Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_O03
(735 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q6PHI9|RAB4A_BRARE Ras-related protein Rab-4A 170 4e-42
sp|Q68EK7|RAB4B_BRARE Ras-related protein Rab-4B 169 7e-42
sp|P20338|RAB4A_HUMAN Ras-related protein Rab-4A 169 7e-42
sp|P56371|RAB4A_MOUSE Ras-related protein Rab-4A 168 2e-41
sp|P05714|RAB4A_RAT Ras-related protein Rab-4A 164 2e-40
sp|P51146|RAB4B_RAT Ras-related protein Rab-4B >gi|46577105... 164 3e-40
sp|P61018|RAB4B_HUMAN Ras-related protein Rab-4B >gi|465776... 163 5e-40
sp|Q9GP33|RAB4A_ECHMU Probable Ras-related protein Rab-4A 157 4e-38
sp|Q91V41|RAB14_MOUSE Ras-related protein Rab-14 150 4e-36
sp|P61107|RAB14_RAT Ras-related protein Rab-14 >gi|46577643... 150 4e-36
>sp|Q6PHI9|RAB4A_BRARE Ras-related protein Rab-4A
Length = 213
Score = 170 bits (430), Expect = 4e-42
Identities = 81/135 (60%), Positives = 109/135 (80%)
Frame = +2
Query: 2 SKIIQVNNRTIKLQIWDTAGQERFRSVARSYYRGASGALVVYDITNRDSFNAVINWLSDA 181
SKII V N+ +KLQIWDTAGQERFRSV RSYYRGA+GAL+VYDIT+R+++NA+ NWL+DA
Sbjct: 47 SKIISVVNKFVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDA 106
Query: 182 KSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFSKENEMQFYETSAVNGEHIDDVFI 361
+ LA N+ IL GNKKDL A REV++ EA F++ENE+ F ETSA+ GE++++ F+
Sbjct: 107 RMLASQNIVIILCGNKKDL---DADREVTFLEASRFAQENELMFLETSALTGENVEEAFV 163
Query: 362 ECARAVVSKWESNDL 406
+CAR +++K ES +L
Sbjct: 164 QCARKILNKIESGEL 178
>sp|Q68EK7|RAB4B_BRARE Ras-related protein Rab-4B
Length = 213
Score = 169 bits (428), Expect = 7e-42
Identities = 78/135 (57%), Positives = 110/135 (81%)
Frame = +2
Query: 2 SKIIQVNNRTIKLQIWDTAGQERFRSVARSYYRGASGALVVYDITNRDSFNAVINWLSDA 181
S+++ V +T+KLQIWDTAGQERFRSV RSYYRGA+GAL+VYDIT+R+++NA+ NWL+DA
Sbjct: 47 SRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDA 106
Query: 182 KSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFSKENEMQFYETSAVNGEHIDDVFI 361
++LA N+ IL GNKKDL A REV++ EA F++ENE+ F ETSA+ GE++++ F+
Sbjct: 107 RTLASPNIVIILCGNKKDL---DADREVTFLEASRFAQENELMFLETSALTGENVEEAFL 163
Query: 362 ECARAVVSKWESNDL 406
+CAR++ +K ES +L
Sbjct: 164 KCARSIPNKIESGEL 178
>sp|P20338|RAB4A_HUMAN Ras-related protein Rab-4A
Length = 213
Score = 169 bits (428), Expect = 7e-42
Identities = 93/181 (51%), Positives = 124/181 (68%), Gaps = 1/181 (0%)
Frame = +2
Query: 2 SKIIQVNNRTIKLQIWDTAGQERFRSVARSYYRGASGALVVYDITNRDSFNAVINWLSDA 181
SKII V + +KLQIWDTAGQERFRSV RSYYRGA+GAL+VYDIT+R+++NA+ NWL+DA
Sbjct: 47 SKIINVGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDA 106
Query: 182 KSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFSKENEMQFYETSAVNGEHIDDVFI 361
+ LA N+ IL GNKKDL A REV++ EA F++ENE+ F ETSA+ GE++++ F+
Sbjct: 107 RMLASQNIVIILCGNKKDL---DADREVTFLEASRFAQENELMFLETSALTGENVEEAFV 163
Query: 362 ECARAVVSKWESNDLSDNIAQNSSSQNSGDIRKRWNRLSGSPAGGIRLSRARA-NSSNCQ 538
+CAR +++K ES +L + S GD R R SP RA+A N+ C
Sbjct: 164 QCARKILNKIESGELDPE--RMGSGIQYGDAALRQLR---SP------RRAQAPNAQECG 212
Query: 539 C 541
C
Sbjct: 213 C 213
>sp|P56371|RAB4A_MOUSE Ras-related protein Rab-4A
Length = 213
Score = 168 bits (425), Expect = 2e-41
Identities = 80/135 (59%), Positives = 108/135 (80%)
Frame = +2
Query: 2 SKIIQVNNRTIKLQIWDTAGQERFRSVARSYYRGASGALVVYDITNRDSFNAVINWLSDA 181
SKII V + +KLQIWDTAGQERFRSV RSYYRGA+GAL+VYDIT+R+++NA+ NWL+DA
Sbjct: 47 SKIINVGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDA 106
Query: 182 KSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFSKENEMQFYETSAVNGEHIDDVFI 361
+ LA N+ IL GNKKDL A REV++ EA F++ENE+ F ETSA+ GE++++ F+
Sbjct: 107 RMLASQNIVLILCGNKKDL---DADREVTFLEASRFAQENELMFLETSALTGENVEEAFM 163
Query: 362 ECARAVVSKWESNDL 406
+CAR +++K ES +L
Sbjct: 164 QCARKILNKIESGEL 178
>sp|P05714|RAB4A_RAT Ras-related protein Rab-4A
Length = 213
Score = 164 bits (415), Expect = 2e-40
Identities = 78/134 (58%), Positives = 106/134 (79%)
Frame = +2
Query: 5 KIIQVNNRTIKLQIWDTAGQERFRSVARSYYRGASGALVVYDITNRDSFNAVINWLSDAK 184
KII V + +KLQIWDTAGQERFRSV SYYRGA+GAL+VYDIT+R+++NA+ NWL+DA+
Sbjct: 48 KIINVGGKYVKLQIWDTAGQERFRSVTTSYYRGAAGALLVYDITSRETYNALTNWLTDAR 107
Query: 185 SLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFSKENEMQFYETSAVNGEHIDDVFIE 364
LA N+ IL GNKKDL A REV++ EA F++ENE+ F ETSA+ GE++++ F++
Sbjct: 108 MLASQNIVIILCGNKKDL---DADREVTFLEASRFAQENELMFLETSALTGENVEEAFMQ 164
Query: 365 CARAVVSKWESNDL 406
CAR +++K ES +L
Sbjct: 165 CARKILNKIESGEL 178
>sp|P51146|RAB4B_RAT Ras-related protein Rab-4B
sp|Q91ZR1|RAB4B_MOUSE Ras-related protein Rab-4B
Length = 213
Score = 164 bits (414), Expect = 3e-40
Identities = 79/154 (51%), Positives = 114/154 (74%)
Frame = +2
Query: 2 SKIIQVNNRTIKLQIWDTAGQERFRSVARSYYRGASGALVVYDITNRDSFNAVINWLSDA 181
S+++ V +T+KLQIWDTAGQERFRSV RSYYRGA+GAL+VYDIT+R+++N++ WL+DA
Sbjct: 47 SRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDA 106
Query: 182 KSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFSKENEMQFYETSAVNGEHIDDVFI 361
++LA N+ IL GNKKDL REV++ EA F++ENE+ F ETSA+ GE++++ F+
Sbjct: 107 RTLASPNIVVILCGNKKDL---DPEREVTFLEASRFAQENELMFLETSALTGENVEEAFL 163
Query: 362 ECARAVVSKWESNDLSDNIAQNSSSQNSGDIRKR 463
+CAR +++K +S +L + S GDI R
Sbjct: 164 KCARTILNKIDSGELDPE--RMGSGIQYGDISLR 195
>sp|P61018|RAB4B_HUMAN Ras-related protein Rab-4B
sp|P61017|RAB4B_CANFA Ras-related protein Rab-4B
Length = 213
Score = 163 bits (412), Expect = 5e-40
Identities = 74/135 (54%), Positives = 108/135 (80%)
Frame = +2
Query: 2 SKIIQVNNRTIKLQIWDTAGQERFRSVARSYYRGASGALVVYDITNRDSFNAVINWLSDA 181
S+++ V +T+KLQIWDTAGQERFRSV RSYYRGA+GAL+VYDIT+R+++N++ WL+DA
Sbjct: 47 SRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDA 106
Query: 182 KSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFSKENEMQFYETSAVNGEHIDDVFI 361
++LA N+ IL GNKKDL REV++ EA F++ENE+ F ETSA+ GE++++ F+
Sbjct: 107 RTLASPNIVVILCGNKKDL---DPEREVTFLEASRFAQENELMFLETSALTGENVEEAFL 163
Query: 362 ECARAVVSKWESNDL 406
+CAR +++K +S +L
Sbjct: 164 KCARTILNKIDSGEL 178
>sp|Q9GP33|RAB4A_ECHMU Probable Ras-related protein Rab-4A
Length = 223
Score = 157 bits (396), Expect = 4e-38
Identities = 86/181 (47%), Positives = 115/181 (63%), Gaps = 1/181 (0%)
Frame = +2
Query: 2 SKIIQVNNRTIKLQIWDTAGQERFRSVARSYYRGASGALVVYDITNRDSFNAVINWLSDA 181
S++I V+ +K+QIWDTAGQERFRS+ARSYY A G L+VYDITNR SF AV WL DA
Sbjct: 48 SRVISVDGTHVKIQIWDTAGQERFRSMARSYYHDAVGTLLVYDITNRTSFGAVEQWLGDA 107
Query: 182 KSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFSKENEMQFYETSAVNGEHIDDVFI 361
+ LA + ILVGNKKDL D +V++ EA F++EN +QF ETSA+ GE+IDD F
Sbjct: 108 RHLATPGVVVILVGNKKDLRD--TDGQVTHWEANTFAQENGLQFIETSALTGENIDDAFT 165
Query: 362 ECARAVVSKWESNDL-SDNIAQNSSSQNSGDIRKRWNRLSGSPAGGIRLSRARANSSNCQ 538
C R ++SK +S +L +D + S+ Q+ + S + + S A A+S C
Sbjct: 166 SCVRVLLSKVKSGELGADRLLVGSNKQHLQAVNL---TASATSVSASQSSAATAHSDTCL 222
Query: 539 C 541
C
Sbjct: 223 C 223
>sp|Q91V41|RAB14_MOUSE Ras-related protein Rab-14
Length = 215
Score = 150 bits (378), Expect = 4e-36
Identities = 77/180 (42%), Positives = 111/180 (61%)
Frame = +2
Query: 2 SKIIQVNNRTIKLQIWDTAGQERFRSVARSYYRGASGALVVYDITNRDSFNAVINWLSDA 181
++II+V+ + IKLQIWDTAGQERFR+V RSYYRGA+GAL+VYDIT R ++N + +WL+DA
Sbjct: 50 TRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDA 109
Query: 182 KSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFSKENEMQFYETSAVNGEHIDDVFI 361
++L N IL+GNK AD +A R+V+Y EA+ F++EN + F E SA GE+++D F+
Sbjct: 110 RNLTNPNTVIILIGNK---ADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFL 166
Query: 362 ECARAVVSKWESNDLSDNIAQNSSSQNSGDIRKRWNRLSGSPAGGIRLSRARANSSNCQC 541
E A+ + + L N A++ +P GG S + C C
Sbjct: 167 EAAKKIYQNIQDGSLDLNAAESGVQHK-----------PSAPQGGRLTSEPQPQREGCGC 215
>sp|P61107|RAB14_RAT Ras-related protein Rab-14
sp|P61106|RAB14_HUMAN Ras-related protein Rab-14
Length = 215
Score = 150 bits (378), Expect = 4e-36
Identities = 77/180 (42%), Positives = 111/180 (61%)
Frame = +2
Query: 2 SKIIQVNNRTIKLQIWDTAGQERFRSVARSYYRGASGALVVYDITNRDSFNAVINWLSDA 181
++II+V+ + IKLQIWDTAGQERFR+V RSYYRGA+GAL+VYDIT R ++N + +WL+DA
Sbjct: 50 TRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDA 109
Query: 182 KSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFSKENEMQFYETSAVNGEHIDDVFI 361
++L N IL+GNK AD +A R+V+Y EA+ F++EN + F E SA GE+++D F+
Sbjct: 110 RNLTNPNTVIILIGNK---ADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFL 166
Query: 362 ECARAVVSKWESNDLSDNIAQNSSSQNSGDIRKRWNRLSGSPAGGIRLSRARANSSNCQC 541
E A+ + + L N A++ +P GG S + C C
Sbjct: 167 EAAKKIYQNIQDGSLDLNAAESGVQHK-----------PSAPQGGRLTSEPQPQREGCGC 215
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,504,874
Number of Sequences: 369166
Number of extensions: 1631998
Number of successful extensions: 4804
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4506
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4609
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6582889600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)