Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_B23
(532 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q01105|SET_HUMAN SET protein (Phosphatase 2A inhibitor I... 84 2e-16
sp|Q9EQU5|SET_MOUSE SET protein (Phosphatase 2A inhibitor I... 84 2e-16
sp|Q63945|SET_RAT SET protein (Phosphatase 2A inhibitor I2P... 84 2e-16
sp|Q18240|SPR2_CAEEL Suppressor of presenilin 2 79 5e-15
sp|P53997|SET_DROME SET protein 79 5e-15
sp|O88852|TSYL1_MOUSE Testis-specific Y-encoded-like protei... 58 1e-08
sp|Q9H0U9|TSYL1_HUMAN Testis-specific Y-encoded-like protei... 57 2e-08
sp|P13825|ASP_PLAFS Aspartic acid-rich protein precursor 54 3e-07
sp|Q9UJ04|TSYL4_HUMAN Testis-specific Y-encoded-like protei... 51 2e-06
sp|Q9H489|TSY3_HUMAN Testis-specific Y-encoded-like protein... 50 4e-06
>sp|Q01105|SET_HUMAN SET protein (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A)
(Template-activating factor I) (TAF-I) (HLA-DR
associated protein II) (PHAPII) (Inhibitor of granzyme
A-activated DNase) (IGAAD)
Length = 290
Score = 84.3 bits (207), Expect = 2e-16
Identities = 44/106 (41%), Positives = 57/106 (53%), Gaps = 1/106 (0%)
Frame = +3
Query: 3 IKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEGKNFVKSLNESLNXX 179
IKSG++I F N YF N ++K H+ ES + + + WK GK+ K +++ N
Sbjct: 131 IKSGYRIDFYFDENPYFENKVLSKEFHLNESGDPSSKSTEIKWKSGKDLTKRSSQTQNKA 190
Query: 180 XXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 317
P SF WFT ELGEVIKDD+WPNPLQYYL
Sbjct: 191 SRKRQHEE--PESFFTWFTDHSDAGADELGEVIKDDIWPNPLQYYL 234
>sp|Q9EQU5|SET_MOUSE SET protein (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A)
(Template-activating factor I) (TAF-I)
Length = 289
Score = 84.3 bits (207), Expect = 2e-16
Identities = 44/106 (41%), Positives = 57/106 (53%), Gaps = 1/106 (0%)
Frame = +3
Query: 3 IKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEGKNFVKSLNESLNXX 179
IKSG++I F N YF N ++K H+ ES + + + WK GK+ K +++ N
Sbjct: 130 IKSGYRIDFYFDENPYFENKVLSKEFHLNESGDPSSKSTEIKWKSGKDLTKRSSQTQNKA 189
Query: 180 XXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 317
P SF WFT ELGEVIKDD+WPNPLQYYL
Sbjct: 190 SRKRQHEE--PESFFTWFTDHSDAGADELGEVIKDDIWPNPLQYYL 233
>sp|Q63945|SET_RAT SET protein (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A)
(Template-activating factor I) (TAF-I) (Liver
regeneration-related protein LRRGR00002)
Length = 289
Score = 84.3 bits (207), Expect = 2e-16
Identities = 44/106 (41%), Positives = 57/106 (53%), Gaps = 1/106 (0%)
Frame = +3
Query: 3 IKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEGKNFVKSLNESLNXX 179
IKSG++I F N YF N ++K H+ ES + + + WK GK+ K +++ N
Sbjct: 130 IKSGYRIDFYFDENPYFENKVLSKEFHLNESGDPSSKSTEIKWKSGKDLTKRSSQTQNKA 189
Query: 180 XXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 317
P SF WFT ELGEVIKDD+WPNPLQYYL
Sbjct: 190 SRKRQHEE--PESFFTWFTDHSDAGADELGEVIKDDIWPNPLQYYL 233
>sp|Q18240|SPR2_CAEEL Suppressor of presenilin 2
Length = 312
Score = 79.3 bits (194), Expect = 5e-15
Identities = 42/105 (40%), Positives = 53/105 (50%)
Frame = +3
Query: 3 IKSGFKIIMTFSPNEYFNNTTITKSIHVGESEIKTTCDPVDWKEGKNFVKSLNESLNXXX 182
++SGFKIIMTF PNEYF N ITKS H+ T ++WKE K
Sbjct: 117 LRSGFKIIMTFDPNEYFTNEVITKSYHLQSESPSTEITEIEWKENKK------------- 163
Query: 183 XXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 317
+F++W T E+ EVIKDDL+ NPLQYY+
Sbjct: 164 PPFPEDGDSAHTFLEWLTYAALPDSDEIAEVIKDDLYVNPLQYYV 208
>sp|P53997|SET_DROME SET protein
Length = 269
Score = 79.3 bits (194), Expect = 5e-15
Identities = 43/112 (38%), Positives = 56/112 (50%), Gaps = 7/112 (6%)
Frame = +3
Query: 3 IKSGFKIIMTFSPNEYFNNTTITKSIHVGESEIK-------TTCDPVDWKEGKNFVKSLN 161
IKSG++I F N YF N +TK H+ + +T P+ WKEGKN +K L
Sbjct: 119 IKSGYRINFHFDENPYFENKVLTKEFHLNSAAASENGDWPASTSTPIKWKEGKNLLKLL- 177
Query: 162 ESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 317
L +F WF+ + E+ E+IKDDLWPNPLQYYL
Sbjct: 178 --LTKPYGNKKKRNSEYKTFFDWFSDNTDPVNDEIAELIKDDLWPNPLQYYL 227
>sp|O88852|TSYL1_MOUSE Testis-specific Y-encoded-like protein 1 (TSPY-like 1)
Length = 379
Score = 58.2 bits (139), Expect = 1e-08
Identities = 34/108 (31%), Positives = 49/108 (45%), Gaps = 4/108 (3%)
Frame = +3
Query: 6 KSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEG---KNFVKSLNESLN 173
K+G K F N YF N I K V S + + P+ W+ G ++F++ + +
Sbjct: 258 KTGCKFKFFFRRNPYFRNKLIVKEYEVRSSGRVVSLSTPIIWRRGHEPQSFIRRNQDLI- 316
Query: 174 XXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 317
SF WF+ + E+IK+DLWPNPLQYYL
Sbjct: 317 -------------CSFFTWFSDHSLPESDRIAEIIKEDLWPNPLQYYL 351
>sp|Q9H0U9|TSYL1_HUMAN Testis-specific Y-encoded-like protein 1 (TSPY-like 1)
Length = 438
Score = 57.4 bits (137), Expect = 2e-08
Identities = 33/108 (30%), Positives = 50/108 (46%), Gaps = 4/108 (3%)
Frame = +3
Query: 6 KSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEG---KNFVKSLNESLN 173
++G K F N YF N I K V S + + P+ W+ G ++F++ + +
Sbjct: 317 RTGCKFKFFFRRNPYFRNKLIVKEYEVRSSGRVVSLSTPIIWRRGHEPQSFIRRNQDLI- 375
Query: 174 XXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 317
SF WF+ ++ E+IK+DLWPNPLQYYL
Sbjct: 376 -------------CSFFTWFSDHSLPESDKIAEIIKEDLWPNPLQYYL 410
>sp|P13825|ASP_PLAFS Aspartic acid-rich protein precursor
Length = 253
Score = 53.5 bits (127), Expect = 3e-07
Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 3/106 (2%)
Frame = +3
Query: 15 FKIIMTFSPN--EYFNNTTITKSIHVGESEIKTT-CDPVDWKEGKNFVKSLNESLNXXXX 185
+KI F E+ T+ K + ++ K C + WKEGKN + ++ + +
Sbjct: 103 YKITFIFGEKAKEFMEPLTLVKHVTFDNNQEKVVECTRIKWKEGKNPIAAVTHNRSDLDN 162
Query: 186 XXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYLAV 323
S +WFT+D ++GE+I+ ++W NPL YYL +
Sbjct: 163 EIPKW-----SIFEWFTTDELQDKPDVGELIRREIWHNPLSYYLGL 203
>sp|Q9UJ04|TSYL4_HUMAN Testis-specific Y-encoded-like protein 4 (TSPY-like 4)
Length = 414
Score = 50.8 bits (120), Expect = 2e-06
Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 1/105 (0%)
Frame = +3
Query: 6 KSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEGKNFVKSLNESLNXXX 182
++G K F N YF N + K S + + P+ W G++ ++ +
Sbjct: 291 RAGCKFKFIFQGNPYFRNEGLVKEYERRSSGRVVSLSTPIRWHRGQDPQAHIHRNREGNT 350
Query: 183 XXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 317
SF WF+ + E+IK +LWPNPLQYYL
Sbjct: 351 IP---------SFFNWFSDHSLLEFDRIAEIIKGELWPNPLQYYL 386
>sp|Q9H489|TSY3_HUMAN Testis-specific Y-encoded-like protein 3 (TSPY-like 3)
Length = 355
Score = 49.7 bits (117), Expect = 4e-06
Identities = 30/105 (28%), Positives = 44/105 (41%), Gaps = 1/105 (0%)
Frame = +3
Query: 6 KSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEGKNFVKSLNESLNXXX 182
++G K F N YF N I K S + + + W G+ ++ + +
Sbjct: 233 RTGCKFKFRFWSNPYFQNKVIVKEYECRASGRVVSIATRIRWHWGQEPPALVHRNRDTVR 292
Query: 183 XXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 317
SF WF+ + ++IKDDLWPNPLQYYL
Sbjct: 293 -----------SFFSWFSQHSLPEADRVAQIIKDDLWPNPLQYYL 326
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,186,368
Number of Sequences: 369166
Number of extensions: 785965
Number of successful extensions: 1805
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1767
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1787
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3600891075
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)