Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_018_F12 (806 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P54253|ATX1_HUMAN Ataxin-1 (Spinocerebellar ataxia type ... 73 1e-12 sp|Q63540|ATX1_RAT Ataxin-1 (Spinocerebellar ataxia type 1 ... 73 1e-12 sp|P54254|ATX1_MOUSE Ataxin-1 (Spinocerebellar ataxia type ... 73 1e-12 sp|Q5DRB8|PCDG2_PANTR Protocadherin gamma A2 precursor (PCD... 31 4.6 sp|Q9Y5H1|PCDG2_HUMAN Protocadherin gamma A2 precursor (PCD... 30 5.9 sp|P44708|GLMS_HAEIN Glucosamine--fructose-6-phosphate amin... 30 5.9 sp|Q971D7|SYFA_SULTO Phenylalanyl-tRNA synthetase alpha cha... 30 7.8
>sp|P54253|ATX1_HUMAN Ataxin-1 (Spinocerebellar ataxia type 1 protein) Length = 816 Score = 72.8 bits (177), Expect = 1e-12 Identities = 48/139 (34%), Positives = 72/139 (51%), Gaps = 12/139 (8%) Frame = +2 Query: 140 FQKGRLIKMSDGELKVIESLSASDFEKSCKSHDGMALVSSEVKLIEVSHSDNTARIQL-- 313 F KG +I++++GELK +E L DF +S + + + + SS V+ IE SHS A IQ Sbjct: 575 FMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIEDSHSPGVAVIQFAV 634 Query: 314 -NHDGRSSVIVVPVAKPFFTRDSGWAAIDPEACLNKYNLHATKLQLNNICFCL------- 469 H + SV V+ V PFF GW++ PE ++L +KL + ++C L Sbjct: 635 GEHRAQVSVEVL-VEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKN 693 Query: 470 --VKKKLPFDEQNSLINSS 520 VKK P D + L+ S Sbjct: 694 GSVKKGQPVDPASVLLKHS 712
>sp|Q63540|ATX1_RAT Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog) Length = 789 Score = 72.8 bits (177), Expect = 1e-12 Identities = 47/136 (34%), Positives = 72/136 (52%), Gaps = 12/136 (8%) Frame = +2 Query: 140 FQKGRLIKMSDGELKVIESLSASDFEKSCKSHDGMALVSSEVKLIEVSHSDNTARIQL-- 313 F KG +I++++GELK +E L DF +S + + + + SS V+ IE SHS A IQ Sbjct: 548 FMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIEDSHSPGVAVIQFAV 607 Query: 314 -NHDGRSSVIVVPVAKPFFTRDSGWAAIDPEACLNKYNLHATKLQLNNICFCL------- 469 H + SV V+ V PFF GW++ PE ++L +KL + ++C L Sbjct: 608 GEHRAQVSVEVL-VEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKN 666 Query: 470 --VKKKLPFDEQNSLI 511 VKK P D ++L+ Sbjct: 667 GSVKKGQPVDPASALL 682
>sp|P54254|ATX1_MOUSE Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog) Length = 792 Score = 72.8 bits (177), Expect = 1e-12 Identities = 43/118 (36%), Positives = 65/118 (55%), Gaps = 3/118 (2%) Frame = +2 Query: 140 FQKGRLIKMSDGELKVIESLSASDFEKSCKSHDGMALVSSEVKLIEVSHSDNTARIQL-- 313 F KG +I++++GELK +E L DF +S + + + + SS V+ IE SHS A IQ Sbjct: 550 FMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIHSSTVERIEESHSPGVAVIQFAV 609 Query: 314 -NHDGRSSVIVVPVAKPFFTRDSGWAAIDPEACLNKYNLHATKLQLNNICFCLVKKKL 484 H + SV V+ V PFF GW++ PE ++L +KL + ++C L K L Sbjct: 610 GEHRAQVSVEVL-VEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNL 666
>sp|Q5DRB8|PCDG2_PANTR Protocadherin gamma A2 precursor (PCDH-gamma-A2) Length = 932 Score = 30.8 bits (68), Expect = 4.6 Identities = 35/157 (22%), Positives = 63/157 (40%), Gaps = 3/157 (1%) Frame = +2 Query: 53 TLQNTNFTPRHMASVIRKLSENSNDIQEPFQKGRLIKMSDGELKVIESLSASD---FEKS 223 T+ T+ + A V+ L ++ + E F+ +K + GEL +I+ L D E Sbjct: 263 TVTATDADEGYYAQVVYFLEKSPGETSEVFE----LKSTSGELTIIKDLDYEDATFHEID 318 Query: 224 CKSHDGMALVSSEVKLIEVSHSDNTARIQLNHDGRSSVIVVPVAKPFFTRDSGWAAIDPE 403 ++ DG L++ ++ V ++ A SSV + DS P Sbjct: 319 IEAQDGPGLLTRAKVIVTVLDVNDNAPEFYMTSATSSV----------SEDSL-----PG 363 Query: 404 ACLNKYNLHATKLQLNNICFCLVKKKLPFDEQNSLIN 514 + +N+H N C + + LPF + S+ N Sbjct: 364 TIIGLFNVHDRDSGQNAFTTCSLPENLPFKLEKSVDN 400
>sp|Q9Y5H1|PCDG2_HUMAN Protocadherin gamma A2 precursor (PCDH-gamma-A2) Length = 932 Score = 30.4 bits (67), Expect = 5.9 Identities = 35/157 (22%), Positives = 63/157 (40%), Gaps = 3/157 (1%) Frame = +2 Query: 53 TLQNTNFTPRHMASVIRKLSENSNDIQEPFQKGRLIKMSDGELKVIESLSASD---FEKS 223 T+ T+ + A V+ L ++ + E F+ +K + GEL +I+ L D E Sbjct: 263 TVTATDADEGYYAQVVYFLEKSPGETSEVFE----LKSTSGELTIIKDLDYEDATFHEID 318 Query: 224 CKSHDGMALVSSEVKLIEVSHSDNTARIQLNHDGRSSVIVVPVAKPFFTRDSGWAAIDPE 403 ++ DG L++ ++ V ++ A SSV + DS P Sbjct: 319 IEAQDGPGLLTRAKVIVTVLDVNDNAPEFYMTSATSSV----------SEDSL-----PG 363 Query: 404 ACLNKYNLHATKLQLNNICFCLVKKKLPFDEQNSLIN 514 + +N+H N C + + LPF + S+ N Sbjct: 364 TIIGLFNVHDRDSGQNAFTTCSLPEDLPFKLEKSVDN 400
>sp|P44708|GLMS_HAEIN Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (Hexosephosphate aminotransferase) (D-fructose-6-phosphate amidotransferase) (GFAT) (L-glutamine-D-fructose-6-phosphate amidotransferase) (Glucosamine-6-phosphate synthase) Length = 610 Score = 30.4 bits (67), Expect = 5.9 Identities = 12/25 (48%), Positives = 17/25 (68%) Frame = -3 Query: 540 HNGLLENEELIREFCSSNGSFFLTR 466 HNG++EN E +RE S G FL++ Sbjct: 98 HNGIIENHEELRELLKSRGYVFLSQ 122
>sp|Q971D7|SYFA_SULTO Phenylalanyl-tRNA synthetase alpha chain (Phenylalanine--tRNA ligase alpha chain) (PheRS) Length = 469 Score = 30.0 bits (66), Expect = 7.8 Identities = 36/173 (20%), Positives = 68/173 (39%), Gaps = 5/173 (2%) Frame = +2 Query: 35 IYDPSQTLQNTNFTPRHMASVIRK--LSENSNDIQEPFQKGRLIKMSDGELKVIESLS-- 202 ++ SQ L+ + VI+ E ++E F + +L+K+ DG+ K I L Sbjct: 35 VFSISQLLKEKGYIEVEEKKVIKYELTDEGKRRLKEGFPEEKLVKLLDGKEKKIHELKDK 94 Query: 203 -ASDFEKSCKSHDGMALVSSEVKLIEVSHSDNTARIQLNHDGRSSVIVVPVAKPFFTRDS 379 DFE I + + ++++ D V+P+ K + ++ Sbjct: 95 LGRDFE------------------ISIGWAKRKGLVKIDGD-----TVIPLVKDYEAKEE 131 Query: 380 GWAAIDPEACLNKYNLHATKLQLNNICFCLVKKKLPFDEQNSLINSSFSKRPL 538 A I+PE NK +I L+ +KL ++ ++N + PL Sbjct: 132 KEALINPEKA-NK-----------DILQQLLNRKLLIKKEEKILNIRLIREPL 172
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 91,320,814 Number of Sequences: 369166 Number of extensions: 1779474 Number of successful extensions: 4029 Number of sequences better than 10.0: 7 Number of HSP's better than 10.0 without gapping: 3893 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4025 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 7666799535 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)