Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_O18
(716 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P31230|MCA1_MOUSE Multisynthetase complex auxiliary comp... 178 1e-44
sp|O54873|MCA1_CRIGR Multisynthetase complex auxiliary comp... 172 1e-42
sp|Q12904|MCA1_HUMAN Multisynthetase complex auxiliary comp... 166 4e-41
sp|Q20970|SYM_CAEEL Methionyl-tRNA synthetase (Methionine--... 160 4e-39
sp|Q91WQ3|SYYC_MOUSE Tyrosyl-tRNA synthetase, cytoplasmic (... 148 2e-35
sp|P54577|SYYC_HUMAN Tyrosyl-tRNA synthetase, cytoplasmic (... 148 2e-35
sp|Q29465|SYYC_BOVIN Tyrosyl-tRNA synthetase, cytoplasmic (... 147 4e-35
sp|Q9SVN5|SYM_ARATH Probable methionyl-tRNA synthetase (Met... 141 2e-33
sp|Q9ZTS1|SYM_ORYSA Probable methionyl-tRNA synthetase (Met... 115 2e-25
sp|P46672|G4P1_YEAST GU4 nucleic-binding protein 1 (G4p1 pr... 100 7e-21
>sp|P31230|MCA1_MOUSE Multisynthetase complex auxiliary component p43 [Contains:
Endothelial monocyte-activating polypeptide II (EMAP-II)
(Small inducible cytokine subfamily E member 1)]
Length = 310
Score = 178 bits (452), Expect = 1e-44
Identities = 97/214 (45%), Positives = 133/214 (62%), Gaps = 3/214 (1%)
Frame = +2
Query: 11 PVLKKCTKSEPVNEKKVDAVKVTPPV---IKAEKSVKPKEPATKDKSKEDGKAQPKSNEA 181
P+ CT SE V + A +P IKA + K KE K K++ + ++
Sbjct: 85 PLQTNCTASESVVQSPSVATTASPATKEQIKAGEEKKVKEKTEKKGEKKEKQQSAAASTD 144
Query: 182 SEVIDISRFNMRIGKIIEITKHAEADSLYVEQVDVGEAKPRQIISGLVKYCTESDLLGRM 361
S+ ID SR ++RIG I+ KH +ADSLYVE+VDVGEA PR ++SGLV + + RM
Sbjct: 145 SKPIDASRLDLRIGCIVTAKKHPDADSLYVEEVDVGEAAPRTVVSGLVNHVPLEQMQNRM 204
Query: 362 AVFLINLKPAKMRGIMSEGMIMCASSPEQGVVEPLMVPEGVKPGDIVTVEGFNYKPDDIM 541
V L NLKPAKMRG++S+ M+MCASSPE+ VE L P G PGD +T + F +PD +
Sbjct: 205 VVLLCNLKPAKMRGVLSQAMVMCASSPEK--VEILAPPNGSVPGDRITFDAFPGEPDKEL 262
Query: 542 NPKKKILETVKPDLKVDENGIATYRGARWQVNGQ 643
NPKKKI E ++PDL + +ATY+GA ++V G+
Sbjct: 263 NPKKKIWEQIQPDLHTNAECVATYKGAPFEVKGK 296
>sp|O54873|MCA1_CRIGR Multisynthetase complex auxiliary component p43 [Contains:
Endothelial monocyte-activating polypeptide II (EMAP-II)
(Small inducible cytokine subfamily E member 1)]
Length = 359
Score = 172 bits (435), Expect = 1e-42
Identities = 89/179 (49%), Positives = 122/179 (68%), Gaps = 1/179 (0%)
Frame = +2
Query: 110 KPKEPATKDKSKEDGKAQPKSNEA-SEVIDISRFNMRIGKIIEITKHAEADSLYVEQVDV 286
K KE K K++ K Q + A S+ +D+SR ++RIG+I+ + KH +ADSLYVE+VDV
Sbjct: 169 KVKEKTDKKGEKKEKKLQSAAPSADSKPVDVSRLDLRIGRIVTVKKHPDADSLYVEEVDV 228
Query: 287 GEAKPRQIISGLVKYCTESDLLGRMAVFLINLKPAKMRGIMSEGMIMCASSPEQGVVEPL 466
GEA PR +ISGLV + + RM V L NLKPAKMRGI+S+ M+MCASSPE+ VE L
Sbjct: 229 GEAAPRTVISGLVNHVPLDQMQNRMVVLLCNLKPAKMRGILSQAMVMCASSPEK--VEIL 286
Query: 467 MVPEGVKPGDIVTVEGFNYKPDDIMNPKKKILETVKPDLKVDENGIATYRGARWQVNGQ 643
P G PGD +T + F +PD +NPKKKI E ++PDL + +ATY+G+ ++V G+
Sbjct: 287 APPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNAECVATYKGSPFEVKGK 345
>sp|Q12904|MCA1_HUMAN Multisynthetase complex auxiliary component p43 [Contains:
Endothelial monocyte-activating polypeptide II (EMAP-II)
(Small inducible cytokine subfamily E member 1)]
Length = 312
Score = 166 bits (421), Expect = 4e-41
Identities = 86/179 (48%), Positives = 119/179 (66%), Gaps = 1/179 (0%)
Frame = +2
Query: 110 KPKEPATKDKSKEDGKAQPKSNEA-SEVIDISRFNMRIGKIIEITKHAEADSLYVEQVDV 286
K KE K K++ K Q + A S+ ID+SR ++RIG II KH +ADSLYVE+VDV
Sbjct: 122 KAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVDV 181
Query: 287 GEAKPRQIISGLVKYCTESDLLGRMAVFLINLKPAKMRGIMSEGMIMCASSPEQGVVEPL 466
GE PR ++SGLV + + RM + L NLKPAKMRG++S+ M+MCASSPE+ +E L
Sbjct: 182 GEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEK--IEIL 239
Query: 467 MVPEGVKPGDIVTVEGFNYKPDDIMNPKKKILETVKPDLKVDENGIATYRGARWQVNGQ 643
P G PGD +T + F +PD +NPKKKI E ++PDL ++ +ATY+G ++V G+
Sbjct: 240 APPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGK 298
>sp|Q20970|SYM_CAEEL Methionyl-tRNA synthetase (Methionine--tRNA ligase) (MetRS)
Length = 917
Score = 160 bits (404), Expect = 4e-39
Identities = 82/179 (45%), Positives = 115/179 (64%)
Frame = +2
Query: 83 PVIKAEKSVKPKEPATKDKSKEDGKAQPKSNEASEVIDISRFNMRIGKIIEITKHAEADS 262
P +A + P EP K K ++ GK + + ID+ R +MR+G+II+ KH +AD+
Sbjct: 720 PKKEAPSTPAPSEPK-KAKEQKKGKGGAAAAPVDDTIDVGRLDMRVGRIIKCEKHPDADA 778
Query: 263 LYVEQVDVGEAKPRQIISGLVKYCTESDLLGRMAVFLINLKPAKMRGIMSEGMIMCASSP 442
LYVEQ+DVGE+ PR ++SGLV++ + R+ V L NLKPAKMRG+ S M+MCASSP
Sbjct: 779 LYVEQIDVGESAPRTVVSGLVRHVPLDQMQNRLVVVLCNLKPAKMRGVESRAMVMCASSP 838
Query: 443 EQGVVEPLMVPEGVKPGDIVTVEGFNYKPDDIMNPKKKILETVKPDLKVDENGIATYRG 619
++ VE + VP KPG V + ++PD+ +NPKKKI ETV DLKV G A ++G
Sbjct: 839 DK--VEIMEVPADSKPGTPVVCPPYTHRPDEQLNPKKKIWETVAEDLKVSAEGFAEWKG 895
>sp|Q91WQ3|SYYC_MOUSE Tyrosyl-tRNA synthetase, cytoplasmic (Tyrosyl--tRNA ligase) (TyrRS)
Length = 528
Score = 148 bits (373), Expect = 2e-35
Identities = 82/186 (44%), Positives = 120/186 (64%), Gaps = 4/186 (2%)
Frame = +2
Query: 71 KVTPPVIKAEKSVKPKEPATKDKSKEDGKAQPKSNEASEVIDISRFNMRIGKIIEITKHA 250
K P +K S +P+ K K K K++E EVI SR ++R+GKI+ + KH
Sbjct: 327 KFNTPALKKLASAAYPDPS---KQKPPAKGPAKNSEPEEVIP-SRLDIRVGKILSVEKHP 382
Query: 251 EADSLYVEQVDVGEAKPRQIISGLVKYCTESDLLGRMAVFLINLKPAKMRGIMSEGMIMC 430
+ADSLYVE++DVGEA+PR ++SGLV++ + +L R+ V L NLKP KMRG+ S+GM++C
Sbjct: 383 DADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLVVVLCNLKPQKMRGVDSQGMLLC 442
Query: 431 ASSPEQGV---VEPLMVPEGVKPGDIVTVEGFNY-KPDDIMNPKKKILETVKPDLKVDEN 598
AS +GV VEPL P G PG+ V V+G+ +PD+ + PKKK+ E ++ D K+ E
Sbjct: 443 AS--VEGVSRQVEPLDPPAGSAPGERVFVQGYEKGQPDEELKPKKKVFEKLQADFKISEE 500
Query: 599 GIATYR 616
IA ++
Sbjct: 501 CIAQWK 506
>sp|P54577|SYYC_HUMAN Tyrosyl-tRNA synthetase, cytoplasmic (Tyrosyl--tRNA ligase) (TyrRS)
Length = 528
Score = 148 bits (373), Expect = 2e-35
Identities = 86/205 (41%), Positives = 127/205 (61%), Gaps = 4/205 (1%)
Frame = +2
Query: 71 KVTPPVIKAEKSVKPKEPATKDKSKEDGKAQPKSNEASEVIDISRFNMRIGKIIEITKHA 250
K P +K S +P+ K K K K++E EVI SR ++R+GKII + KH
Sbjct: 327 KFNTPALKKLASAAYPDPS---KQKPMAKGPAKNSEPEEVIP-SRLDIRVGKIITVEKHP 382
Query: 251 EADSLYVEQVDVGEAKPRQIISGLVKYCTESDLLGRMAVFLINLKPAKMRGIMSEGMIMC 430
+ADSLYVE++DVGEA+PR ++SGLV++ + +L R+ V L NLKP KMRG+ S+GM++C
Sbjct: 383 DADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLVVVLCNLKPQKMRGVESQGMLLC 442
Query: 431 ASSPEQGV---VEPLMVPEGVKPGDIVTVEGFNY-KPDDIMNPKKKILETVKPDLKVDEN 598
AS +G+ VEPL P G PG+ V V+G+ +PD+ + PKKK+ E ++ D K+ E
Sbjct: 443 ASI--EGINRQVEPLDPPAGSAPGEHVFVKGYEKGQPDEELKPKKKVFEKLQADFKISEE 500
Query: 599 GIATYRGARWQVNGQAGAIISTKLK 673
IA ++ + + G+I LK
Sbjct: 501 CIAQWKQTNFMT--KLGSISCKSLK 523
>sp|Q29465|SYYC_BOVIN Tyrosyl-tRNA synthetase, cytoplasmic (Tyrosyl--tRNA ligase) (TyrRS)
Length = 528
Score = 147 bits (370), Expect = 4e-35
Identities = 84/205 (40%), Positives = 127/205 (61%), Gaps = 4/205 (1%)
Frame = +2
Query: 71 KVTPPVIKAEKSVKPKEPATKDKSKEDGKAQPKSNEASEVIDISRFNMRIGKIIEITKHA 250
K P +K S +P+ K K K K++E EVI SR ++R+GK+I + KH
Sbjct: 327 KFNTPALKKLSSAAYPDPS---KQKPAVKGPAKNSEPEEVIP-SRLDIRVGKVISVDKHP 382
Query: 251 EADSLYVEQVDVGEAKPRQIISGLVKYCTESDLLGRMAVFLINLKPAKMRGIMSEGMIMC 430
+ADSLYVE++DVGEA+PR ++SGLV++ + +L R+ V L NLKP KMRG+ S+GM++C
Sbjct: 383 DADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLVVVLCNLKPQKMRGVKSQGMLLC 442
Query: 431 ASSPEQGV---VEPLMVPEGVKPGDIVTVEGFNY-KPDDIMNPKKKILETVKPDLKVDEN 598
AS +GV VEPL P G PG+ V V+G+ +PD+ + PKKK+ E ++ D K+ +
Sbjct: 443 AS--VEGVNRKVEPLDPPAGSAPGERVFVKGYEKGQPDEELKPKKKVFEKLQADFKISDE 500
Query: 599 GIATYRGARWQVNGQAGAIISTKLK 673
IA ++ + + G++ LK
Sbjct: 501 YIAQWKQTNFMT--KMGSVSCKSLK 523
>sp|Q9SVN5|SYM_ARATH Probable methionyl-tRNA synthetase (Methionine--tRNA ligase) (MetRS)
Length = 797
Score = 141 bits (356), Expect = 2e-33
Identities = 72/165 (43%), Positives = 107/165 (64%), Gaps = 1/165 (0%)
Frame = +2
Query: 125 ATKDKSKEDGKAQPKSNEASE-VIDISRFNMRIGKIIEITKHAEADSLYVEQVDVGEAKP 301
A K K+ G +PK A++ I ++R ++R+GKI++ KH +AD+LYVE++DVG +
Sbjct: 611 AKKQKASSKGGGKPKPQPAADREITMARLDIRVGKIVKAEKHPKADALYVEEIDVGGGEI 670
Query: 302 RQIISGLVKYCTESDLLGRMAVFLINLKPAKMRGIMSEGMIMCASSPEQGVVEPLMVPEG 481
R ++SGLVKY ++ RM L NLKPAKMR I+S+ M++ ASS + VE + P+
Sbjct: 671 RTVVSGLVKYIPLEEMQNRMVCVLCNLKPAKMRDIVSQAMVLAASSSDGSKVELVEPPKT 730
Query: 482 VKPGDIVTVEGFNYKPDDIMNPKKKILETVKPDLKVDENGIATYR 616
G+ VT GF +PDD++NPKKK+ ET+ DL EN +A Y+
Sbjct: 731 ANIGERVTFPGFEGEPDDVLNPKKKVWETLLVDLNTKENLVACYK 775
>sp|Q9ZTS1|SYM_ORYSA Probable methionyl-tRNA synthetase (Methionine--tRNA ligase) (MetRS)
Length = 804
Score = 115 bits (287), Expect = 2e-25
Identities = 59/162 (36%), Positives = 96/162 (59%)
Frame = +2
Query: 131 KDKSKEDGKAQPKSNEASEVIDISRFNMRIGKIIEITKHAEADSLYVEQVDVGEAKPRQI 310
K++ K+ G ++ K+ E + +++ ++R+G I + KH +ADSLYVE++DVGE PR +
Sbjct: 623 KEQKKQSGGSKSKNAEVD--VTVAKLDIRVGLIRKAQKHPDADSLYVEEIDVGEEAPRTV 680
Query: 311 ISGLVKYCTESDLLGRMAVFLINLKPAKMRGIMSEGMIMCASSPEQGVVEPLMVPEGVKP 490
+SGLVK+ ++ R L NLKP MRGI S M++ AS+ + VE + PE
Sbjct: 681 VSGLVKFIPLEEMQNRKVCVLCNLKPVAMRGIKSHAMVLAASNEDHTKVELVEPPESAAV 740
Query: 491 GDIVTVEGFNYKPDDIMNPKKKILETVKPDLKVDENGIATYR 616
G+ VT G++ +P+ +N K K E + DL + +A Y+
Sbjct: 741 GERVTFAGYSGEPEASLNAKSKTWEKLSADLHSNGELVACYK 782
>sp|P46672|G4P1_YEAST GU4 nucleic-binding protein 1 (G4p1 protein) (P42) (ARC1 protein)
Length = 376
Score = 99.8 bits (247), Expect = 7e-21
Identities = 70/197 (35%), Positives = 104/197 (52%), Gaps = 3/197 (1%)
Frame = +2
Query: 14 VLKKCTKSE-PVNEKKVDAVKVTPPVIKAEKSVKPKEPATKDKSKEDGKAQPKSNEASEV 190
V KK K + P + + +K KA+K+ K K+ + Q + N+A E
Sbjct: 152 VSKKAKKQDHPRGKPDEETLKKLREEAKAKKAAK--------KAANAKQQQEQQNKAPEK 203
Query: 191 IDISRFNMRIGKIIEITKHAEADSLYVEQVDVGEAK-PRQIISGLVKYCTESDLLGRMAV 367
S + R+G I + KH +ADSLYV +DVG+ + PR + SGLVK+ + R V
Sbjct: 204 PKPSAIDFRVGFIQKAIKHPDADSLYVSTIDVGDEEGPRTVCSGLVKHFPLDAMQERYVV 263
Query: 368 FLINLKPAKMRGIMSEGMIMCASSPEQGVVEPLMVPEGVKPGDIVTVEGF-NYKPDDIMN 544
+ NLKP MRGI S M++C S+ ++ VE + P+ K GD V EGF + P +N
Sbjct: 264 VVCNLKPVNMRGIKSTAMVLCGSNDDK--VEFVEPPKDSKAGDKVFFEGFGDEAPMKQLN 321
Query: 545 PKKKILETVKPDLKVDE 595
PKKKI E ++P ++
Sbjct: 322 PKKKIWEHLQPHFTTND 338
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,230,550
Number of Sequences: 369166
Number of extensions: 1377342
Number of successful extensions: 5488
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5111
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5376
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6365071885
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)