (52%)
Frame = +2
Query: 674 LGKNPCTWGPGFWCVSRKHAVACGPGAVKHCEMNVWRQ 787
LG CT G WC + K A C GAVKHC VW +
Sbjct: 20 LGLKECTRGSAVWCQNVKTASDC--GAVKHCLQTVWNK 55
Score = 33.1 bits (74), Expect = 1.1
Identities = 53/285 (18%), Positives = 106/285 (37%), Gaps = 64/285 (22%)
Frame = +2
Query: 2 DTYLPVIFSIARSTLNSK-VICTELKLCTLLSKKKISFLMNRSGNETLK----------- 145
D+YLPVI I + ++ +C+ L LC L +K ++ L ++ E+ K
Sbjct: 111 DSYLPVILDIIKGEMSRPGEVCSALNLCESL-QKHLAELNHQKQLESNKIPELDMTEVVA 169
Query: 146 ----------------------------CEICRFAILEVRTLL-TDPGF-QKIFENFLIN 235
C+ C + +++T + T+ F Q + E+ +
Sbjct: 170 PFMANIPLLLYPQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEH--VK 227
Query: 236 EICPHFKTKQQQ-CTNDINQYYSLVVNIIVEFLNPSLCSELGLCNS-------------- 370
E C C N I+QY + + +++ +C+ +G C+
Sbjct: 228 EECDRLGPGMADICKNYISQYSEIAIQMMMHMQPKEICALVGFCDEVKEMPMQTLVPAKV 287
Query: 371 TIKQVIMRQPLVQ-INRSKKTSNCRLCCKFYKYL-----QTISSKSSHSNLLFGLVSFCN 532
K VI LV+ I + + + + C+ ++L + I + + +L C+
Sbjct: 288 ASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCS 347
Query: 533 QISAHERLECLKQFRNFNAVIAAFNKSKTINEF-CEMTKMCSHQR 664
++ EC + + + I + + E C M +CS R
Sbjct: 348 KLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTR 392
>sp|P26779|SAP_BOVIN Proactivator polypeptide precursor [Contains: Saposin A (Protein
A); Saposin B (Sphingolipid activator protein 1) (SAP-1)
(Cerebroside sulfate activator) (CSAct) (Dispersin)
(Sulfatide/GM1 activator); Saposin C
(Co-beta-glucosidase) (A1 activator) (Glucosylceramidase
activator) (Sphingolipid activator protein 2) (SAP-2);
Saposin D (Protein C) (Component C)]
Length = 525
Score = 81.3 bits (199), Expect = 4e-15
Identities = 56/216 (25%), Positives = 96/216 (44%), Gaps = 4/216 (1%)
Frame = +2
Query: 146 CEICRFAILEVRTLLTDPGFQKIFENFLINEICPHFKTK-QQQCTNDINQYYSLVVNIIV 322
CE+C F + EV L+ + ++ + L +++C T +QC ++ Y +++I++
Sbjct: 316 CEVCEFVVKEVAKLIDNNRTEEEILHAL-DKVCSKLPTSLAEQCQEVVDTYGRSILSILL 374
Query: 323 EFLNPSL-CSELGLCNSTIKQVIMRQPLVQINRSKKTSNCRLCCKFYKYL-QTISSKSSH 496
+ +P L CS L LC+S + V++ K C +C K YL + + S+
Sbjct: 375 DEASPELVCSMLHLCSSRG----LPAATVRVMPRKDGGFCEVCKKLVGYLDRNLEKNSTK 430
Query: 497 SNLLFGLVSFCNQISAHERLECLKQFRNFNAVIAAFNKSKTINEF-CEMTKMCSHQRKNP 673
+L L C+ + R +C + + V+ F C C K
Sbjct: 431 EQILAALEKGCSFLPDQYRKQCDQFVTEYEPVLIEILVEVMDPSFVCLKIGACPAAHKPL 490
Query: 674 LGKNPCTWGPGFWCVSRKHAVACGPGAVKHCEMNVW 781
LG C WGP +WC + + A C AV+HC +VW
Sbjct: 491 LGAEKCVWGPSYWCQNMESAALC--NAVEHCRRHVW 524
Score = 38.9 bits (89), Expect = 0.020
Identities = 31/134 (23%), Positives = 66/134 (49%), Gaps = 5/134 (3%)
Frame = +2
Query: 2 DTYLPVIFSIARSTLNSKVICTELKLCTL--LSKKKISFLMNRSGNETLKCEICRFAILE 175
DTY I SI + +++C+ L LC+ L + + + G CE+C+ +
Sbjct: 363 DTYGRSILSILLDEASPELVCSMLHLCSSRGLPAATVRVMPRKDGG---FCEVCKKLVGY 419
Query: 176 V-RTLLTDPGFQKIFENFLINEICPHFKTK-QQQCTNDINQYYSLVVNIIVEFLNPS-LC 346
+ R L + ++I + + C + ++QC + +Y +++ I+VE ++PS +C
Sbjct: 420 LDRNLEKNSTKEQILA--ALEKGCSFLPDQYRKQCDQFVTEYEPVLIEILVEVMDPSFVC 477
Query: 347 SELGLCNSTIKQVI 388
++G C + K ++
Sbjct: 478 LKIGACPAAHKPLL 491
Score = 36.6 bits (83), Expect = 0.10
Identities = 17/36 (47%), Positives = 19/36 (52%)
Frame = +2
Query: 674 LGKNPCTWGPGFWCVSRKHAVACGPGAVKHCEMNVW 781
LG CT G WC + K A C GAV+HC VW
Sbjct: 20 LGLRECTRGSAVWCQNVKTAADC--GAVQHCLQTVW 53
>sp|O13035|SAP_CHICK Proactivator polypeptide precursor [Contains: Saposin A; Saposin B;
Saposin C; Saposin D]
Length = 518
Score = 67.8 bits (164), Expect = 4e-11
Identities = 52/219 (23%), Positives = 95/219 (43%), Gaps = 7/219 (3%)
Frame = +2
Query: 146 CEICRFAILEVRTLLTDPGFQK--IFENFLINEICPHFKTKQQQCTNDINQYYSLVVNII 319
CEIC + EV LL ++ + E ++ + P + + QC + I Y +++++
Sbjct: 311 CEICETMVKEVTGLLESNKTEEEIVHEMEVVCYLLP--ASVKDQCKDFIEVYGQALIDML 368
Query: 320 VEFLNP-SLCSELGLC--NSTIKQVIMRQPLVQINRSKKTSNCRLCCKFYKYLQTISSKS 490
+E NP ++C L C N +Q ++ +P C +C Y K+
Sbjct: 369 LEATNPEAVCVMLKCCAANKPPQQPVVVKPAGGF--------CDICKMIVAYADKELEKN 420
Query: 491 SHSNLLFGLVS-FCNQISAHERLECLKQFRNFNAVIAAFNKSKTINEF-CEMTKMCSHQR 664
+ + + L+ C+ + +C++ + V+ F C +C +
Sbjct: 421 ATTTEIEALLEKVCHFLPESVSDQCVQFVEQYEPVVVQLLAEMMDPTFVCTKLGVCGAAK 480
Query: 665 KNPLGKNPCTWGPGFWCVSRKHAVACGPGAVKHCEMNVW 781
K LG++ C WGPG+WC + + A C AV HC +VW
Sbjct: 481 KPLLGEDACVWGPGYWCKNMETAAQC--NAVDHCRRHVW 517
Score = 40.8 bits (94), Expect = 0.005
Identities = 18/36 (50%), Positives = 21/36 (58%)
Frame = +2
Query: 674 LGKNPCTWGPGFWCVSRKHAVACGPGAVKHCEMNVW 781
L + C GP WC S + A CG AVKHC+ NVW
Sbjct: 21 LWQKDCAKGPEVWCQSLRTASQCG--AVKHCQQNVW 54
>sp|Q61207|SAP_MOUSE Sulfated glycoprotein 1 precursor (SGP-1) (Prosaposin)
Length = 557
Score = 64.3 bits (155), Expect = 5e-10
Identities = 49/247 (19%), Positives = 94/247 (38%), Gaps = 30/247 (12%)
Frame = +2
Query: 131 NETLKCEICRFAILEVRTLLTDPGFQKIFENFLINEICPHFKTKQQQCTNDINQYYSLVV 310
+ + C+ C+F + + L+ + +++ L N + +C + + ++
Sbjct: 312 HNVILCQTCQFVMNKFSELIVNNATEELLVKGLSNACALLPDPARTKCQEVVGTFGPSLL 371
Query: 311 NIIVEFLNPS-LCSELGLCNS-------------TIKQVIMRQPL--------------V 406
+I + +NPS LC +GLC + I ++++P
Sbjct: 372 DIFIHEVNPSSLCGVIGLCAARPELVEALEQPAPAIVSALLKEPTPPKQPAQPKQSALPA 431
Query: 407 QINRSKKTSNCRLCCKFYKYLQ-TISSKSSHSNLLFGLVSFCNQISAHERLECLKQFRNF 583
+ K C +C K YL+ + S+ +L L C+ + + +C +
Sbjct: 432 HVPPQKNGGFCEVCKKLVLYLEHNLEKNSTKEEILAALEKGCSFLPDPYQKQCDDFVAEY 491
Query: 584 NAVIAAFNKSKTINEF-CEMTKMCSHQRKNPLGKNPCTWGPGFWCVSRKHAVACGPGAVK 760
++ F C +C K LG C WGP +WC + + A C AV
Sbjct: 492 EPLLLEILVEVMDPGFVCSKIGVCPSAYKLLLGTEKCVWGPSYWCQNMETAARC--NAVD 549
Query: 761 HCEMNVW 781
HC+ +VW
Sbjct: 550 HCKRHVW 556
Score = 40.4 bits (93), Expect = 0.007
Identities = 32/131 (24%), Positives = 62/131 (47%), Gaps = 6/131 (4%)
Frame = +2
Query: 50 SKVICTELKLCTLLSKKKI--SFLMNRSGNETLKCEICRFAILEVRTLLTDPGFQKIFEN 223
S V+C ++K K + ++ ++L C+IC+ + E LL D Q+ +
Sbjct: 29 SAVLCRDVKTAVDCGAVKHCQQMVWSKPTAKSLPCDICKTVVTEAGNLLKDNATQEEILH 88
Query: 224 FLINEICP--HFKTKQQQCTNDINQYYSLVVNIIV-EFLNP-SLCSELGLCNSTIKQVIM 391
+L + C H + C ++ Y +++++I E NP +CS L LC S +++ +
Sbjct: 89 YL-EKTCEWIHDSSLSASCKEVVDSYLPVILDMIKGEMSNPGEVCSALNLCQS-LQEYLA 146
Query: 392 RQPLVQINRSK 424
Q Q+ +K
Sbjct: 147 EQNQKQLESNK 157
Score = 31.2 bits (69), Expect = 4.2
Identities = 15/31 (48%), Positives = 17/31 (54%)
Frame = +2
Query: 689 CTWGPGFWCVSRKHAVACGPGAVKHCEMNVW 781
C+ G C K AV CG AVKHC+ VW
Sbjct: 25 CSGGSAVLCRDVKTAVDCG--AVKHCQQMVW 53
>sp|P10960|SAP_RAT Sulfated glycoprotein 1 precursor (SGP-1) (Prosaposin)
Length = 554
Score = 58.2 bits (139), Expect = 3e-08
Identities = 47/242 (19%), Positives = 93/242 (38%), Gaps = 30/242 (12%)
Frame = +2
Query: 146 CEICRFAILEVRTLLTDPGFQKIFENFLINEICPHFKTKQQQCTNDINQYYSLVVNIIVE 325
C++C+ + ++ L+ + +++ L +C + + ++++++
Sbjct: 314 CQVCQLVMRKLSELIINNATEELLIKGLSKACSLLPAPASTKCQEVLVTFGPSLLDVLMH 373
Query: 326 FLNPS-LCSELGLCNSTIKQV-IMRQPLVQINRS-------------------------- 421
+NP+ LC + LC++ V + QP I +
Sbjct: 374 EVNPNFLCGVISLCSANPNLVGTLEQPAAAIVSALPKEPAPPKQPEEPKQSALRAHVPPQ 433
Query: 422 KKTSNCRLCCKFYKYLQ-TISSKSSHSNLLFGLVSFCNQISAHERLECLKQFRNFNAVIA 598
K C +C K YL+ + S+ +L L C+ + + +C + + ++
Sbjct: 434 KNGGFCEVCKKLVIYLEHNLEKNSTKEEILAALEKGCSFLPDPYQKQCDEFVAEYEPLLL 493
Query: 599 AFNKSKTINEF-CEMTKMCSHQRKNPLGKNPCTWGPGFWCVSRKHAVACGPGAVKHCEMN 775
F C +C K LG C WGPG+WC + + A C AV HC+ +
Sbjct: 494 EILVEVMDPSFVCSKIGVCPSAYKLLLGTEKCVWGPGYWCQNSETAARC--NAVDHCKRH 551
Query: 776 VW 781
VW
Sbjct: 552 VW 553
Score = 38.9 bits (89), Expect = 0.020
Identities = 31/131 (23%), Positives = 62/131 (47%), Gaps = 6/131 (4%)
Frame = +2
Query: 50 SKVICTELKLCTLLSKKKI--SFLMNRSGNETLKCEICRFAILEVRTLLTDPGFQKIFEN 223
S V+C ++K K + ++ ++L C+IC+ + E LL D ++ +
Sbjct: 29 SAVVCRDVKTAVDCRAVKHCQQMVWSKPTAKSLPCDICKTVVTEAGNLLKDNATEEEILH 88
Query: 224 FLINEICP--HFKTKQQQCTNDINQYYSLVVNIIV-EFLNP-SLCSELGLCNSTIKQVIM 391
+L + C H + C ++ Y +++++I E NP +CS L LC S +++ +
Sbjct: 89 YL-EKTCAWIHDSSLSASCKEVVDSYLPVILDMIKGEMSNPGEVCSALNLCQS-LQEYLA 146
Query: 392 RQPLVQINRSK 424
Q Q+ +K
Sbjct: 147 EQNQRQLESNK 157
Score = 32.0 bits (71), Expect = 2.5
Identities = 54/282 (19%), Positives = 107/282 (37%), Gaps = 64/282 (22%)
Frame = +2
Query: 2 DTYLPVIFSIARSTL-NSKVICTELKLCTLLSK------------KKIS----------F 112
D+YLPVI + + + N +C+ L LC L + KI F
Sbjct: 111 DSYLPVILDMIKGEMSNPGEVCSALNLCQSLQEYLAEQNQRQLESNKIPEVDLARVVAPF 170
Query: 113 LMN----------------RSGNETLKCEICRFAILEVRTLL-TDPGF-QKIFENFLINE 238
+ N NE + C+ C + +++T + T+ F Q + ++ + E
Sbjct: 171 MSNIPLLLYPQDRPRSQPQPKANEDV-CQDCMKLVTDIQTAVRTNSSFVQGLVDH--VKE 227
Query: 239 ICPHFKTKQQQ-CTNDINQYYSLVVNIIVEFLNPSLCSELGLCNSTIKQVIMRQ------ 397
C C N ++QY + V +++ +C +G C+ +K+V MR
Sbjct: 228 DCDRLGPGVSDICKNYVDQYSEVAVQMMMHMQPKEICVMVGFCDE-VKRVPMRTLVPATE 286
Query: 398 ------PLVQIN--------RSKKTSNCRLC-CKFYKYLQTISSKSSHSNLLFGLVSFCN 532
P +++ +++ C++C K + I + ++ L+ GL C+
Sbjct: 287 AIKNILPALELTDPYEQDVIQAQNVIFCQVCQLVMRKLSELIINNATEELLIKGLSKACS 346
Query: 533 QISAHERLECLKQFRNFN-AVIAAFNKSKTINEFCEMTKMCS 655
+ A +C + F +++ N C + +CS
Sbjct: 347 LLPAPASTKCQEVLVTFGPSLLDVLMHEVNPNFLCGVISLCS 388
>sp|P50405|PSPB_MOUSE Pulmonary surfactant-associated protein B precursor (SP-B)
(Pulmonary surfactant-associated proteolipid SPL(Phe))
Length = 377
Score = 37.7 bits (86), Expect = 0.045
Identities = 16/31 (51%), Positives = 18/31 (58%)
Frame = +2
Query: 689 CTWGPGFWCVSRKHAVACGPGAVKHCEMNVW 781
C GP FWC S +HAV C A+ HC VW
Sbjct: 31 CAQGPQFWCQSLEHAVQC--RALGHCLQEVW 59
Score = 30.0 bits (66), Expect = 9.4
Identities = 11/27 (40%), Positives = 16/27 (59%)
Frame = +2
Query: 2 DTYLPVIFSIARSTLNSKVICTELKLC 82
D YLP++ +S +N K IC + LC
Sbjct: 116 DVYLPLVIDYFQSQINPKAICNHVGLC 142
>sp|Q89330|POLG_ZYMVR Genome polyprotein [Contains: P1 proteinase (N-terminal protein);
Helper component proteinase (HC-pro); Protein P3; 6 kDa
protein 1 (6K1); Cytoplasmic inclusion protein (CI); 6
kDa protein 2 (6K2); Viral genome-linked protein (VPg);
Nuclear inclusion protein A (NI-a) (NIa) (NIa-pro) (49
kDa proteinase) (49 kDa-Pro); Nuclear inclusion protein B
(NI-b) (NIb) (RNA-directed RNA polymerase); Coat protein
(CP)]
Length = 3083
Score = 37.0 bits (84), Expect = 0.077
Identities = 20/48 (41%), Positives = 26/48 (54%), Gaps = 2/48 (4%)
Frame = -1
Query: 226 KIFKNFLKSRISQQCSDFKNSKSAYFTLQCFITTSIHKK--RDFLFRK 89
K F F + +++QQ D K S F +CFITT +H K RD RK
Sbjct: 948 KRFSIFTERKLTQQAKDGKRVSSLQFVHECFITTRVHAKSIRDVGMRK 995
>sp|P20097|SAP_CAVPO Saposin C (CO-beta-glucosidase) (Glucosylceramidase activator)
(Sphingolipid activator protein 2) (SAP-2)
Length = 81
Score = 35.4 bits (80), Expect = 0.22
Identities = 19/80 (23%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Frame = +2
Query: 134 ETLKCEICRFAILEVRTLLTDPGFQKIFENFLINEICPHFKTKQQQCTNDINQYYSLVVN 313
E++ C+ C + + +V L+ + ++ + L + ++ + C ++ Y +V
Sbjct: 1 ESVTCKACEYVVKKVMELIDNNRTEEKIIHALDSVCALLPESVSEVCQEVVDTYGDSIVA 60
Query: 314 IIVEFLNPSL-CSELGLCNS 370
++++ ++P L CSELGLC S
Sbjct: 61 LLLQEMSPELVCSELGLCMS 80
>sp|P17129|PSPB_CANFA Pulmonary surfactant-associated protein B precursor (SP-B) (6 kDa
protein) (Pulmonary surfactant-associated proteolipid
SPL(Phe)) (Pulmonary surfactant protein 18) (SP 18)
Length = 363
Score = 33.9 bits (76), Expect = 0.65
Identities = 14/31 (45%), Positives = 17/31 (54%)
Frame = +2
Query: 689 CTWGPGFWCVSRKHAVACGPGAVKHCEMNVW 781
C GP FWC S + A+ C A+ HC VW
Sbjct: 25 CARGPAFWCQSLEQALQC--RALGHCLQEVW 53
Score = 33.9 bits (76), Expect = 0.65
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Frame = +2
Query: 146 CEICRFAILEVRTLLTDPGFQKIFENFLINE--ICPHFKTKQQQCTNDINQYYSLVVNII 319
C+ C+ + + + + FQ + FL +E + P K QC + + Y+ +VV+
Sbjct: 62 CQECQDIVRILTKMTKEAIFQDMVRKFLEHECDVLP-LKLLTPQCHHMLGTYFPVVVDYF 120
Query: 320 VEFLNPS-LCSELGLC 364
+NP +C LGLC
Sbjct: 121 QSQINPKIICKHLGLC 136
Score = 30.8 bits (68), Expect = 5.5
Identities = 12/26 (46%), Positives = 16/26 (61%)
Frame = +2
Query: 5 TYLPVIFSIARSTLNSKVICTELKLC 82
TY PV+ +S +N K+IC L LC
Sbjct: 111 TYFPVVVDYFQSQINPKIICKHLGLC 136
>sp|O36979|POLG_ZYMVS Genome polyprotein [Contains: P1 proteinase (N-terminal protein);
Helper component proteinase (HC-pro); Protein P3; 6 kDa
protein 1 (6K1); Cytoplasmic inclusion protein (CI); 6
kDa protein 2 (6K2); Viral genome-linked protein (VPg);
Nuclear inclusion protein A (NI-a) (NIa) (NIa-pro) (49
kDa proteinase) (49 kDa-Pro); Nuclear inclusion protein B
(NI-b) (NIb) (RNA-directed RNA polymerase); Coat protein
(CP)]
Length = 3083
Score = 33.9 bits (76), Expect = 0.65
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 2/48 (4%)
Frame = -1
Query: 226 KIFKNFLKSRISQQCSDFKNSKSAYFTLQCFITTSIHKK--RDFLFRK 89
K F F + ++Q+ + K++ S F +CFITT +H K RD RK
Sbjct: 948 KQFSIFTERNLTQRAKERKHASSLQFVHECFITTRVHAKSIRDAGVRK 995
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 103,863,184
Number of Sequences: 369166
Number of extensions: 2128155
Number of successful extensions: 5667
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5403
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5655
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9318621220
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)