Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_G05-2
(431 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O19049|HNRPK_RABIT Heterogeneous nuclear ribonucleoprote... 60 3e-09
sp|P61980|HNRPK_RAT Heterogeneous nuclear ribonucleoprotein... 59 6e-09
sp|P60335|PCBP1_MOUSE Poly(rC)-binding protein 1 (Alpha-CP1... 44 1e-04
sp|Q15366|PCBP2_HUMAN Poly(rC)-binding protein 2 (Alpha-CP2... 44 2e-04
sp|Q61990|PCBP2_MOUSE Poly(rC)-binding protein 2 (Alpha-CP2... 44 2e-04
sp|P57722|PCBP3_MOUSE Poly(rC)-binding protein 3 (Alpha-CP3) 42 6e-04
sp|P57721|PCBP3_HUMAN Poly(rC)-binding protein 3 (Alpha-CP3) 42 6e-04
sp|Q96AE4|FUBP1_HUMAN Far upstream element-binding protein ... 42 6e-04
sp|Q91WJ8|FUBP1_MOUSE Far upstream element-binding protein ... 41 0.001
sp|P57723|PCBP4_HUMAN Poly(rC)-binding protein 4 (Alpha-CP4) 39 0.005
>sp|O19049|HNRPK_RABIT Heterogeneous nuclear ribonucleoprotein K (hnRNP K)
Length = 463
Score = 59.7 bits (143), Expect = 3e-09
Identities = 34/112 (30%), Positives = 59/112 (52%), Gaps = 13/112 (11%)
Frame = +2
Query: 131 IEFRFLIPSKAASIIIGKGGERIQRLRHECNARLSIPDNHGPERVFILESTMDNCIKVWH 310
+E R L+ SK A +IGKGG+ I+ LR + NA +S+PD+ GPER+ + + ++ ++
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILK 102
Query: 311 DCLPDLKDCM---FPNVDQRKSSGS----------FRDDNPDMDLRFLVHDS 427
+P L++ + P + S F+ + D +LR L+H S
Sbjct: 103 KIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHFKGSDFDCELRLLIHQS 154
Score = 40.0 bits (92), Expect = 0.002
Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
Frame = +2
Query: 122 GNRIEFRFLIPSKAASIIIGKGGERIQRLRHECNARLSI--PDNHGPERVFILESTMD 289
G I + IP A IIGKGG+RI+++RHE A + I P +R+ + T D
Sbjct: 385 GPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQD 442
>sp|P61980|HNRPK_RAT Heterogeneous nuclear ribonucleoprotein K (dC stretch-binding
protein) (CSBP)
sp|P61979|HNRPK_MOUSE Heterogeneous nuclear ribonucleoprotein K
sp|P61978|HNRPK_HUMAN Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation
up-regulated nuclear protein) (TUNP)
Length = 463
Score = 58.5 bits (140), Expect = 6e-09
Identities = 33/112 (29%), Positives = 59/112 (52%), Gaps = 13/112 (11%)
Frame = +2
Query: 131 IEFRFLIPSKAASIIIGKGGERIQRLRHECNARLSIPDNHGPERVFILESTMDNCIKVWH 310
+E R L+ SK A +IGKGG+ I+ LR + NA +S+PD+ GPER+ + + ++ ++
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILK 102
Query: 311 DCLPDLKDCM---FPNVDQRKSSGS----------FRDDNPDMDLRFLVHDS 427
+P L++ + P + S ++ + D +LR L+H S
Sbjct: 103 KIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQS 154
Score = 40.0 bits (92), Expect = 0.002
Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
Frame = +2
Query: 122 GNRIEFRFLIPSKAASIIIGKGGERIQRLRHECNARLSI--PDNHGPERVFILESTMD 289
G I + IP A IIGKGG+RI+++RHE A + I P +R+ + T D
Sbjct: 385 GPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQD 442
>sp|P60335|PCBP1_MOUSE Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1)
sp|Q15365|PCBP1_HUMAN Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1) (Nucleic
acid-binding protein SUB2.3)
sp|O19048|PCBP1_RABIT Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1)
Length = 356
Score = 44.3 bits (103), Expect = 1e-04
Identities = 29/100 (29%), Positives = 50/100 (50%)
Frame = +2
Query: 131 IEFRFLIPSKAASIIIGKGGERIQRLRHECNARLSIPDNHGPERVFILESTMDNCIKVWH 310
+ R L+ K IIGK GE ++R+R E AR++I + + PER+ L + K +
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIITLTGPTNAIFKAFA 73
Query: 311 DCLPDLKDCMFPNVDQRKSSGSFRDDNPDMDLRFLVHDSQ 430
+ L++ + N S+ + R P + LR +V +Q
Sbjct: 74 MIIDKLEEDI--NSSMTNSTAASR---PPVTLRLVVPATQ 108
Score = 28.5 bits (62), Expect = 6.3
Identities = 10/36 (27%), Positives = 21/36 (58%)
Frame = +2
Query: 131 IEFRFLIPSKAASIIIGKGGERIQRLRHECNARLSI 238
+ R ++P+ +IGKGG +I+ +R A++ +
Sbjct: 98 VTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQV 133
>sp|Q15366|PCBP2_HUMAN Poly(rC)-binding protein 2 (Alpha-CP2) (hnRNP-E2)
Length = 365
Score = 43.5 bits (101), Expect = 2e-04
Identities = 27/100 (27%), Positives = 49/100 (49%)
Frame = +2
Query: 131 IEFRFLIPSKAASIIIGKGGERIQRLRHECNARLSIPDNHGPERVFILESTMDNCIKVWH 310
+ R L+ K IIGK GE ++++R E AR++I + + PER+ L + K +
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFA 73
Query: 311 DCLPDLKDCMFPNVDQRKSSGSFRDDNPDMDLRFLVHDSQ 430
+ L++ + ++ + S P + LR +V SQ
Sbjct: 74 MIIDKLEEDISSSM-----TNSTAASRPPVTLRLVVPASQ 108
Score = 29.3 bits (64), Expect = 3.7
Identities = 18/84 (21%), Positives = 36/84 (42%), Gaps = 3/84 (3%)
Frame = +2
Query: 131 IEFRFLIPSKAASIIIGKGGERIQRLRHECNARLSIPDNHGP---ERVFILESTMDNCIK 301
+ R ++P+ +IGKGG +I+ +R A++ + + P ER + + I
Sbjct: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSII- 156
Query: 302 VWHDCLPDLKDCMFPNVDQRKSSG 373
+C+ + M + Q G
Sbjct: 157 ---ECVKQICVVMLETLSQSPPKG 177
>sp|Q61990|PCBP2_MOUSE Poly(rC)-binding protein 2 (Alpha-CP2) (Putative heterogeneous
nuclear ribonucleoprotein X) (hnRNP X) (CTBP) (CBP)
Length = 362
Score = 43.5 bits (101), Expect = 2e-04
Identities = 27/100 (27%), Positives = 49/100 (49%)
Frame = +2
Query: 131 IEFRFLIPSKAASIIIGKGGERIQRLRHECNARLSIPDNHGPERVFILESTMDNCIKVWH 310
+ R L+ K IIGK GE ++++R E AR++I + + PER+ L + K +
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFA 73
Query: 311 DCLPDLKDCMFPNVDQRKSSGSFRDDNPDMDLRFLVHDSQ 430
+ L++ + ++ + S P + LR +V SQ
Sbjct: 74 MIIDKLEEDISSSM-----TNSTAASRPPVTLRLVVPASQ 108
Score = 28.9 bits (63), Expect = 4.8
Identities = 10/36 (27%), Positives = 21/36 (58%)
Frame = +2
Query: 131 IEFRFLIPSKAASIIIGKGGERIQRLRHECNARLSI 238
+ R ++P+ +IGKGG +I+ +R A++ +
Sbjct: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQV 133
>sp|P57722|PCBP3_MOUSE Poly(rC)-binding protein 3 (Alpha-CP3)
Length = 339
Score = 42.0 bits (97), Expect = 6e-04
Identities = 27/100 (27%), Positives = 47/100 (47%)
Frame = +2
Query: 131 IEFRFLIPSKAASIIIGKGGERIQRLRHECNARLSIPDNHGPERVFILESTMDNCIKVWH 310
+ R L+ K IIGK GE ++++R E AR++I + + PER+ + D K +
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFA 73
Query: 311 DCLPDLKDCMFPNVDQRKSSGSFRDDNPDMDLRFLVHDSQ 430
++ + ++ S S P + LR +V SQ
Sbjct: 74 MIAYKFEEDIINSM-----SNSPATSKPPVTLRLVVPASQ 108
Score = 33.5 bits (75), Expect = 0.20
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 6/63 (9%)
Frame = +2
Query: 131 IEFRFLIPSKAASIIIGKGGERIQRLRHECNARLSIPDNHGP---ERVFILESTMD---N 292
+ R ++P+ +IGKGG +I+ +R A++ + + P ER + T D
Sbjct: 98 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQ 157
Query: 293 CIK 301
C+K
Sbjct: 158 CVK 160
>sp|P57721|PCBP3_HUMAN Poly(rC)-binding protein 3 (Alpha-CP3)
Length = 339
Score = 42.0 bits (97), Expect = 6e-04
Identities = 27/100 (27%), Positives = 47/100 (47%)
Frame = +2
Query: 131 IEFRFLIPSKAASIIIGKGGERIQRLRHECNARLSIPDNHGPERVFILESTMDNCIKVWH 310
+ R L+ K IIGK GE ++++R E AR++I + + PER+ + D K +
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFA 73
Query: 311 DCLPDLKDCMFPNVDQRKSSGSFRDDNPDMDLRFLVHDSQ 430
++ + ++ S S P + LR +V SQ
Sbjct: 74 MIAYKFEEDIINSM-----SNSPATSKPPVTLRLVVPASQ 108
Score = 33.5 bits (75), Expect = 0.20
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 6/63 (9%)
Frame = +2
Query: 131 IEFRFLIPSKAASIIIGKGGERIQRLRHECNARLSIPDNHGP---ERVFILESTMD---N 292
+ R ++P+ +IGKGG +I+ +R A++ + + P ER + T D
Sbjct: 98 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQ 157
Query: 293 CIK 301
C+K
Sbjct: 158 CVK 160
>sp|Q96AE4|FUBP1_HUMAN Far upstream element-binding protein 1 (FUSE-binding protein 1)
(FBP) (DNA helicase V) (HDH V)
Length = 643
Score = 42.0 bits (97), Expect = 6e-04
Identities = 18/46 (39%), Positives = 27/46 (58%)
Frame = +2
Query: 119 PGNRIEFRFLIPSKAASIIIGKGGERIQRLRHECNARLSIPDNHGP 256
PG EF F++P+ +IIGKGGE I+ + + AR+ + N P
Sbjct: 372 PGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPP 417
Score = 36.6 bits (83), Expect = 0.023
Identities = 19/52 (36%), Positives = 31/52 (59%), Gaps = 2/52 (3%)
Frame = +2
Query: 143 FLIPSKAASIIIGKGGERIQRLRHECNARLSI-PDNHG-PERVFILESTMDN 292
+ +P IIG+GGE+I R++ E ++ I PD+ G PER +L T ++
Sbjct: 104 YKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPES 155
Score = 36.6 bits (83), Expect = 0.023
Identities = 17/52 (32%), Positives = 31/52 (59%), Gaps = 4/52 (7%)
Frame = +2
Query: 119 PGNRIEFRFLIPSKAASIIIGKGGERIQRLRHECNARLSI----PDNHGPER 262
PGN ++ +IP+ A ++IGKGGE I++L+ ++ + P N G ++
Sbjct: 182 PGNAVQ-EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADK 232
>sp|Q91WJ8|FUBP1_MOUSE Far upstream element-binding protein 1 (FUSE-binding protein 1)
(FBP)
Length = 651
Score = 41.2 bits (95), Expect = 0.001
Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 5/60 (8%)
Frame = +2
Query: 119 PGNRIEFRFLIPSKAASIIIGKGGERIQRLRHECNARLSI----PDNHGPE-RVFILEST 283
PG EF F++P+ +IIGKGGE I+ + + AR+ + P N P ++F + T
Sbjct: 369 PGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRSPPPNADPNMKLFTIRGT 428
Score = 36.6 bits (83), Expect = 0.023
Identities = 19/52 (36%), Positives = 31/52 (59%), Gaps = 2/52 (3%)
Frame = +2
Query: 143 FLIPSKAASIIIGKGGERIQRLRHECNARLSI-PDNHG-PERVFILESTMDN 292
+ +P IIG+GGE+I R++ E ++ I PD+ G PER +L T ++
Sbjct: 101 YKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPES 152
Score = 36.6 bits (83), Expect = 0.023
Identities = 17/52 (32%), Positives = 31/52 (59%), Gaps = 4/52 (7%)
Frame = +2
Query: 119 PGNRIEFRFLIPSKAASIIIGKGGERIQRLRHECNARLSI----PDNHGPER 262
PGN ++ +IP+ A ++IGKGGE I++L+ ++ + P N G ++
Sbjct: 179 PGNAVQ-EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADK 229
>sp|P57723|PCBP4_HUMAN Poly(rC)-binding protein 4 (Alpha-CP4)
Length = 403
Score = 38.9 bits (89), Expect = 0.005
Identities = 17/45 (37%), Positives = 28/45 (62%)
Frame = +2
Query: 131 IEFRFLIPSKAASIIIGKGGERIQRLRHECNARLSIPDNHGPERV 265
+ R L+ K IIGK GE ++R+R + +AR++I + PER+
Sbjct: 18 LTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERI 62
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,306,462
Number of Sequences: 369166
Number of extensions: 914036
Number of successful extensions: 2300
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2187
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2299
length of database: 68,354,980
effective HSP length: 100
effective length of database: 49,881,480
effective search space used: 2144903640
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)