Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_D05
(738 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P70569|MYO5B_RAT Myosin-5B (Myosin Vb) (Myosin heavy cha... 39 0.011
sp|Q14789|GOGB1_HUMAN Golgin subfamily B member 1 (Giantin)... 35 0.21
sp|Q9QYR6|MAP1A_MOUSE Microtubule-associated protein 1A (MA... 35 0.21
sp|P35978|KINH_STRPU Kinesin heavy chain 35 0.27
sp|Q8Y2D3|Y403_RALSO Hypothetical UPF0042 protein RSc0403 35 0.27
sp|Q8BGA5|HRB2_MOUSE HIV-1 Rev-binding protein 2 homolog 34 0.46
sp|P75434|Y344_MYCPN Hypothetical UPF0134 protein MPN344 (H... 34 0.46
sp|Q13601|HRB2_HUMAN HIV-1 Rev-binding protein 2 (Rev-inter... 34 0.46
sp|Q9U7E0|ATRX_CAEEL Transcriptional regulator ATRX homolog... 33 0.79
sp|O93308|SMC1A_XENLA Structural maintenance of chromosome ... 33 0.79
>sp|P70569|MYO5B_RAT Myosin-5B (Myosin Vb) (Myosin heavy chain myr 6)
Length = 1846
Score = 39.3 bits (90), Expect = 0.011
Identities = 52/212 (24%), Positives = 90/212 (42%), Gaps = 33/212 (15%)
Frame = +3
Query: 21 AYPLTPIRKEVSDIKISVPKASTAREV----------QLIRRDIDFVRANAYAAKSA--- 161
A P +++EV ++ + KA + R V +L +R D NA
Sbjct: 977 ADPSLQLQEEVQSLRTELQKAHSERRVLEDAHNRENGELRKRVADLEHENALLKDEKEHL 1036
Query: 162 --RLKRYSSADSLLINQNTEKEKKVKKPGELPSYLIKRRNQWKEEEQLF--IQNQPDPDQ 329
++ R S A+S + E+ +KK EL + +N KE QL +N D Q
Sbjct: 1037 NHQILRQSKAESS--QSSVEENLLIKK--ELEEERSRYQNLVKEYSQLEQRYENLRDEQQ 1092
Query: 330 PPGHRKMPEKE----------RIATLELLKASEKDMLTELGRLPIR------TDTLKLRT 461
PGHRK P + I+T E+ +D L ++ + I T LKL+
Sbjct: 1093 TPGHRKNPSNQSSLESDSNYPSISTSEI--GDTEDALQQVEEIGIEKAAMDMTVFLKLQK 1150
Query: 462 KKQEIEQKLNELEEAIKIFSKPKVFVRIDD*N 557
+ +E+EQ+ +L+ ++ + V+++ N
Sbjct: 1151 RVRELEQERKKLQVQLEKEQQDSKKVQVEQQN 1182
>sp|Q14789|GOGB1_HUMAN Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi
complex-associated protein) (GCP372)
Length = 3259
Score = 35.0 bits (79), Expect = 0.21
Identities = 35/124 (28%), Positives = 62/124 (50%), Gaps = 6/124 (4%)
Frame = +3
Query: 177 SSADSL---LINQNTEKEKKVKKPGELPSYLIKRRNQWKEEEQLFIQNQPDPDQPPGHRK 347
SS +SL L +KEK VK+ L S I +W+E+ + +Q + +
Sbjct: 1567 SSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHK-ELQKEYEILLQSYENV 1625
Query: 348 MPEKERIA-TLELLKASEKDMLTELGRLPIRTDTLKLRTKK--QEIEQKLNELEEAIKIF 518
E ERI +E ++ ++++ +L T+ K T+K QE EQ++ E++E ++ F
Sbjct: 1626 SNEAERIQHVVEAVRQEKQELYGKLR----STEANKKETEKQLQEAEQEMEEMKEKMRKF 1681
Query: 519 SKPK 530
+K K
Sbjct: 1682 AKSK 1685
>sp|Q9QYR6|MAP1A_MOUSE Microtubule-associated protein 1A (MAP 1A)
Length = 1021
Score = 35.0 bits (79), Expect = 0.21
Identities = 36/149 (24%), Positives = 67/149 (44%), Gaps = 12/149 (8%)
Frame = +3
Query: 93 REVQLIRRDIDFVRANAYAAKSARLK------RYSSADSLLINQNTEKEKKVKKPGELPS 254
R + +R + + A A A LK R S +SL T K K+ L
Sbjct: 508 RHLDFLRYPVATQKDLAAGAVPANLKPSKIKHRADSKESLKAAPKTAMSKLAKREEVLEE 567
Query: 255 YLIKRRNQWKEEEQLFIQNQPDP-DQPPGHRKMPEKERIATLELLKASEKDMLTE-LGRL 428
+ R++ +E + +P ++PP PE+ R + E LKA ++ ++ + +G+
Sbjct: 568 GAKEARSELAKELAKSEKKAKEPSEKPPEKPSKPERVRTESSEALKAEKRKLIKDKVGKK 627
Query: 429 PIRTDTLKLRTK----KQEIEQKLNELEE 503
++ KL K K+EI+++ EL++
Sbjct: 628 HLKEKISKLEEKRDKEKKEIKKERKELKK 656
>sp|P35978|KINH_STRPU Kinesin heavy chain
Length = 1031
Score = 34.7 bits (78), Expect = 0.27
Identities = 30/123 (24%), Positives = 64/123 (52%), Gaps = 12/123 (9%)
Frame = +3
Query: 165 LKRYSSADSLLI----NQNTEKEKKVKKPGELPSYLI-KRRNQWKEEE-QLFIQNQPDPD 326
L+R+ + +S+ + N+N E K++ KP ++ ++ + +N+W+EE+ +L+ Q
Sbjct: 365 LQRWRAGESVPVKEQGNKNDEILKEMMKPKQMTVHVSEEEKNKWEEEKVKLYEQLDEKDS 424
Query: 327 QPPGHRKMPEK---ERIATLELLKASEKD---MLTELGRLPIRTDTLKLRTKKQEIEQKL 488
+ ++ EK + + ELL + ++D + +++GRL K K E+ Q L
Sbjct: 425 EIDNQSRLTEKLKQQMLEQEELLSSMQRDYELLQSQMGRLEAENAAAKEEAK--EVLQAL 482
Query: 489 NEL 497
E+
Sbjct: 483 EEM 485
>sp|Q8Y2D3|Y403_RALSO Hypothetical UPF0042 protein RSc0403
Length = 296
Score = 34.7 bits (78), Expect = 0.27
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Frame = +3
Query: 258 LIKRRNQWKEEEQLFIQN-QPDPDQPPGHRKMPEKERIATLELLKASEKDMLTELGRLPI 434
L++R ++ + L I+N +PD PP K P+ I +E+ E+++L+ L
Sbjct: 92 LVQRYSETRRRHPLSIRNGRPDAGNPPSAAKGPDTSLIEAIEM----ERELLSPLADPAH 147
Query: 435 RTDTLKLRT 461
R DT LRT
Sbjct: 148 RIDTSTLRT 156
>sp|Q8BGA5|HRB2_MOUSE HIV-1 Rev-binding protein 2 homolog
Length = 380
Score = 33.9 bits (76), Expect = 0.46
Identities = 31/114 (27%), Positives = 50/114 (43%)
Frame = +3
Query: 144 YAAKSARLKRYSSADSLLINQNTEKEKKVKKPGELPSYLIKRRNQWKEEEQLFIQNQPDP 323
Y K+ +KR + DS L +Q+ E+ LP + K N+ KE ++ ++ + P
Sbjct: 216 YNIKTLMIKRELAKDSELRSQSWERF--------LPQFKHKNVNKRKEPKKKSVKKEYTP 267
Query: 324 DQPPGHRKMPEKERIATLELLKASEKDMLTELGRLPIRTDTLKLRTKKQEIEQK 485
PP +KE + LKAS+K I+ + TK+QE K
Sbjct: 268 FPPPQPESQIDKELASGEYFLKASQK---KRQKMEAIKAKQAEALTKRQEERNK 318
>sp|P75434|Y344_MYCPN Hypothetical UPF0134 protein MPN344 (H91_orf216)
Length = 216
Score = 33.9 bits (76), Expect = 0.46
Identities = 40/155 (25%), Positives = 71/155 (45%), Gaps = 10/155 (6%)
Frame = +3
Query: 72 VPKASTAREVQLIRR-------DIDFVRANAYAAKSARLKRYSSADSLLINQNTEKEKKV 230
+PK + R+ ++R+ I + + K+A+ + D +I +++ +
Sbjct: 1 MPKIISKRKFNILRKTKEEIFSQIVYTKKRNGLHKAAKEYYFKDKDFTIIE---DQQDRP 57
Query: 231 KKPGELPSYLI-KRRNQWKEEEQLFIQNQPD-PDQP-PGHRKMPEKERIATLELLKASEK 401
KP EL + I K K +Q QP PD P G++KMP+ + T L+ +K
Sbjct: 58 DKPEELDTPDIPKPPKPPKGPDQPEEPGQPGGPDDPNSGNKKMPKPDEFVTHRQLQEFKK 117
Query: 402 DMLTELGRLPIRTDTLKLRTKKQEIEQKLNELEEA 506
D+L EL + LK +K ++ L EL++A
Sbjct: 118 DLLVELHEIFPTKPELKRVEEKVDV---LFELQKA 149
>sp|Q13601|HRB2_HUMAN HIV-1 Rev-binding protein 2 (Rev-interacting protein 1) (Rip-1)
Length = 381
Score = 33.9 bits (76), Expect = 0.46
Identities = 35/129 (27%), Positives = 54/129 (41%)
Frame = +3
Query: 144 YAAKSARLKRYSSADSLLINQNTEKEKKVKKPGELPSYLIKRRNQWKEEEQLFIQNQPDP 323
Y KS +KR + DS L +Q+ E+ LP + K N+ KE ++ ++ + P
Sbjct: 217 YNIKSLMIKRELAKDSELRSQSWERF--------LPQFKHKNVNKRKEPKKKTVKKEYTP 268
Query: 324 DQPPGHRKMPEKERIATLELLKASEKDMLTELGRLPIRTDTLKLRTKKQEIEQKLNELEE 503
PP +KE + LKA++K R ++ K+ E K EE
Sbjct: 269 FPPPQPESQIDKELASGEYFLKANQKK----------RQKMEAIKAKQAEAISK--RQEE 316
Query: 504 AIKIFSKPK 530
K F PK
Sbjct: 317 RNKAFIPPK 325
>sp|Q9U7E0|ATRX_CAEEL Transcriptional regulator ATRX homolog (X-linked nuclear protein 1)
Length = 1359
Score = 33.1 bits (74), Expect = 0.79
Identities = 30/129 (23%), Positives = 57/129 (44%)
Frame = +3
Query: 117 DIDFVRANAYAAKSARLKRYSSADSLLINQNTEKEKKVKKPGELPSYLIKRRNQWKEEEQ 296
D D R KS + K+ +S++S ++ +E+E+KVKK + +K+R + EE
Sbjct: 131 DSDEEREQKSKKKSKKTKKQTSSES---SEESEEERKVKKSKKNKEKSVKKRAETSEES- 186
Query: 297 LFIQNQPDPDQPPGHRKMPEKERIATLELLKASEKDMLTELGRLPIRTDTLKLRTKKQEI 476
D D+ P + ++ A E SE + + K + K +++
Sbjct: 187 -------DEDEKPSKKSKKGLKKKAKSESESESEDE-----------KEVKKSKKKSKKV 228
Query: 477 EQKLNELEE 503
+K +E E+
Sbjct: 229 VKKESESED 237
>sp|O93308|SMC1A_XENLA Structural maintenance of chromosome 1 protein (xSMC1)
Length = 1232
Score = 33.1 bits (74), Expect = 0.79
Identities = 38/168 (22%), Positives = 83/168 (49%), Gaps = 11/168 (6%)
Frame = +3
Query: 69 SVPKASTAREVQLIRRDIDFVRANAYAAKSARLKRYSSADSLLINQNTEKEKKVKKPGEL 248
++ K ++ +L ++ +++A S ++K++ +A L N + +K+ EL
Sbjct: 279 AIEKEIKEKDAELNQKLPQYIKAKENP--SHKIKKFRAAKKSLQNAQKQYKKRKADMDEL 336
Query: 249 PSYLI---KRRNQWKEEEQLFIQNQP-----DPDQPPGHRKMPEK--ERIATL-ELLKAS 395
++ K R +++E + Q+Q + +Q + ++ E+ +R ATL + L+
Sbjct: 337 EKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKF 396
Query: 396 EKDMLTELGRLPIRTDTLKLRTKKQEIEQKLNELEEAIKIFSKPKVFV 539
+D + RL + + K+ T+ + I+QKL ELEE K K + ++
Sbjct: 397 NRDQKADQDRLDLE-ERKKVETEAK-IKQKLRELEENQKRIEKLEEYI 442
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,221,074
Number of Sequences: 369166
Number of extensions: 1095037
Number of successful extensions: 4355
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4082
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4329
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6631293200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)