Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_A10
(904 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9BYG5|PAR6B_HUMAN Partitioning defective 6 homolog beta... 228 2e-59
sp|Q9JK83|PAR6B_MOUSE Partitioning defective 6 homolog beta... 227 3e-59
sp|Q9JK84|PAR6G_MOUSE Partitioning defective 6 homolog gamm... 219 8e-57
sp|Q9BYG4|PAR6G_HUMAN Partitioning defective 6 homolog gamm... 214 2e-55
sp|Q9NAN2|PAR6_CAEEL Partitioning defective 6 protein 206 6e-53
sp|Q9NPB6|PAR6A_HUMAN Partitioning defective 6 homolog alph... 202 8e-52
sp|Q9Z101|PAR6A_MOUSE Partitioning defective 6 homolog alph... 200 5e-51
sp|Q6B4M5|PAR6A_RAT Partitioning defective 6 homolog alpha ... 200 5e-51
sp|Q5RDQ2|MPP5_PONPY MAGUK p55 subfamily member 5 56 2e-07
sp|Q9JLB2|MPP5_MOUSE MAGUK p55 subfamily member 5 (Protein ... 55 3e-07
>sp|Q9BYG5|PAR6B_HUMAN Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B)
Length = 372
Score = 228 bits (580), Expect = 2e-59
Identities = 122/235 (51%), Positives = 160/235 (68%), Gaps = 1/235 (0%)
Frame = +1
Query: 1 ELKSKFDAEFRRFRINLAIHSSFEDFKVLLSNIHKLSNIDFVIQYIDENESSLLPINNDD 180
E+KSKF AEFRRF + + FE+F LL ++HK+ N+D ++ Y D + LLPINNDD
Sbjct: 18 EVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLVGYADIH-GDLLPINNDD 76
Query: 181 NYNRALSLKMRPLRIIIQRKGESYGELHGYGPIVRSKVPVSKIISAMNEKRSNHSNISIL 360
NY++A+S LRI IQ+K E+ G +++ K ++ ++ N ++ H IS+
Sbjct: 77 NYHKAVSTANPLLRIFIQKKEEADYSAFGTDTLIKKKNVLTNVLRPDNHRKKPHIVISMP 136
Query: 361 DDFXXXXXXXXXXXXPVAYRRVKLMR-NSSKPLGFYIRDGVSVRATPNGIEKVQAIFISR 537
DF P +RRV+L + + KPLGFYIRDG SVR TP+G+EKV IFISR
Sbjct: 137 QDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISR 196
Query: 538 LIAKGLAESTGLLAVNDEVIEVNGIEVRGKTLDQVTDMMVANSSNLIITVKPVNQ 702
L+ GLA+STGLLAVNDEV+EVNGIEV GK+LDQVTDMM+ANS NLIITV+P NQ
Sbjct: 197 LVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQ 251
>sp|Q9JK83|PAR6B_MOUSE Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B)
Length = 371
Score = 227 bits (579), Expect = 3e-59
Identities = 123/235 (52%), Positives = 159/235 (67%), Gaps = 1/235 (0%)
Frame = +1
Query: 1 ELKSKFDAEFRRFRINLAIHSSFEDFKVLLSNIHKLSNIDFVIQYIDENESSLLPINNDD 180
E+KSKF AEFRRF + + FE+F LL ++HK+ N+D ++ Y D + L PINNDD
Sbjct: 18 EVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLVGYADIH-GDLPPINNDD 76
Query: 181 NYNRALSLKMRPLRIIIQRKGESYGELHGYGPIVRSKVPVSKIISAMNEKRSNHSNISIL 360
NY++A+S LRI IQ+K E+ G ++R K +S ++ N ++ H IS+
Sbjct: 77 NYHKAVSTANPLLRIFIQKKEEADYSAFGTDTLIRKKNMLSNVLRPDNHRKKPHIVISMP 136
Query: 361 DDFXXXXXXXXXXXXPVAYRRVKLMR-NSSKPLGFYIRDGVSVRATPNGIEKVQAIFISR 537
DF P +RRV+L + + KPLGFYIRDG SVR TP+G+EKV IFISR
Sbjct: 137 QDFRPVSSIIDVDILPETHRRVRLCKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISR 196
Query: 538 LIAKGLAESTGLLAVNDEVIEVNGIEVRGKTLDQVTDMMVANSSNLIITVKPVNQ 702
L+ GLA+STGLLAVNDEV+EVNGIEV GK+LDQVTDMM+ANS NLIITV+P NQ
Sbjct: 197 LVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQ 251
>sp|Q9JK84|PAR6G_MOUSE Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A)
Length = 382
Score = 219 bits (558), Expect = 8e-57
Identities = 125/238 (52%), Positives = 157/238 (65%), Gaps = 4/238 (1%)
Frame = +1
Query: 1 ELKSKFDAEFRRFRINLAIHSSFEDFKVLLSNIHKLSNIDFVIQYIDENESSLLPINNDD 180
E+KSKF AEFRRF ++ FEDF L+ + H +SN + I Y D + LLPINNDD
Sbjct: 20 EVKSKFGAEFRRFSLDRHKPGKFEDFYQLVVHTHHISNTEVTIGYADVH-GDLLPINNDD 78
Query: 181 NYNRALSLKMRPLRIIIQRKGESYGELHGYGPIVRSKVPVSKIISAMNE---KRSNHSNI 351
N+ +A+S LR+ IQ++ E+ G G + R K K++ + + +R H NI
Sbjct: 79 NFCKAVSSANPLLRVFIQKREEADHYSFGAGTLSRKK----KVLVTLRDDGLRRRPHLNI 134
Query: 352 SILDDFXXXXXXXXXXXXPVAYRRVKLMRNS-SKPLGFYIRDGVSVRATPNGIEKVQAIF 528
S+ DF P +RRV+L R+ KPLGFYIRDG SVR TP+G+EKV IF
Sbjct: 135 SMPHDFRPVSSIIDVDILPETHRRVRLYRHGYEKPLGFYIRDGTSVRVTPHGLEKVPGIF 194
Query: 529 ISRLIAKGLAESTGLLAVNDEVIEVNGIEVRGKTLDQVTDMMVANSSNLIITVKPVNQ 702
ISR++ GLAESTGLLAVNDEV+EVNGIEV GKTLDQVTDMM+ANS NLI+TVKP NQ
Sbjct: 195 ISRMVPGGLAESTGLLAVNDEVLEVNGIEVAGKTLDQVTDMMIANSHNLIVTVKPANQ 252
>sp|Q9BYG4|PAR6G_HUMAN Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D)
Length = 376
Score = 214 bits (546), Expect = 2e-55
Identities = 123/238 (51%), Positives = 156/238 (65%), Gaps = 4/238 (1%)
Frame = +1
Query: 1 ELKSKFDAEFRRFRINLAIHSSFEDFKVLLSNIHKLSNIDFVIQYIDENESSLLPINNDD 180
E+KSKF AEFRRF ++ FEDF L+ + H +SN D I Y D + LLPINNDD
Sbjct: 20 EVKSKFGAEFRRFSLDRHKPGKFEDFYKLVVHTHHISNSDVTIGYADVH-GDLLPINNDD 78
Query: 181 NYNRALSLKMRPLRIIIQRKGESYGELHGYGPIVRSKVPVSKIISAMNE---KRSNHSNI 351
N+ +A+S LR+ IQ++ E+ G G + R + + + A+ + +R H +I
Sbjct: 79 NFCKAVSSANPLLRVFIQKREEAERGSLGAGSLCRRR----RALGALRDEGPRRRAHLDI 134
Query: 352 SILDDFXXXXXXXXXXXXPVAYRRVKLMRNS-SKPLGFYIRDGVSVRATPNGIEKVQAIF 528
+ DF P +RRV+L R+ KPLGFYIRDG SVR TP+G+EKV IF
Sbjct: 135 GLPRDFRPVSSIIDVDLVPETHRRVRLHRHGCEKPLGFYIRDGASVRVTPHGLEKVPGIF 194
Query: 529 ISRLIAKGLAESTGLLAVNDEVIEVNGIEVRGKTLDQVTDMMVANSSNLIITVKPVNQ 702
ISR++ GLAESTGLLAVNDEV+EVNGIEV GKTLDQVTDMM+ANS NLI+TVKP NQ
Sbjct: 195 ISRMVPGGLAESTGLLAVNDEVLEVNGIEVAGKTLDQVTDMMIANSHNLIVTVKPANQ 252
>sp|Q9NAN2|PAR6_CAEEL Partitioning defective 6 protein
Length = 309
Score = 206 bits (525), Expect = 6e-53
Identities = 120/243 (49%), Positives = 158/243 (65%), Gaps = 4/243 (1%)
Frame = +1
Query: 1 ELKSKFDAEFRRFRINLAIHS--SFEDFKVLLSNIHKLSNIDFVIQYIDENESSLLPINN 174
++KSKFD+E+RRF I + S S++ F+ L+ +H L ++ F + Y + LLPI N
Sbjct: 16 QVKSKFDSEWRRFSIPMHSASGVSYDGFRSLVEKLHHLESVQFTLCY-NSTGGDLLPITN 74
Query: 175 DDNYNRALSLKMRPLRIIIQRKGESYGELHGYGPIVRSKVP-VSKIISAMNEKRSNHSNI 351
DDN ++ LR++IQR+GES+ E +GYG + +S +++ KRS +I
Sbjct: 75 DDNLRKSFESARPLLRLLIQRRGESWEEKYGYGTDSDKRWKGISSLMAQKPPKRSY--SI 132
Query: 352 SILDDFXXXXXXXXXXXXPVAYRRVKLMRNSS-KPLGFYIRDGVSVRATPNGIEKVQAIF 528
S +DF P A+RRV+L ++ +PLGFYIRDG SVR T G+ KV IF
Sbjct: 133 SNPEDFRQVSAIIDVDIVPEAHRRVRLCKHGQERPLGFYIRDGTSVRVTERGVVKVSGIF 192
Query: 529 ISRLIAKGLAESTGLLAVNDEVIEVNGIEVRGKTLDQVTDMMVANSSNLIITVKPVNQNT 708
ISRL+ GLAESTGLL VNDEV+EVNGIEV GKTLDQVTDMMVAN+ NLIITVKP NQ
Sbjct: 193 ISRLVDGGLAESTGLLGVNDEVLEVNGIEVLGKTLDQVTDMMVANAHNLIITVKPANQRN 252
Query: 709 CLA 717
L+
Sbjct: 253 TLS 255
>sp|Q9NPB6|PAR6A_HUMAN Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A)
(PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40)
Length = 346
Score = 202 bits (515), Expect = 8e-52
Identities = 113/236 (47%), Positives = 154/236 (65%), Gaps = 2/236 (0%)
Frame = +1
Query: 1 ELKSKFDAEFRRFRINLAIHSSFEDFKVLLSNIHKLSNIDFVIQYIDENESSLLPINNDD 180
E+KSKFDAEFRRF + A S F++F LL +H++ +D ++ Y D + LLP+ NDD
Sbjct: 17 EVKSKFDAEFRRFALPRASVSGFQEFSRLLRAVHQIPGLDVLLGYTDAH-GDLLPLTNDD 75
Query: 181 NYNRALSLKMRPLRIIIQRKGESYGELHGYGPIVRSKVPVSKIISAMNEKRSNHSN-ISI 357
+ +RAL+ PLR+++Q++ E+ + + ++ + R+ IS+
Sbjct: 76 SLHRALASGPPPLRLLVQKRAEADSSGLAFASNSLQRRKKGLLLRPVAPLRTRPPLLISL 135
Query: 358 LDDFXXXXXXXXXXXXPVAYRRVKLMRNSS-KPLGFYIRDGVSVRATPNGIEKVQAIFIS 534
DF P +RRV+L ++ S +PLGFYIRDG+SVR P G+E+V IFIS
Sbjct: 136 PQDFRQVSSVIDVDLLPETHRRVRLHKHGSDRPLGFYIRDGMSVRVAPQGLERVPGIFIS 195
Query: 535 RLIAKGLAESTGLLAVNDEVIEVNGIEVRGKTLDQVTDMMVANSSNLIITVKPVNQ 702
RL+ GLAESTGLLAV+DE++EVNGIEV GKTLDQVTDMMVANS NLI+TVKP NQ
Sbjct: 196 RLVRGGLAESTGLLAVSDEILEVNGIEVAGKTLDQVTDMMVANSHNLIVTVKPANQ 251
>sp|Q9Z101|PAR6A_MOUSE Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A)
(PAR-6)
Length = 346
Score = 200 bits (508), Expect = 5e-51
Identities = 115/238 (48%), Positives = 156/238 (65%), Gaps = 4/238 (1%)
Frame = +1
Query: 1 ELKSKFDAEFRRFRINLAIHSSFEDFKVLLSNIHKLSNIDFVIQYIDENESSLLPINNDD 180
E+KSKFDAEFRRF + F++F LL +H++ +D ++ Y D + LLP+ NDD
Sbjct: 17 EVKSKFDAEFRRFALPRTSVRGFQEFSRLLCVVHQIPGLDVLLGYTDAH-GDLLPLTNDD 75
Query: 181 NYNRALSLKMRPLRIIIQRK--GESYGELHGYGPIVRSKVPVSKIISAMNEKRSNHSN-I 351
+ +RAL+ PLR+++Q++ G+S G + R K + ++ + R+ I
Sbjct: 76 SLHRALASGPPPLRLLVQKRAEGDSSGLAFASNSLQRRKKGL--LLRPVAPLRTRPPLLI 133
Query: 352 SILDDFXXXXXXXXXXXXPVAYRRVKLMRNSS-KPLGFYIRDGVSVRATPNGIEKVQAIF 528
S+ DF P +RRV+L ++ S +PLGFYIRDG+SVR P G+E+V IF
Sbjct: 134 SLPQDFRQVSSVIDVDLLPETHRRVRLHKHGSDRPLGFYIRDGMSVRVAPQGLERVPGIF 193
Query: 529 ISRLIAKGLAESTGLLAVNDEVIEVNGIEVRGKTLDQVTDMMVANSSNLIITVKPVNQ 702
ISRL+ GLAESTGLLAV+DE++EVNGIEV GKTLDQVTDMMVANS NLI+TVKP NQ
Sbjct: 194 ISRLVRGGLAESTGLLAVSDEILEVNGIEVAGKTLDQVTDMMVANSHNLIVTVKPANQ 251
>sp|Q6B4M5|PAR6A_RAT Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A)
(PAR-6)
Length = 346
Score = 200 bits (508), Expect = 5e-51
Identities = 115/238 (48%), Positives = 156/238 (65%), Gaps = 4/238 (1%)
Frame = +1
Query: 1 ELKSKFDAEFRRFRINLAIHSSFEDFKVLLSNIHKLSNIDFVIQYIDENESSLLPINNDD 180
E+KSKFDAEFRRF + F++F LL +H++ +D ++ Y D + LLP+ NDD
Sbjct: 17 EVKSKFDAEFRRFALPRTSVRGFQEFSRLLCVVHQIPGLDVLLGYTDAH-GDLLPLTNDD 75
Query: 181 NYNRALSLKMRPLRIIIQRK--GESYGELHGYGPIVRSKVPVSKIISAMNEKRSNHSN-I 351
+ +RAL+ PLR+++Q++ G+S G + R K + ++ + R+ I
Sbjct: 76 SLHRALASGPPPLRLLVQKRAEGDSSGLAFASNSLQRRKKGL--LLRPVAPLRTRPPLLI 133
Query: 352 SILDDFXXXXXXXXXXXXPVAYRRVKLMRNSS-KPLGFYIRDGVSVRATPNGIEKVQAIF 528
S+ DF P +RRV+L ++ S +PLGFYIRDG+SVR P G+E+V IF
Sbjct: 134 SLPQDFRQVSSVIDVDLLPETHRRVRLHKHGSDRPLGFYIRDGMSVRVAPQGLERVPGIF 193
Query: 529 ISRLIAKGLAESTGLLAVNDEVIEVNGIEVRGKTLDQVTDMMVANSSNLIITVKPVNQ 702
ISRL+ GLAESTGLLAV+DE++EVNGIEV GKTLDQVTDMMVANS NLI+TVKP NQ
Sbjct: 194 ISRLVRGGLAESTGLLAVSDEILEVNGIEVAGKTLDQVTDMMVANSHNLIVTVKPANQ 251
>sp|Q5RDQ2|MPP5_PONPY MAGUK p55 subfamily member 5
Length = 675
Score = 55.8 bits (133), Expect = 2e-07
Identities = 30/93 (32%), Positives = 51/93 (54%)
Frame = +1
Query: 424 VKLMRNSSKPLGFYIRDGVSVRATPNGIEKVQAIFISRLIAKGLAESTGLLAVNDEVIEV 603
V++ + PLG +R+ ++ ++ ISR++ G AE +GLL DEV+E+
Sbjct: 257 VRIEKARDIPLGATVRN------------EMDSVIISRIVKGGAAEKSGLLHEGDEVLEI 304
Query: 604 NGIEVRGKTLDQVTDMMVANSSNLIITVKPVNQ 702
NGIE+RGK +++V D++ L + P Q
Sbjct: 305 NGIEIRGKDVNEVFDLLADMHGTLTFVLIPSQQ 337
>sp|Q9JLB2|MPP5_MOUSE MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1)
Length = 675
Score = 55.1 bits (131), Expect = 3e-07
Identities = 30/93 (32%), Positives = 51/93 (54%)
Frame = +1
Query: 424 VKLMRNSSKPLGFYIRDGVSVRATPNGIEKVQAIFISRLIAKGLAESTGLLAVNDEVIEV 603
V++ + PLG +R+ ++ ++ ISR++ G AE +GLL DEV+E+
Sbjct: 257 VRIEKARDIPLGATVRN------------EMDSVIISRIVKGGAAEKSGLLHEGDEVLEI 304
Query: 604 NGIEVRGKTLDQVTDMMVANSSNLIITVKPVNQ 702
NGIE+RGK +++V D++ L + P Q
Sbjct: 305 NGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.135 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,366,002
Number of Sequences: 369166
Number of extensions: 1456223
Number of successful extensions: 3497
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3294
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3473
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9126484700
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)