Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_O10
(817 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein ... 159 7e-39
sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 ... 158 1e-38
sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 ... 157 3e-38
sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1) 149 7e-36
sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1) 149 7e-36
sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1) 149 9e-36
sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein ... 119 1e-26
sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprote... 74 5e-13
sp|Q921F4|HNRLL_MOUSE Heterogeneous nuclear ribonucleoprote... 69 1e-11
sp|Q8R081|HNRPL_MOUSE Heterogeneous nuclear ribonucleoprote... 67 4e-11
>sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I) (57 kDa RNA-binding
protein PPTB-1)
Length = 531
Score = 159 bits (403), Expect = 7e-39
Identities = 87/196 (44%), Positives = 117/196 (59%), Gaps = 1/196 (0%)
Frame = +1
Query: 232 QRINPDALFILFGMFS*LI*LPYSLIDFNNSFTVGVYGDVQRVKILYNKKNTALIQFVDG 411
+R+ P +LFILFG VYGDVQRVKIL+NKK AL+Q DG
Sbjct: 347 ERVTPQSLFILFG----------------------VYGDVQRVKILFNKKENALVQMADG 384
Query: 412 EHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATS 591
A A+++LN L+GKP+R+ SKH ++ +P+ E Q L KDY NS LHRFK+ S
Sbjct: 385 NQAQLAMSHLNGHKLHGKPIRITLSKHQNVQLPR-EGQEDQGLTKDYGNSPLHRFKKPGS 443
Query: 592 RTVQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDFVITKVKMINPNQRKMALVQMESVEM 768
+ QNI+PP LHL+ +P S E+D++ LF + + K RKMAL+QM SVE
Sbjct: 444 KNFQNIFPPSATLHLSNIPPSVSEEDLKVLFSSNGGVVKGFKFFQKDRKMALIQMGSVEE 503
Query: 769 AIDALIKLHDYDAGSS 816
A+ ALI LH++D G +
Sbjct: 504 AVQALIDLHNHDLGEN 519
>sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I) (Pyrimidine-binding
protein) (PYBP)
Length = 555
Score = 158 bits (400), Expect = 1e-38
Identities = 86/196 (43%), Positives = 118/196 (60%), Gaps = 1/196 (0%)
Frame = +1
Query: 232 QRINPDALFILFGMFS*LI*LPYSLIDFNNSFTVGVYGDVQRVKILYNKKNTALIQFVDG 411
+R+ P +LFILFG VYGDVQRVKIL+NKK AL++ DG
Sbjct: 371 ERVTPQSLFILFG----------------------VYGDVQRVKILFNKKENALVEMADG 408
Query: 412 EHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATS 591
A A+++LN L+GK +R+ SKH S+ +P+ E Q L KDY +S LHRFK+ S
Sbjct: 409 SQAQLAMSHLNGHKLHGKSVRITLSKHQSVQLPR-EGQEDQGLTKDYGSSPLHRFKKPGS 467
Query: 592 RTVQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDFVITKVKMINPNQRKMALVQMESVEM 768
+ QNI+PP LHL+ +P S EDD+++LF + + K RKMAL+QM SVE
Sbjct: 468 KNFQNIFPPSATLHLSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKDRKMALIQMGSVEE 527
Query: 769 AIDALIKLHDYDAGSS 816
A+ ALI+LH++D G +
Sbjct: 528 AVQALIELHNHDLGEN 543
>sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I)
Length = 557
Score = 157 bits (397), Expect = 3e-38
Identities = 88/196 (44%), Positives = 116/196 (59%), Gaps = 1/196 (0%)
Frame = +1
Query: 232 QRINPDALFILFGMFS*LI*LPYSLIDFNNSFTVGVYGDVQRVKILYNKKNTALIQFVDG 411
+R+ P +LFILFG VY DVQRVKIL+NKK AL+Q DG
Sbjct: 373 ERVTPQSLFILFG----------------------VYCDVQRVKILFNKKENALVQMADG 410
Query: 412 EHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATS 591
A A+++LN L+GKP+R+ SKH ++ +P+ E Q L KDY NS LHRFK+ S
Sbjct: 411 SQAQLAMSHLNGHKLHGKPVRITLSKHQNVQLPR-EGQEDQGLTKDYGNSPLHRFKKPGS 469
Query: 592 RTVQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDFVITKVKMINPNQRKMALVQMESVEM 768
+ QNI+PP LHL+ +P S E+D++ LF + I K RKMAL+QM SVE
Sbjct: 470 KNFQNIFPPSATLHLSNIPPSISEEDLKILFSSNGGIVKGFKFFQKDRKMALIQMGSVEE 529
Query: 769 AIDALIKLHDYDAGSS 816
AI ALI LH++D G +
Sbjct: 530 AIQALIDLHNHDLGEN 545
>sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1)
Length = 523
Score = 149 bits (377), Expect = 7e-36
Identities = 85/194 (43%), Positives = 110/194 (56%), Gaps = 1/194 (0%)
Frame = +1
Query: 238 INPDALFILFGMFS*LI*LPYSLIDFNNSFTVGVYGDVQRVKILYNKKNTALIQFVDGEH 417
I P LFILFG VYGDV RVKI++NKK AL+Q D
Sbjct: 341 ITPHGLFILFG----------------------VYGDVHRVKIMFNKKENALVQMADASQ 378
Query: 418 ASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRT 597
A A+ +L+ LYGK +R SKH ++ +P+ E Q L KD+SNS LHRFK+ S+
Sbjct: 379 AQLAMNHLSGQRLYGKVLRATLSKHQAVQLPR-EGQEDQGLTKDFSNSPLHRFKKPGSKN 437
Query: 598 VQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDFVITKVKMINPNQRKMALVQMESVEMAI 774
QNI+PP LHL+ +P S DD++NLF E K RKMAL+Q+ SVE AI
Sbjct: 438 FQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAI 497
Query: 775 DALIKLHDYDAGSS 816
ALI+LH++D G +
Sbjct: 498 QALIELHNHDLGEN 511
>sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1)
Length = 521
Score = 149 bits (377), Expect = 7e-36
Identities = 85/194 (43%), Positives = 110/194 (56%), Gaps = 1/194 (0%)
Frame = +1
Query: 238 INPDALFILFGMFS*LI*LPYSLIDFNNSFTVGVYGDVQRVKILYNKKNTALIQFVDGEH 417
I P LFILFG VYGDV RVKI++NKK AL+Q D
Sbjct: 339 ITPHGLFILFG----------------------VYGDVHRVKIMFNKKENALVQMADANQ 376
Query: 418 ASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRT 597
A A+ +L+ LYGK +R SKH ++ +P+ E Q L KD+SNS LHRFK+ S+
Sbjct: 377 AQLAMNHLSGQRLYGKVLRATLSKHQAVQLPR-EGQEDQGLTKDFSNSPLHRFKKPGSKN 435
Query: 598 VQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDFVITKVKMINPNQRKMALVQMESVEMAI 774
QNI+PP LHL+ +P S DD++NLF E K RKMAL+Q+ SVE AI
Sbjct: 436 FQNIFPPSATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAI 495
Query: 775 DALIKLHDYDAGSS 816
ALI+LH++D G +
Sbjct: 496 QALIELHNHDLGEN 509
>sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1)
Length = 523
Score = 149 bits (376), Expect = 9e-36
Identities = 85/194 (43%), Positives = 110/194 (56%), Gaps = 1/194 (0%)
Frame = +1
Query: 238 INPDALFILFGMFS*LI*LPYSLIDFNNSFTVGVYGDVQRVKILYNKKNTALIQFVDGEH 417
I P LFILFG VYGDV RVKI++NKK AL+Q D
Sbjct: 341 ITPHGLFILFG----------------------VYGDVHRVKIMFNKKENALVQMADASQ 378
Query: 418 ASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRT 597
A A+ +L+ LYGK +R SKH ++ +P+ E Q L KD+SNS LHRFK+ S+
Sbjct: 379 AQIAMNHLSGQRLYGKVLRATLSKHQAVQLPR-EGQEDQGLTKDFSNSPLHRFKKPGSKN 437
Query: 598 VQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDFVITKVKMINPNQRKMALVQMESVEMAI 774
QNI+PP LHL+ +P S DD++NLF E K RKMAL+Q+ SVE AI
Sbjct: 438 FQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAI 497
Query: 775 DALIKLHDYDAGSS 816
ALI+LH++D G +
Sbjct: 498 QALIELHNHDLGEN 511
>sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I)
Length = 527
Score = 119 bits (298), Expect = 1e-26
Identities = 75/196 (38%), Positives = 104/196 (53%), Gaps = 1/196 (0%)
Frame = +1
Query: 232 QRINPDALFILFGMFS*LI*LPYSLIDFNNSFTVGVYGDVQRVKILYNKKNTALIQFVDG 411
+R+ P +LFILFG VYGDVQRVKIL+NKK AL+Q DG
Sbjct: 345 ERVTPQSLFILFG----------------------VYGDVQRVKILFNKKENALVQMADG 382
Query: 412 EHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATS 591
A + + + + +++ S E Q L KDY +S L RFK+ S
Sbjct: 383 SQAQ--LGEPPERAQAAREVSAHYTVQASECAAAREGQEDQGLTKDYGSSPL-RFKKPGS 439
Query: 592 RTVQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDFVITKVKMINPNQRKMALVQMESVEM 768
+ QNI+PP LHL+ +P S EDD+++LF + + K RKMAL+QM SVE
Sbjct: 440 KNFQNIFPPSATLHLSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKDRKMALIQMGSVEE 499
Query: 769 AIDALIKLHDYDAGSS 816
A+ ALI+LH++D G +
Sbjct: 500 AVQALIELHNHDLGEN 515
>sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprotein L-like (Stromal
RNA-regulating factor) (BLOCK24 protein)
Length = 542
Score = 73.9 bits (180), Expect = 5e-13
Identities = 51/162 (31%), Positives = 83/162 (51%), Gaps = 7/162 (4%)
Frame = +1
Query: 337 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSK-HTSISMPK 513
+YG++++VK + TAL++ D RAVT+LNNV L+GK + V SK H+ +
Sbjct: 358 LYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHSVVPSQI 417
Query: 514 PEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLFED- 690
E ++ KD++ S+ +RF A + I PP VLH +P E+ L D
Sbjct: 418 FELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDH 477
Query: 691 ----FVITKVKMINPNQRKMA-LVQMESVEMAIDALIKLHDY 801
F+ KV P+ + ++ L++ E A++AL L+ Y
Sbjct: 478 EVLTFIKYKVFDAKPSAKTLSGLLEWECKTDAVEALTALNHY 519
>sp|Q921F4|HNRLL_MOUSE Heterogeneous nuclear ribonucleoprotein L-like
Length = 591
Score = 69.3 bits (168), Expect = 1e-11
Identities = 49/162 (30%), Positives = 82/162 (50%), Gaps = 7/162 (4%)
Frame = +1
Query: 337 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSK-HTSISMPK 513
+YG++++VK + TAL++ D RAVT+LNNV L+GK + V SK H+ +
Sbjct: 407 LYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHSVVPSQI 466
Query: 514 PEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLFED- 690
E ++ KD++ S+ +RF A + I PP VLH +P E+ L D
Sbjct: 467 FELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDH 526
Query: 691 ----FVITKVKMINPNQRKMA-LVQMESVEMAIDALIKLHDY 801
F+ KV + + ++ L++ + A++AL L+ Y
Sbjct: 527 EVLPFIKYKVFDAKASAKTLSGLLEWKCKTDAVEALTALNHY 568
>sp|Q8R081|HNRPL_MOUSE Heterogeneous nuclear ribonucleoprotein L (hnRNP L)
Length = 555
Score = 67.4 bits (163), Expect = 4e-11
Identities = 48/163 (29%), Positives = 81/163 (49%), Gaps = 8/163 (4%)
Frame = +1
Query: 337 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKP 516
+YG+V++VK + +K A+++ DG RA+T+LNN ++G+ M V SK +I MP
Sbjct: 371 LYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKMNVCVSKQPAI-MPGQ 429
Query: 517 E---EQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLFE 687
E S KD+S SR +RF I P VLH P E++ + +
Sbjct: 430 SYGLEDGSCSY-KDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICD 488
Query: 688 DFVI---TKVKMINPNQRKMA--LVQMESVEMAIDALIKLHDY 801
+ + T VK+ + + + L++ +S A++ L L+ Y
Sbjct: 489 ELGVKRPTSVKVFSGKSERSSSGLLEWDSKSDALETLGFLNHY 531
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,125,040
Number of Sequences: 369166
Number of extensions: 1595350
Number of successful extensions: 3694
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3495
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3666
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7811456130
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)