Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_P18
(934 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P30682|GNAI_LYMST Guanine nucleotide-binding protein G(i... 277 3e-74
sp|P51876|GNAI_HELTI Guanine nucleotide-binding protein G(i... 275 1e-73
sp|Q9DC51|GNAI3_MOUSE Guanine nucleotide-binding protein G(... 271 2e-72
sp|P30676|GNAI_ASTPE Guanine nucleotide-binding protein G(i... 271 2e-72
sp|P08753|GNAI3_RAT Guanine nucleotide-binding protein G(k)... 270 4e-72
sp|P08754|GNAI3_HUMAN Guanine nucleotide-binding protein G(... 270 4e-72
sp|P38401|GNAI1_CAVPO Guanine nucleotide-binding protein G(... 270 4e-72
sp|P63097|GNAI1_BOVIN Guanine nucleotide-binding protein G(... 269 7e-72
sp|Q5RAD4|GNAI1_PONPY Guanine nucleotide-binding protein G(... 269 7e-72
sp|P41776|GNAI_HOMAM Guanine nucleotide-binding protein G(i... 269 1e-71
>sp|P30682|GNAI_LYMST Guanine nucleotide-binding protein G(i), alpha subunit (Adenylate
cyclase-inhibiting G alpha protein)
Length = 354
Score = 277 bits (709), Expect = 3e-74
Identities = 134/205 (65%), Positives = 164/205 (80%)
Frame = +1
Query: 196 GAGESGKSTILKQMKIINNKGYTSEECLQYKPIVYSNTLQSLTAIIRAMGQIKIDFSNSE 375
GAGESGKSTI+KQMKII+ KGY+ EECLQYKP+VYSN +QS+ AII+AMGQ+KI F + +
Sbjct: 40 GAGESGKSTIVKQMKIIHEKGYSQEECLQYKPVVYSNAIQSMIAIIKAMGQLKIQFGHPD 99
Query: 376 RIEDARKVFSLGKNFEEAVLNEDIFAAMKRLWNDAGVVACFQRSREYQLNDSAEYFLNSL 555
R EDAR+ F+L + +E ++ ++ MKRLW D GV CF RSREYQLNDSAEY+LN+L
Sbjct: 100 RAEDARQFFALAGHADEGEMSAELSGIMKRLWKDVGVQECFSRSREYQLNDSAEYYLNAL 159
Query: 556 DRLSNFNYIPTEQDVLHTRVKTAGIVETIFSHKGLNLKIVDVGGQRSERRKWIHCFEGVM 735
DR+S YIPTEQDVL TRVKT GIVET F+ K L+ K+ DVGGQRSER+KWIHCFEGV
Sbjct: 160 DRISAPGYIPTEQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVT 219
Query: 736 TMIFVVAISEYDQFLIEDNEVHLTM 810
+IF+VA+SEYD L ED E++ M
Sbjct: 220 AIIFIVAMSEYDLTLAEDQEMNRMM 244
>sp|P51876|GNAI_HELTI Guanine nucleotide-binding protein G(i), alpha subunit (Adenylate
cyclase-inhibiting G alpha protein)
Length = 354
Score = 275 bits (703), Expect = 1e-73
Identities = 132/205 (64%), Positives = 164/205 (80%)
Frame = +1
Query: 196 GAGESGKSTILKQMKIINNKGYTSEECLQYKPIVYSNTLQSLTAIIRAMGQIKIDFSNSE 375
GAGESGKSTI+KQMKII+ KGY+ EECLQY P+VYSN +QS+ AII+AMGQ+KI F + +
Sbjct: 40 GAGESGKSTIVKQMKIIHEKGYSQEECLQYNPVVYSNAIQSMIAIIKAMGQLKIQFGHPD 99
Query: 376 RIEDARKVFSLGKNFEEAVLNEDIFAAMKRLWNDAGVVACFQRSREYQLNDSAEYFLNSL 555
R E+AR+ F+L + +E +++++ MKRLW D GV CF RSREYQLNDSAEY+LN+L
Sbjct: 100 RAEEARQFFALAGHADEGEMSQELSGIMKRLWKDVGVQECFSRSREYQLNDSAEYYLNAL 159
Query: 556 DRLSNFNYIPTEQDVLHTRVKTAGIVETIFSHKGLNLKIVDVGGQRSERRKWIHCFEGVM 735
DR+S YIPTEQDVL TRVKT GIVET F+ K L+ K+ DVGGQRSER+KWIHCFEGV
Sbjct: 160 DRISAPGYIPTEQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVT 219
Query: 736 TMIFVVAISEYDQFLIEDNEVHLTM 810
+IF+VA+SEYD L ED E++ M
Sbjct: 220 AIIFIVAMSEYDLTLAEDQEMNRMM 244
>sp|Q9DC51|GNAI3_MOUSE Guanine nucleotide-binding protein G(k), alpha subunit (G(i)
alpha-3)
Length = 354
Score = 271 bits (693), Expect = 2e-72
Identities = 131/202 (64%), Positives = 159/202 (78%)
Frame = +1
Query: 196 GAGESGKSTILKQMKIINNKGYTSEECLQYKPIVYSNTLQSLTAIIRAMGQIKIDFSNSE 375
GAGESGKSTI+KQMKII+ GY+ +EC QYK +VYSNT+QS+ AIIRAMG++KIDF S
Sbjct: 40 GAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGESA 99
Query: 376 RIEDARKVFSLGKNFEEAVLNEDIFAAMKRLWNDAGVVACFQRSREYQLNDSAEYFLNSL 555
R +DAR++F L + EE V+ ++ +KRLW D GV ACF RSREYQLNDSA Y+LN L
Sbjct: 100 RADDARQLFVLAGSAEEGVMTSELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDL 159
Query: 556 DRLSNFNYIPTEQDVLHTRVKTAGIVETIFSHKGLNLKIVDVGGQRSERRKWIHCFEGVM 735
DR+S NYIPT+QDVL TRVKT GIVET F+ K L K+ DVGGQRSER+KWIHCFEGV
Sbjct: 160 DRISQTNYIPTQQDVLRTRVKTTGIVETHFTFKELYFKMFDVGGQRSERKKWIHCFEGVT 219
Query: 736 TMIFVVAISEYDQFLIEDNEVH 801
+IF VA+S+YD L ED E++
Sbjct: 220 AIIFCVALSDYDLVLAEDEEMN 241
>sp|P30676|GNAI_ASTPE Guanine nucleotide-binding protein G(i), alpha subunit (Adenylate
cyclase-inhibiting G alpha protein)
Length = 354
Score = 271 bits (693), Expect = 2e-72
Identities = 130/202 (64%), Positives = 161/202 (79%)
Frame = +1
Query: 196 GAGESGKSTILKQMKIINNKGYTSEECLQYKPIVYSNTLQSLTAIIRAMGQIKIDFSNSE 375
GAGESGKSTI+KQMKII+ +GY+ E+C QYKP+VYSNT+QS+ AIIRAMG +K+DF + +
Sbjct: 40 GAGESGKSTIVKQMKIIHEEGYSEEDCKQYKPVVYSNTIQSMIAIIRAMGSLKVDFGDGD 99
Query: 376 RIEDARKVFSLGKNFEEAVLNEDIFAAMKRLWNDAGVVACFQRSREYQLNDSAEYFLNSL 555
R +DAR++F+L EE L+ ++ A MKRLW D GV CF RSREYQLNDSA Y+LN+L
Sbjct: 100 RTDDARQLFALAGQAEEGELSPELAAVMKRLWADGGVQGCFSRSREYQLNDSASYYLNAL 159
Query: 556 DRLSNFNYIPTEQDVLHTRVKTAGIVETIFSHKGLNLKIVDVGGQRSERRKWIHCFEGVM 735
DRL+ YIPT+QDVL TRVKT GIVET F+ K L+ K+ DVGGQRSER+KWIHCFEGV
Sbjct: 160 DRLAAPGYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVT 219
Query: 736 TMIFVVAISEYDQFLIEDNEVH 801
+IF VA+S YD L ED E++
Sbjct: 220 AIIFCVALSAYDLVLAEDEEMN 241
>sp|P08753|GNAI3_RAT Guanine nucleotide-binding protein G(k), alpha subunit (G(i)
alpha-3)
Length = 354
Score = 270 bits (690), Expect = 4e-72
Identities = 130/202 (64%), Positives = 159/202 (78%)
Frame = +1
Query: 196 GAGESGKSTILKQMKIINNKGYTSEECLQYKPIVYSNTLQSLTAIIRAMGQIKIDFSNSE 375
GAGESGKSTI+KQMKII+ GY+ +EC QYK +VYSNT+QS+ AIIRAMG++KIDF +
Sbjct: 40 GAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAA 99
Query: 376 RIEDARKVFSLGKNFEEAVLNEDIFAAMKRLWNDAGVVACFQRSREYQLNDSAEYFLNSL 555
R +DAR++F L + EE V+ ++ +KRLW D GV ACF RSREYQLNDSA Y+LN L
Sbjct: 100 RADDARQLFVLAGSAEEGVMTSELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDL 159
Query: 556 DRLSNFNYIPTEQDVLHTRVKTAGIVETIFSHKGLNLKIVDVGGQRSERRKWIHCFEGVM 735
DR+S NYIPT+QDVL TRVKT GIVET F+ K L K+ DVGGQRSER+KWIHCFEGV
Sbjct: 160 DRISQTNYIPTQQDVLRTRVKTTGIVETHFTFKELYFKMFDVGGQRSERKKWIHCFEGVT 219
Query: 736 TMIFVVAISEYDQFLIEDNEVH 801
+IF VA+S+YD L ED E++
Sbjct: 220 AIIFCVALSDYDLVLAEDEEMN 241
>sp|P08754|GNAI3_HUMAN Guanine nucleotide-binding protein G(k), alpha subunit (G(i)
alpha-3)
Length = 354
Score = 270 bits (690), Expect = 4e-72
Identities = 130/202 (64%), Positives = 159/202 (78%)
Frame = +1
Query: 196 GAGESGKSTILKQMKIINNKGYTSEECLQYKPIVYSNTLQSLTAIIRAMGQIKIDFSNSE 375
GAGESGKSTI+KQMKII+ GY+ +EC QYK +VYSNT+QS+ AIIRAMG++KIDF +
Sbjct: 40 GAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAA 99
Query: 376 RIEDARKVFSLGKNFEEAVLNEDIFAAMKRLWNDAGVVACFQRSREYQLNDSAEYFLNSL 555
R +DAR++F L + EE V+ ++ +KRLW D GV ACF RSREYQLNDSA Y+LN L
Sbjct: 100 RADDARQLFVLAGSAEEGVMTPELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDL 159
Query: 556 DRLSNFNYIPTEQDVLHTRVKTAGIVETIFSHKGLNLKIVDVGGQRSERRKWIHCFEGVM 735
DR+S NYIPT+QDVL TRVKT GIVET F+ K L K+ DVGGQRSER+KWIHCFEGV
Sbjct: 160 DRISQSNYIPTQQDVLRTRVKTTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVT 219
Query: 736 TMIFVVAISEYDQFLIEDNEVH 801
+IF VA+S+YD L ED E++
Sbjct: 220 AIIFCVALSDYDLVLAEDEEMN 241
>sp|P38401|GNAI1_CAVPO Guanine nucleotide-binding protein G(i), alpha-1 subunit (Adenylate
cyclase-inhibiting G alpha protein)
Length = 354
Score = 270 bits (690), Expect = 4e-72
Identities = 130/202 (64%), Positives = 160/202 (79%)
Frame = +1
Query: 196 GAGESGKSTILKQMKIINNKGYTSEECLQYKPIVYSNTLQSLTAIIRAMGQIKIDFSNSE 375
GAGESGKSTI+KQMKII+ GY+ EEC QYK +VYSNT+QS+ AIIRAMG++KIDF +S
Sbjct: 40 GAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSA 99
Query: 376 RIEDARKVFSLGKNFEEAVLNEDIFAAMKRLWNDAGVVACFQRSREYQLNDSAEYFLNSL 555
R +DAR++F L EE + ++ +KRLW D+GV ACF RSREYQLNDSA Y+LN L
Sbjct: 100 RADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDL 159
Query: 556 DRLSNFNYIPTEQDVLHTRVKTAGIVETIFSHKGLNLKIVDVGGQRSERRKWIHCFEGVM 735
DR++ NYIPT+QDVL TRVKT GIVET F+ K L+ K+ DVGGQRSER+KWIHCFEGV
Sbjct: 160 DRIAQSNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVT 219
Query: 736 TMIFVVAISEYDQFLIEDNEVH 801
+IF VA+S+YD L ED E++
Sbjct: 220 AIIFCVALSDYDLVLAEDEEMN 241
>sp|P63097|GNAI1_BOVIN Guanine nucleotide-binding protein G(i), alpha-1 subunit (Adenylate
cyclase-inhibiting G alpha protein)
sp|P63096|GNAI1_HUMAN Guanine nucleotide-binding protein G(i), alpha-1 subunit (Adenylate
cyclase-inhibiting G alpha protein)
Length = 354
Score = 269 bits (688), Expect = 7e-72
Identities = 130/202 (64%), Positives = 160/202 (79%)
Frame = +1
Query: 196 GAGESGKSTILKQMKIINNKGYTSEECLQYKPIVYSNTLQSLTAIIRAMGQIKIDFSNSE 375
GAGESGKSTI+KQMKII+ GY+ EEC QYK +VYSNT+QS+ AIIRAMG++KIDF +S
Sbjct: 40 GAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSA 99
Query: 376 RIEDARKVFSLGKNFEEAVLNEDIFAAMKRLWNDAGVVACFQRSREYQLNDSAEYFLNSL 555
R +DAR++F L EE + ++ +KRLW D+GV ACF RSREYQLNDSA Y+LN L
Sbjct: 100 RADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDL 159
Query: 556 DRLSNFNYIPTEQDVLHTRVKTAGIVETIFSHKGLNLKIVDVGGQRSERRKWIHCFEGVM 735
DR++ NYIPT+QDVL TRVKT GIVET F+ K L+ K+ DVGGQRSER+KWIHCFEGV
Sbjct: 160 DRIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVT 219
Query: 736 TMIFVVAISEYDQFLIEDNEVH 801
+IF VA+S+YD L ED E++
Sbjct: 220 AIIFCVALSDYDLVLAEDEEMN 241
>sp|Q5RAD4|GNAI1_PONPY Guanine nucleotide-binding protein G(i), alpha-1 subunit (Adenylate
cyclase-inhibiting G alpha protein)
Length = 354
Score = 269 bits (688), Expect = 7e-72
Identities = 130/202 (64%), Positives = 160/202 (79%)
Frame = +1
Query: 196 GAGESGKSTILKQMKIINNKGYTSEECLQYKPIVYSNTLQSLTAIIRAMGQIKIDFSNSE 375
GAGESGKSTI+KQMKII+ GY+ EEC QYK +VYSNT+QS+ AIIRAMG++KIDF +S
Sbjct: 40 GAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSA 99
Query: 376 RIEDARKVFSLGKNFEEAVLNEDIFAAMKRLWNDAGVVACFQRSREYQLNDSAEYFLNSL 555
R +DAR++F L EE + ++ +KRLW D+GV ACF RSREYQLNDSA Y+LN L
Sbjct: 100 RADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDL 159
Query: 556 DRLSNFNYIPTEQDVLHTRVKTAGIVETIFSHKGLNLKIVDVGGQRSERRKWIHCFEGVM 735
DR++ NYIPT+QDVL TRVKT GIVET F+ K L+ K+ DVGGQRSER+KWIHCFEGV
Sbjct: 160 DRIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVT 219
Query: 736 TMIFVVAISEYDQFLIEDNEVH 801
+IF VA+S+YD L ED E++
Sbjct: 220 AIIFCVALSDYDLVLAEDEEMN 241
>sp|P41776|GNAI_HOMAM Guanine nucleotide-binding protein G(i), alpha subunit (Adenylate
cyclase-inhibiting G alpha protein)
Length = 355
Score = 269 bits (687), Expect = 1e-71
Identities = 132/202 (65%), Positives = 159/202 (78%)
Frame = +1
Query: 196 GAGESGKSTILKQMKIINNKGYTSEECLQYKPIVYSNTLQSLTAIIRAMGQIKIDFSNSE 375
GAGESGKSTI+KQMKII+ GY+ EEC QY+P+VYSNT+QSL AIIRAMGQ+KIDF +S
Sbjct: 41 GAGESGKSTIVKQMKIIHETGYSREECEQYRPVVYSNTIQSLMAIIRAMGQLKIDFRDSS 100
Query: 376 RIEDARKVFSLGKNFEEAVLNEDIFAAMKRLWNDAGVVACFQRSREYQLNDSAEYFLNSL 555
R +DAR F+L +E L ++ MKRLWN++GV C RSREYQLND+A Y+LN+L
Sbjct: 101 RADDARHFFTLASAADEGELTPELANIMKRLWNESGVQHCRNRSREYQLNDTAAYYLNAL 160
Query: 556 DRLSNFNYIPTEQDVLHTRVKTAGIVETIFSHKGLNLKIVDVGGQRSERRKWIHCFEGVM 735
DR++ YIPT+QDVL TRVKT GIVET FS K LN K+ DVGGQRSER+KWIHCFEGV
Sbjct: 161 DRIARPGYIPTQQDVLRTRVKTTGIVETNFSFKNLNFKLFDVGGQRSERKKWIHCFEGVT 220
Query: 736 TMIFVVAISEYDQFLIEDNEVH 801
+IFVVA+S YD L ED E++
Sbjct: 221 AIIFVVALSGYDLVLAEDEEMN 242
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,020,222
Number of Sequences: 369166
Number of extensions: 1675519
Number of successful extensions: 3962
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3640
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3808
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9606826000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)