Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_B07
(783 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5RE33|DP1_PONPY Polyposis locus protein 1 homolog 176 6e-44
sp|Q60870|DP1_MOUSE Polyposis locus protein 1 homolog (TB2 ... 173 4e-43
sp|Q4WTW3|YOP1_ASPFU Protein yopA 112 9e-25
sp|Q871R7|YOP1_NEUCR Protein yop-1 110 6e-24
sp|Q6CP93|YOP1_KLULA Protein YOP1 107 5e-23
sp|Q51VY4|YOP1_MAGGR Protein YOP1 107 5e-23
sp|Q4P0H0|YOP1_USTMA Protein YOP1 105 2e-22
sp|Q9UU91|YOP1_SCHPO Protein yop1 104 3e-22
sp|Q6BWH8|YOP1_DEBHA Protein YOP1 102 9e-22
sp|Q12402|YOP1_YEAST Protein YOP1 (YIP1 partner protein 1) ... 102 2e-21
>sp|Q5RE33|DP1_PONPY Polyposis locus protein 1 homolog
Length = 189
Score = 176 bits (446), Expect = 6e-44
Identities = 83/175 (47%), Positives = 119/175 (68%)
Frame = +3
Query: 63 KEKLEIYLNKKNAFTDFLNQVEEKTKVKKIYMAIGLITFVIGYLIFGYAGQFLANFIGFL 242
+E+ + +L++KN TD L ++E KT V + ++A+G+I V YL+FGY L N IGF
Sbjct: 6 RERFDRFLHEKNCMTDLLAKLEAKTGVNRSFIALGVIGLVALYLVFGYGASLLCNLIGFG 65
Query: 243 FPAYWSIKAIETPAKDDDTKWLTYWVVYAAFSLVESVTDIFLSWIPLYALLKCVFLIYLM 422
+PAY SIKAIE+P K+DDT+WLTYWVVY FS+ E +DIFLSW P Y +LKC FL++ M
Sbjct: 66 YPAYISIKAIESPNKEDDTQWLTYWVVYGVFSIAEFFSDIFLSWFPFYYMLKCGFLLWCM 125
Query: 423 VPTKWNGSIYIYYSFIRPYILKNQTKIDEVLSKTTNATKDIFNKVSETGEAYVKE 587
P+ NG+ +Y IRP+ LK+++++D V+ KD+ +K ET +A KE
Sbjct: 126 APSPSNGAELLYKRIIRPFFLKHESQVDSVV-------KDLKDKAKETADAITKE 173
>sp|Q60870|DP1_MOUSE Polyposis locus protein 1 homolog (TB2 protein homolog) (GP106)
Length = 185
Score = 173 bits (439), Expect = 4e-43
Identities = 81/175 (46%), Positives = 119/175 (68%)
Frame = +3
Query: 63 KEKLEIYLNKKNAFTDFLNQVEEKTKVKKIYMAIGLITFVIGYLIFGYAGQFLANFIGFL 242
+E+ + +L++KN TD L ++E KT V + ++A+G+I V YL+FGY L N IGF
Sbjct: 2 RERFDRFLHEKNCMTDLLAKLEAKTGVNRSFIALGVIGLVALYLVFGYGASLLCNLIGFG 61
Query: 243 FPAYWSIKAIETPAKDDDTKWLTYWVVYAAFSLVESVTDIFLSWIPLYALLKCVFLIYLM 422
+PAY S+KAIE+P KDDDT+WLTYWVVY FS+ E +D+FLSW+P Y +LKC FL++ M
Sbjct: 62 YPAYISMKAIESPNKDDDTQWLTYWVVYGVFSIAEFFSDLFLSWLPFYYMLKCGFLLWCM 121
Query: 423 VPTKWNGSIYIYYSFIRPYILKNQTKIDEVLSKTTNATKDIFNKVSETGEAYVKE 587
P+ NG+ +Y IRP L++++++D V+ KD+ +K ET +A KE
Sbjct: 122 APSPANGAEMLYRRIIRPIFLRHESQVDSVV-------KDVKDKAKETADAISKE 169
>sp|Q4WTW3|YOP1_ASPFU Protein yopA
Length = 169
Score = 112 bits (281), Expect = 9e-25
Identities = 53/133 (39%), Positives = 85/133 (63%)
Frame = +3
Query: 84 LNKKNAFTDFLNQVEEKTKVKKIYMAIGLITFVIGYLIFGYAGQFLANFIGFLFPAYWSI 263
L+K+ + LN +E +T V K+Y+ +GL+ + F AG+FL NF GFL P Y+S+
Sbjct: 15 LDKELSKYPVLNNLERQTSVPKVYVILGLVGIYTFLVFFNIAGEFLVNFAGFLIPGYYSL 74
Query: 264 KAIETPAKDDDTKWLTYWVVYAAFSLVESVTDIFLSWIPLYALLKCVFLIYLMVPTKWNG 443
A+ T K DDT+WLTYWVVYA ++VES + W P Y + K V ++++ +P + NG
Sbjct: 75 NALFTSGKADDTQWLTYWVVYALLTVVESAINA-AYWFPFYYIFKFVLILWMSLP-QTNG 132
Query: 444 SIYIYYSFIRPYI 482
+ +++SF++P +
Sbjct: 133 AQVVFHSFLQPVL 145
>sp|Q871R7|YOP1_NEUCR Protein yop-1
Length = 168
Score = 110 bits (274), Expect = 6e-24
Identities = 54/131 (41%), Positives = 82/131 (62%)
Frame = +3
Query: 84 LNKKNAFTDFLNQVEEKTKVKKIYMAIGLITFVIGYLIFGYAGQFLANFIGFLFPAYWSI 263
L+K+ + LN +E+ T V K Y IGL+ +IF GQ L N GF+ P Y+S+
Sbjct: 15 LDKELSKYPTLNNLEKTTGVPKAYAVIGLVALYFFLIIFNLGGQLLTNLAGFVLPGYYSL 74
Query: 264 KAIETPAKDDDTKWLTYWVVYAAFSLVESVTDIFLSWIPLYALLKCVFLIYLMVPTKWNG 443
A+ T +K DDT+WLTYWVV++ F+++ES+ + + W P Y K VFL++L +PT + G
Sbjct: 75 NALFTASKQDDTQWLTYWVVFSLFTVIESLISV-VYWFPFYFTFKFVFLLWLSLPT-FKG 132
Query: 444 SIYIYYSFIRP 476
+ I+ SF+ P
Sbjct: 133 AETIFRSFLAP 143
>sp|Q6CP93|YOP1_KLULA Protein YOP1
Length = 180
Score = 107 bits (266), Expect = 5e-23
Identities = 50/147 (34%), Positives = 92/147 (62%), Gaps = 2/147 (1%)
Frame = +3
Query: 45 EYFNTYKEKLEIYLNKKNAFTDFLNQVEEKTKVKKIYMAIGLIT--FVIGYLIFGYAGQF 218
+Y +++ L+ L+ K A L+++E +TK+ + Y+ +GL+ F++ ++ G G+
Sbjct: 3 DYLKLFQDSLK-GLDTKFAGNQILSRIEAQTKLPRSYVIVGLVAVYFLLIFINVGGIGEI 61
Query: 219 LANFIGFLFPAYWSIKAIETPAKDDDTKWLTYWVVYAAFSLVESVTDIFLSWIPLYALLK 398
L+NF+GF P Y+S+KA++T DDT+ LTYW+V++ S++E + L W+P Y K
Sbjct: 62 LSNFVGFCIPTYYSLKALKTATSTDDTQLLTYWIVFSFLSVIEFWSKAILYWVPFYWFFK 121
Query: 399 CVFLIYLMVPTKWNGSIYIYYSFIRPY 479
VFL+Y+ +P+ + G+ +Y I P+
Sbjct: 122 TVFLLYIAIPS-FGGAQLVYTRLISPF 147
>sp|Q51VY4|YOP1_MAGGR Protein YOP1
Length = 170
Score = 107 bits (266), Expect = 5e-23
Identities = 54/146 (36%), Positives = 86/146 (58%), Gaps = 4/146 (2%)
Frame = +3
Query: 114 LNQVEEKTKVKKIYMAIGLITFVIGYLIFGYAGQFLANFIGFLFPAYWSIKAIETPAKDD 293
LN +E T V K Y +G++ ++F GQ L N GF PAY+S+ A+ + K+D
Sbjct: 25 LNNLERTTGVPKAYAVVGVVVLYFFLIVFNLGGQLLTNIAGFGIPAYYSLDALFSANKED 84
Query: 294 DTKWLTYWVVYAAFSLVESVTDIFLSWIPLYALLKCVFLIYLMVPTKWNGSIYIYYSFIR 473
DT+WLTYWVV+A F++VES+ + + W P Y + K VFL++L +P + G+ I+ SF+
Sbjct: 85 DTQWLTYWVVFAMFTVVESLVSV-VYWFPFYYMFKFVFLLWLSLPA-FKGADIIFRSFLA 142
Query: 474 P----YILKNQTKIDEVLSKTTNATK 539
P Y + ++ + +K +A K
Sbjct: 143 PTLSRYFVHSRPASSNLRAKADSAGK 168
>sp|Q4P0H0|YOP1_USTMA Protein YOP1
Length = 172
Score = 105 bits (261), Expect = 2e-22
Identities = 54/160 (33%), Positives = 91/160 (56%), Gaps = 3/160 (1%)
Frame = +3
Query: 63 KEKLEIY---LNKKNAFTDFLNQVEEKTKVKKIYMAIGLITFVIGYLIFGYAGQFLANFI 233
++K+E + ++K+ + L + E+ V K Y A+G ++ F A FL N +
Sbjct: 9 QQKVEYFVAQIDKELSRYPALKKFEQTVPVPKAYAALGAFGIFTLFVFFNIAAGFLTNLL 68
Query: 234 GFLFPAYWSIKAIETPAKDDDTKWLTYWVVYAAFSLVESVTDIFLSWIPLYALLKCVFLI 413
GF PAY+S+KA+E+P DD +WLTYWVV+ F+ +E+ +I L +IP Y +K + ++
Sbjct: 69 GFFVPAYFSLKALESPQPQDDIQWLTYWVVFGLFTFLETFINIVLYYIPWYYTIKTLAIV 128
Query: 414 YLMVPTKWNGSIYIYYSFIRPYILKNQTKIDEVLSKTTNA 533
+LM+P + G+ +Y IRP L Q + + + T A
Sbjct: 129 WLMLP-QTQGAKMVYSRIIRPVFLTTQKTVHQANASTPAA 167
>sp|Q9UU91|YOP1_SCHPO Protein yop1
Length = 182
Score = 104 bits (259), Expect = 3e-22
Identities = 57/157 (36%), Positives = 93/157 (59%)
Frame = +3
Query: 63 KEKLEIYLNKKNAFTDFLNQVEEKTKVKKIYMAIGLITFVIGYLIFGYAGQFLANFIGFL 242
K+ ++ N+ AF LN +E+ V K+Y+ + +L + G L N + F
Sbjct: 8 KQNMQDLDNRLAAFPQ-LNSLEKNFGVSKLYVFLTAAGIYALFLFLNWGGFLLTNLLAFA 66
Query: 243 FPAYWSIKAIETPAKDDDTKWLTYWVVYAAFSLVESVTDIFLSWIPLYALLKCVFLIYLM 422
PA++SI AIET K DDT+WLTY++V + +++E + + L ++P+Y LLK +FLI+L
Sbjct: 67 MPAFFSINAIETTNKADDTQWLTYYLVTSFLNVIEYWSQLILYYVPVYWLLKAIFLIWLA 126
Query: 423 VPTKWNGSIYIYYSFIRPYILKNQTKIDEVLSKTTNA 533
+P K+NG+ IY IRPYI + +I + +S+ A
Sbjct: 127 LP-KFNGATIIYRHLIRPYITPHVIRICKSVSRQNAA 162
>sp|Q6BWH8|YOP1_DEBHA Protein YOP1
Length = 177
Score = 102 bits (255), Expect = 9e-22
Identities = 59/174 (33%), Positives = 94/174 (54%), Gaps = 2/174 (1%)
Frame = +3
Query: 42 MEYFNTYKEKLEIYLNKKNAFTDFLNQVEEKTKVKKIYMAIGL--ITFVIGYLIFGYAGQ 215
M Y N K L +++K L Q E KT + + Y +G + FV+ +L G GQ
Sbjct: 1 MSYQNQAKSFLST-IDEKTKDLQILRQFELKTGLPRSYAILGGFGLYFVLIFLNIGGVGQ 59
Query: 216 FLANFIGFLFPAYWSIKAIETPAKDDDTKWLTYWVVYAAFSLVESVTDIFLSWIPLYALL 395
L+N G + P Y+S+ A+E+ DDT+ LTYWVV+A F++VE + L WIP Y L
Sbjct: 60 LLSNIAGLVIPGYFSLLALESTTTSDDTQLLTYWVVFATFNVVEFWSKAILYWIPFYYLF 119
Query: 396 KCVFLIYLMVPTKWNGSIYIYYSFIRPYILKNQTKIDEVLSKTTNATKDIFNKV 557
K VFL+Y+ +P+ G++ +Y + I+P+ + + NA + + + V
Sbjct: 120 KTVFLVYIGIPST-GGAVTVYNAAIKPFSRRYIVNNKKFAQDINNAAQGVSSSV 172
>sp|Q12402|YOP1_YEAST Protein YOP1 (YIP1 partner protein 1) (Ypt-interacting protein 2)
Length = 180
Score = 102 bits (253), Expect = 2e-21
Identities = 64/174 (36%), Positives = 100/174 (57%), Gaps = 9/174 (5%)
Frame = +3
Query: 45 EYFNTYKEKLEIYLNKKNAFTDFLNQVEEKTKVKKIYMAIGLITFVIGYLIF---GYAGQ 215
EY ++ +++ + + K + L Q+E KT + K Y+ GL F LIF G G+
Sbjct: 3 EYASSIHSQMKQF-DTKYSGNRILQQLENKTNLPKSYLVAGL-GFAYLLLIFINVGGVGE 60
Query: 216 FLANFIGFLFPAYWSIKAIETPAKDDDTKWLTYWVVYAAFSLVESVTDIFLSWIPLYALL 395
L+NF GF+ PAY S+ A++TP DDT+ LTYW+V++ S++E + L IP Y L
Sbjct: 61 ILSNFAGFVLPAYLSLVALKTPTSTDDTQLLTYWIVFSFLSVIEFWSKAILYLIPFYWFL 120
Query: 396 KCVFLIYLMVPTKWNGSIYIYYSFIRP----YILK--NQTKIDEVLSKTTNATK 539
K VFLIY+ +P + G+ IY + P YIL+ ++T+ DE+ + A+K
Sbjct: 121 KTVFLIYIALP-QTGGARMIYQKIVAPLTDRYILRDVSKTEKDEIRASVNEASK 173
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,615,179
Number of Sequences: 369166
Number of extensions: 1792160
Number of successful extensions: 5181
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4969
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5158
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7357347200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)