Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_A01
(916 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O43772|MCAT_HUMAN Mitochondrial carnitine/acylcarnitine ... 352 6e-97
sp|Q8HXY2|MCAT_MACFA Mitochondrial carnitine/acylcarnitine ... 350 3e-96
sp|Q9Z2Z6|MCAT_MOUSE Mitochondrial carnitine/acylcarnitine ... 345 8e-95
sp|P97521|MCAT_RAT Mitochondrial carnitine/acylcarnitine ca... 345 8e-95
sp|Q9VQG4|COLT_DROME Congested-like trachea protein 307 2e-83
sp|Q27257|DIF1_CAEEL Protein dif-1 301 2e-81
sp|Q93XM7|MCAT_ARATH Mitochondrial carnitine/acylcarnitine ... 182 9e-46
sp|Q12289|CRC1_YEAST Mitochondrial carnitine carrier 155 1e-37
sp|Q9WVD5|ORNT1_MOUSE Mitochondrial ornithine transporter 1... 153 7e-37
sp|Q9Y619|ORNT1_HUMAN Mitochondrial ornithine transporter 1... 151 2e-36
>sp|O43772|MCAT_HUMAN Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 352 bits (904), Expect = 6e-97
Identities = 172/264 (65%), Positives = 202/264 (76%)
Frame = +1
Query: 1 TLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVCFFG 180
T+KVRLQ P PG+PP+Y G DCF +TL EG G Y+GMAAP+IGVTPMFAVCFFG
Sbjct: 33 TVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLYRGMAAPIIGVTPMFAVCFFG 92
Query: 181 YNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKG 360
+ LG+KLQ K L+ PQ+FAAGMLSGVFTT IMTPGERIKCLLQ+Q +S E KY G
Sbjct: 93 FGLGKKLQQKHPEDVLSYPQLFAAGMLSGVFTTGIMTPGERIKCLLQIQASSGES-KYTG 151
Query: 361 PGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGR 540
D +KLY+E GIR IYKGT TL+RD+PA+G YFM+YEWLK I TPEG S LS R
Sbjct: 152 TLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEWLKNIFTPEGKRVSELSAPR 211
Query: 541 TLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSP 720
L AGGIAG+ NW V IPPD LKSR QTAP GKYP+G R V RE++ +EG+ LY+G +
Sbjct: 212 ILVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKGFNA 271
Query: 721 VLIRAFPANAACFLGYEVSLKLLN 792
V+IRAFPANAACFLG+EV++K LN
Sbjct: 272 VMIRAFPANAACFLGFEVAMKFLN 295
Score = 66.6 bits (161), Expect = 9e-11
Identities = 40/95 (42%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
Frame = +1
Query: 526 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE---GKYP--HGLRSVFREMMANEG 690
+SP + L AGG G+C V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREG 67
Query: 691 IVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNK 795
I GLYRG++ +I P A CF G+ + KL K
Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQK 102
>sp|Q8HXY2|MCAT_MACFA Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 350 bits (898), Expect = 3e-96
Identities = 170/264 (64%), Positives = 202/264 (76%)
Frame = +1
Query: 1 TLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVCFFG 180
T+KVRLQ P PG+PP+Y G DCF +TL EG G Y+GMAAP+IGVTPMFAVCFFG
Sbjct: 33 TVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGIRGLYRGMAAPIIGVTPMFAVCFFG 92
Query: 181 YNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKG 360
+ LG+KLQ K L+ PQ+FAAGMLSG+FTT IMTPGERIKCLLQ+Q +S E KY G
Sbjct: 93 FGLGKKLQQKHPEDVLSYPQLFAAGMLSGIFTTGIMTPGERIKCLLQIQASSGET-KYTG 151
Query: 361 PGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGR 540
D +KLY+E GIR IYKGT TL+RD+PA+G YFM+YEW+K I TPEG S LS R
Sbjct: 152 TLDCAKKLYQEFGIRGIYKGTVVTLMRDVPASGMYFMTYEWVKNIFTPEGKRVSELSVPR 211
Query: 541 TLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSP 720
L AGGIAG+ NW V IPPD LKSR QTAP GKYP+G R V RE++ +EG+ LY+G +
Sbjct: 212 VLVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIPDEGVTSLYKGFNA 271
Query: 721 VLIRAFPANAACFLGYEVSLKLLN 792
V+IRAFPANAACFLG+EV++K LN
Sbjct: 272 VMIRAFPANAACFLGFEVAMKFLN 295
Score = 65.5 bits (158), Expect = 2e-10
Identities = 40/95 (42%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
Frame = +1
Query: 526 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE---GKYP--HGLRSVFREMMANEG 690
+SP + L AGG G+C V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREG 67
Query: 691 IVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNK 795
I GLYRG++ +I P A CF G+ + KL K
Sbjct: 68 IRGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQK 102
>sp|Q9Z2Z6|MCAT_MOUSE Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC) (mCAC)
Length = 301
Score = 345 bits (886), Expect = 8e-95
Identities = 166/264 (62%), Positives = 198/264 (75%)
Frame = +1
Query: 1 TLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVCFFG 180
T+KVRLQ P G+PP+Y G +DCF +TL EG G Y+GMAAP+IGVTPMFAVCFFG
Sbjct: 33 TVKVRLQTQPPSLSGQPPMYSGTLDCFRKTLMREGITGLYRGMAAPIIGVTPMFAVCFFG 92
Query: 181 YNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKG 360
+ LG+KLQ K L+ PQ+F AGMLSGVFTT IMTPGERIKCLLQ+Q +S E KY G
Sbjct: 93 FGLGKKLQQKSPEDELSYPQLFTAGMLSGVFTTGIMTPGERIKCLLQIQASSGEN-KYSG 151
Query: 361 PGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGR 540
D +KLY+E GIR YKGT TL+RD+PA+G YFM+YEWLK + TPEG S LS R
Sbjct: 152 TLDCAKKLYQEFGIRGFYKGTVLTLMRDVPASGMYFMTYEWLKNLFTPEGKSVSDLSVPR 211
Query: 541 TLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSP 720
L AGG AG+ NW V IPPD LKSR QTAP GKYP+G R V RE++ EG+ LY+G +
Sbjct: 212 ILVAGGFAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIREEGVTSLYKGFNA 271
Query: 721 VLIRAFPANAACFLGYEVSLKLLN 792
V+IRAFPANAACFLG+E+++K LN
Sbjct: 272 VMIRAFPANAACFLGFEIAMKFLN 295
Score = 69.7 bits (169), Expect = 1e-11
Identities = 41/95 (43%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
Frame = +1
Query: 526 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAP---EGKYP--HGLRSVFREMMANEG 690
+SP + L AGG GMC V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPFKNLLAGGFGGMCLVFVGHPLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRKTLMREG 67
Query: 691 IVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNK 795
I GLYRG++ +I P A CF G+ + KL K
Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQK 102
>sp|P97521|MCAT_RAT Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 345 bits (886), Expect = 8e-95
Identities = 165/264 (62%), Positives = 198/264 (75%)
Frame = +1
Query: 1 TLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVCFFG 180
T+KVRLQ P PG+PP+Y G +DCF +TL EG G Y+GMAAP+IGVTPMFAVCFFG
Sbjct: 33 TVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLFREGITGLYRGMAAPIIGVTPMFAVCFFG 92
Query: 181 YNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKG 360
+ LG++LQ K LT PQ+F AGMLSGVFTT IMTPGERIKCLLQ+Q AS KY G
Sbjct: 93 FGLGKRLQQKSPEDELTYPQLFTAGMLSGVFTTGIMTPGERIKCLLQIQ-ASSGKNKYSG 151
Query: 361 PGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGR 540
D +KLY+E GIR YKGTA TL+RD+PA+G YFM+YEWLK + TP+G LS R
Sbjct: 152 TLDCAKKLYQEFGIRGFYKGTALTLMRDVPASGMYFMTYEWLKNLFTPQGKSVHDLSVPR 211
Query: 541 TLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSP 720
L AGG G+ NW+V IPPD LKSR QTAP GKYP+G R V RE++ EG+ LY+G +
Sbjct: 212 VLVAGGFRGIFNWVVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIREEGVTSLYKGFNA 271
Query: 721 VLIRAFPANAACFLGYEVSLKLLN 792
V+IRAFPANAACFLG+E+ +K+LN
Sbjct: 272 VMIRAFPANAACFLGFEIPMKILN 295
Score = 65.5 bits (158), Expect = 2e-10
Identities = 39/95 (41%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
Frame = +1
Query: 526 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE---GKYP--HGLRSVFREMMANEG 690
+SP + L AGG G+C V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLFREG 67
Query: 691 IVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNK 795
I GLYRG++ +I P A CF G+ + +L K
Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGFGLGKRLQQK 102
>sp|Q9VQG4|COLT_DROME Congested-like trachea protein
Length = 306
Score = 307 bits (787), Expect = 2e-83
Identities = 146/266 (54%), Positives = 193/266 (72%)
Frame = +1
Query: 1 TLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVCFFG 180
T+KVRLQ MP P PGE P+Y+G DC +T++NEG G YKGM+APL GV P+FA+CF G
Sbjct: 38 TIKVRLQTMPRPAPGEQPLYRGTFDCAAKTIKNEGVRGLYKGMSAPLTGVAPIFAMCFAG 97
Query: 181 YNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKG 360
Y LG++LQ + E+ LT PQIF AG SG+F+T IM PGERIK LLQ Q KY G
Sbjct: 98 YALGKRLQQRGEDAKLTYPQIFVAGSFSGLFSTLIMAPGERIKVLLQTQQGQGGERKYNG 157
Query: 361 PGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGR 540
D KLYKEGG+RS++KG+ AT+LRD+PA G YF+ YE L+++ + + +S
Sbjct: 158 MIDCAGKLYKEGGLRSVFKGSCATMLRDLPANGLYFLVYEALQDVAKSK-SETGQISTAS 216
Query: 541 TLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSP 720
T+FAGG+AGM W++ +P D LKSRLQ+APEG Y HG+RSVF++++ +G + LYRGV+P
Sbjct: 217 TIFAGGVAGMAYWILGMPADVLKSRLQSAPEGTYKHGIRSVFKDLIVKDGPLALYRGVTP 276
Query: 721 VLIRAFPANAACFLGYEVSLKLLNKV 798
+++RAFPANAACF G E++ K N V
Sbjct: 277 IMLRAFPANAACFFGIELANKFFNIV 302
Score = 60.1 bits (144), Expect = 9e-09
Identities = 35/91 (38%), Positives = 48/91 (52%), Gaps = 5/91 (5%)
Frame = +1
Query: 529 SPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE---GKYP--HGLRSVFREMMANEGI 693
+P ++ GG G+CN L P DT+K RLQT P G+ P G + + NEG+
Sbjct: 14 NPVKSFLTGGFGGICNVLSGHPLDTIKVRLQTMPRPAPGEQPLYRGTFDCAAKTIKNEGV 73
Query: 694 VGLYRGVSPVLIRAFPANAACFLGYEVSLKL 786
GLY+G+S L P A CF GY + +L
Sbjct: 74 RGLYKGMSAPLTGVAPIFAMCFAGYALGKRL 104
>sp|Q27257|DIF1_CAEEL Protein dif-1
Length = 312
Score = 301 bits (770), Expect = 2e-81
Identities = 152/262 (58%), Positives = 191/262 (72%), Gaps = 2/262 (0%)
Frame = +1
Query: 1 TLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVCFFG 180
T+KVR+Q MP+PKPGE P + G +DC +T+ EG YKGMAAPL+GV+P+FAV F G
Sbjct: 27 TVKVRIQTMPMPKPGEKPQFTGALDCVKRTVSKEGFFALYKGMAAPLVGVSPLFAVFFGG 86
Query: 181 YNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQ--GASKEPPKY 354
+G+ LQ D + +T Q AG L+GVFTT +M PGERIKCLLQVQ G++ Y
Sbjct: 87 CAVGKWLQQTDPSQEMTFIQNANAGALAGVFTTIVMVPGERIKCLLQVQQAGSAGSGVHY 146
Query: 355 KGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSP 534
GP DV++KLYK+GGI SIY+GT ATLLRDIPA+ Y YE+LK+ + EG ++ LSP
Sbjct: 147 DGPLDVVKKLYKQGGISSIYRGTGATLLRDIPASAAYLSVYEYLKKKFSGEGAQRT-LSP 205
Query: 535 GRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGV 714
G TL AGG+AG+ NW VCIP D LKSRLQTAPEGKYP G+R V RE++ EG L++G
Sbjct: 206 GATLMAGGLAGIANWGVCIPADVLKSRLQTAPEGKYPDGIRGVLREVLREEGPRALFKGF 265
Query: 715 SPVLIRAFPANAACFLGYEVSL 780
PV++RAFPANAACF G E++L
Sbjct: 266 WPVMLRAFPANAACFFGLELTL 287
Score = 44.7 bits (104), Expect = 4e-04
Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 5/80 (6%)
Frame = +1
Query: 550 AGGIAGMCNWLVCIPPDTLKSRLQTAP---EGKYPH--GLRSVFREMMANEGIVGLYRGV 714
AGG+ G C +V P DT+K R+QT P G+ P G + ++ EG LY+G+
Sbjct: 10 AGGVGGSCTVIVGHPFDTVKVRIQTMPMPKPGEKPQFTGALDCVKRTVSKEGFFALYKGM 69
Query: 715 SPVLIRAFPANAACFLGYEV 774
+ L+ P A F G V
Sbjct: 70 AAPLVGVSPLFAVFFGGCAV 89
>sp|Q93XM7|MCAT_ARATH Mitochondrial carnitine/acylcarnitine carrier-like protein (A BOUT
DE SOUFFLE) (Carnitine/acylcarnitine translocase-like
protein) (CAC-like protein)
Length = 300
Score = 182 bits (463), Expect = 9e-46
Identities = 111/271 (40%), Positives = 142/271 (52%), Gaps = 12/271 (4%)
Frame = +1
Query: 1 TLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVCFFG 180
T+KV+LQ+ P P PG+ P Y G +D QT+ +EG G YKGM APL V AV F
Sbjct: 27 TIKVKLQSQPTPAPGQLPRYTGAIDAVKQTVASEGTKGLYKGMGAPLATVAAFNAVLFTV 86
Query: 181 YNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASK------- 339
L + PLT Q F AG +G + + P E IKC LQ QGA
Sbjct: 87 RGQMEGLLRSEAGVPLTISQQFVAGAGAGFAVSFLACPTELIKCRLQAQGALAGASTTSS 146
Query: 340 --EPPKYKGPGDVIRK-LYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEG 510
KY GP DV R L EGG R ++KG T R++P T F +YE K L G
Sbjct: 147 VVAAVKYGGPMDVARHVLRSEGGARGLFKGLFPTFAREVPGNATMFAAYEAFKRFLA-GG 205
Query: 511 GDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPH--GLRSVFREMMAN 684
D S L G + AGG+AG W + P D +KS LQ + K P G FR+++ +
Sbjct: 206 SDTSSLGQGSLIMAGGVAGASFWGIVYPTDVVKSVLQ-VDDYKNPRYTGSMDAFRKILKS 264
Query: 685 EGIVGLYRGVSPVLIRAFPANAACFLGYEVS 777
EG+ GLY+G P + R+ PANAACFL YE++
Sbjct: 265 EGVKGLYKGFGPAMARSVPANAACFLAYEMT 295
Score = 67.0 bits (162), Expect = 7e-11
Identities = 43/149 (28%), Positives = 68/149 (45%), Gaps = 2/149 (1%)
Frame = +1
Query: 58 YKGLVDCFLQTLRNEGPV-GFYKGMAAPLIGVTPMFAVCFFGYNLGRKLQVKDENTP-LT 231
Y G +D LR+EG G +KG+ P A F Y ++ +T L
Sbjct: 153 YGGPMDVARHVLRSEGGARGLFKGLFPTFAREVPGNATMFAAYEAFKRFLAGGSDTSSLG 212
Query: 232 KPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSI 411
+ + AG ++G I+ P + +K +LQV P+Y G D RK+ K G++ +
Sbjct: 213 QGSLIMAGGVAGASFWGIVYPTDVVKSVLQVDDYKN--PRYTGSMDAFRKILKSEGVKGL 270
Query: 412 YKGTAATLLRDIPATGTYFMSYEWLKEIL 498
YKG + R +PA F++YE + L
Sbjct: 271 YKGFGPAMARSVPANAACFLAYEMTRSSL 299
Score = 58.2 bits (139), Expect = 3e-08
Identities = 53/197 (26%), Positives = 79/197 (40%), Gaps = 16/197 (8%)
Frame = +1
Query: 247 AAGMLSGVFTTAIMTPGERIKCLLQVQG--ASKEPPKYKGPGDVIRKLYKEGGIRSIYKG 420
A+G + G + P + IK LQ Q A + P+Y G D +++ G + +YKG
Sbjct: 9 ASGTVGGAAQLVVGHPFDTIKVKLQSQPTPAPGQLPRYTGAIDAVKQTVASEGTKGLYKG 68
Query: 421 TAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPD 600
A L F ++ +L E G +S + AG AG + P +
Sbjct: 69 MGAPLATVAAFNAVLFTVRGQMEGLLRSEAGVPLTIS--QQFVAGAGAGFAVSFLACPTE 126
Query: 601 TLKSRLQT-------------APEGKYPHGLRSVFREMMANEGIV-GLYRGVSPVLIRAF 738
+K RLQ KY G V R ++ +EG GL++G+ P R
Sbjct: 127 LIKCRLQAQGALAGASTTSSVVAAVKYG-GPMDVARHVLRSEGGARGLFKGLFPTFAREV 185
Query: 739 PANAACFLGYEVSLKLL 789
P NA F YE + L
Sbjct: 186 PGNATMFAAYEAFKRFL 202
Score = 40.0 bits (92), Expect = 0.009
Identities = 18/48 (37%), Positives = 24/48 (50%)
Frame = +1
Query: 52 PVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVCFFGYNLGR 195
P Y G +D F + L++EG G YKG + P A CF Y + R
Sbjct: 249 PRYTGSMDAFRKILKSEGVKGLYKGFGPAMARSVPANAACFLAYEMTR 296
>sp|Q12289|CRC1_YEAST Mitochondrial carnitine carrier
Length = 327
Score = 155 bits (392), Expect = 1e-37
Identities = 97/247 (39%), Positives = 136/247 (55%), Gaps = 11/247 (4%)
Frame = +1
Query: 88 TLRNEGPVGFYKGMAAPLIGVTPMFAVCFFGYNLGRKL----QVKDENTPLTKPQIFAAG 255
TL GFYKG+ PL+GVTP+FAV F+GY++G+KL + + LT Q+ AAG
Sbjct: 89 TLFTNSVKGFYKGVIPPLLGVTPIFAVSFWGYDVGKKLVTFNNKQGGSNELTMGQMAAAG 148
Query: 256 MLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPG-DVIRKLYKEGGIRSIYKGTAAT 432
+S + TT + P ER+K +LQ KG + + KEGGI S++KG+ AT
Sbjct: 149 FISAIPTTLVTAPTERVKVVLQTSS--------KGSFIQAAKTIVKEGGIASLFKGSLAT 200
Query: 433 LLRDIPATGTYFMSYEWLKEILT-----PEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPP 597
L RD P + YF SYE K L + G ++ AGGIAGM WL P
Sbjct: 201 LARDGPGSALYFASYEISKNYLNSRQPRQDAGKDEPVNILNVCLAGGIAGMSMWLAVFPI 260
Query: 598 DTLKSRLQTAPEGKYPHGLRSVFREM-MANEGIVGLYRGVSPVLIRAFPANAACFLGYEV 774
DT+K++LQ + + + S +E+ + GI G + G+ P L+R+FPANAA FLG E+
Sbjct: 261 DTIKTKLQASSTRQ---NMLSATKEIYLQRGGIKGFFPGLGPALLRSFPANAATFLGVEM 317
Query: 775 SLKLLNK 795
+ L K
Sbjct: 318 THSLFKK 324
Score = 47.4 bits (111), Expect = 6e-05
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 7/91 (7%)
Frame = +1
Query: 538 RTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFRE-------MMANEGIV 696
++ AGG+ G+C P D +K R Q H + ++ +E + +
Sbjct: 37 KSFVAGGVGGVCAVFTGHPFDLIKVRCQNGQANSTVHAITNIIKEAKTQVKGTLFTNSVK 96
Query: 697 GLYRGVSPVLIRAFPANAACFLGYEVSLKLL 789
G Y+GV P L+ P A F GY+V KL+
Sbjct: 97 GFYKGVIPPLLGVTPIFAVSFWGYDVGKKLV 127
Score = 37.4 bits (85), Expect = 0.059
Identities = 34/151 (22%), Positives = 59/151 (39%), Gaps = 9/151 (5%)
Frame = +1
Query: 85 QTLRNEGPVG-FYKGMAAPLIGVTPMFAVCFFGYNLGRKL-------QVKDENTPLTKPQ 240
+T+ EG + +KG A L P A+ F Y + + Q ++ P+
Sbjct: 182 KTIVKEGGIASLFKGSLATLARDGPGSALYFASYEISKNYLNSRQPRQDAGKDEPVNILN 241
Query: 241 IFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLY-KEGGIRSIYK 417
+ AG ++G+ + P + IK LQ + +++Y + GGI+ +
Sbjct: 242 VCLAGGIAGMSMWLAVFPIDTIKTKLQASSTRQNMLS------ATKEIYLQRGGIKGFFP 295
Query: 418 GTAATLLRDIPATGTYFMSYEWLKEILTPEG 510
G LLR PA F+ E + G
Sbjct: 296 GLGPALLRSFPANAATFLGVEMTHSLFKKYG 326
>sp|Q9WVD5|ORNT1_MOUSE Mitochondrial ornithine transporter 1 (Solute carrier family 25
member 15)
Length = 301
Score = 153 bits (386), Expect = 7e-37
Identities = 94/271 (34%), Positives = 135/271 (49%), Gaps = 8/271 (2%)
Frame = +1
Query: 1 TLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVCFFG 180
T+KV++Q P +Y+GL DC L+T G GFYKG + LI +V F
Sbjct: 32 TMKVKMQTFP-------DLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIAENSVLFMC 84
Query: 181 YN----LGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQ----VQGAS 336
Y + RK+ D+ L+ Q AAG + F ++ P E +KC LQ ++ +
Sbjct: 85 YGFCQQVVRKVVGLDQQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSG 144
Query: 337 KEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEGGD 516
K V+++++++ G Y G ++TLLR++P +F YE L G
Sbjct: 145 KIAASQNTVWSVVKEIFRKDGPLGFYHGLSSTLLREVPGYFFFFGGYE-LSRSFFASGRS 203
Query: 517 KSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIV 696
K L P + +GG G+C WL P D +KSR+Q GL F ++ NEGI
Sbjct: 204 KDELGPVPLMLSGGFGGICLWLAVYPVDCIKSRIQVLSMTGKQTGLVRTFLSIVKNEGIT 263
Query: 697 GLYRGVSPVLIRAFPANAACFLGYEVSLKLL 789
LY G+ P +IRAFPAN A FL YE S KL+
Sbjct: 264 ALYSGLKPTMIRAFPANGALFLAYEYSRKLM 294
Score = 41.2 bits (95), Expect = 0.004
Identities = 27/85 (31%), Positives = 39/85 (45%)
Frame = +1
Query: 544 LFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPV 723
L AG G L P DT+K ++QT P+ GL + + G G Y+G SP
Sbjct: 13 LTAGAAGGTACVLTGQPFDTMKVKMQTFPD--LYRGLTDCCLKTYSQVGFRGFYKGTSPA 70
Query: 724 LIRAFPANAACFLGYEVSLKLLNKV 798
LI N+ F+ Y +++ KV
Sbjct: 71 LIANIAENSVLFMCYGFCQQVVRKV 95
Score = 35.4 bits (80), Expect = 0.22
Identities = 17/48 (35%), Positives = 22/48 (45%)
Frame = +1
Query: 64 GLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVCFFGYNLGRKLQV 207
GLV FL ++NEG Y G+ +I P F Y RKL +
Sbjct: 248 GLVRTFLSIVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMM 295
>sp|Q9Y619|ORNT1_HUMAN Mitochondrial ornithine transporter 1 (Solute carrier family 25,
member 15)
Length = 301
Score = 151 bits (382), Expect = 2e-36
Identities = 94/271 (34%), Positives = 133/271 (49%), Gaps = 8/271 (2%)
Frame = +1
Query: 1 TLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVCFFG 180
T+KV++Q P +Y+GL DC L+T G GFYKG + LI +V F
Sbjct: 32 TMKVKMQTFP-------DLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIAENSVLFMC 84
Query: 181 YN----LGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQ----VQGAS 336
Y + RK+ D+ L+ Q AAG + F ++ P E +KC LQ ++ +
Sbjct: 85 YGFCQQVVRKVAGLDKQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSG 144
Query: 337 KEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEGGD 516
K VI+ + ++ G Y G ++TLLR++P +F YE L G
Sbjct: 145 KIAKSQNTVWSVIKSILRKDGPLGFYHGLSSTLLREVPGYFFFFGGYE-LSRSFFASGRS 203
Query: 517 KSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIV 696
K L P + +GG+ G+C WL P D +KSR+Q G F ++ NEGI
Sbjct: 204 KDELGPVPLMLSGGVGGICLWLAVYPVDCIKSRIQVLSMSGKQAGFIRTFINVVKNEGIT 263
Query: 697 GLYRGVSPVLIRAFPANAACFLGYEVSLKLL 789
LY G+ P +IRAFPAN A FL YE S KL+
Sbjct: 264 ALYSGLKPTMIRAFPANGALFLAYEYSRKLM 294
Score = 41.2 bits (95), Expect = 0.004
Identities = 27/85 (31%), Positives = 39/85 (45%)
Frame = +1
Query: 544 LFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPV 723
L AG G L P DT+K ++QT P+ GL + + G G Y+G SP
Sbjct: 13 LTAGAAGGTACVLTGQPFDTMKVKMQTFPD--LYRGLTDCCLKTYSQVGFRGFYKGTSPA 70
Query: 724 LIRAFPANAACFLGYEVSLKLLNKV 798
LI N+ F+ Y +++ KV
Sbjct: 71 LIANIAENSVLFMCYGFCQQVVRKV 95
Score = 33.1 bits (74), Expect = 1.1
Identities = 14/48 (29%), Positives = 21/48 (43%)
Frame = +1
Query: 64 GLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVCFFGYNLGRKLQV 207
G + F+ ++NEG Y G+ +I P F Y RKL +
Sbjct: 248 GFIRTFINVVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMM 295
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 112,501,673
Number of Sequences: 369166
Number of extensions: 2540224
Number of successful extensions: 7390
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6236
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6779
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9318621220
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)