Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_A24
(564 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q01105|SET_HUMAN SET protein (Phosphatase 2A inhibitor I... 94 2e-19
sp|Q9EQU5|SET_MOUSE SET protein (Phosphatase 2A inhibitor I... 94 2e-19
sp|Q63945|SET_RAT SET protein (Phosphatase 2A inhibitor I2P... 94 2e-19
sp|P53997|SET_DROME SET protein 92 7e-19
sp|Q18240|SPR2_CAEEL Suppressor of presenilin 2 91 2e-18
sp|O88852|TSYL1_MOUSE Testis-specific Y-encoded-like protei... 62 1e-09
sp|Q9H0U9|TSYL1_HUMAN Testis-specific Y-encoded-like protei... 61 2e-09
sp|P13825|ASP_PLAFS Aspartic acid-rich protein precursor 58 2e-08
sp|Q9UJ04|TSYL4_HUMAN Testis-specific Y-encoded-like protei... 57 4e-08
sp|Q9H489|TSY3_HUMAN Testis-specific Y-encoded-like protein... 54 3e-07
>sp|Q01105|SET_HUMAN SET protein (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A)
(Template-activating factor I) (TAF-I) (HLA-DR
associated protein II) (PHAPII) (Inhibitor of granzyme
A-activated DNase) (IGAAD)
Length = 290
Score = 94.0 bits (232), Expect = 2e-19
Identities = 48/114 (42%), Positives = 64/114 (56%), Gaps = 1/114 (0%)
Frame = +2
Query: 11 LDVEEFDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEGKNFVKS 187
++V EF+DIKSG++I F N YF N ++K H+ ES + + + WK GK+ K
Sbjct: 123 VEVTEFEDIKSGYRIDFYFDENPYFENKVLSKEFHLNESGDPSSKSTEIKWKSGKDLTKR 182
Query: 188 LNESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 349
+++ N P SF WFT ELGEVIKDD+WPNPLQYYL
Sbjct: 183 SSQTQNKASRKRQHEE--PESFFTWFTDHSDAGADELGEVIKDDIWPNPLQYYL 234
>sp|Q9EQU5|SET_MOUSE SET protein (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A)
(Template-activating factor I) (TAF-I)
Length = 289
Score = 94.0 bits (232), Expect = 2e-19
Identities = 48/114 (42%), Positives = 64/114 (56%), Gaps = 1/114 (0%)
Frame = +2
Query: 11 LDVEEFDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEGKNFVKS 187
++V EF+DIKSG++I F N YF N ++K H+ ES + + + WK GK+ K
Sbjct: 122 VEVTEFEDIKSGYRIDFYFDENPYFENKVLSKEFHLNESGDPSSKSTEIKWKSGKDLTKR 181
Query: 188 LNESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 349
+++ N P SF WFT ELGEVIKDD+WPNPLQYYL
Sbjct: 182 SSQTQNKASRKRQHEE--PESFFTWFTDHSDAGADELGEVIKDDIWPNPLQYYL 233
>sp|Q63945|SET_RAT SET protein (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A)
(Template-activating factor I) (TAF-I) (Liver
regeneration-related protein LRRGR00002)
Length = 289
Score = 94.0 bits (232), Expect = 2e-19
Identities = 48/114 (42%), Positives = 64/114 (56%), Gaps = 1/114 (0%)
Frame = +2
Query: 11 LDVEEFDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEGKNFVKS 187
++V EF+DIKSG++I F N YF N ++K H+ ES + + + WK GK+ K
Sbjct: 122 VEVTEFEDIKSGYRIDFYFDENPYFENKVLSKEFHLNESGDPSSKSTEIKWKSGKDLTKR 181
Query: 188 LNESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 349
+++ N P SF WFT ELGEVIKDD+WPNPLQYYL
Sbjct: 182 SSQTQNKASRKRQHEE--PESFFTWFTDHSDAGADELGEVIKDDIWPNPLQYYL 233
>sp|P53997|SET_DROME SET protein
Length = 269
Score = 92.4 bits (228), Expect = 7e-19
Identities = 49/120 (40%), Positives = 64/120 (53%), Gaps = 7/120 (5%)
Frame = +2
Query: 11 LDVEEFDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGESEIK-------TTCDPVDWKEG 169
L+VEEF+DIKSG++I F N YF N +TK H+ + +T P+ WKEG
Sbjct: 111 LEVEEFEDIKSGYRINFHFDENPYFENKVLTKEFHLNSAAASENGDWPASTSTPIKWKEG 170
Query: 170 KNFVKSLNESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 349
KN +K L L +F WF+ + E+ E+IKDDLWPNPLQYYL
Sbjct: 171 KNLLKLL---LTKPYGNKKKRNSEYKTFFDWFSDNTDPVNDEIAELIKDDLWPNPLQYYL 227
>sp|Q18240|SPR2_CAEEL Suppressor of presenilin 2
Length = 312
Score = 91.3 bits (225), Expect = 2e-18
Identities = 47/113 (41%), Positives = 61/113 (53%)
Frame = +2
Query: 11 LDVEEFDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGESEIKTTCDPVDWKEGKNFVKSL 190
L+V+EF+D++SGFKIIMTF PNEYF N ITKS H+ T ++WKE K
Sbjct: 109 LEVQEFEDLRSGFKIIMTFDPNEYFTNEVITKSYHLQSESPSTEITEIEWKENKK----- 163
Query: 191 NESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 349
+F++W T E+ EVIKDDL+ NPLQYY+
Sbjct: 164 --------PPFPEDGDSAHTFLEWLTYAALPDSDEIAEVIKDDLYVNPLQYYV 208
>sp|O88852|TSYL1_MOUSE Testis-specific Y-encoded-like protein 1 (TSPY-like 1)
Length = 379
Score = 62.0 bits (149), Expect = 1e-09
Identities = 37/117 (31%), Positives = 54/117 (46%), Gaps = 4/117 (3%)
Frame = +2
Query: 11 LDVEEFDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEG---KNF 178
L+V+E K+G K F N YF N I K V S + + P+ W+ G ++F
Sbjct: 249 LEVKELRHPKTGCKFKFFFRRNPYFRNKLIVKEYEVRSSGRVVSLSTPIIWRRGHEPQSF 308
Query: 179 VKSLNESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 349
++ + + SF WF+ + E+IK+DLWPNPLQYYL
Sbjct: 309 IRRNQDLI--------------CSFFTWFSDHSLPESDRIAEIIKEDLWPNPLQYYL 351
>sp|Q9H0U9|TSYL1_HUMAN Testis-specific Y-encoded-like protein 1 (TSPY-like 1)
Length = 438
Score = 61.2 bits (147), Expect = 2e-09
Identities = 36/117 (30%), Positives = 55/117 (47%), Gaps = 4/117 (3%)
Frame = +2
Query: 11 LDVEEFDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEG---KNF 178
L+V+E ++G K F N YF N I K V S + + P+ W+ G ++F
Sbjct: 308 LEVKELRHPRTGCKFKFFFRRNPYFRNKLIVKEYEVRSSGRVVSLSTPIIWRRGHEPQSF 367
Query: 179 VKSLNESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 349
++ + + SF WF+ ++ E+IK+DLWPNPLQYYL
Sbjct: 368 IRRNQDLI--------------CSFFTWFSDHSLPESDKIAEIIKEDLWPNPLQYYL 410
>sp|P13825|ASP_PLAFS Aspartic acid-rich protein precursor
Length = 253
Score = 57.8 bits (138), Expect = 2e-08
Identities = 32/118 (27%), Positives = 56/118 (47%), Gaps = 3/118 (2%)
Frame = +2
Query: 11 LDVEEFDDIKSGFKIIMTFSPN--EYFNNTTITKSIHVGESEIKTT-CDPVDWKEGKNFV 181
LD+++ D +KI F E+ T+ K + ++ K C + WKEGKN +
Sbjct: 91 LDLKDNMDNNGSYKITFIFGEKAKEFMEPLTLVKHVTFDNNQEKVVECTRIKWKEGKNPI 150
Query: 182 KSLNESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYLAV 355
++ + + S +WFT+D ++GE+I+ ++W NPL YYL +
Sbjct: 151 AAVTHNRSDLDNEIPKW-----SIFEWFTTDELQDKPDVGELIRREIWHNPLSYYLGL 203
>sp|Q9UJ04|TSYL4_HUMAN Testis-specific Y-encoded-like protein 4 (TSPY-like 4)
Length = 414
Score = 56.6 bits (135), Expect = 4e-08
Identities = 33/114 (28%), Positives = 49/114 (42%), Gaps = 1/114 (0%)
Frame = +2
Query: 11 LDVEEFDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEGKNFVKS 187
L+VEE ++G K F N YF N + K S + + P+ W G++
Sbjct: 282 LEVEELKHPRAGCKFKFIFQGNPYFRNEGLVKEYERRSSGRVVSLSTPIRWHRGQDPQAH 341
Query: 188 LNESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 349
++ + SF WF+ + E+IK +LWPNPLQYYL
Sbjct: 342 IHRNREGNTIP---------SFFNWFSDHSLLEFDRIAEIIKGELWPNPLQYYL 386
>sp|Q9H489|TSY3_HUMAN Testis-specific Y-encoded-like protein 3 (TSPY-like 3)
Length = 355
Score = 53.5 bits (127), Expect = 3e-07
Identities = 33/114 (28%), Positives = 48/114 (42%), Gaps = 1/114 (0%)
Frame = +2
Query: 11 LDVEEFDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEGKNFVKS 187
L+V E ++G K F N YF N I K S + + + W G+
Sbjct: 224 LEVRELRHSRTGCKFKFRFWSNPYFQNKVIVKEYECRASGRVVSIATRIRWHWGQEPPAL 283
Query: 188 LNESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 349
++ + + SF WF+ + ++IKDDLWPNPLQYYL
Sbjct: 284 VHRNRDTVR-----------SFFSWFSQHSLPEADRVAQIIKDDLWPNPLQYYL 326
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,898,237
Number of Sequences: 369166
Number of extensions: 863250
Number of successful extensions: 2026
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1982
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2006
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4078830820
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)