Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_O16-2
(339 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q14019|COTL1_HUMAN Coactosin-like protein 103 9e-23
sp|Q9CQI6|COTL1_MOUSE Coactosin-like protein 100 1e-21
sp|P34121|COAC_DICDI Coactosin (Cytoskeletal p17 protein) (... 79 3e-15
sp|Q9P7E8|APP1_SCHPO Protein app1 46 2e-05
sp|Q9JHL4|DBNL_RAT Drebrin-like protein (SH3 domain-contain... 39 0.003
sp|Q62418|DBNL_MOUSE Drebrin-like protein (SH3 domain-conta... 39 0.003
sp|Q9UJU6|DBNL_HUMAN Drebrin-like protein (SH3 domain-conta... 39 0.005
sp|Q07266|DREB_RAT Drebrin (Developmentally regulated brain... 33 0.27
sp|Q16643|DREB_HUMAN Drebrin (Developmentally regulated bra... 33 0.27
sp|Q9QXS6|DREB_MOUSE Drebrin (Developmentally regulated bra... 33 0.27
>sp|Q14019|COTL1_HUMAN Coactosin-like protein
Length = 142
Score = 103 bits (258), Expect = 9e-23
Identities = 54/109 (49%), Positives = 69/109 (63%)
Frame = +2
Query: 2 MTSKIDKETISEAYEDVRNDATETTWALFGYDDKKIVVVKTGTLYESLLAEFNDDERHFA 181
M +KIDKE AY VR+D + W F YD IV + G Y+ + + DD R FA
Sbjct: 1 MATKIDKEACRAAYNLVRDDGSAVIWVTFKYDGSTIVPGEQGAEYQHFIQQCTDDVRLFA 60
Query: 182 FVRMITGDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYA 328
FVR TGD MSKR+KFALIT+ G NVS +++A DK+LVKEVV ++A
Sbjct: 61 FVRFTTGDAMSKRSKFALITWIGENVSGLQRAKTGTDKTLVKEVVQNFA 109
>sp|Q9CQI6|COTL1_MOUSE Coactosin-like protein
Length = 142
Score = 100 bits (249), Expect = 1e-21
Identities = 53/109 (48%), Positives = 68/109 (62%)
Frame = +2
Query: 2 MTSKIDKETISEAYEDVRNDATETTWALFGYDDKKIVVVKTGTLYESLLAEFNDDERHFA 181
M +KIDKE AY VR+D + W F YD IV G Y+ + + DD R FA
Sbjct: 1 MATKIDKEACRAAYNLVRDDGSAVIWVTFRYDGATIVPGDQGADYQHFIQQCTDDVRLFA 60
Query: 182 FVRMITGDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYA 328
FVR TGD MSKR+KFALIT+ G +VS +++A DK+LVKEVV ++A
Sbjct: 61 FVRFTTGDAMSKRSKFALITWIGEDVSGLQRAKTGTDKTLVKEVVQNFA 109
>sp|P34121|COAC_DICDI Coactosin (Cytoskeletal p17 protein) (Cyclic AMP-regulated protein
p16)
Length = 146
Score = 79.0 bits (193), Expect = 3e-15
Identities = 39/111 (35%), Positives = 68/111 (61%), Gaps = 3/111 (2%)
Frame = +2
Query: 14 IDKETISEAYEDVRNDATETTWALFGYDDKKIVVV--KTGTLYESLLAEFND-DERHFAF 184
+ + AY++V D+ +T W LF Y+ K +V+ K + L E N ER +A+
Sbjct: 4 VSSTELKAAYDEVLADSNDTNWCLFKYEGKNKIVLSGKGSGGFAELAQEINQPSERLYAY 63
Query: 185 VRMITGDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDL 337
+R+++GD+ SKR+KF I++CG V + KAN++V K+ VK+V+ + V++
Sbjct: 64 LRVVSGDDESKRSKFVFISWCGEEVGPLAKANVSVHKASVKQVIKNIGVEV 114
>sp|Q9P7E8|APP1_SCHPO Protein app1
Length = 857
Score = 46.2 bits (108), Expect = 2e-05
Identities = 32/119 (26%), Positives = 60/119 (50%), Gaps = 7/119 (5%)
Frame = +2
Query: 2 MTSKIDKET----ISEAYEDVRNDATETTWALFGYDDKK---IVVVKTGTLYESLLAEFN 160
M+ ++D T I YE V + A + +WA+FGY+ + + VV +G + L EF+
Sbjct: 1 MSFQLDTSTHGAEIRNVYEKVLSGADDCSWAIFGYEKGQGNILKVVASGNDNDEFLDEFD 60
Query: 161 DDERHFAFVRMITGDEMSKRAKFALITYCGANVSVMKKANLTVDKSLVKEVVASYAVDL 337
++ F F+R+ D + KF L+ +CG + +K ++ + V ++ Y V +
Sbjct: 61 ENAVLFGFLRV--KDVNTGLNKFVLVCWCGE--AAARKGLFSIHMATVSNLLKGYHVQI 115
>sp|Q9JHL4|DBNL_RAT Drebrin-like protein (SH3 domain-containing protein 7)
Length = 436
Score = 39.3 bits (90), Expect = 0.003
Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Frame = +2
Query: 29 ISEAYEDVRNDATETTWALFGYDDKKIVVVKTGT---LYESLLAEFNDDERHFAFVRMIT 199
+ EAY V + + T WALF Y+ + GT E L+ E N + +AF R+
Sbjct: 12 LQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEELVEELNSGKVMYAFCRV-- 69
Query: 200 GDEMSKRAKFALITYCGANVSVMKK 274
D S KF LI + G V+ ++K
Sbjct: 70 KDPNSGLPKFVLINWTGEGVNDVRK 94
>sp|Q62418|DBNL_MOUSE Drebrin-like protein (SH3 domain-containing protein 7)
(Actin-binding protein 1)
Length = 436
Score = 39.3 bits (90), Expect = 0.003
Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Frame = +2
Query: 29 ISEAYEDVRNDATETTWALFGYDDKKIVVVKTGT---LYESLLAEFNDDERHFAFVRMIT 199
+ EAY V + + T WALF Y+ + GT E L+ E N + +AF R+
Sbjct: 12 LQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEELVEELNSGKVMYAFCRV-- 69
Query: 200 GDEMSKRAKFALITYCGANVSVMKK 274
D S KF LI + G V+ ++K
Sbjct: 70 KDPNSGLPKFVLINWTGEGVNDVRK 94
>sp|Q9UJU6|DBNL_HUMAN Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F)
(Cervical SH3P7) (HPK1-interacting protein of 55 kDa)
(HIP-55) (Cervical mucin-associated protein)
Length = 430
Score = 38.5 bits (88), Expect = 0.005
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Frame = +2
Query: 29 ISEAYEDVRNDATETTWALFGYDDKKIVVVKTGT---LYESLLAEFNDDERHFAFVRMIT 199
+ EAY V + + T WALF Y+ + GT E ++ E N + +AF R+
Sbjct: 12 LQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEEMVEELNSGKVMYAFCRV-- 69
Query: 200 GDEMSKRAKFALITYCGANVSVMKK 274
D S KF LI + G V+ ++K
Sbjct: 70 KDPNSGLPKFVLINWTGEGVNDVRK 94
>sp|Q07266|DREB_RAT Drebrin (Developmentally regulated brain protein)
Length = 707
Score = 32.7 bits (73), Expect = 0.27
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +2
Query: 38 AYEDVRNDATETTWALFGY----DDKKIVVVKTGTLYESLLAEFNDDERHFAFVRMITGD 205
AYE+V + + WAL+ Y DD K+ G L E L F + + + F + D
Sbjct: 16 AYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQE-LSGHFENQKVMYGFCSV--KD 72
Query: 206 EMSKRAKFALITYCGANVSVMKK 274
+ K+ LI + G +V +K
Sbjct: 73 SQAALPKYVLINWVGEDVPDARK 95
>sp|Q16643|DREB_HUMAN Drebrin (Developmentally regulated brain protein)
Length = 649
Score = 32.7 bits (73), Expect = 0.27
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +2
Query: 38 AYEDVRNDATETTWALFGY----DDKKIVVVKTGTLYESLLAEFNDDERHFAFVRMITGD 205
AYE+V + + WAL+ Y DD K+ G L E L F + + + F + D
Sbjct: 16 AYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQE-LSGHFENQKVMYGFCSV--KD 72
Query: 206 EMSKRAKFALITYCGANVSVMKK 274
+ K+ LI + G +V +K
Sbjct: 73 SQAALPKYVLINWVGEDVPDARK 95
>sp|Q9QXS6|DREB_MOUSE Drebrin (Developmentally regulated brain protein)
Length = 706
Score = 32.7 bits (73), Expect = 0.27
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +2
Query: 38 AYEDVRNDATETTWALFGY----DDKKIVVVKTGTLYESLLAEFNDDERHFAFVRMITGD 205
AYE+V + + WAL+ Y DD K+ G L E L F + + + F + D
Sbjct: 16 AYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQE-LSGHFENQKVMYGFCSV--KD 72
Query: 206 EMSKRAKFALITYCGANVSVMKK 274
+ K+ LI + G +V +K
Sbjct: 73 SQAALPKYVLINWVGEDVPDARK 95
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,456,475
Number of Sequences: 369166
Number of extensions: 471315
Number of successful extensions: 1478
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1464
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1477
length of database: 68,354,980
effective HSP length: 80
effective length of database: 53,576,180
effective search space used: 1714437760
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)