Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_E24
(859 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q99795|GPA33_HUMAN Cell surface A33 antigen precursor (G... 32 3.0
sp|O18735|ERBB2_CANFA Receptor tyrosine-protein kinase erbB... 32 3.0
sp|P04626|ERBB2_HUMAN Receptor tyrosine-protein kinase erbB... 32 3.0
sp|P06494|ERBB2_RAT Receptor tyrosine-protein kinase erbB-2... 32 3.0
sp|Q60553|ERBB2_MESAU Receptor tyrosine-protein kinase erbB... 31 3.9
sp|P49452|CENPC_MOUSE Centromere protein C (CENP-C) (Centro... 31 5.0
sp|Q6Q1S2|SPIKE_CVHNL Spike glycoprotein precursor (Peplome... 30 6.6
sp|P61243|YCF2_PHYPA Protein ycf2 30 6.6
sp|Q8SR66|MCES_ENCCU mRNA cap guanine-N7 methyltransferase ... 30 8.6
>sp|Q99795|GPA33_HUMAN Cell surface A33 antigen precursor (Glycoprotein A33)
Length = 319
Score = 31.6 bits (70), Expect = 3.0
Identities = 19/70 (27%), Positives = 34/70 (48%)
Frame = +2
Query: 32 PKNMKCNYSESGALFSCTSENEAVSSNPKSDYSNRKVKQNWKDVSLSTTIVAAVGCMTIL 211
P ++K +++ + CTS NE + + N V ++++ + AVG + L
Sbjct: 195 PVSLKNISTDTSGYYICTSSNEE-----GTQFCNITVAVRSPSMNVALYVGIAVGVVAAL 249
Query: 212 ISIGVSIYVC 241
I IG+ IY C
Sbjct: 250 IIIGIIIYCC 259
>sp|O18735|ERBB2_CANFA Receptor tyrosine-protein kinase erbB-2 precursor (p185erbB2)
(C-erbB-2)
Length = 1259
Score = 31.6 bits (70), Expect = 3.0
Identities = 17/43 (39%), Positives = 21/43 (48%)
Frame = +2
Query: 314 PPKPLESTFKRSFSLDDNSAYLPINQTVLTNAQGLVTMTPSPG 442
P PL+STF RS DD+ L + L QG P+PG
Sbjct: 995 PASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPEPTPG 1037
>sp|P04626|ERBB2_HUMAN Receptor tyrosine-protein kinase erbB-2 precursor (p185erbB2)
(C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type
cell surface receptor HER2) (MLN 19)
Length = 1255
Score = 31.6 bits (70), Expect = 3.0
Identities = 17/43 (39%), Positives = 21/43 (48%)
Frame = +2
Query: 314 PPKPLESTFKRSFSLDDNSAYLPINQTVLTNAQGLVTMTPSPG 442
P PL+STF RS DD+ L + L QG P+PG
Sbjct: 996 PASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPG 1038
>sp|P06494|ERBB2_RAT Receptor tyrosine-protein kinase erbB-2 precursor (p185erbB2)
(C-erbB-2) (NEU proto-oncogene) (Epidermal growth factor
receptor-related protein)
Length = 1257
Score = 31.6 bits (70), Expect = 3.0
Identities = 16/43 (37%), Positives = 22/43 (51%)
Frame = +2
Query: 314 PPKPLESTFKRSFSLDDNSAYLPINQTVLTNAQGLVTMTPSPG 442
P P++STF RS DD+ L + L QG + P+PG
Sbjct: 998 PSSPMDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFSPDPTPG 1040
>sp|Q60553|ERBB2_MESAU Receptor tyrosine-protein kinase erbB-2 precursor (p185erbB2)
(C-erbB-2) (NEU proto-oncogene)
Length = 1254
Score = 31.2 bits (69), Expect = 3.9
Identities = 17/43 (39%), Positives = 21/43 (48%)
Frame = +2
Query: 314 PPKPLESTFKRSFSLDDNSAYLPINQTVLTNAQGLVTMTPSPG 442
P PL+STF RS DD+ L + L QG P+PG
Sbjct: 996 PSSPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFFPDPAPG 1038
>sp|P49452|CENPC_MOUSE Centromere protein C (CENP-C) (Centromere autoantigen C)
Length = 906
Score = 30.8 bits (68), Expect = 5.0
Identities = 32/155 (20%), Positives = 61/155 (39%), Gaps = 2/155 (1%)
Frame = +2
Query: 83 TSENEAVSSNPKSDYSNRKVKQNWKDVSLSTTIVAAVGCMTILISIGVSIYVCHRTRXXX 262
T +++ S PK+ RK + +W++ ++S T G T+ I+ ++ C R
Sbjct: 383 TKQSQRRVSKPKAAEELRKGQSSWENSNVSNT-----GQDTLQINSKRNMKDCEEVRNEP 437
Query: 263 XXXXXXXXXXXNFFNSYPPKPLESTFKRSFSLDDNSAYLPINQTVLTNAQGLVTMTPSPG 442
+ E + K+ FS + ++P T+ + ++ PS
Sbjct: 438 NPKKQKPALENKRKTNSTQTNKEKSGKKFFSGGSKNKFVPKKVTLTSRRSRRISQRPSEW 497
Query: 443 FSINS--NSYQENPAISFINYPYTYNELSKQDSRS 541
+ + S +S NP+ N P Y KQ R+
Sbjct: 498 WRVKSDESSVDRNPS-KENNSPVVYPNKKKQTKRN 531
>sp|Q6Q1S2|SPIKE_CVHNL Spike glycoprotein precursor (Peplomer protein) (E2)
Length = 1356
Score = 30.4 bits (67), Expect = 6.6
Identities = 17/65 (26%), Positives = 29/65 (44%), Gaps = 5/65 (7%)
Frame = +2
Query: 374 YLPINQTVLTNAQGLVTMTP-----SPGFSINSNSYQENPAISFINYPYTYNELSKQDSR 538
Y P+ T L GL + T + G +N N YQ N + + Y ++ S + +
Sbjct: 252 YQPLRLTCLWPVPGLKSSTGFVYFNATGSDVNCNGYQHNSVVDVMRYNLNFSANSLDNLK 311
Query: 539 SGYLM 553
SG ++
Sbjct: 312 SGVIV 316
>sp|P61243|YCF2_PHYPA Protein ycf2
Length = 2259
Score = 30.4 bits (67), Expect = 6.6
Identities = 27/114 (23%), Positives = 54/114 (47%), Gaps = 3/114 (2%)
Frame = -3
Query: 338 KCFLKVLEDK--N*KSLIAKLLKIF*VRNSFLYDDIHKLILQ*K*ESSCIRQLQLLLWIN 165
K FL + + N L+ KIF ++N+FL +++ L + + + +L++ + +
Sbjct: 881 KTFLVIFYENFNNISKLLLYYSKIFNIQNNFLKKKLNETNLVQQIKFNIYYKLKIHFYFD 940
Query: 164 SHLSNFVLLSYYCNRI*DSTKLLHFQKYKKTMLR-ILNNCISYFLDIYMVDKFV 6
L+ L++Y+ N ++ + + + IL N SYF I M DK +
Sbjct: 941 KILTTKFLINYFNN------NQIYLESFNNNIFSLILQNQKSYFNSIQMSDKIL 988
>sp|Q8SR66|MCES_ENCCU mRNA cap guanine-N7 methyltransferase (mRNA
(guanine-N(7)-)-methyltransferase)
Length = 298
Score = 30.0 bits (66), Expect = 8.6
Identities = 14/28 (50%), Positives = 20/28 (71%), Gaps = 1/28 (3%)
Frame = -3
Query: 89 QKYKKTMLRILNNCISYFLDI-YMVDKF 9
++Y+ T+L +NNCI YF+D MVD F
Sbjct: 210 REYRFTLLDSVNNCIEYFVDFTRMVDGF 237
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,329,049
Number of Sequences: 369166
Number of extensions: 1632896
Number of successful extensions: 3799
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 3704
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3799
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8486520240
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)